International Journal of Clinical Rheumatology最新文献_第6页

Think out of the box! Pediatric onset adult Sarcoidosis in a young child presenting as Pyrexia of unknown origin 跳出框框思考!儿童发病成人结节病在一个年幼的孩子表现为不明原因的发热

International Journal of Clinical Rheumatology Pub Date : 2020-01-01 DOI: 10.37532/1758-4272.2020.15(5).131-132

Supriya S Shinde, Jagadish Chinnappa, B. Shenoy, Tripti Kaur Sagar Bhattad

引用次数: 0

Immune-mediated clinical manifestations associated with cocainelevamisole use- A literature review 免疫介导的临床表现与可卡因乙酰米索的使用-文献综述

International Journal of Clinical Rheumatology Pub Date : 2020-01-01 DOI: 10.37532/1758-4272.2020.15(6).155-163

L. J. Miguel, Lopez Marta

引用次数: 0

Frequency and outcomes of venous thrombus embolism in hospitalized patients with Behçet's disease 住院behaperet病患者静脉血栓栓塞的发生频率和预后

International Journal of Clinical Rheumatology Pub Date : 2020-01-01 DOI: 10.37532/1758-4272.2020.15(3).

Christopher G. Gibson, W. Swindell, Benjamin Strickl, Stephanie Rosenberg

{"title":"Frequency and outcomes of venous thrombus embolism in hospitalized patients with Behçet's disease","authors":"Christopher G. Gibson, W. Swindell, Benjamin Strickl, Stephanie Rosenberg","doi":"10.37532/1758-4272.2020.15(3).","DOIUrl":"https://doi.org/10.37532/1758-4272.2020.15(3).","url":null,"abstract":"Background: Behcet’s Disease (BD) is a multisystem vasculitis characterized by skin-mucosa lesions, ocular, musculoskeletal, gastrointestinal, neurologic, and major vessel involvement. The objective of this present study was to investigate BD in the inpatient setting and the associated risk of contracting venous thrombus embolism. Methods: We utilized the Healthcare Cost and Utilization Project’s National Inpatient Sample (NIS) database. The NIS is the largest inpatient care database in the United States, containing demographic and clinical information from approximately 8 million hospital stays from about 1000 hospitals sampled to approximate a 20% stratified sample of U.S. community hospitals. The 2016 NIS sample utilized ICD-10-CM/PCS diagnostic and procedure codes. Results: The 2016 NIS analysis was performed using 7,135,090 discharge summaries, of which 622 were \"case\" summaries associated with the ICD-10 code for Behcet's disease (M352). Case discharge summaries were also associated with a slightly longer hospital stay 5.6 days compared to 4.7 days. The percentage of VTE-related ICD codes was 2.8 times higher in case compared to control summaries (P = 4.4e-35). Overall, approximately 1 in 5 case summaries (19.45%) was linked to a VTErelated ICD code, compared to only 6.85% of control summaries. These trends were consistent in analyses performed for each sex separately. Case-male summaries were more frequently associated with VTE-related codes (28.19%) compared to case-female summaries (15.7%). Conclusion: Our study illustrates the association of BD and VTE-related ICD events.","PeriodicalId":13740,"journal":{"name":"International Journal of Clinical Rheumatology","volume":"45 1","pages":"67"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85928982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

2D speckle tracking detects early left ventricular dysfunction in patients with sarcoidosis 二维斑点跟踪检测结节病患者早期左心室功能障碍

International Journal of Clinical Rheumatology Pub Date : 2020-01-01 DOI: 10.37532/1758-4272.2020.15(6).188-192

C. Chourabi, Houaida Mahfoudhi, S. Chenik, S. Sayhi, R. Dhahri, Azza Redissi, A. Haggui, N. Hajlaoui, D. Lahidheb, A. Faida, N. Abdelhafidh, Bassem Louzir Wafa Fehri

{"title":"2D speckle tracking detects early left ventricular dysfunction in patients with sarcoidosis","authors":"C. Chourabi, Houaida Mahfoudhi, S. Chenik, S. Sayhi, R. Dhahri, Azza Redissi, A. Haggui, N. Hajlaoui, D. Lahidheb, A. Faida, N. Abdelhafidh, Bassem Louzir Wafa Fehri","doi":"10.37532/1758-4272.2020.15(6).188-192","DOIUrl":"https://doi.org/10.37532/1758-4272.2020.15(6).188-192","url":null,"abstract":"Background: Sarcoidosis is a multisystemic granulomatous disease of unknown origin. Cardiac involvement is known to have a poor prognosis; sudden death may be its initial presentation. Conventional echocardiography remains insufficient for the detection of subclinical myocardial dysfunction. In our study we aimed to assess the prevalence of subclinical cardiac dysfunction using left ventricle global longitudinal strain. Results: we performed a cross-sectional study, 55 patients with established diagnosis of systemic sarcoidosis and 50 healthy age- and sex-matched controls underwent a transthoracic echocardiography, 9 patients were excluded, and 46 patients were included in the study. Left ventricular dimensions and ejection fraction were similar between the two groups (66% Vs 67%). Left ventricle global longitudinal strain was significantly lower in patients with sarcoidosis (-17.15 +/-3 Vs -22.4+/-2, p: 0.001). Conclusion: left ventricle global longitudinal strain may be an advanced indicator of cardiac sarcoidosis that needs to be studied further.","PeriodicalId":13740,"journal":{"name":"International Journal of Clinical Rheumatology","volume":"15 1","pages":"188"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88419265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Coventry fast track pathway for managing giant cell arteritis 治疗巨细胞动脉炎的考文垂快速通道

International Journal of Clinical Rheumatology Pub Date : 2020-01-01 DOI: 10.37532/1758-4272.2019.15(2).21-25

S. Dubey, J. Pinnell, C. Mehta

{"title":"Coventry fast track pathway for managing giant cell arteritis","authors":"S. Dubey, J. Pinnell, C. Mehta","doi":"10.37532/1758-4272.2019.15(2).21-25","DOIUrl":"https://doi.org/10.37532/1758-4272.2019.15(2).21-25","url":null,"abstract":"Giant cell arteritis (GCA) is the commonest form of vasculitis seen in United Kingdom (UK). It usually presents with new onset headaches, scalp tenderness, jaw claudication or visual symptoms – acute visual loss is a catastrophic presentation and complication of untreated GCA. Hence, it is treated as a medical emergency. Most units have a protocol for assessing these patients and treating these patients promptly – usually this involves the general practitioner GP) starting steroids and sending the patient to secondary care for further evaluation. Recent utility of vascular Doppler ultrasound (US) has allowed many units to develop a fast track pathway for assessing and managing these patients. Coventry established its walk-in fast track pathway which included clinical assessment with rheumatology and/or ophthalmology along with US in 2013. Patients were normally seen within a few hours of referral and the pathway is unique in not needing GPs to start steroids in advance of their assessment in secondary care. This article describes the rationale for the way the pathway was designed and also describes the results of the initial pilot phase of this pathway.","PeriodicalId":13740,"journal":{"name":"International Journal of Clinical Rheumatology","volume":"13 1","pages":"21"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85033295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Comorbidities in rheumatoid arthritis: the RBSMR study 类风湿性关节炎的合并症:RBSMR研究

International Journal of Clinical Rheumatology Pub Date : 2020-01-01 DOI: 10.37532/1758-4272.2020.15(1).10-14

F. Haddani, A. Guich, T. Youssoufi, E. Boudhar, R. Abouqal, L. Achemlal, F. Allali, R. Bahiri, Bouchti Ei, Maghraoui Ei, I. Ghozlani, T. Harzy, I. Hmamouchi, L. Ichchou, O. Mkinsi, H. NiamaneRHassikou

{"title":"Comorbidities in rheumatoid arthritis: the RBSMR study","authors":"F. Haddani, A. Guich, T. Youssoufi, E. Boudhar, R. Abouqal, L. Achemlal, F. Allali, R. Bahiri, Bouchti Ei, Maghraoui Ei, I. Ghozlani, T. Harzy, I. Hmamouchi, L. Ichchou, O. Mkinsi, H. NiamaneRHassikou","doi":"10.37532/1758-4272.2020.15(1).10-14","DOIUrl":"https://doi.org/10.37532/1758-4272.2020.15(1).10-14","url":null,"abstract":"Objective: The objectives of this study are as follows: to define the profile of comorbidities during rheumatoid arthritis; deduce the predictive factors for their occurrence and their impact on the activity and severity of the disease. Methods: 225 patients followed for rheumatoid arthritis, meeting the ACR/EULAR 2010 criteria under biotherapy, included in the national biotherapy register. We proceeded to group patients into 2 groups: patients with and without co-morbidities in order to study the prevalence of co-morbidities, their predictors of occurrence and the correlation between these co-morbidities, the activity and the severity of the disease. Results: The average age was 51.94 years ± 11.36 (20-80) with a female predominance of 87.6%, the average duration of evolution was 737.8 weeks with an average diagnostic delay of 719.5 weeks. The average SAR 28 (crp) was 3.5 ± 1.39. Corticosteroid therapy was noted in 94.2%, with an average cumulative dose of 37,360 mg. The average body mass index was 27.56 kg/m2. At least comorbidity was present in 67.1% of patients, the most common of which was osteoporosis (22.7%). The presence of comorbidity was associated with a longer duration of development (p=0.001) and positive rheumatoid serology (p=0.049). Likewise, they were more frequent among women without a profession. Conclusion: Our study confirms the high prevalence of comorbidities during rheumatoid arthritis, hence the importance of screening them for better management.","PeriodicalId":13740,"journal":{"name":"International Journal of Clinical Rheumatology","volume":"33 1","pages":"10"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76021310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Ultrasound-guided caudal epidural steroid injection for sciatica: simplicity, efficacy and safety 超声引导下尾侧硬膜外类固醇注射治疗坐骨神经痛:简单、有效、安全

International Journal of Clinical Rheumatology Pub Date : 2020-01-01 DOI: 10.37532/1758-4272.2021.16(1).005

Charles Sougue Yves Maugars

{"title":"Ultrasound-guided caudal epidural steroid injection for sciatica: simplicity, efficacy and safety","authors":"Charles Sougue Yves Maugars","doi":"10.37532/1758-4272.2021.16(1).005","DOIUrl":"https://doi.org/10.37532/1758-4272.2021.16(1).005","url":null,"abstract":"The possibility of precisely locating the sacral hiatus, which is greatly facilitated by echography, has rekindled interest in epidural infiltrations via this route, particularly as rare but serious complications have been reported for other epidural injection techniques, such as those using the foraminal route or particulate products. Products injected via the sacral hiatus have been shown to ascend efficiently to the lumbar spine. In recalcitrant sciatica, epidural injections of corticosteroids via the three principal routes (sacral hiatus, interlaminar, foraminal) have similar mean efficacies. Injection via the sacral hiatus, or caudal injection, has similar complications to interlaminar and foraminal injections, but these complications appear to be much rarer by this route, and avoidable if several indispensable technical precautions are applied: five-step asepsis, echographic control to check for the absence of pilonidal cysts, avoidance of canal catheterization, avoidance of the injection of air, allergenic products, anesthetic products or particulate products, and slow injection. The sacral hiatus route can be used to ensure epidural infiltration without a risk of dural leak, in patients on antiplatelet treatment, even after surgery. Further studies are required to increase the efficacy and safety of this technique and to evaluate the benefits of injecting therapeutic agents other than corticosteroids via this route.","PeriodicalId":13740,"journal":{"name":"International Journal of Clinical Rheumatology","volume":"31 1","pages":"005"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90403888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Elevated alkaline phosphatase: The initial laboratory abnormality in an atypical presentation of Takayasu Arteritis 碱性磷酸酶升高:高须动脉炎不典型表现的初始实验室异常

International Journal of Clinical Rheumatology Pub Date : 2020-01-01 DOI: 10.37532/1758-4272.2019.15(2).33-36

A. Chawla, Kathlyn Camargo Macias, S. Vuyyuru, Bernard Gros Lance Feller

{"title":"Elevated alkaline phosphatase: The initial laboratory abnormality in an atypical presentation of Takayasu Arteritis","authors":"A. Chawla, Kathlyn Camargo Macias, S. Vuyyuru, Bernard Gros Lance Feller","doi":"10.37532/1758-4272.2019.15(2).33-36","DOIUrl":"https://doi.org/10.37532/1758-4272.2019.15(2).33-36","url":null,"abstract":"Background: Takayasu Arteritis rarely presents in men over the age of 40, particularly with an isolated elevated alkaline phosphatase level. Case presentation: A 46-year-old Hispanic man with no prior history of rheumatic disease presented with acute onset of chest pain radiating to his left upper extremity. His cardiovascular workup was unremarkable with exception of an elevated alkaline phosphatase level (ALP), approximately three times the upper limit of normal. Over a short period of time, his ALP up trended and clinical exam revealed BP discrepancies between his upper extremities, vascular bruits and a profound asymmetry in brachial and radial pulses. MRA-Chest confirmed mural thickening and luminal narrowing of the proximal left subclavian artery and the diagnosis of Takayasu Arteritis was made. Upon receiving glucocorticoids and corticosteroid sparing immunosuppressive agents, his clinical manifestations (chest pain, left arm claudication) had markedly improved while ALP decreased. Conclusion: In addition to clinical exam and imaging studies, laboratory studies (such as ALP) may aid in support of a diagnosis of large vessel vasculitis. In the literature, this has been described primarily in those with giant cell arteritis/polymyalgia rheumatica. In patients with an elevated ALP in the appropriate clinical setting, consideration should be given to the diagnosis of Takayasu Arteritis. This may aid in early initiation of appropriate therapy.","PeriodicalId":13740,"journal":{"name":"International Journal of Clinical Rheumatology","volume":"73 1","pages":"33"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79683701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ergonomics in musculoskeletal ultrasonography 肌肉骨骼超声的人体工程学

International Journal of Clinical Rheumatology Pub Date : 2020-01-01 DOI: 10.37532/1758-4272.2020.15(4).109-113

Sabido-Sauri Ricardo, Ventura-Rios Lucio Hern, ez-Diaz Cristina

{"title":"Ergonomics in musculoskeletal ultrasonography","authors":"Sabido-Sauri Ricardo, Ventura-Rios Lucio Hern, ez-Diaz Cristina","doi":"10.37532/1758-4272.2020.15(4).109-113","DOIUrl":"https://doi.org/10.37532/1758-4272.2020.15(4).109-113","url":null,"abstract":"Background: Ergonomics is the science responsible for understanding the interactions between human beings and other elements in a system. In medical disciplines such as ultrasonography, Work-Related Musculoskeletal Diseases (WRMD) has a high prevalence. Shoulder, neck and wrists are the most frequent sites of injuries. The importance of the WRMD stands out because it generates significant economic and labor disabilities. Objective: The most studied musculoskeletal lesions in professionals are related to obstetric, vascular, abdominal, and cardiac ultrasonographer practice. Thus, a search focused on musculoskeletal ultrasonography was carried out. Methods: This manuscript is a summary of a systematic review conducted through databases (EBSCO, Pubmed, ClinicalKey) using articles and guides between 1995 and 2016; restricted to articles published in English and Spanish, and all related to musculoskeletal ultrasound practice. Results: There are few reports related to the impact of WRMD in professional ultrasonographers despite the increased use of musculoskeletal ultrasound since the '80s, but neither the existence nor an ergonomic plan to apply to those professionals are published. Conclusions: WRMD are increasing related to practice; the need of a wide review of the main risk factors, production mechanisms and injury prevention measures must be carried out soon.","PeriodicalId":13740,"journal":{"name":"International Journal of Clinical Rheumatology","volume":"84 1","pages":"109"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83483947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Obesity-induced AA amyloidosis: A diagnosis of exclusion 肥胖引起的AA淀粉样变:一种排除性诊断

International Journal of Clinical Rheumatology Pub Date : 2020-01-01 DOI: 10.37532/1758-4272.2019.15(2).26-32

A. Brunger, H. Nienhuis, R. V. Rheenen, M. Korte, J. Bijzet, Reinold O.B. Gans Bouke P.C. Hazenberg

{"title":"Obesity-induced AA amyloidosis: A diagnosis of exclusion","authors":"A. Brunger, H. Nienhuis, R. V. Rheenen, M. Korte, J. Bijzet, Reinold O.B. Gans Bouke P.C. Hazenberg","doi":"10.37532/1758-4272.2019.15(2).26-32","DOIUrl":"https://doi.org/10.37532/1758-4272.2019.15(2).26-32","url":null,"abstract":"A 47-year-old woman with morbid obesity (body mass index: 41 kg/m2) and a history of hypertension, pulmonary embolism and successfully treated gout (one year ago) presented with nephrotic syndrome (15 g/24 h) and loss of kidney function (endogenous creatinine clearance 27 ml/min/1.73 m2). A kidney biopsy revealed AA amyloid. An extensive investigation was performed to detect an underlying inflammatory disease process by testing blood and urine, imaging and genetic testing for autoinflammatory diseases. Serum levels of C-reactive protein (CRP) and serum amyloid A protein (SAA) were continuously elevated. Serum amyloid P component (SAP)- scintigraphy showed intense uptake in a massively enlarged liver and in the spleen. This extensive investigation did not reveal an underlying inflammatory process. Her gout became asymptomatic almost immediately after start of treatment. Therefore, we concluded that morbid obesity was the most probable cause of her AA amyloidosis. Treatment with colchicine and prednisolone did not substantially reduce the SAA and CRP levels. Also, treatment with anakinra (interleukin-1 receptor antagonist) and tocilizumab (interleukin-6 receptor antagonist) failed. The downhill course of the disease progressed to complete renal failure within three years and dialysis was started. This case indicates that the long-standing low-grade inflammation seen in morbid obesity may be a potential cause of systemic AA amyloidosis and may be difficult to treat. However, it is essentially a diagnosis of exclusion, since known underlying inflammatory conditions should be excluded first.","PeriodicalId":13740,"journal":{"name":"International Journal of Clinical Rheumatology","volume":"22 1","pages":"26"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72651248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3