International Angiology最新文献

{"title":"Characteristics and percutaneous transluminal angioplasty treatment outcomes of superior vena cava obstruction in patients undergoing hemodialysis.","authors":"Ran Tian, Zhengli Tan, Zhengya Yu","doi":"10.23736/S0392-9590.24.05347-1","DOIUrl":"10.23736/S0392-9590.24.05347-1","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to investigate the clinical outcomes of percutaneous transluminal angioplasty (PTA) in patients undergoing hemodialysis with different types of superior vena cava obstruction (SVCO) lesions.</p><p><strong>Methods: </strong>This retrospective observational study recruited patients undergoing hemodialysis with SVCO and analyzed the clinical characteristics of SVCO. Patency rates were collected for patients treated with PTA and were assessed using the t-test, U-test, log-rank test and survival analyses such as the Kaplan-Meier method.</p><p><strong>Results: </strong>A total of 49 patients undergoing hemodialysis with SVCO were classified as type I (N.=17), type II (N.=7), type III (N.=15) and type IV (N.=10). All patients had a history of catheter placement. There were 14 cases of SVCO-related catheter dysfunction, and PTA was performed in 35 patients with a technical success rate of 77.14% (27/35). Failures were observed exclusively in eight patients with type III or IV lesions. The median follow-up was 15 (1.5-58) months, with 6- and 12-month post-PTA primary patency rates of 51.9% and 14.4%, respectively. The primary assisted patency rates were 70.2% and 55.2%, and the secondary patency rates were 92.6% and 78.0%, requiring 2.68 PTAs per patient per year to maintain them. Type I-II lesions demonstrated significantly higher primary patency and primary assisted patency rates than type III-IV lesions (P=0.007 and P=0.002).</p><p><strong>Conclusions: </strong>Percutaneous transluminal angioplasty may be used to treat type I or II SVCO, achieving high technical success and patency rates. Patients undergoing hemodialysis with SVCO may have a condition related more to catheter placement than to arteriovenous fistula.</p>","PeriodicalId":13709,"journal":{"name":"International Angiology","volume":"43 6","pages":"621-628"},"PeriodicalIF":1.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of arterial hypertension in patients with peripheral arterial disease.","authors":"Pavel Poredoš, Dimitri P Mikhailidis, Kosmas I Paraskevas, Aleš Blinc, Pier L Antignani, Agata Stanek, Armando Mansilha, Matija Cevc","doi":"10.23736/S0392-9590.24.05242-8","DOIUrl":"10.23736/S0392-9590.24.05242-8","url":null,"abstract":"<p><p>Hypertension is a major risk factor for peripheral arterial atherosclerotic disease (PAD). Hypertension deteriorates arterial wall function and the morphology of all layers of arteries. Endothelial cell injury enhances permeability and promotes migration of cholesterol and monocytes into the vessel wall. Increased blood pressure (BP) through hyperplasia of smooth muscle cells initiates remodeling of the arterial wall that increases peripheral resistance. Further, hypertension, particularly in patients with dyslipidemia, provokes atherosclerosis in different vascular territories, including the lower legs. Guidelines recommend treatment of hypertension in patients with PAD to reach the target BP of <130/80 mmHg. However, systolic BP (SBP) <120 mmHg may worsen oxygen delivery to the diseased leg and is related to a higher rate of cardiovascular (CV) events. Therefore, there is a J-shape relationship between SBP and the rate of primary outcomes. Any class of antihypertensive drugs, including beta-blockers, can be used for the treatment of hypertension in patients with PAD. Angiotensin converting enzyme (ACE) inhibitors may have some additional benefit over other antihypertensive drugs including improvement of perfusion of the diseased leg and are recommended even in patients with critical limb ischemia. In conclusion: hypertensive patients with PAD are at increased risk for CV events and treatment of raised BP is indicated, but SBP <120 mmHg and DBP <70 mmHg may contribute to adverse limb outcomes and other CV events. Consequently, PAD patients may require a different BP target than those without PAD.</p>","PeriodicalId":13709,"journal":{"name":"International Angiology","volume":" ","pages":"541-547"},"PeriodicalIF":1.5,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142667851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interventions for the treatment of recurrent varicose vein disease arising from the saphenofemoral junction or the great saphenous vein: a systematic review and meta-analysis.","authors":"Alkis Bontinis, Vangelis Bontinis, Georgios Koudounas, Argirios Giannopoulos, Christos Karkos, Dimitrios Virvilis, Angeliki Chorti, Kiriakos Ktenidis","doi":"10.23736/S0392-9590.24.05323-9","DOIUrl":"10.23736/S0392-9590.24.05323-9","url":null,"abstract":"<p><strong>Introduction: </strong>We investigated the safety and feasibility of the available interventions in the treatment of recurrent varicose vein disease.</p><p><strong>Evidence acquisition: </strong>A systematic search on Medline, Scopus, and Web of Science for articles published by August 2024 was performed. Primary endpoints included duplex ultrasonography (DUS)-identified recurrence and clinical recurrence.</p><p><strong>Evidence synthesis: </strong>Twenty-eight studies, eleven describing endovenous thermal ablation (EVTA), four ultrasound-guided foam sclerotherapy (UGFS), and thirteen surgery (high ligation with or without stripping) encompassing 2228 limbs, were included. The overall DUS-detected recurrence estimate was 11.84% (95% CI: 7.15-17.40). EVTA displayed the lowest recurrence of 4.27% (95% CI: 0.37-10.75), followed by UGFS 11.19% (95% CI: 6.80-16.42) and surgery 23.27% (95% CI: 15.35-32.19). Statistically significant differences were observed between surgery and both EVTA (P<0.01) and UGFS (P=0.01). The overall clinical recurrence estimate was 24.91% (95% CI: 10.40-42.96) with EVTA portraying the lowest clinical recurrence of 2.37% (95% CI: 0.00-16.81), followed by surgery 31.08% (95% CI: 14.43-50.63). Subgroup analysis identified statistically significant differences between EVTA and surgery (P=0.01). Whereas non-statistically significant differences were identified between the included interventions regarding paresthesia and deep vein thrombosis (DVT), surgery exhibited higher wound infection estimates compared to EVTA of 0.00% (95% CI: 0.00-0.80) versus 4.34% (95% CI: 2.21-7.02, P<0.01). The pooled hematoma and lymphatic complication estimates for surgery were 5.04% (95% CI: 0.50-12.87) and 5.71% (95% CI: 2.91-9.22) respectively.</p><p><strong>Conclusions: </strong>This review demonstrated the superior efficacy of EVTA over surgery in treating recurrent varicose vein disease corroborating its use as the preferred treatment, when feasible. Additionally, UGFS displayed comparable outcomes to EVTA. The notable recurrence estimates associated with surgery call into question its suitability within this context.</p>","PeriodicalId":13709,"journal":{"name":"International Angiology","volume":" ","pages":"485-496"},"PeriodicalIF":1.5,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142667844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prescription versus over-the-counter venotonics: HPLC-DAD and static digestive model simulation comparison.","authors":"Robert Novotny, Matyas Orsak, Jaromir Lachman, Kotikova Zora, Barbora Novotna, Jaroslav Hlubocky, Jan Pitha, Libor Janousek","doi":"10.23736/S0392-9590.24.05291-X","DOIUrl":"https://doi.org/10.23736/S0392-9590.24.05291-X","url":null,"abstract":"<p><strong>Background: </strong>Venotonics are a class of therapeutically active molecules that have vaso-protective effects. They are used to alleviate venous diseases and disorders, particularly venous insufficiency. We compared the composition of prescription versus over-the-counter (OTC) venotonics using high-performance liquid chromatography with UV detection (HPLC-DAD) and simulating their digestion using a static digestive model.</p><p><strong>Methods: </strong>From each drug, five tablets were weighed. A homogenate was prepared, and 25 mg of crushed homogenized tablets were weighed into 25 ml volumetric flasks. Dissolved in MeOH and added two drops of saturated NaOH solution. The samples were filtered into vials (Teflon, 0.45 μm) and used for analysis. An Ultimate 3000 HPLC system (Thermo Fisher Scientific, Waltham, MA, USA) consisting of a quaternization pump, autosampler, column thermostat and DAD (UV/VIS detector) was used. The composition of the mobile phase proceeded in a linear gradient from 30% methanol and 70% phosphoric acid (0.15%) in water at time t=0 min. to 80% methanol and 20% phosphoric acid (0.15%) at time t=15 min., at a constant mobile phase flow rate of 1.2 mL/min. Detection was performed using a DAD detector in the 190-450 nm wavelength range. The content of monitored flavonoids was calculated from peaks at a wavelength of 277 nm, in which both flavonoids have their absorption maxima. The static digestive model was used to simulate the digestive phase from the oral cavity to the corresponding intestinal phase.</p><p><strong>Results: </strong>The content of diosmin and hesperidin (mg per table) for a prescription drug: Detralex: 480 mg, 26 mg. The content of diosmin and hesperidin (mg per tablet) for OTC drugs: Venostop: 502 mg, 48 mg, Diosminol: 520 mg, 50 mg, Devenal: 496 mg, 49 mg, Diohes: 493 mg, 46 mg. Digestion did not affect the solubility of all tested drugs. The active substances could not be determined in the non-alkalized sample. After alkalization, part of the insoluble matter was visibly dissolved and converted to a yellow flavonoid complex. Neither diosmin nor hesperidin could be identified afterwards.</p><p><strong>Conclusions: </strong>Our experimental results show that the contents of both listed active substances, diosmin and hesperidin, met the declared amounts in all tested medicaments. Digestion simulation showed identical behaviour in prescription and OTC venotonics. The active substances could not be determined in the non-alkalized sample. Digestion did not affect the solubility of the tested drugs.</p>","PeriodicalId":13709,"journal":{"name":"International Angiology","volume":"43 5","pages":"469-475"},"PeriodicalIF":1.5,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142768585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mini-skin longitudinal incision versus traditional longitudinal incision for carotid endarterectomy in patients with carotid artery stenosis: a systematic review and meta-analysis.","authors":"Filipa Jácome, José Oliveira-Pinto, Ana Dionísio, Andreia Coelho, José F Ramos, Armando Mansilha","doi":"10.23736/S0392-9590.24.05300-8","DOIUrl":"10.23736/S0392-9590.24.05300-8","url":null,"abstract":"<p><strong>Introduction: </strong>Carotid endarterectomy (CEA) remains the gold standard intervention for stroke prevention in patients with carotid artery stenosis but the surgical technique continues evolving with research being conducted on minimally invasive alternatives. Mini-skin incision CEA has emerged as a more aesthetically appealing and less painful alternative to the traditional technique with a potential impact on main procedural events. We aimed to provide a review of the literature and to compare the mini-skin incision with the traditional approach.</p><p><strong>Evidence acquisition: </strong>A systematic review was conducted following the PRISMA guidelines. Databases PubMed and Scopus were last searched on 20^th July 2023. Procedural stroke, cranial/cervical nerves injury and mortality were defined as primary outcomes and length of hospitalization and minor complications as secondary outcomes. We included manuscripts comparing mini-skin with traditional incision CEA, and reporting our pre-established outcomes. The quality of studies was evaluated using the Newcastle-Ottawa Scale. We assessed heterogeneity and performed a meta-analysis for quantitative analysis when appropriate.</p><p><strong>Evidence synthesis: </strong>Five studies comprising a total of 2912 CEA procedures (2738 patients; 75.7% males) were included in both the qualitative and quantitative analysis. Compared with the traditional CEA, mini-skin incision led to a statistically significant decrease in periprocedural cranial/cervical nerve injury (OR 0.30, 95% CI 0.21, 0.43; P<0.01). Length of hospital stay and minor complications were significantly decreased in the mini-skin incision group (P<0.05). Concerning 30-day stroke rate and mortality no differences were attained.</p><p><strong>Conclusions: </strong>Our results suggest that mini-skin incision CEA might be a safer approach, with the potential to significantly decrease the perioperative morbidity. Further studies are needed to confirm these preliminary findings and to reinforce the role of mini-skin incision CEA as a promising, less invasive alternative in the treatment armamentarium of carotid artery stenosis.</p>","PeriodicalId":13709,"journal":{"name":"International Angiology","volume":"43 5","pages":"533-540"},"PeriodicalIF":1.5,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142768582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Organization of angiology in countries with associate societies of International Union of Angiology.","authors":"Pavel Poredos, Pier L Antignani, Peter Poredos, Armando Mansilha","doi":"10.23736/S0392-9590.24.05336-7","DOIUrl":"https://doi.org/10.23736/S0392-9590.24.05336-7","url":null,"abstract":"<p><p>Angiology is a multidisciplinary medical discipline, consequently in some countries multidisciplinary vascular centres were organized, which provide comprehensive management of patients with different vascular diseases. However, the organization of the care for vascular patients differs between the countries. Therefore, we aimed to check the organization of angiology (vascular surgery and vascular medicine) in countries-associate members of IUA and to stimulate the development of multidisciplinary vascular centres. The questionnaire was sent to 60 countries- associate members of IUA, and 35 societies from 30 countries responded. The responses showed that in most countries vascular patients are treated by vascular surgeons. Vascular surgeons and radiologists are also main providers of peripheral arterial diagnostics and invasive treatment. In most countries vascular medicine is marginalized. With the exception of some west European countries multidisciplinary vascular centres are rare and facilities for management of vascular patients insufficient. National societies expect from IUA more educational activities and creating consensus documents. Therefore, IUA should promote the foundation of vascular centres and provide systemic education in angiology.</p>","PeriodicalId":13709,"journal":{"name":"International Angiology","volume":"43 5","pages":"548-552"},"PeriodicalIF":1.5,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142768584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current evidence on the effectiveness and safety of oral anticoagulants in superficial venous thrombosis: a systematic review and meta-analysis.","authors":"Vito A Damay, Ignatius Ivan, Marc Vuylsteke","doi":"10.23736/S0392-9590.24.05309-4","DOIUrl":"10.23736/S0392-9590.24.05309-4","url":null,"abstract":"<p><strong>Introduction: </strong>Previous studies suggest fondaparinux as an effective regimen for superficial venous thrombosis (SVT), but the inconvenience of prolonged parenteral injections has prompted investigations into oral anticoagulants (OACs). This study aims to evaluate the current evidence on the effectiveness and safety of OACs in the treatment of SVT.</p><p><strong>Evidence acquisition: </strong>Following the PRISMA 2020 guidelines, we conducted a systematic review and meta-analysis registered in PROSPERO (CRD42024535625). A comprehensive literature search was performed across multiple databases up to April 2024. Studies were included if they involved adult patients diagnosed with SVT, treated with OACs, and reported relevant efficacy and safety outcomes. Both randomized controlled trials (RCTs) and observational studies were considered. Data extraction and risk of bias assessments were independently performed by two authors.</p><p><strong>Evidence synthesis: </strong>The search identified 1531 studies, with six studies (three RCTs and three prospective cohort studies) meeting inclusion criteria. Meta-analysis for Rivaroxaban-treated group showed DVT occurrence was 1.30% (95% CI 0.17-3.07%), SVT extension was 0.32% (95% CI: 0.00-1.58%), SVT recurrence was 0.75% (95% CI: 0.00-3.30%), clinically relevant non-major bleeding was 1.95% (95% CI: 0.46-4.11%), minor bleeding was 5.68% (95% CI: 3.02-9.01%). These estimates were for patients treated with rivaroxaban 10-20 mg once daily over 42 days to 37 months. No major bleeding was reported with rivaroxaban 10 mg once daily.</p><p><strong>Conclusions: </strong>This systematic review and meta-analysis demonstrate that OACs, especially rivaroxaban, are effective and safe for the treatment of SVT. They offer a convenient alternative to parenteral anticoagulants, potentially improving patient compliance and outcomes. However, further large-scale studies are warranted to confirm these findings.</p>","PeriodicalId":13709,"journal":{"name":"International Angiology","volume":" ","pages":"497-506"},"PeriodicalIF":1.5,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142568387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of light compression on chronic venous disease, edema and comfort in women during pregnancy and postpartum period: a prospective randomized study.","authors":"Aleksandra Frydrych-Szymonik, Katarzyna Ochałek, Agnieszka Jankowicz-Szymańska, Zbigniew Szyguła","doi":"10.23736/S0392-9590.24.05208-8","DOIUrl":"10.23736/S0392-9590.24.05208-8","url":null,"abstract":"<p><strong>Background: </strong>Lower limb edema associated with venous disorders is an increasingly common problem in pregnant women. The study aimed to assess the use of compression class 1 (ccl1=18-21 mmHg) in lower limb edema and CVD prevention in pregnant and postpartum women.</p><p><strong>Methods: </strong>51 pregnant women (second trimester) were randomly recruited into either a study group CG with compression ccl1 or a control group NCG, both with physical activity (PA) recommendation. The assessment concerned venous system condition, limb size, and compression comfort. Edema was diagnosed as ≥10% measurement increase.</p><p><strong>Results: </strong>Venous reflux (8/22 CG, 1/16 NCG) and an onset of CVD (6/22 CG, 1/16 NCG) were diagnosed in the first measurement. After postpartum, a significant reduction of the great saphenous vein (GSV) diameter in the proximal part of the left lower limb in CG (P=0.014) and expansion of the small saphenous vein (SSV) in the proximal part of the left lower limb in NCG (P=0.028) were observed. An analysis of the limb sizes in the second measurement revealed a significant increase of all circumferences and volumes in the NCG, and of lower leg volumes in the CG. Edema was diagnosed in five women in the NCG in the second measurement. Consequently, compression was recommended for the new group (NCG+C), and a significant edema reduction (P=0.026) occurred in the third measurement.</p><p><strong>Conclusions: </strong>Compression ccl1 reduces the risk of edema, venous insufficiency, and improves women's quality of life during pregnancy and postpartum.</p>","PeriodicalId":13709,"journal":{"name":"International Angiology","volume":" ","pages":"476-484"},"PeriodicalIF":1.5,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142568407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Atherosclerotic cardiovascular disease risk based on SCORE algorithms and reclassification based on preclinical atherosclerotic plaques.","authors":"Andrew N Nicolaides, Andrie G Panayiotou, Maura B Griffin, Theodosis Tyllis, Efthyvoulos Kyriacou, Costantinos Avraamides, Dawn Bond, Niki Georgiou, Despo Ierodiakonou, Christiana A Demetriou, Richard M Martin","doi":"10.23736/S0392-9590.24.05248-9","DOIUrl":"https://doi.org/10.23736/S0392-9590.24.05248-9","url":null,"abstract":"<p><strong>Background: </strong>The aim of this study was to determine the efficacy of the number of carotid and common femoral bifurcations with plaque (NBP) detected by ultrasound in reclassifying atherosclerotic cardiovascular disease (ASCVD) risk obtained from SCORE algorithms. Data from the cohort of 1000 individuals free from ASCVD in the Cyprus Epidemiological Study on Atherosclerosis was used.</p><p><strong>Methods: </strong>In each predicted ASCVD risk class (low, moderate, high) based on SCORE algorithms and baseline data, the observed 10-year risk of subgroups according to the NBP was used to reclassify participants.</p><p><strong>Results: </strong>There were 222 ASCVD events during a mean follow-up of 15.2±4.9 years. In each predicted risk class, the observed 10-year ASCVD event risk increased progressively in the subgroups across the presence of 1, 2, 3 and 4 bifurcations with plaque (P<0.001); Hazard Ratios (crude and adjusted for conventional risk factors) also increased progressively (P<0.001). There was a correct down classification in 152 and correct up classification in 99 participants. Total correct reclassification improvement was in 251 (25.1%).</p><p><strong>Conclusions: </strong>The results demonstrate that the NBP which is easy to detect is an independent predictor of ASCVD events and can be used to reclassify individuals into a different risk class by improving on the predicted SCORE risk.</p>","PeriodicalId":13709,"journal":{"name":"International Angiology","volume":"43 5","pages":"519-532"},"PeriodicalIF":1.5,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142768519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of hemodynamic suppression on cognitive function in patients after carotid artery stenting.","authors":"Weidong Fan, Kun Liu, Xingyou Guo, Tuo Zhang, Ming Li, Tong Qiao","doi":"10.23736/S0392-9590.24.05318-5","DOIUrl":"https://doi.org/10.23736/S0392-9590.24.05318-5","url":null,"abstract":"<p><strong>Background: </strong>This study examines the impact of carotid artery stenting (CAS) on cognitive function in stroke patients, particularly in relation to hemodynamic depression (HD).</p><p><strong>Methods: </strong>Patients undergoing CAS between January 1, 2019 and June 1, 2023 were included in our study. Depending on whether hemodynamic depression happened, they were separated into two groups: HD and non-HD. Prior to surgery, one month, three months, six months, and a year following surgery, Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment Scale (MoCA), and cognitive function scores were compared.</p><p><strong>Results: </strong>130 patients were included in the study, with an HD incidence rate of 51.54%. The comparison of MMSE and MoCA scores revealed that the HD group showed declining cognitive function post-surgery (P<0.05). Specifically, the MMSE and MoCA scores were significantly lower in the HD group compared to the non-HD group at 3, 6, and 12 months after CAS (P<0.05). Additionally, attention, computation, and memory were significantly lower in the HD group at these time points (P<0.05). The non-HD group demonstrated improvement in MMSE and MoCA scores compared to preoperative levels at 6- and 12-months post-surgery (P<0.05).</p><p><strong>Conclusions: </strong>Following CAS, patients' cognitive ability would briefly drop before returning to baseline and improving even more. Clinical focus should be given to HD prevention because its presence would exacerbate the cognitive function impairment and lengthen the recovery period.</p>","PeriodicalId":13709,"journal":{"name":"International Angiology","volume":"43 5","pages":"507-518"},"PeriodicalIF":1.5,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142768521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}