International archives of allergy and applied immunology最新文献_第10页

Beta-2-adrenoceptors of polymorphonuclear leukocytes in children with atopic dermatitis. Their number and affinity to the radioligand [125I]-cyanopindolol. 儿童特应性皮炎中多形核白细胞的β -2肾上腺素受体。它们的数目和对放射性配体[125I]-氰吲哚的亲和力。

International archives of allergy and applied immunology Pub Date : 1991-01-01 DOI: 10.1159/000235439

A Pohl, J Otto, R Urbanek

引用次数: 7

Synthesis of biologically active recombinant Der f II. 生物活性重组Der fⅱ的合成。

International archives of allergy and applied immunology Pub Date : 1991-01-01 DOI: 10.1159/000235401

T Yuuki, Y Okumura, T Ando, H Yamakawa, M Suko, M Haida, M Dohi, H Okudaira

引用次数: 9

Control of eosinophilia. 嗜酸性粒细胞的控制。

International archives of allergy and applied immunology Pub Date : 1991-01-01 DOI: 10.1159/000235342

C J Sanderson

引用次数: 29

Comparative antigen analysis of different life stages of Schistosoma mansoni by crossed immunoelectrophoresis. 曼氏血吸虫不同生命期抗原的交叉免疫电泳比较分析。

International archives of allergy and applied immunology Pub Date : 1991-01-01 DOI: 10.1159/000235440

A A Akhiani, L A Nilsson, O Ouchterlony

{"title":"Comparative antigen analysis of different life stages of Schistosoma mansoni by crossed immunoelectrophoresis.","authors":"A A Akhiani, L A Nilsson, O Ouchterlony","doi":"10.1159/000235440","DOIUrl":"https://doi.org/10.1159/000235440","url":null,"abstract":"<p><p>Two-dimensional (crossed) immunoelectrophoresis was used for analysis of soluble antigen extracts obtained from the three developmental stages, cercariae, adult worms and eggs, of Schistosoma mansoni by using homologous hyperimmune sera produced in sheep. The antigenic relationships between the three stages as well as the possible relationship to the intermediate snail host were studied. Seven antigen components were shown to be shared between all three life stages of S. mansoni. Furthermore, one antigen was common to adult worm and snail, and one other antigen was shared between cercaria and snail. By using an intermediate gel containing lectin in the antigen-antibody system or by enzyme staining of the immune precipitates it was possible to identify schistosome antigens possessing lectin reactivity or enzyme activity. Characterization of enzyme activities revealed three individual precipitating antigens in adult worm of S. mansoni possessing esterase, leucyl-glycyl-glycine peptidase and phenylalanyl-leucine peptidase activities, respectively. One further precipitinogen with malate dehydrogenase activity was identified for all three life stages.</p>","PeriodicalId":13810,"journal":{"name":"International archives of allergy and applied immunology","volume":"95 2-3","pages":"266-72"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000235440","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13096706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

Interleukin-4 gene expression in human peripheral blood mononuclear cells. 白细胞介素-4基因在人外周血单核细胞中的表达。

International archives of allergy and applied immunology Pub Date : 1991-01-01 DOI: 10.1159/000235443

A Mori, K Yamamoto, M Dohi, M Suko, H Okudaira

引用次数: 11

Influence of mepacrine on the reaction of adoptive cutaneous anaphylaxis. 甲哌辛对过继性皮肤过敏反应的影响。

International archives of allergy and applied immunology Pub Date : 1991-01-01 DOI: 10.1159/000235417

Bashmakov YuK, T V Sidorenko, L A Dugovskaya

引用次数: 0

Effects of the platelet-activating factor antagonist BN 52021 on anti-islet cytotoxicity of mononuclear cells and serum from type 1 (insulin-dependent) diabetic patients. 血小板活化因子拮抗剂bn52021对1型(胰岛素依赖)糖尿病患者单核细胞和血清抗胰岛细胞毒性的影响

International archives of allergy and applied immunology Pub Date : 1991-01-01 DOI: 10.1159/000235472

E Köhler, G Varnai, S Knospe, W Förster, D Michaelis, H Wanka

引用次数: 1

Inhibitors of protein and RNA synthesis block the sensitization of murine peritoneal mast cells. 蛋白质和RNA合成抑制剂阻断小鼠腹膜肥大细胞的致敏作用。

International archives of allergy and applied immunology Pub Date : 1991-01-01 DOI: 10.1159/000235325

J W Coleman

引用次数: 0

The characteristics of antigen define the cellular source and kinetics of histamine-releasing factor induced by human peripheral-blood mononuclear cells. 抗原的特性决定了人外周血单核细胞诱导组胺释放因子的细胞来源和动力学。

International archives of allergy and applied immunology Pub Date : 1991-01-01 DOI: 10.1159/000235349

K J Turner, D Strickland, N P Siemensma, B J Holt

引用次数: 4

Use of antibodies as carriers for T-cell epitopes. 使用抗体作为t细胞表位的载体。

International archives of allergy and applied immunology Pub Date : 1991-01-01 DOI: 10.1159/000235359

T Wyss, C Brander, F Bettens, D Mijic, W J Pichler

{"title":"Use of antibodies as carriers for T-cell epitopes.","authors":"T Wyss, C Brander, F Bettens, D Mijic, W J Pichler","doi":"10.1159/000235359","DOIUrl":"https://doi.org/10.1159/000235359","url":null,"abstract":"T cells recognize proteolytic fragments of proteins (= immunogenic peptides or T-cell epitopes) presented on HLA molecules. Presentation of peptides of exogenous proteins normally occurs on HLA class II structures, while epitopes of endogenous or viral proteins are presented on HLA class I molecules. The type of antigen presenting cell is also of importance for the immune response evolving, since presentation by dendritic cells is capable to trigger a proliferative and cytotoxic immune response [1], while presentation by macrophages favors a proliferative response. In the context of allergic reactions, it is specifically interesting that peptide presentation on aberrantly HLA-DR expressing cells (i.e. thyrocytes in Hashimoto thyroiditis or keratinocytes after interferon treatment) is able to induce clonal anergy, which would be an interesting approach to stop allergic reactions. An insufficient interaction with accessory cell molecules is probably responsible for this failure of a proliferative response [2]. To further evaluate the importance of the type of the antigen presenting cell, we established a system which allows to select the antigen presenting cell. Tetanus toxoid (TT) or an HLA class II binding peptide of TT (residue 830–843, P2) was covalently coupled to anti-CD4, anti-CD8 or anti-CD2 monoclonal antibodies. T cells themselves were chosen as potential antigen presenting cells, as they express HLA-DR after activation and are able to process and present antigens [3], but are unable to capture the antigen. T-cell lines or clones were incubated with these constructs, the proliferative response of TT or P2-spe-cific T-cell clones was evaluated.","PeriodicalId":13810,"journal":{"name":"International archives of allergy and applied immunology","volume":"94 1-4","pages":"187-8"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000235359","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12882755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1