Infection Control and Hospital Epidemiology最新文献

{"title":"Association between air sampling for viral respiratory pathogens and acute respiratory tract infection cases in the emergency department.","authors":"Meggie Griffin, Helena Ikenberry, Joshua Gauger, Nicholas Kuehnel, Amy L Ellis, Ari N Machtinger, David H O'Connor, Shelby L O'Connor, Daniel Shirley, Michael S Pulia","doi":"10.1017/ice.2026.10538","DOIUrl":"https://doi.org/10.1017/ice.2026.10538","url":null,"abstract":"<p><p>The emergency department (ED) is a common site for respiratory viral surveillance, but air sampling has not been thoroughly explored in this setting. In this study, we observed a significant association between COVID-19, influenza A, and RSV detection via air sampling in an ED waiting room and clinical viral testing.</p>","PeriodicalId":13663,"journal":{"name":"Infection Control and Hospital Epidemiology","volume":" ","pages":"1-3"},"PeriodicalIF":2.6,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149109274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>Candidozyma auris</i> in the United States: insights from the National Association of Long-Term Hospitals Network.","authors":"Kim Tran, Mckenzi King, Nidhi Undevia, Lahari Thotapalli, Hannakate Lichota, Lisa Duffner, Alison Peterson, Rachel Medernach, Ronda Cochran, Mary Carl Froilan, Aleksandra Kozicka, Mary K Hayden, Sarah E Sansom","doi":"10.1017/ice.2026.10548","DOIUrl":"https://doi.org/10.1017/ice.2026.10548","url":null,"abstract":"<p><strong>Objective: </strong>Understand current prevention practices used for <i>Candidozyma auris</i> and identify target areas for improvement.</p><p><strong>Design: </strong>Electronic survey.</p><p><strong>Setting: </strong>Long-term acute care hospitals (LTACHs).</p><p><strong>Participants: </strong>National Association of Long-Term Hospitals (NALTH) network facilities located in the United States.</p><p><strong>Methods: </strong>REDCap survey distributed by email to 56 facilities in the NALTH network exploring knowledge and perceptions related to <i>C. auris</i> screening methods, prevention practices, barriers to prevention, and tools needed to improve containment.</p><p><strong>Results: </strong>Among 33 responses from 56 LTACHs, 23 (70%) had ever identified at least one case of <i>C. auris</i> infection or colonization. Eighteen (54%) reported identifying cases of <i>C. auris</i> within the past three months and nine (27%) had experienced suspected within-facility transmission. All facilities employed multimodal approaches for <i>C. auris</i> infection prevention. The most frequently reported barriers to effective <i>C. auris</i> prevention included lack of communication between healthcare facilities, inadequate training and education for frontline staff, and lack of compliance with personal protective equipment. The most impactful interventions anticipated to support future <i>C. auris</i> containment included improved communication between facilities at the time of patient transfer and standardized protocols for <i>C. auris</i> decolonization and surveillance.</p><p><strong>Conclusions: </strong>Most LTACHs within the NALTH network reported firsthand experience with <i>C. auris</i>. Universally, facilities employed multimodal evidence-based infection prevention and control strategies targeted against <i>C. auris</i>. Future strategies anticipated to improve containment included improving interfacility communication of <i>C. auris</i> colonization status, development of effective decolonization protocols, and standardization of surveillance practices.</p>","PeriodicalId":13663,"journal":{"name":"Infection Control and Hospital Epidemiology","volume":" ","pages":"1-6"},"PeriodicalIF":2.6,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149109276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Novel antibiotic stewardship metrics and the quality of antibiotic prescribing for lower respiratory and urinary tract infection across 24 VA hospitals.","authors":"Shungo Imai, Daniel J Livorsi, Thomas Wright, James Merchant, Hyunkeun Cho, Bruce Alexander, Michihiko Goto","doi":"10.1017/ice.2026.10562","DOIUrl":"https://doi.org/10.1017/ice.2026.10562","url":null,"abstract":"<p><strong>Introduction: </strong>Some inpatient antibiotic use metrics have important limitations, including the absence of patient-level risk adjustment. To address this limitation, we previously developed two risk-standardized ratios (RSRs), one based on days of therapy (RSR-DOT) and the other on days of antibiotic spectrum coverage (RSR-DASC). Here, we evaluated the construct validity of these metrics by examining whether hospital performance was associated with the quality of antibiotic selection and duration in patients with either lower respiratory tract infections (LRIs) or urinary tract infections (UTIs).</p><p><strong>Methods: </strong>Using Veterans Health Administration data from October 2020 through September 2021, we calculated RSR-DOT and RSR-DASC for 121 acute-care hospitals and selected 24 hospitals with relatively low or high values. At each hospital, a blinded infectious diseases physician reviewed 10 admissions each for LRI and UTI. Antibiotic selection at day 3 and total antibiotic duration were adjudicated and summarized as a 6-category ordinal composite outcome. Associations between RSR metrics and antibiotic-prescribing quality were evaluated using ordinal logistic regression; model-fit and bootstrap analyses compared RSR-DOT and RSR-DASC.</p><p><strong>Results: </strong>We reviewed 479 admissions (239 LRI and 240 UTI). In LRI, lower RSR-DASC tended to be associated with a higher quality of antibiotic use (coefficient, 2.906 [<i>P</i> = .053]), whereas RSR-DOT was not (1.418 [<i>P</i> = .374]). In UTI, neither metric was associated with the quality of antibiotic therapy. Model-fit and bootstrap analyses consistently favor RSR-DASC over RSR-DOT for LRI.</p><p><strong>Conclusions: </strong>RSR-DASC may capture antibiotic-prescribing quality more closely than RSR-DOT for LRI, but not for UTI, potentially supporting the value of spectrum-informed benchmarking metrics.</p>","PeriodicalId":13663,"journal":{"name":"Infection Control and Hospital Epidemiology","volume":" ","pages":"1-7"},"PeriodicalIF":2.6,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149108758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Distinct individual and community-level drivers of extended-spectrum beta-lactamase-producing Enterobacterales urinary tract infections.","authors":"Julia Tellerman, Sanjukta Bandyopadhyay, Hsioa Che Looi, Christopher Myers, Jenna Dietz, Ghinwa Dumyati, Brenda L Tesini","doi":"10.1017/ice.2026.10516","DOIUrl":"10.1017/ice.2026.10516","url":null,"abstract":"<p><strong>Objective: </strong>Compare characteristics of community-associated (CA) versus healthcare-associated (HCA) extended-spectrum beta-lactamase-producing Enterobacterales (ESBL-E) urinary tract infection (UTI) cases and assess associations between ESBL-E UTI prevalence and census-tract social vulnerability.</p><p><strong>Design: </strong>Retrospective cohort study.</p><p><strong>Setting: </strong>Monroe County, NY, January 2020-December 2023.</p><p><strong>Patients: </strong>Population surveillance of first urinary ESBL-E isolate among county residents.</p><p><strong>Methods: </strong>ESBL-E, defined as resistance to ≥1 third-generation cephalosporin, was identified from inpatient and outpatient urinary specimens. Demographic, clinical, and healthcare exposure data were abstracted; cases were classified as CA or HCA using standardized definitions. Addresses were geocoded to census tracts and linked to CDC Social Vulnerability Index (SVI) scores. Characteristics were compared using χ² and Wilcoxon tests. Generalized linear models assessed associations between SVI themes and ESBL-E prevalence by epidemiologic classification.</p><p><strong>Results: </strong>Of 3,100 ESBL-E UTI cases, 1,621 (52.3%) were CA and 1,468 (47.4%) HCA. CA cases were younger (median 56 vs 71.5 years), more often female (89.5% vs 68.4%), and less medically complex than HCA cases. HCA prevalence increased with SVI score, while CA prevalence remained stable across SVI levels. The HCA association was mainly driven by SVI Theme 2 (household composition/disability; P = .0011).</p><p><strong>Conclusions: </strong>CA and HCA ESBL-E UTIs exhibit distinct epidemiology. No association was observed between SVI and CA ESBL-E UTI prevalence. HCA prevalence increased with social vulnerability, largely driven by SVI Theme 2, potentially reflecting healthcare exposure and medical complexity. Factors driving CA ESBL-E differ, and ESBL-E reduction efforts should consider broader structural and community factors beyond those captured by the SVI.</p>","PeriodicalId":13663,"journal":{"name":"Infection Control and Hospital Epidemiology","volume":" ","pages":"1016-1022"},"PeriodicalIF":2.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148678366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trends in population attributable risk of <i>Clostridioides difficile</i> infection associated with common outpatient antibiotics in Ontario, Canada, 2017-2024.","authors":"Michelle K Wong, Nick Daneman, Bradley J Langford, Valerie Leung, Kevin L Schwartz, Kevin A Brown","doi":"10.1017/ice.2026.10560","DOIUrl":"https://doi.org/10.1017/ice.2026.10560","url":null,"abstract":"<p><p>We evaluated changes in population attributable risk of \"4C\" antibiotics for community-associated <i>Clostridioides difficile</i> infection in Ontario (2017-2024). Contributions from clindamycin, cephalosporins, and fluoroquinolones declined, whereas amoxicillin-clavulanate increased and became the leading contributor by 2022, highlighting a potential emerging target for outpatient antimicrobial stewardship.</p>","PeriodicalId":13663,"journal":{"name":"Infection Control and Hospital Epidemiology","volume":" ","pages":"1-4"},"PeriodicalIF":2.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149108790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Facilitators and barriers for implementing infection prevention interventions in long-term care: a scoping review.","authors":"Ambra Miagostovich, Ina Willemsen, Thera Habben Jansen, Emely de Vet","doi":"10.1017/ice.2026.10534","DOIUrl":"https://doi.org/10.1017/ice.2026.10534","url":null,"abstract":"<p><strong>Introduction: </strong>Infection prevention and control (IPC) is essential to reduce healthcare-associated infections in long-term care facilities (LTCFs). Its implementation faces unique challenges and is less studied than in acute care. This scoping review mapped barriers and facilitators to IPC implementation in LTCFs.</p><p><strong>Methods: </strong>Standardized procedures for scoping reviews were followed (eg, PRISMA-ScR). PubMed, Web of Science, CINAHL and PsycINFO were searched (2008-2025). Out of 965 articles, 21 studies were included. Data were charted and mapped to the (sub)domains of the Consolidated Framework for Implementation Research (CFIR).</p><p><strong>Results: </strong>Studies covered nursing homes, pediatric care, and disability care facilities in North America (n = 11), Europe (n = 8), Australia (n = 2) and Asia (n = 1). Most focused on hand hygiene and healthcare staff. Barriers and facilitators were identified across five CFIR domains. <i>Intervention characteristics:</i> Complex, untailored guidelines hindered use, while concise, context-specific protocols and adequate supplies enhanced adherence. <i>Individual characteristics:</i> Knowledge gaps, low risk perception, and competing priorities reduced adherence, whereas motivation, outbreak experience, and professional responsibility supported compliance. <i>Inner setting:</i> Staff shortages, high workload, and limited leadership were major barriers, while managerial engagement, supportive culture, and IPC champions promoted success of IPC. <i>Outer setting:</i> Limited policy support constrained implementation, whereas collaboration with public health agencies and peer networks facilitated it. <i>Implementation process:</i> limitations were lack of structured approaches; but ongoing training, peer feedback, and evaluation were key facilitators.</p><p><strong>Conclusion: </strong>Many barriers and facilitators towards IPC in LTCFs were identified that can inform future implementation strategies. Implementation processes were rarely considered and need attention in research and practice.</p>","PeriodicalId":13663,"journal":{"name":"Infection Control and Hospital Epidemiology","volume":" ","pages":"1-10"},"PeriodicalIF":2.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149109214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pseudo-outbreak of <i>Burkholderia contaminans</i> in a breast imaging center - CORRIGENDUM.","authors":"Sharon C Thompson, Emily E Sickbert-Bennett, Lauren M DiBiase, David J Weber, Lisa J Teal","doi":"10.1017/ice.2026.10536","DOIUrl":"10.1017/ice.2026.10536","url":null,"abstract":"","PeriodicalId":13663,"journal":{"name":"Infection Control and Hospital Epidemiology","volume":" ","pages":"1076"},"PeriodicalIF":2.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148864800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Uptake of the Ethical Infection Prevention and Control (EIPAC) framework: a binational survey.","authors":"Heather L Candon, Lisa Caffery, Deb Burdsall, Gerry Hansen, Jerome A Leis","doi":"10.1017/ice.2026.10523","DOIUrl":"10.1017/ice.2026.10523","url":null,"abstract":"<p><p>The Ethical Infection Prevention and Control (EIPAC) framework was introduced in 2024. In this binational survey assessing uptake, 12.3% of respondents working in IPAC report using the framework in a variety of complex situations. Lack of awareness regarding existence of EIPAC framework was most common barrier to adopting in practice.</p>","PeriodicalId":13663,"journal":{"name":"Infection Control and Hospital Epidemiology","volume":" ","pages":"1064-1066"},"PeriodicalIF":2.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148818237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of ethyl alcohol nasal treatment on hospital-onset <i>Staphylococcus aureus</i> bacteremia at a tertiary health system.","authors":"Donna Nucci, Jennifer H Sather, Michael Aniskiewicz, Scott C Roberts","doi":"10.1017/ice.2026.10529","DOIUrl":"10.1017/ice.2026.10529","url":null,"abstract":"<p><strong>Introduction: </strong><i>Staphylococcus</i> aureus is a common pathogen that can cause nosocomial infection. Ethyl alcohol has emerged as a potential alternative to mupirocin and povidone-iodine for nasal decolonization; however, data on real-world application are limited.</p><p><strong>Methods: </strong>A quasi-experiment study was performed. Twice daily 62% ethyl alcohol nasal swabs were offered to inpatients at risk for MRSA acquisition. Compliance was monitored and reasons for non-adherence were evaluated. Rates of hospital-onset <i>S. aureus</i> bacteremia were compared pre and postintervention.</p><p><strong>Results: </strong>A total of 274,999 doses of ethyl alcohol were administered to 12,179 high-risk inpatients with a compliance rate of 82.7%. Reasons for non-compliance centered on product characteristics, patient comorbidities, and perceived lack of benefit from patients and healthcare personnel. There were fewer overall hospital-onset <i>S. aureus</i> bacteremia events (1.97 events/10,000 patients days predecolonization compared to 1.49 events/10,000 patient days with decolonization, P = .013). This difference was primarily driven by reduced MRSA bacteremia events (0.61 events/10,000 patient days predecolonization versus 0.36 with decolonization, P = .009) rather than MSSA bacteremia events (1.31 events/10,000 patient days predecolonization versus 1.13 events/10,000 patient days with decolonization, P = .232). On a per-patient basis during the intervention period, there were fewer MRSA bacteremia events in patients receiving decolonization (6.57 events per 10,000 patients) compared to high-risk, but eligible, patients who did not receive decolonization (19.62 episodes per 10,000 patients, P = .044).</p><p><strong>Conclusion: </strong>Twice daily ethyl alcohol nasal treatment may be a viable alternative to existing S. aureus nasal decolonization options.</p>","PeriodicalId":13663,"journal":{"name":"Infection Control and Hospital Epidemiology","volume":" ","pages":"1007-1011"},"PeriodicalIF":2.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148827955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Targeted blower-assisted thermal disinfection for persistent distal outlet Legionella contamination in a tertiary hospital water system.","authors":"Jiahua Seah, Deborah Chooi Mun Lai, Hui Xian Toh, Chai Yin Soh, Ismawati Mohd Amin, Moi Lin Ling","doi":"10.1017/ice.2026.10526","DOIUrl":"10.1017/ice.2026.10526","url":null,"abstract":"","PeriodicalId":13663,"journal":{"name":"Infection Control and Hospital Epidemiology","volume":" ","pages":"1074-1075"},"PeriodicalIF":2.6,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148701256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}