INTERNATIONAL JOURNAL OF APPLIED PHARMACEUTICAL SCIENCES AND RESEARCH最新文献_第8页

Rp-Hplc Method for Estimation of Metoprolol Succinate and Olmesartan Medoxomil in Pharmaceutical Formulation with forced Degradation Studies 反相高效液相色谱法测定制剂中琥珀酸美托洛尔和奥美沙坦美多索米的含量及强制降解研究

INTERNATIONAL JOURNAL OF APPLIED PHARMACEUTICAL SCIENCES AND RESEARCH Pub Date : 2019-08-22 DOI: 10.21477/IJAPSR.4.3.1

T. Kumar, Samata Samantaray, D. Sankar

{"title":"Rp-Hplc Method for Estimation of Metoprolol Succinate and Olmesartan Medoxomil in Pharmaceutical Formulation with forced Degradation Studies","authors":"T. Kumar, Samata Samantaray, D. Sankar","doi":"10.21477/IJAPSR.4.3.1","DOIUrl":"https://doi.org/10.21477/IJAPSR.4.3.1","url":null,"abstract":"A simple, specific, accurate, and precise RP-HPLC method was developed and validated for the simultaneous estimation of Metoprolol Succinate and Olmesartan Medoxomil in pharmaceutical formulation with forced degradation studies. The method was developed using Enable C 18G column (250 ×4.6 mm, 5 μm) with mobile phase consisting of methanol and water (pH adjusted to 3.5 with orthophosphoric acid in the ratio of 80: 20 % v/v with a flow rate of 1 mL/min. The UV detection was carried out at 240 nm. The retention time for Metoprolol Succinate and Olmesartan Medoxomil were found to be 3.986 and 6.092 min, respectively. The proposed method was validated for linearity, range, accuracy, precision, robustness, LOD, and LOQ. Linearity was observed over a concentration range 4-40 μg/mL for Metoprolol Succinate (r2 = 0.9999) and 5-60 μg/ml for Olmesartan Medoxomil (r2 = 0.9999). The % RSD for Intraday and Interday precision was found to be 0.57 and 0.68 for Metoprolol Succinate and 0.52 and 0.41 for Olmesartan Medoxomil. The LOD and LOQ were found to be 0.1143 μg/mL and 0.3565 μg/mL for Metoprolol Succinate and LOD and LOQ were found to be 0.0563 and 0.1782 μg/mL for Olmesartan Medoxomil respectively.","PeriodicalId":13749,"journal":{"name":"INTERNATIONAL JOURNAL OF APPLIED PHARMACEUTICAL SCIENCES AND RESEARCH","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84742781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

PREPARATION AND EVALUATION OF NEEM (AZADIRACHTA INDICA) EXTRACT MICROBEADS USING HYDROGEL SYSTEM FOR WOUND HEALING 水凝胶法制备印楝提取物微球用于伤口愈合的研究

INTERNATIONAL JOURNAL OF APPLIED PHARMACEUTICAL SCIENCES AND RESEARCH Pub Date : 2019-07-10 DOI: 10.31069/JAPSR.V2I2.3

R. Asija, V. Nair, A. Gupta

{"title":"PREPARATION AND EVALUATION OF NEEM (AZADIRACHTA INDICA) EXTRACT MICROBEADS USING HYDROGEL SYSTEM FOR WOUND HEALING","authors":"R. Asija, V. Nair, A. Gupta","doi":"10.31069/JAPSR.V2I2.3","DOIUrl":"https://doi.org/10.31069/JAPSR.V2I2.3","url":null,"abstract":"Introduction: Neem (Azadirachta indica, Meliaceae) is being used as an antimicrobial agent in traditional systems of medicines since ancient times. Neem is also applied on wounds in the form of aqueous extracts of various parts of the plant but is associated with problems of stability on long term storage. Objective: In the present work, the aim was to incorporate Neem (Azadirachta indica) extract in hydrogel system and prepare microbeads for application on wounds. Material and methods: The microbeads were prepared by mixing of drug and polymers to cause poly ionic complexation. The formulation was evaluated for various pharmaceutical parameters such as Solubility, Drug Release, Water Holding Capacity, % Drug Entrapped, Bead Diameter Measurement and Antimicrobial study. Result and Discussion: The evaluation of the optimized batch showed % drug entrapped to be 5.61 %, drug release of 65.688% in phosphate buffer pH 8 within 5 hrs and water uptake of 80% which were similar to the solutions obtained by the design expert DX7 Statease software. This suggested that the optimization model is validated. The microbeads of the optimized batch had a diameter of approximately 80 μm. Conclusion: Polymeric encapsulation in the form of beads allowed controlled delivery as well as enhanced stability of Azadirachtin. It provides a cost-effective antimicrobial therapy.","PeriodicalId":13749,"journal":{"name":"INTERNATIONAL JOURNAL OF APPLIED PHARMACEUTICAL SCIENCES AND RESEARCH","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80204970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

CURIOUS CASE OF DRUG RESISTANT MALARIA AND ARTEMISININ COMPOUNDS IN THE MODERN ERA 现代疟疾和青蒿素化合物耐药的奇怪案例

INTERNATIONAL JOURNAL OF APPLIED PHARMACEUTICAL SCIENCES AND RESEARCH Pub Date : 2019-07-08 DOI: 10.31069/JAPSR.V2I2.1

Mudasir Maqbool, Amin Mohamad Dar, Shafiqa Rasool, Misba Khan

{"title":"CURIOUS CASE OF DRUG RESISTANT MALARIA AND ARTEMISININ COMPOUNDS IN THE MODERN ERA","authors":"Mudasir Maqbool, Amin Mohamad Dar, Shafiqa Rasool, Misba Khan","doi":"10.31069/JAPSR.V2I2.1","DOIUrl":"https://doi.org/10.31069/JAPSR.V2I2.1","url":null,"abstract":"Malaria is caused by Plasmodium parasite, transmitted by the bite of infective female Anopheles mosquito. The four species causing human infections are P falciparum, P vivax, P malariae and P ovale. P falciparum causes the majority of infections and is main culprit for most severe disease and mortality. Whereas P. vivax and P. ovale form resting stages in the liver (hypnozoites), that once reactivated, can lead to a clinical relapse many months after the initial event. The effective treatment is now compounded by the spread of drug resistant strains of the parasite. As a result, traditional alkaloid drugs such as chloroquine and quinine are now largely ineffective. The spread of parasite resistance has led the World Health Organization (WHO) to predict that without new antimalarial drug intervention, the number of cases of malaria will definitely increase. The growing menace of drug resistance has greatly complicated the treatment for malaria. Whereas chloroquine and sulfadoxine/pyrimethamine could once cure most infections, this is no longer true and requires examination of alternative regimens for the treatment of malaria. Artemisinin-based combinations are now widely accepted as the best treatments for uncomplicated falciparum malaria. Such combination treatments are rapid and reliably effective. The efficacy of the treatment is determined by the drug partnering the artemisinin derivative and, for artesunate-mefloquine, artemether-lumefantrine, and dihydroartemisinin-piperaquine, this usually exceeds 95%. This paper unfolds resistance to various conventional antimalarials and brief outline about artemisinin derivatives.","PeriodicalId":13749,"journal":{"name":"INTERNATIONAL JOURNAL OF APPLIED PHARMACEUTICAL SCIENCES AND RESEARCH","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83501104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

AN EXHAUSTIVE REVIEW ON HERBS USED IN THE MANAGEMENT OF DIABETES MELLITUS TYPE 2 对草药在2型糖尿病治疗中的应用进行了详尽的综述

INTERNATIONAL JOURNAL OF APPLIED PHARMACEUTICAL SCIENCES AND RESEARCH Pub Date : 2019-07-08 DOI: 10.31069/JAPSR.V2I2.2

Salman Mau, Shakir Saleem, Vishwadeepak Kimothi, V. Joshi, Sanjay Singh

{"title":"AN EXHAUSTIVE REVIEW ON HERBS USED IN THE MANAGEMENT OF DIABETES MELLITUS TYPE 2","authors":"Salman Mau, Shakir Saleem, Vishwadeepak Kimothi, V. Joshi, Sanjay Singh","doi":"10.31069/JAPSR.V2I2.2","DOIUrl":"https://doi.org/10.31069/JAPSR.V2I2.2","url":null,"abstract":"Diabetes mellitus is one of the most common metabolic disorders associated with disturbed hormonal secretion. Diabetes is characterized by high blood glucose levels over a prolonged period of time. High sugar levels are due to abnormal metabolism of carbohydrates and lipids which is caused by absolute or relative insulin deficiency. Herbal medicines have been the highly esteemed source of medicine throughout the human history. Herbs are becoming more popular today because of their least side effects, holistic beliefs, easy availability and low cost. Individual herbal products and formulations are gaining popularity because of their quality manufacturing using modern analytical techniques and standardized raw materials. Herbal drugs are widely used for the treatment of diabetes worldwide in various dosage forms. India has a long list of native herbal drugs with scientifically proven blood sugar lowering properties. The seeds of Nigella sativa, Olea europaea, fruits of Aegle marmelos, Momordica charantia, Coccinia indica, Nigella sativa,Gymnema sylvestre leaves,whole plant of Pterocarpus marsupium, Syzygium cumini fruits, Swertia punicea, Urtica dioica, gum of Ferula assa-foetida and seeds of Trigonella foenum graecum were discussed along with their reported mechanisms of action. In this review paper an attempt has been made to give an overview of certain Indian plants which have shown their anti-diabetic activity in various pre-clinical studies.","PeriodicalId":13749,"journal":{"name":"INTERNATIONAL JOURNAL OF APPLIED PHARMACEUTICAL SCIENCES AND RESEARCH","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86182710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

HPLC METHOD DEVELOPMENT AND VALIDATION FOR AZITHRO-MYCIN IN ORAL SUSPENSION 口服混悬液中阿奇霉素HPLC测定方法的建立与验证

INTERNATIONAL JOURNAL OF APPLIED PHARMACEUTICAL SCIENCES AND RESEARCH Pub Date : 2019-04-01 DOI: 10.31069/JAPSR.V2I1.2

Alok Pratap Singh, Iti Chauhan, Snigdha Bhardwaj, P. Gaur, S Sadish Kumar, Jayendra J

{"title":"HPLC METHOD DEVELOPMENT AND VALIDATION FOR AZITHRO-MYCIN IN ORAL SUSPENSION","authors":"Alok Pratap Singh, Iti Chauhan, Snigdha Bhardwaj, P. Gaur, S Sadish Kumar, Jayendra J","doi":"10.31069/JAPSR.V2I1.2","DOIUrl":"https://doi.org/10.31069/JAPSR.V2I1.2","url":null,"abstract":"Introduction: Azithro-mycin a semi-synthetic, azalide congener of erythro-mycin indicated in the treatment of respiratory tract infections. Various methods available for determination of Azithro-mycin, but HPLC are most versatile one. Objective: The present study is based on the development and validation of a rapid, simple high performance liquid chromatography (HPLC) method equipped with UV detector for quantitative analysis of Azithro-mycin (AZN) in suspension. Material and methods: The Method was performed by using Hypersil BDS-C18 (250 mm × 4.6 mm i.d.) column MS-II, with an isocratic mobile phase of methanol, acetonitrile and phosphate buffer pH 8 (60:30:10; v/v) with run time 15 minutes. The determinations were performed at a flow rate of 1.0ml/min, and UV detector set at 212 nm. Result and Discussion: The method was found to be specific with relative standard deviation (RSD) less than 2.09%. The method showed accuracy with RSD less than 1.34% and precision in repeatability with RSD less than 1.42%. The method was found to be linear over a wide range of concentration from 1.0 to 50.0 μg/mL (R2 = .995). Limit of detection and limit of quantification were found to be 14.40 ng/mL and 43.66 ng/mL respectively. Conclusion: It was advantageous to use UV detector over other methods employing electrochemical, photodiode array etc. as the detector, because of cheap and easy availability. The developed method fulfilled all validation parameters as per ICH and can be successfully applied to quantify percent drug content in marketed oral Azithro-mycin suspension.","PeriodicalId":13749,"journal":{"name":"INTERNATIONAL JOURNAL OF APPLIED PHARMACEUTICAL SCIENCES AND RESEARCH","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74343233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

ORAL DELIVERY OF ZOLMITRIPTAN LOADED FAST DISINTEGRATING FILM: FORMULATION DEVELOPMENT, STATISTICAL OPTIMIZATION, IN-VITRO AND IN-VIVO EVALUATION 口服佐米曲坦快速崩解膜:配方开发、统计优化、体内体外评价

INTERNATIONAL JOURNAL OF APPLIED PHARMACEUTICAL SCIENCES AND RESEARCH Pub Date : 2019-04-01 DOI: 10.31069/JAPSR.V2I1.3

Iti Chauhan, Mohammad Yasir, Madhu Verma

{"title":"ORAL DELIVERY OF ZOLMITRIPTAN LOADED FAST DISINTEGRATING FILM: FORMULATION DEVELOPMENT, STATISTICAL OPTIMIZATION, IN-VITRO AND IN-VIVO EVALUATION","authors":"Iti Chauhan, Mohammad Yasir, Madhu Verma","doi":"10.31069/JAPSR.V2I1.3","DOIUrl":"https://doi.org/10.31069/JAPSR.V2I1.3","url":null,"abstract":"Introduction: Fast dissolving film technology has been developed out as a alternative drug delivery system that gives an exception advantage for taking medications. Objective: The aim of this study was to formulate and evaluate the Zolmitriptan loaded fast disintegrating oral film by solvent casting method. Material and methods: A preliminary study was conducted to select a suitable film forming polymer and plasticiser concentration.The formulation was optimized with the help of 22 factorial designs in which polymer and plasticizer concentration at two levels was taken as independent factors and disintegration time, tensile strength and % elongation were taken as dependent factors. The optimized formulation OP1 was subjected to stability study as per the ICH guidelines at 40 ± 0.50C / 75 ± 5% RH for six months. In vivo studies were conducted on Wister albino rats and concentration of drug in blood was analysed by HPLC technique. Various pharmacokinetic parameters for OP1 were determined and compared with reference formulation (drug sol.). Result and Discussion: For optimized formulation various parameters were found to be in acceptable range and it was stable under specified conditions. The value of AUC0–t (ng h/ml), AUC0–∞ (ng h/ml) of the OP1 was found to be 723.91± 84.21, 770.90 ± 104.32, respectively, for the drug sol 468.56 ± 79.36, 500.37 ± 95.43 respectively. Relative bioavailability of OP1 was 1.55 time than that of drug sol. Conclusion: The formulation not only increases the bioavailability of drug but also produce the quick action for the migraine patients. ","PeriodicalId":13749,"journal":{"name":"INTERNATIONAL JOURNAL OF APPLIED PHARMACEUTICAL SCIENCES AND RESEARCH","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86777867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

COSMETICS AND THEIR ASSOCIATED ADVERSE EFFECTS: A REVIEW 化妆品及其相关不良反应综述

INTERNATIONAL JOURNAL OF APPLIED PHARMACEUTICAL SCIENCES AND RESEARCH Pub Date : 2019-04-01 DOI: 10.31069/JAPSR.V2I1.1

A. Khan, Mohammad Niyaz Alam

{"title":"COSMETICS AND THEIR ASSOCIATED ADVERSE EFFECTS: A REVIEW","authors":"A. Khan, Mohammad Niyaz Alam","doi":"10.31069/JAPSR.V2I1.1","DOIUrl":"https://doi.org/10.31069/JAPSR.V2I1.1","url":null,"abstract":"The word ‘cosmetics’ is taken from a Greek word “kosmeticos” which means to adorn. Since early days materials used for beautification or improvement of appearance comes under the category of cosmetics. People want to look beautiful and the concept of cosmetics is as old as mankind and civilization. The urge to beautify one’s own body and look beautiful has been an urge in the human race since the tribal days. Assorted beauty products such as skincare products, hair products, fragrances, oral hygiene, and nail products, which may contain toxic chemicals that can be harmful to health are used especially by women. Since long time cosmetics have been known to enhance the appearance of the human body. In a society obsessed with beauty, people are lured to fake their appearance as a cure for their insecurities. The estimated value of cosmetic industry today is around 20 billion dollar globally. As a consumer, we are constantly attracted to using beauty and personal care products. But these products, which are supposed to make us feel healthy and look beautiful, have a deep dark side. Various toxic ingredients and hazardous chemicals used in cosmetics are incorporated in beyond acceptable limits. These chemicals may cause serious ill effects on skin and may also enter the skin and other organs causing carcinogenicity. Cosmetics have not only seeped into the fashion world but are also playing a prominent role in one’s day-to-day life. Thus, it becomes a necessity to make people aware of the various harmful effects of cosmetics and chemicals used in cosmetics.","PeriodicalId":13749,"journal":{"name":"INTERNATIONAL JOURNAL OF APPLIED PHARMACEUTICAL SCIENCES AND RESEARCH","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89806979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 45

Removal of Chrysoidine Y from water by Graphene-based Nanocomposite Derivatives with Magnetic Chitosa Nanocomposite 磁性壳聚糖纳米复合材料石墨烯基纳米复合衍生物去除水中的黄玉Y

INTERNATIONAL JOURNAL OF APPLIED PHARMACEUTICAL SCIENCES AND RESEARCH Pub Date : 2019-03-08 DOI: 10.21477/IJAPSR.4.2.2

F. A. Shammala, B. Chiswell

{"title":"Removal of Chrysoidine Y from water by Graphene-based Nanocomposite Derivatives with Magnetic Chitosa Nanocomposite","authors":"F. A. Shammala, B. Chiswell","doi":"10.21477/IJAPSR.4.2.2","DOIUrl":"https://doi.org/10.21477/IJAPSR.4.2.2","url":null,"abstract":"This article describes a novel and efficient MCTS/GO nanocomposite for the accumulation and removal of a hazardous azo dye (Chrysoidine Y) from its aqueous solutions. Magnetic Chitosan /graphene oxide (MCTS/GO) nanocomposite adsorbent was prepared by wet-spinning technique, was used as accumulation and removal of Chrysoidine Y from aqueous solution. The structure and morphology of MCTS/GO nanocomposites were investigated using transmission electron microscope (TEM) and Fourier transform infrared (FTIR) spectroscopy were carried out on the MCTS/GO before the Chrysoidine Y (CY) accumulation experiments. The adsorption kinetics and isotherm studies were conducted under different conditions (pH = 3-7 and CY concentration = 100-400 mg/L) to examine the accumultion efficiency of the MCTS/GO towards CY in aqueous solution. The kinetics data of the adsorption process were analyzed using different kinetic models in order to investigate the adsorption behavior of CY on MCTS/GO. The results showed that the maximum adsorption capacity of the MCTS/GO nanocomposites towards CY can achieve up to ~700 mg/g for the adsorption at 300 mg/L CY. Kinetic data of adsorption process were found to fit pseudo-second order model as compared with pseudo-first-order model. The intraparticle diffusion model suggested that the adsorption process of MCTS/GO towards CY was dominated by the external mass transfer of CY molecules to the surface of MCTS/GO.","PeriodicalId":13749,"journal":{"name":"INTERNATIONAL JOURNAL OF APPLIED PHARMACEUTICAL SCIENCES AND RESEARCH","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80551966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Early Miscarriage: Morphological Data Useful to Clinical and Nosographic Classification 早期流产:形态学数据对临床和医院分类有用

INTERNATIONAL JOURNAL OF APPLIED PHARMACEUTICAL SCIENCES AND RESEARCH Pub Date : 2019-03-08 DOI: 10.21477/IJAPSR.4.2.1

S. Erra, C. Merlo

引用次数: 0

AN IN-DEPTH OF A PHARMACIST IN PRESCRIBING 药剂师对处方的深入研究

INTERNATIONAL JOURNAL OF APPLIED PHARMACEUTICAL SCIENCES AND RESEARCH Pub Date : 2019-01-15 DOI: 10.31069/JAPSR.V1I4.2

Abdul Kader Mohiuddin

引用次数: 3