International Journal of Advanced Research in Medicine最新文献_第3页

The relation between serum irisin levels with the anthropometric and metabolic parameters in obese and non-obese patients with type 2 diabetes mellitus 肥胖和非肥胖 2 型糖尿病患者血清鸢尾素水平与人体测量指标和代谢指标的关系

International Journal of Advanced Research in Medicine Pub Date : 2023-10-01 DOI: 10.22271/27069567.2023.v5.i4a.518

Mahrous Mohammed Elmetwaly, S. M. Aboelnasr, Ghada Abd Almomen Soliman, Ingy Abd Elwahab Ibrahim

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Haemovigilance in pregnancy: A prospective observational study in a secondary care hospital 孕期血液警戒：一家二级医院的前瞻性观察研究

International Journal of Advanced Research in Medicine Pub Date : 2023-10-01 DOI: 10.22271/27069567.2023.v5.i4a.520

Sathyapriyadharisini R, Gopalakrishnan Vr, Swadhin Ranjan Behera

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A brief report on a case of Cerebrotendinous Xanthomatosis 一例脑黄瘤病的简要报告

International Journal of Advanced Research in Medicine Pub Date : 2023-10-01 DOI: 10.22271/27069567.2023.v5.i4a.516

Dr. Srinidhi Kondepudi

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Sedation treatment in critical care unit evolved over time 重症监护室的镇静治疗随着时间的推移而演变

International Journal of Advanced Research in Medicine Pub Date : 2023-10-01 DOI: 10.22271/27069567.2023.v5.i4a.515

Dr. Ehab AbouAlazayem Abdelsalam Mohamed Shalaby

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An Observational Study to Assess the Predictors of Cardiac Dysfunction in Type 2 Diabetes Patients 评估2型糖尿病患者心功能障碍预测因素的观察性研究

International Journal of Advanced Research in Medicine Pub Date : 2023-08-29 DOI: 10.24321/2349.7181.202302

Mudit Chauhan

{"title":"An Observational Study to Assess the Predictors of Cardiac Dysfunction in Type 2 Diabetes Patients","authors":"Mudit Chauhan","doi":"10.24321/2349.7181.202302","DOIUrl":"https://doi.org/10.24321/2349.7181.202302","url":null,"abstract":"Introduction: Diabetes mellitus is a chronic metabolic disorder characterised by elevated blood glucose levels (hyperglycaemia) resulting from either insufficient insulin production or ineffective insulin utilisation by the body. Cardiac dysfunction refers to abnormalities in the structure or function of the heart, leading to impaired pumping ability and compromised circulation. The relationship between diabetes mellitus and cardiac dysfunction is complex and involves multiple factors, including metabolic, molecular, and cellular mechanisms. Aim: The aim of this study was to identify the predictors of cardiac dysfunction in patients with type 2 diabetes mellitus (T2DM). Material and Methods: The study employed an observational design and included a sample size of 284 participants with type 2 diabetes. It included T2DM patients (> 10 years of duration of the disease) who were more than 40 years of age. Result: The results showed a significant positive association between the age group of 61-80 years and abnormal/ elevated levels of B-type natriuretic peptide (BNP) [odds ratio (OR): 2.32; confidence interval (CI): 1.013 ± 3.301; p value: 0.039]. Furthermore, an increase in the duration of T2DM (21-30 years) was significantly associated with abnormal/ elevated BNP levels (> 100) [OR: 3.283; CI: 1.704 ± 3.827; p value: 0.003]. Conclusion: This study links BNP to ejection fraction (EF) in T2DM patients without heart failure symptoms. It also shows that elevated BNP is associated with reduced EF, and normal BNP is linked to preserved EF. It was seen that age, T2DM duration, and HbA1c impact BNP levels. Longer T2DM duration was found to be associated with lower EF. How to cite this article: Chaudhary AK, Singh RK, Singh A, Chauhan M. An Observational Study to Assess the Predictors of Cardiac Dysfunction in Type 2 Diabetes Patients. J Adv Res Med. 2023;10(1):1-8. DOI: https://doi.org/10.24321/2349.7181.202302","PeriodicalId":13835,"journal":{"name":"International Journal of Advanced Research in Medicine","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136349496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Assessment of Cardiac Function in Pregnant Females of a Tertiary Care Hospital of East Uttar Pradesh: A Cross-sectional Study 东北方邦三级医院孕妇心功能评估:一项横断面研究

International Journal of Advanced Research in Medicine Pub Date : 2023-08-23 DOI: 10.24321/2349.7181.202301

Mudit Chauhan

{"title":"Assessment of Cardiac Function in Pregnant Females of a Tertiary Care Hospital of East Uttar Pradesh: A Cross-sectional Study","authors":"Mudit Chauhan","doi":"10.24321/2349.7181.202301","DOIUrl":"https://doi.org/10.24321/2349.7181.202301","url":null,"abstract":"Introduction: Cardiovascular dysfunction, including heart failure (HF), is a significant contributor to maternal mortality and is a leading non- obstetric cause of death during pregnancy. The rates of cardiovascular disease (CVD) mortality have been increasing over the years, surpassing other pregnancy-related causes of death.Objectives: The study was conducted to assess the cardiac function in pregnant females during their third trimester and determine the prevalence of cardiac disease among pregnant women.Methods: The study was conducted among 260 pregnant women in their third trimester who were selected as per the predefined inclusion and exclusion criteria. A thorough physical examination was done and presenting complaints such as chest pain, breathlessness, palpitations, syncope, easy fatiguability, swelling of legs, orthopnoea, and paroxysmal nocturnal dyspnoea along with few biochemical markers were documented. Data collected during the study period, which spanned from July 1, 2021, to June 30, 2022, were subjected to appropriate statistical analysis.Results: The study had predominantly lower socioeconomic housewives (63.1% multigravida and 36.9% primigravida). Cardiac symptoms were present in 4.6% of the subjects. About 5.8% had chronic cardiac conditions, among whom, congenital heart issues were seen in 26.7%, while 73.3% had acquired heart disease. Atrial septal defect was the most common congenital condition, and rheumatic heart disease, particularly mitral  stenosis and regurgitation, prevailed in acquired cases.Conclusion: The study demonstrated a 5.8% prevalence of cardiac disease in pregnant women during their third trimester, with acquired heart disease, particularly rheumatic heart disease, being more common than congenital heart disease.","PeriodicalId":13835,"journal":{"name":"International Journal of Advanced Research in Medicine","volume":"147 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135619653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Role of saphenous nerve block in knee osteoarthritis 隐神经阻滞在膝关节骨关节炎中的作用

International Journal of Advanced Research in Medicine Pub Date : 2023-07-01 DOI: 10.22271/27069567.2023.v5.i3a.496

S. Khallaf, S. E. A. E. Ghany, A. Y. Ahmed, Ali Eid El Deeb, Mervat Abd El Satar El Sergany

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Kyasanur Forest Disease in India: Robust prevention and control strategy is the need of the hour 印度的Kyasanur森林疾病:强有力的预防和控制战略是当务之急

International Journal of Advanced Research in Medicine Pub Date : 2023-07-01 DOI: 10.22271/27069567.2023.v5.i3a.500

Sumeet Juneja

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Significance of ambulatory and home blood pressure monitoring in hypertension management: An Indian perspective 动态和家庭血压监测在高血压管理中的意义:一个印度人的观点

International Journal of Advanced Research in Medicine Pub Date : 2023-07-01 DOI: 10.22271/27069567.2023.v5.i3a.493

Rajeev Garg, Sunil Sathe

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Studying the protective role of resveratrol against D-galactose-induced renal damage in male albino rats 研究白藜芦醇对d -半乳糖致雄性白化大鼠肾损害的保护作用

International Journal of Advanced Research in Medicine Pub Date : 2023-07-01 DOI: 10.22271/27069567.2023.v5.i3a.491

Rana Mohamed ElSetiha, Ghada Mahmoud Ismaeal, M. Emam, Wael Mohamed El Mashad

{"title":"Studying the protective role of resveratrol against D-galactose-induced renal damage in male albino rats","authors":"Rana Mohamed ElSetiha, Ghada Mahmoud Ismaeal, M. Emam, Wael Mohamed El Mashad","doi":"10.22271/27069567.2023.v5.i3a.491","DOIUrl":"https://doi.org/10.22271/27069567.2023.v5.i3a.491","url":null,"abstract":"Background: Chronic kidney disease is a significant global health issue with a sharply rising incidence, although modern medicine has made enormous strides, there are still several limitations to kidney disease prevention and therapy. The objective of this research was to investigate resveratrol's potential protective results against d-galactose-induced kidney injury in male albino rats. Methods: Forty adult male albino rats were used in this study (weighing 150 – 200 g). All rats were split into four equal groups, as follows: group I (Control group): injected with 0.9% saline subcutaneously every day for eight weeks, group II (D-gal group): received 120 mg/kg D‐gal in 0.9% saline subcutaneously every day for eight weeks, group III (Res group): received resveratrol at a dose of (50 mg/kg/day) dissolved in saline 0.9 % via oral gavage for eight weeks, group IV (D-gal + Res group): received D-gal subcutaneously and oral resveratrol daily for eight weeks in the same doses as in groups II and III. Results: group II (D-gal group) demonstrated significant rise in serum creatinine level, BUN, TNF-α level and renal MDA level with significant drop in renal GPx level while group IV (D-gal + Res) revealed significant decline in serum creatinine, BUN, TNF-α and renal MDA levels with significant increase in the renal GPx level. Conclusions: Resveratrol effectively protects the kidney tissues against d-galactose-induced injury in aging rats.","PeriodicalId":13835,"journal":{"name":"International Journal of Advanced Research in Medicine","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82929640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0