Infection Control and Hospital Epidemiology最新文献

{"title":"A ceiling-mounted far-ultraviolet-C light technology reduces methicillin-resistant <i>Staphylococcus aureus</i> contamination on surfaces in a simulated operating room.","authors":"Samir Memic, Jennifer L Cadnum, Curtis J Donskey","doi":"10.1017/ice.2025.10231","DOIUrl":"https://doi.org/10.1017/ice.2025.10231","url":null,"abstract":"","PeriodicalId":13663,"journal":{"name":"Infection Control and Hospital Epidemiology","volume":" ","pages":"1-2"},"PeriodicalIF":2.9,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145029496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk of viral respiratory infection associated with shared washroom between adjoining rooms: a test-negative study.","authors":"Victoria Williams, Karoleen Volpentesta, Melisa Avaness, Christina Chan, Radhika Chawla, Amna Rizvi, Payton Bayley, Rob Kozak, Jerome A Leis","doi":"10.1017/ice.2025.10262","DOIUrl":"https://doi.org/10.1017/ice.2025.10262","url":null,"abstract":"<p><p>In test-negative study of residents exposed to viral respiratory infection (VRI), odds of VRI (excluding SARS-CoV-2) was higher with shared room (OR = 2.28, 95% CI, 1.53-3.40) and shared adjoining washroom (OR = 1.65, 95% CI, 1.03-2.64) than neighboring rooms. Measures recommended for exposed residents in shared rooms should be considered for shared washrooms.</p>","PeriodicalId":13663,"journal":{"name":"Infection Control and Hospital Epidemiology","volume":" ","pages":"1-3"},"PeriodicalIF":2.9,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145029668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The life cycle of infection prevention and antimicrobial stewardship projects and interventions: the dynamic interplay of implementation and de-implementation science (Part I of II).","authors":"Westyn Branch-Elliman, David A Chambers, Owen Albin, Lynne Batshon, Sandra Castejon-Ramirez, Vincent Chi-Chung Cheng, Nkechi Emetuche, Rupak Datta, Mini Kamboj, Sarah L Krein, Milner Staub, Samira Reyes Dassum, Barry Rittmann, Felicia Scaggs Huang, Pranavi Sreeramoju, Stephanie Stroever, Geehan Suleyman, Joseph Y Ting, Lucy S Witt, Matthew J Ziegler, Jennie H Kwon","doi":"10.1017/ice.2025.75","DOIUrl":"https://doi.org/10.1017/ice.2025.75","url":null,"abstract":"<p><p>In Antimicrobial Stewardship and Infection Prevention and Control, programmatic goals often strive to achieve clinical benefit by practice change in the direction of doing less. Practically, this may include reducing the number of tests ordered, encouraging shorter and more narrow courses of antimicrobials, or discontinuing practices that are no longer contextually appropriate. Because promoting practice change in the direction of doing less is a critical aspect of day-to-day operations in Antimicrobial Stewardship and Infection Prevention and Control, the goals of this <i>Society for Healthcare Epidemiology</i> Research Committee White Paper are to provide a roadmap and framework for leveraging principles of implementation and de-implementation science in day-to-day practice. Part II of this series focuses on some practical case studies, including real-world examples of applied de-implementation science to promote discontinuation of practices that are ineffective, overused, or no longer effective.</p>","PeriodicalId":13663,"journal":{"name":"Infection Control and Hospital Epidemiology","volume":" ","pages":"1-12"},"PeriodicalIF":2.9,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145029636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An interrupted time-series analysis assessing the association of the COVID-19 pandemic on healthcare-associated infections and antimicrobial-resistant organisms in Canadian acute care hospitals, 2018-2022.","authors":"Anada Silva, Jessica J Bartoszko, Joëlle Cayen, Kelly B Choi, Robyn Mitchell, Jeannette L Comeau, Charles Frenette, Susy S Hota, Jennie Johnstone, Kevin C Katz, Stephanie W Smith, Jocelyn A Srigley, Kathryn N Suh, Nisha Thampi","doi":"10.1017/ice.2025.10247","DOIUrl":"https://doi.org/10.1017/ice.2025.10247","url":null,"abstract":"","PeriodicalId":13663,"journal":{"name":"Infection Control and Hospital Epidemiology","volume":" ","pages":"1-5"},"PeriodicalIF":2.9,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145029582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interrupted time-series analysis to evaluate the impact of a national antimicrobial stewardship campaign on antibiotic use among primary healthcare institutions: evidence from Central China.","authors":"Yirui Xu, Yingying Wang, Hanyu Qian, Xian Liu, Dongyang Lan, Jue Wang, Yuxiao Zhang","doi":"10.1017/ice.2025.10266","DOIUrl":"https://doi.org/10.1017/ice.2025.10266","url":null,"abstract":"<p><strong>Objective: </strong>Antimicrobial resistance (AMR) is a global health challenge, highlighting the need for antibiotic stewardship policies. We evaluated the impact of the National Action Plan to Contain Antimicrobial Resistance (2022-2025) on antibiotic use among primary healthcare institutions (PHIs) in Central China.</p><p><strong>Design: </strong>A segmented interrupted time-series analysis from January 2021 to December 2023.</p><p><strong>Methods: </strong>We collected data from 1510 PHIs, by region, types of healthcare institutions and medication type, assessing antibiotic consumption using defined daily doses per 1000 inhabitants per day and the quality by the percentage of broad-spectrum antibiotics.</p><p><strong>Results: </strong>Post-intervention, antibiotic consumption declined by -35.96% (95%CI: -49.34 to -22.57), and the proportion of broad-spectrum antibiotic use decreased by -41.97% (-61.74 to -22.20). Consumption dropped significantly in both moderately developed areas and underdeveloped areas, while highly developed areas saw the largest reduction in broad-spectrum antibiotic use. Rural PHIs also showed notable declines in both overall antibiotic consumption and broad-spectrum usage.</p><p><strong>Conclusions: </strong>The policy was associated with a reduction in antibiotic use across PHIs, though regional disparities in its implementation suggest uneven benefits.</p>","PeriodicalId":13663,"journal":{"name":"Infection Control and Hospital Epidemiology","volume":" ","pages":"1-7"},"PeriodicalIF":2.9,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145029506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multiyear environmental surveillance in a pediatric teaching hospital: association between airborne mold spores and invasive mold infections.","authors":"Bethany Phillips, Zachary M Most, Bryan Connors, Patricia Jackson, Michael E Sebert","doi":"10.1017/ice.2025.10264","DOIUrl":"https://doi.org/10.1017/ice.2025.10264","url":null,"abstract":"<p><strong>Background: </strong>The utility of routine environmental sampling to monitor the airborne fungal load (AFL) in healthcare settings is uncertain.</p><p><strong>Methods: </strong>AFL was measured by monthly cultures at a tertiary-care pediatric hospital from November 2018 through October 2023 on eleven units caring for patients at risk for invasive mold infection (IMI). Surveillance for healthcare-associated IMI was conducted for all patients in the healthcare system using locally developed definitions for possible, probable, and definite hospital-onset infections. Poisson regression was used to analyze the association between AFL and monthly IMI rates.</p><p><strong>Results: </strong>78 cases of IMI were identified during the period of AFL monitoring. Of these, 51 infections were classified as healthcare-associated probable or proven IMI and were tested for association with AFL measurements. There was not a significant facility-wide association between the average monthly AFL and the overall IMI rate. On units where hematology/oncology patients were treated, however, an increase in average monthly local AFL for opportunistic fungal pathogens of 1 CFU/m³ was associated with a 1.48-fold increase in the IMI rate for these patients (95% CI 1.00-2.19, <i>P</i> = .05). The AFL for <i>Aspergillus</i> species on these units showed a particularly strong association with the hematology/oncology IMI rate (15.9-fold elevation for an increase of 1 CFU/m³ [95% CI 2.8-90.7, <i>P</i> = .002]). Neither hematology/oncology nor facility-wide IMI rates showed comparable associations with changes of the AFL in outdoor air.</p><p><strong>Conclusions: </strong>Regular monitoring of AFL on targeted hospital units may identify periods when hematology/oncology patients are at increased risk for IMI.</p>","PeriodicalId":13663,"journal":{"name":"Infection Control and Hospital Epidemiology","volume":" ","pages":"1-8"},"PeriodicalIF":2.9,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145029514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Leveraging de-implementation science to promote infection prevention and stewardship: a roadmap and practical examples (Part II of II).","authors":"Westyn Branch-Elliman, Samira Reyes Dassum, Stephanie Stroever, Owen Albin, Lynne Batshon, Sandra Castejon-Ramirez, Vincent Chi-Chung Cheng, Nkechi Emetuche, Rupak Datta, Mini Kamboj, Sarah L Krein, Milner Staub, Barry Rittmann, Felicia Scaggs Huang, Pranavi Sreeramoju, Geehan Suleyman, Joseph Y Ting, Lucy S Witt, Matthew J Ziegler, Jennie H Kwon","doi":"10.1017/ice.2025.76","DOIUrl":"https://doi.org/10.1017/ice.2025.76","url":null,"abstract":"<p><p>De-implementation of established practices is a common challenge in infection prevention and antimicrobial stewardship and a necessary part of the life cycle of healthcare quality improvement programs. Promoting de-implementation of ineffective antimicrobial use and increasingly of low-value diagnostic testing are cornerstones of stewardship practice. Principles of de-implementation science and the interplay of implementation and de-implementation are discussed in part I of this Society for Healthcare Epidemiology of America White Paper Series.In this second part of the series, we discuss a process for applying principles of de-implementation science in infection prevention and stewardship and then review some real-world examples and case studies, including a national blood culture shortage, contact precautions, and surgical and dental prophylaxis. We use these examples to demonstrate how barriers and facilitators can be mapped to evidence-informed implementation/de-implementation strategies to promote efforts to reduce low-value, ineffective, or out-of-date practices. These real-world examples highlight the need for infection prevention and stewardship programs to adapt to changing evidence, contexts, and conditions. Although barriers to practice change are often a bit different, de-implementation can sometimes be thought of as the implementation of a new program-but the new program aims to stop rather than start doing something.As the saying goes, sometimes less really is more. Medicine and public health have a strong action bias and a strong aversion to risk and uncertainty. Although our best intentions may point us to implementing more interventions, often, the best medicine instead dictates that we do less, or nothing at all. Leveraging principles of de-implementation science can help move healthcare in the right direction when interventions are low-value, ineffective, or no longer needed.</p>","PeriodicalId":13663,"journal":{"name":"Infection Control and Hospital Epidemiology","volume":" ","pages":"1-11"},"PeriodicalIF":2.9,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145029537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does one size fit all for contact precautions implementation? Impact of requiring use of gloves and gowns for every room entry on personnel time, personal protective equipment costs, and carbon footprint.","authors":"Amelia L Milner, Elizabeth C Eckstein, Curtis J Donskey","doi":"10.1017/ice.2025.10257","DOIUrl":"https://doi.org/10.1017/ice.2025.10257","url":null,"abstract":"<p><p>In an observational study, healthcare personnel often entered contact precautions rooms without contacting patients or the environment. An approach requiring gloves and gowns based on actual contacts rather than for all room entries would reduce personal protective equipment donning and doffing time, cost, and carbon footprint by more than half.</p>","PeriodicalId":13663,"journal":{"name":"Infection Control and Hospital Epidemiology","volume":" ","pages":"1-3"},"PeriodicalIF":2.9,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145029527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trends in healthcare-associated infections and antimicrobial-resistant organisms among adults in Canadian acute care hospitals: findings from four point prevalence surveys, 2002 to 2024.","authors":"Robyn Mitchell, Diane Lee, Jessica Bartoszko, Cassandra Lybeck, Marie-Ève Benoit, Jeannette Comeau, Jennifer Ellison, Charles Frenette, Jennifer Happe, Nicole Haslam, Bonita Lee, Dominik Mertz, Stephanie W Smith, Daniel Thirion, Alice Wong, Michelle Science, Susy Hota","doi":"10.1017/ice.2025.10259","DOIUrl":"https://doi.org/10.1017/ice.2025.10259","url":null,"abstract":"<p><strong>Objective: </strong>To describe trends in the prevalence of healthcare-associated infections (HAIs) and antibiotic-resistant organisms (AROs) in Canadian acute-care hospitals.</p><p><strong>Design: </strong>Repeated point prevalence surveys.</p><p><strong>Setting: </strong>Canadian Nosocomial Infection Surveillance Program (CNISP) hospitals.</p><p><strong>Methods: </strong>Trained infection control professionals reviewed medical records of eligible adult patients and applied standardized definitions to collect demographic data and information on HAIs, AROs, and additional precautions from 39 to 62 hospitals in 2002, 2009, 2017, and 2024.</p><p><strong>Results: </strong>The prevalence of adult patients with at least one HAI increased from 10.4% (95% CI: 9.6%-11.2%) in 2002 to 12.4% (95% CI: 11.7%-13.2%) in 2009, declined to 8.4% (95% CI: 7.8%-9.0%) in 2017, and stabilized in 2024 (8.1%, 95% CI: 7.6%-8.6%) despite 3.1% of HAIs being due to SARS-CoV-2. Between 2017 and 2024, there were increases in bloodstream infections (1.0% to 1.5%, <i>p</i> = 0.002), viral respiratory infections (VRI) (0.3% to 0.6%, <i>p</i> < 0.001), and in the prevalence of patients on additional precautions for carbapenemase-producing organisms (0.1% to 1.7%, <i>p</i> < 0.001) and VRIs (2.1% to 3.6%, <i>p</i> < 0.001). In 2024, AROs were responsible for 6.6% of infections. One-third of HAIs were device-associated, and the prevalence of central line-associated bloodstream infections (CLABSIs) doubled from 0.4% in 2017 to 0.7% in 2024, <i>p</i> = 0.02.</p><p><strong>Conclusions: </strong>A point prevalence survey performed in Canada in 2024 following the COVID-19 pandemic identified a stable prevalence of HAIs and AROs despite the inclusion of SARS-CoV-2. Concerning trends were observed including the increased prevalence of certain HAIs such as CLABSIs and VRIs highlighting the need for ongoing efforts in hospital infection prevention.</p>","PeriodicalId":13663,"journal":{"name":"Infection Control and Hospital Epidemiology","volume":" ","pages":"1-8"},"PeriodicalIF":2.9,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145029619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Consequences of reported β-lactam allergy on perioperative outcomes: a systematic review and meta-analysis of surgical site infection risk.","authors":"Yuki Hanai, Jun Hirai, Kazuhiro Matsuo, Keita Kouzu, Hiroji Shinkawa, Seiichi Shinji, Motomu Kobayashi, Yuichi Kitagawa, Chizuru Yamashita, Yasuhiko Mohri, Hiroshi Nobuhara, Katsunori Suzuki, Junzo Shimizu, Motoi Uchino, Seiji Haji, Masahiro Yoshida, Toru Mizuguchi, Toshihiko Mayumi, Yuko Kitagawa, Hiroki Ohge","doi":"10.1017/ice.2025.10294","DOIUrl":"https://doi.org/10.1017/ice.2025.10294","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the impact of reported β-lactam allergy on the risk of surgical site infections (SSIs), given that most reported cases are unverified and may lead to suboptimal antibiotic prophylaxis.</p><p><strong>Design: </strong>Systematic review and meta-analysis.</p><p><strong>Methods: </strong>Four databases were systematically searched for studies reporting SSI rates in patients with and without β-lactam allergy. The primary outcome was SSI incidence; secondary outcomes included mortality, length of hospital stay (LOS) and adverse events. Subgroup analyses were conducted to explore potential sources of heterogeneity. Risk ratios (RRs) with 95% confidence intervals (CIs) were pooled using a random-effects model. Risk of bias was assessed using the ROBINS-I tool.</p><p><strong>Results: </strong>Twenty-five retrospective observational studies comprising 460,284 patients were included. Reported β-lactam allergy was associated with a significantly increased risk of SSI (RR = 1.55, 95% CI = 1.24-1.94). This association remained consistent across sensitivity and subgroup analyses, particularly in studies relying on self-reported allergies. Patients receiving β-lactam antibiotics had a significantly lower SSI risk than that of patients receiving non-β-lactam alternatives (RR = 0.63, 95% CI = 0.42-0.94). No significant differences were found in LOS or hypersensitivity reaction rates. Mortality was not reported in any of the included studies.</p><p><strong>Conclusions: </strong>Reported β-lactam allergy is associated with an increased risk of SSI, highlighting the importance of accurate allergy assessment. Selective administration of β-lactam agents, such as cefazolin, may offer a safe and effective option for preoperative prophylaxis in patients without a history of severe hypersensitivity.</p>","PeriodicalId":13663,"journal":{"name":"Infection Control and Hospital Epidemiology","volume":" ","pages":"1-11"},"PeriodicalIF":2.9,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145029545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}