{"title":"The relationship between workplace risk assessments and measures to manage psychosocial risks at work: findings from ESENER.","authors":"David Beck, Morten Wahrendorf, Sabine Sommer, Mariann Rigó, Uwe Lenhardt, Thorsten Lunau","doi":"10.1007/s00420-025-02158-3","DOIUrl":"10.1007/s00420-025-02158-3","url":null,"abstract":"<p><strong>Purpose: </strong>Workplace risk assessment (WRA) is crucial for the management of psychosocial risks at work (PSRM), but some enterprises may also implement PSRM measures without formal WRA, in particular small and micro enterprises. This study analyses the associations between WRA and PRSM, and whether the associations vary by company size.</p><p><strong>Methods: </strong>The data come from the European Survey of Enterprises on New and Emerging Risks (ESENER) collected at the enterprise level in the EU-28 countries in 2014 (n = 40,584) and 2019 (n = 39,711). We distinguish eight measures of PSRM, and assess whether companies conduct a comprehensive WRA that includes psychosocial risks.</p><p><strong>Results: </strong>Many companies reported PSRM measures. The lowest rates were for \"intervention in the case of long working hours\" (2014: 26%, 2019: 32%), while the highest rates were for \"procedures in the case of threats\" (56%, 60%). Enterprises with a comprehensive WRA are more likely to implement measures (even after controlling for company size, industry, sector and country), but some enterprises have implemented PSRM even in the absence of a WRA, especially in 2014 or in smaller companies (5-49 employees). For example, findings suggest that in 2014 40% of the enterprises without a WRA have implemented \"procedures in the case of threats\" (2019: 46%).</p><p><strong>Conclusion: </strong>The findings underline the importance of a WRA that includes psychosocial risks as a means of implementing PSRM measures, but also advocates for a broader perspective that considers measures taken independently of legal occupational safety and health (OSH) standards, especially in small and micro enterprises.</p>","PeriodicalId":13761,"journal":{"name":"International Archives of Occupational and Environmental Health","volume":" ","pages":"695-706"},"PeriodicalIF":2.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12494631/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144753291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reduced lung function among non-smoking workers in the paper industry in Ethiopia: a comparative cross-sectional study.","authors":"Ararso Tafese, Bente E Moen, Abera Kumie, Samson Wakuma Abaya, Wakgari Deressa, Teferi Abegaz, Magne Bråtveit","doi":"10.1007/s00420-025-02163-6","DOIUrl":"10.1007/s00420-025-02163-6","url":null,"abstract":"<p><strong>Purpose: </strong>Exposure to paper dust in the workplace might increase the risk of reduced lung function. This study aims to evaluate the relationship between paper dust exposure and lung function among workers in the paper industry in Ethiopia.</p><p><strong>Methods: </strong>A comparative cross-sectional study assessed lung function in workers exposed to dust in the paper industry and compared them with controls from the water bottling industry. Lung function tests were conducted using a portable spirometer. A job exposure matrix was developed to estimate cumulative exposure to inhalable paper dust. Analysis of covariance was performed to compare mean lung function between exposed and control groups and multivariate linear regression analysis was carried out for workers exposed to paper dust.</p><p><strong>Results: </strong>There was a significant difference in forced expiratory volume in one second (FEV<sub>1</sub>) between the groups. FEV<sub>1</sub> was 2.62 l in the exposed group, compared to 2.97 l in the control group. The multiple linear regression analysis revealed that cumulative paper dust exposure was associated with a reduction in both FEV<sub>1</sub> and forced vital capacity (FVC). Each unit increases in dust exposure (measured in mg year/m<sup>2</sup>) was associated with a 0.010 l decrease in both FEV<sub>1</sub> and FVC in females and a 0.005-liter decrease in males.</p><p><strong>Conclusions: </strong>The findings indicate a significant exposure-response relationship between cumulative paper dust exposure and a decline in lung function with the effect being more pronounced among female workers than among males. Based on these results, we recommend the paper industry to implement effective dust control strategies.</p>","PeriodicalId":13761,"journal":{"name":"International Archives of Occupational and Environmental Health","volume":" ","pages":"721-729"},"PeriodicalIF":2.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12494600/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144952916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
James B Wallace, Peter G Osmotherly, Tim J Gabbett, Wayne Spratford, Phil M Newman
{"title":"Identifying contributory risk factors for neck pain in fast jet aircrew: a prospective cohort study.","authors":"James B Wallace, Peter G Osmotherly, Tim J Gabbett, Wayne Spratford, Phil M Newman","doi":"10.1007/s00420-025-02162-7","DOIUrl":"10.1007/s00420-025-02162-7","url":null,"abstract":"<p><strong>Purpose: </strong>Fast jet aircrew (FJA - aka fighter pilots, fighter aircrew) commonly suffer musculoskeletal complaints, particularly of the neck, which degrades operational capability and workforce health. Establishing injury aetiology is a prerequisite for developing effective preventative interventions. Our objective was to examine the aetiology of neck-related musculoskeletal complaint episodes (NRMCEs) among FJA across a range measures including physical capacity, psycho-social recovery-stress states, workload measures, and strength and conditioning (S&C) participation.</p><p><strong>Methods: </strong>279 Royal Australian Air Force (RAAF) FJA were followed over four 5-month reporting periods. Forty-four baseline measures and 26 weekly measures were analysed for their effect on weekly risk of NRMCEs. Mixed-effects logistic regression was used, potential confounders were adjusted for, and non-linear relationships were examined.</p><p><strong>Results: </strong>320 new NRMCEs were included with mean weekly prevalence of 4.1% (SD 2.3) and mean 5-month reporting period prevalence of 22.4% (range 15.3-28.5%). Previous neck pain, higher worry scores, larger acute flying workloads, more weekly flights, and larger acute and chronic S&C workloads, were factors identified to increase weekly risk of NRMCE. Significant non-linear effects were identified for chronic flying workloads, acute and chronic sleep quality scores, and absolute isometric strength of neck rotation and trunk flexion. Demographics, flying history, anthropometry measures, neck and trunk range of motion, and S&C participation, however, did not affect weekly risk of new NRMCE.</p><p><strong>Conclusion: </strong>These findings provide crucial support for the design of targeted prevention programs for FJA, ensuring they are both effective and efficient, which will in turn optimise operational capability.</p>","PeriodicalId":13761,"journal":{"name":"International Archives of Occupational and Environmental Health","volume":" ","pages":"707-720"},"PeriodicalIF":2.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12494672/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144855200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Biresaw Wassihun, Alemu Michael Waller, Leigh R Tooth
{"title":"Correction: Association between shift/night work and irregular periods and period pain among two cohorts of Australian women 16 years apart: findings from the Australian longitudinal study on women's health.","authors":"Biresaw Wassihun, Alemu Michael Waller, Leigh R Tooth","doi":"10.1007/s00420-025-02156-5","DOIUrl":"10.1007/s00420-025-02156-5","url":null,"abstract":"","PeriodicalId":13761,"journal":{"name":"International Archives of Occupational and Environmental Health","volume":" ","pages":"775-776"},"PeriodicalIF":2.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12494610/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144553464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nicole M Gatto, Marian Ramzy, Cecilia Rocha, Howard N Hodis, Fred Lurmann, Victor W Henderson, Wendy J Mack
{"title":"Air pollution and depression symptoms in middle-aged and older adults in Los Angeles County.","authors":"Nicole M Gatto, Marian Ramzy, Cecilia Rocha, Howard N Hodis, Fred Lurmann, Victor W Henderson, Wendy J Mack","doi":"10.1007/s00420-025-02165-4","DOIUrl":"10.1007/s00420-025-02165-4","url":null,"abstract":"<p><strong>Objective: </strong>Long-term exposure to air pollutants may be harmful to the brain, potentially through inducing oxidative stress or inflammation. Few studies of air pollution and depression have been conducted in the United States where this mental health disorder is prevalent among adults. We investigated associations between ambient air pollutants (O<sub>3</sub>, PM<sub>2.5</sub> and NO<sub>2</sub>) and depression symptoms in middle-aged and older adults (n = 1496) without cardiovascular disease or cognitive impairment in Los Angeles, California.</p><p><strong>Methods: </strong>Air pollution exposures were assigned to residential addresses using a geographic information system with air quality monitoring data. The Center for Epidemiological Studies-Depression scale (CES-D) assessed depression symptoms at study entry. Carotid artery intima-media thickness (CIMT) was obtained as a measure of subclinical atherosclerosis. Linear and Poisson regression models estimated cross-sectional associations between air pollutants and total CES-D score and suspected clinical depression (CES-D score ≥ 16) adjusting for potential confounders and examined effect modification by CIMT.</p><p><strong>Results: </strong>Higher exposure to O<sub>3</sub>, PM<sub>2.5</sub> and NO<sub>2</sub> overall were not cross-sectionally associated with higher CES-D total scores or CES-D score ≥ 16. However, the interaction between CIMT and PM<sub>2.5</sub> was statistically significant (β-interaction term = 1.01, 95% CI = 0.05, 1.97; p-value = 0.03). Adults with CIMT levels ≥ 0.77 mm had higher depression symptom prevalence as PM<sub>2.5</sub> increased (β = 0.04 per 10 µg/m<sup>3</sup>, 95% CI = -0.22, 0.30) while those with CIMT < 0.77 mm had lower prevalence (β = -0.18, 95% CI = -0.41, 0.05).</p><p><strong>Conclusions: </strong>Higher O<sub>3</sub>, PM<sub>2.5</sub> and NO<sub>2</sub> exposures were generally unassociated with depressive symptoms. Additional studies are needed to investigate whether persons with higher subclinical atherosclerosis are more susceptible to possible PM<sub>2.5</sub> effects on mental health.</p>","PeriodicalId":13761,"journal":{"name":"International Archives of Occupational and Environmental Health","volume":" ","pages":"731-741"},"PeriodicalIF":2.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12494606/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144953175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Occupational hazards in veterinary practice: a 15-year review of Türkiye's official ınjury and disease data (2008-2023).","authors":"Ahmet Çabuk","doi":"10.1007/s00420-025-02168-1","DOIUrl":"10.1007/s00420-025-02168-1","url":null,"abstract":"<p><p>PURPOSE: This study aims to examine the trends in occupational accidents and diseases within Türkiye’s veterinary services sector between 2008 and 2023, focusing on sector-specific risks and the effects of national occupational health and safety legislation. METHODS: A descriptive, cross-sectional analysis was conducted using official, publicly available datasets from the Social Security Institution. Incident Rate (IR), Permanent Incapacity Rate (IRp), and Fatality Rate (IRf) were calculated per 100,000 employees. Comparative analyses were performed between pre-law (2008–2012) and post-law (2013–2023) periods using the Mann–Whitney U test. Gender-based analysis was conducted solely for IR due to limited IRp and IRf data. RESULTS: After the implementation of Law No. 6331 in 2012, a statistically significant increase in IR was observed (p = 0.0005), while IRf remained statistically stable. IRp showed a moderate increase (p = 0.0473). Gender-based IR analysis indicated higher rates among female employees in several years. No verified cases of occupational disease were reported for the veterinary sector during the study period. CONCLUSION: Veterinary services in Türkiye exhibit a distinct risk profile, especially concerning ergonomic and psychosocial hazards, which remain statistically underreported. The findings support the development of sector-specific surveillance systems and gender-responsive preventive strategies aligned with international standards.</p>","PeriodicalId":13761,"journal":{"name":"International Archives of Occupational and Environmental Health","volume":" ","pages":"743-755"},"PeriodicalIF":2.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145023281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The role of personal risk factors in the occurrence of the hand-arm vibration syndrome: a pooled analysis of individual data from Italian cross-sectional and cohort studies.","authors":"Massimo Bovenzi, Federico Ronchese, Francesca Larese Filon, Enrico Marchetti, Angelo Tirabasso, Carlotta Massotti, Marco Tarabini","doi":"10.1007/s00420-025-02169-0","DOIUrl":"10.1007/s00420-025-02169-0","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the role of personal risk factors in the occurrence of the vascular, neurological and fibroproliferative disorders of the hand-arm vibration syndrome (HAVS) in workers groups exposed to hand-transmitted vibration (HTV).</p><p><strong>Methods: </strong>HAVS prevalence and incidence data were pooled across a series of cross-sectional studies (total sample: 1272 HTV workers, 579 controls) and prospective cohort studies (total sample: 377 HTV workers, 138 controls) conducted in Central and North-Eastern Italy. The pooled studies included detailed individual-level information about HTV exposure, personal risk factors, medical comorbidities and HAVS disorders. Vibration exposures were evaluated according to the recommendations of ISO standards.</p><p><strong>Results: </strong>The pooled studies revealed dose-response relationships between HTV exposure and the vascular and neurological components of HAVS. Older age, excessive alcohol intake, and comorbid conditions such as metabolic disorders, traumas/surgery to the neck and upper limbs, and disorders of the cervical spine were differentially associated with HAVS outcomes. Higher BMI had a protective effect on vascular disorders. Data modelling showed no significant interactions between HTV exposure and personal risk factors in the occurrence of upper limb disorders.</p><p><strong>Conclusions: </strong>The pooled analysis of epidemiological studies with individualised work, personal, and medical data confirmed that HTV exposure is a primary occupational risk factor for disorders in the fingers and hands of users of vibratory tools. Ageing and some personal factors connected to lifestyles and comorbidities were associated with an increased risk for upper limb disorders in HTV workers. Occupational and personal risk factors tended to contribute independently of each other to adverse outcomes in operators of hand-held vibrating machinery.</p>","PeriodicalId":13761,"journal":{"name":"International Archives of Occupational and Environmental Health","volume":" ","pages":"757-774"},"PeriodicalIF":2.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12494641/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145023232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Occupational health of employees with mental health issues: the role of the psychosocial working conditions and sense of coherence.","authors":"Anja I Lehmann, Georg F Bauer","doi":"10.1007/s00420-025-02154-7","DOIUrl":"10.1007/s00420-025-02154-7","url":null,"abstract":"<p><strong>Background: </strong>The high prevalence of mental health issues (MHI) among employees poses significant societal challenges. However, little is known about factors that influence their ability to remain employed, maintain productivity, and thrive at work.</p><p><strong>Objective: </strong>This study examines differences in occupational health outcomes (burnout, work engagement, and work ability) between employees with and without MHI and the applicability of the Job Demands-Resources model (including job demands, job resources as psychosocial working conditions and sense of coherence (SOC) as a personal resource) among employees with MHI, while particularly controlling for disease-specific factors.</p><p><strong>Methods: </strong>Pooled data from two measurement waves were analyzed, including employees with current MHI (N = 92) and those without MHI (N = 877) from German-speaking countries. Mixed-effects models examined relationships between sociodemographic, disease-specific factors, psychosocial working conditions, SOC, and occupational health outcomes.</p><p><strong>Results: </strong>Employees with MHI showed lower occupational health levels (higher burnout, reduced work ability) than those without. Among employees with MHI, SOC and job resources were significantly associated with all occupational health outcomes, while job demands primarily predicted burnout. Sickness absence correlated negatively with both burnout and work ability. The association between SOC and work ability was stronger for employees with MHI than for those without.</p><p><strong>Conclusions: </strong>Job resources and SOC play a role for occupational health in employees with MHI. Targeted interventions to strengthen these resources should be prioritized.</p>","PeriodicalId":13761,"journal":{"name":"International Archives of Occupational and Environmental Health","volume":" ","pages":"573-585"},"PeriodicalIF":2.4,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12484290/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144325615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association between safety climate, safety participation, safety compliance, and occupational injuries among workers in large-scale building construction projects in Ethiopia.","authors":"Teferi Abegaz, Wakgari Deressa, Bente E Moen","doi":"10.1007/s00420-025-02164-5","DOIUrl":"10.1007/s00420-025-02164-5","url":null,"abstract":"<p><strong>Purpose: </strong>The construction industry is widely acknowledged as one of the most hazardous sectors for workers. This study examined the associations between safety climate and safety behaviour on self-reported injuries in large-scale construction sites in Ethiopia.</p><p><strong>Methods: </strong>A cross-sectional study was conducted from January to May 2023 among 1203 workers from 22 large-scale construction sites. Study participants from each site were selected using a proportional-to-the-size approach. The Nordic Safety Climate Questionnaire (NOSAQ-50) was administered using interviews. Binary logistic regression analysis was performed to identify the relationship between safety climate, safety behaviour, and other factors of self-reported injuries.</p><p><strong>Results: </strong>The prevalence of self-reported injuries in the last twelve months was 35.7% [95% CI (33.0, 38.4)]. Over one-third (35%) of the victims missed more than three workdays due to occupational injuries. Factors affecting self-reported injuries included being a carpenter [AOR = 2.86, 95% CI (1.91-4.28)], being an iron bender [AOR = 1.58, 95% CI (1.02-2.44)], having less than 5 years of work experience [AOR = 1.54, 95% CI (1.18-2.01)], lack of training [AOR = 2.16, 95% CI (1.27-3.72)], low safety climate [AOR = 1.53, 95% CI 1.06-2.21)], low safety participation [AOR = 2.16, 95% CI 1.64-2.86)], and low safety compliance [AOR = 2.32, 95% CI 1.79-3.02)].</p><p><strong>Conclusions: </strong>This study revealed a high magnitude of injuries and identified a relationship between safety climate, safety behaviors, and occupational injuries in the construction industry. Ensuring the work sites' safety climate and improving compliance with safety rules and procedures is essential.</p>","PeriodicalId":13761,"journal":{"name":"International Archives of Occupational and Environmental Health","volume":" ","pages":"685-694"},"PeriodicalIF":2.4,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12484091/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144953143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Massira Ousseni Diawara, Gaoju Pan, Xu Yang, Mohammed Alqudaimi, Mahamadou Fofana, Solim Essomandan Clémence Bafei, Di Wu, Hein Min Tun, Qianqi Liu, Mingzhi Zhang, Yankai Xia
{"title":"Thyrotoxic effects of organophosphate insecticides in adults: a bibliometric and meta-analysis.","authors":"Massira Ousseni Diawara, Gaoju Pan, Xu Yang, Mohammed Alqudaimi, Mahamadou Fofana, Solim Essomandan Clémence Bafei, Di Wu, Hein Min Tun, Qianqi Liu, Mingzhi Zhang, Yankai Xia","doi":"10.1007/s00420-025-02159-2","DOIUrl":"10.1007/s00420-025-02159-2","url":null,"abstract":"<p><strong>Objective: </strong>Organophosphate insecticides (OPIs) are widely used worldwide, raising growing concerns over their potential thyrotoxic effects. Despite mounting evidence, inconsistencies persist regarding their impact on thyroid hormone (TH) regulation in humans. This study aimed to clarify the relationship between OPI exposure and TH levels in adults, addressing a critical gap in environmental health research.</p><p><strong>Methods: </strong>A systematic literature search was conducted on Pubmed, Cochrane Library, Web of Science, and Google Scholar before 15th May 2025. After extraction, a bibliometric analysis was applied to synthetize the associations between OPIs and TH in adults; while a meta-analysis was performed to summarize epidemiological investigations with THs, including thyroid-stimulating hormone (TSH), total and free triiodothyronine (T3 and FT3), and total and free thyroxine (T4 and FT4).</p><p><strong>Results: </strong>From an initial pool of 852 articles, thirteen studies met the inclusion criteria for bibliometric analysis. Most were published between 1999 and 2024, with a peak in 2010, and originated primarily from the USA and Spain. Of these, seven studies, encompassing data from 6308 adults were included in the meta-analysis and grouped by five THs. The meta-analysis revealed significant negative associations in serum levels of T3 [β = - 0.02 (95% CI - 0.03, - 0.01)], and FT3 [β = - 0.02 (95% CI - 0.03, - 0.01)].</p><p><strong>Conclusion: </strong>These findings highlight the potential endocrine-disrupting effects of OPI exposure in adults, particularly on the hypothalamic-pituitary-thyroid axis (HPT), and emphasize the need for continued investigation into the public health implications of such environmental exposures.</p>","PeriodicalId":13761,"journal":{"name":"International Archives of Occupational and Environmental Health","volume":" ","pages":"631-647"},"PeriodicalIF":2.4,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144730301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}