Infection Control and Hospital Epidemiology最新文献

{"title":"Isolating the burden of transmission-based precautions for COVID-19: walk-in clinic-based healthcare personnel perspectives.","authors":"Rebecca A Stern, Katherine Bashaw, Thomas R Talbot","doi":"10.1017/ice.2025.84","DOIUrl":"https://doi.org/10.1017/ice.2025.84","url":null,"abstract":"","PeriodicalId":13663,"journal":{"name":"Infection Control and Hospital Epidemiology","volume":" ","pages":"1-2"},"PeriodicalIF":3.0,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144077652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Respiratory syncytial virus: an under-recognized healthcare-associated infection.","authors":"Erin B Gettler, H Keipp Talbot, Yuwei Zhu, Danielle Ndi, Edward Mitchel, Tiffanie M Markus, William Schaffner, Bryan Harris, Thomas R Talbot","doi":"10.1017/ice.2025.88","DOIUrl":"https://doi.org/10.1017/ice.2025.88","url":null,"abstract":"<p><strong>Objective: </strong>Prior reports of healthcare-associated respiratory syncytial virus (RSV) have been limited to cases diagnosed after the third day of hospitalization. The omission of other healthcare settings where RSV transmission may occur underestimates the true incidence of healthcare-associated RSV.</p><p><strong>Design: </strong>Retrospective cross-sectional study.</p><p><strong>Setting: </strong>United States RSV Hospitalization Surveillance Network (RSV-NET) during 2016-2017 through 2018-2019 seasons.</p><p><strong>Patients: </strong>Laboratory-confirmed RSV-related hospitalizations in an eight-county catchment area in Tennessee.</p><p><strong>Methods: </strong>Surveillance data from RSV-NET were used to evaluate the population-level burden of healthcare-associated RSV. The incidence of healthcare-associated RSV was determined using the traditional definition (i.e., positive RSV test after hospital day 3) in addition to often under-recognized cases associated with recent post-acute care facility admission or a recent acute care hospitalization for a non-RSV illness in the preceding 7 days.</p><p><strong>Results: </strong>Among the 900 laboratory-confirmed RSV-related hospitalizations, 41 (4.6%) had traditionally defined healthcare-associated RSV. Including patients with a positive RSV test obtained in the first 3 days of hospitalization and who were either transferred to the hospital directly from a post-acute care facility or who were recently discharged from an acute care facility for a non-RSV illness in the preceding 7 days identified an additional 95 cases (10.6% of all RSV-related hospitalizations).</p><p><strong>Conclusions: </strong>RSV is an often under-recognized healthcare-associated infection. Capturing other healthcare exposures that may serve as the initial site of viral transmission may provide more comprehensive estimates of the burden of healthcare-associated RSV and inform improved infection prevention strategies and vaccination efforts.</p>","PeriodicalId":13663,"journal":{"name":"Infection Control and Hospital Epidemiology","volume":" ","pages":"1-5"},"PeriodicalIF":3.0,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144077667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding hand hygiene adherence in neonatology: a qualitative study of behavioral determinants.","authors":"Tamara C Bopp, Yvonne Strässle, Colette Wyler, Marie-Theres Meier, Lauren Clack, Walter Zingg, Jehudith R Fontijn, Aline Wolfensberger","doi":"10.1017/ice.2025.82","DOIUrl":"https://doi.org/10.1017/ice.2025.82","url":null,"abstract":"<p><strong>Background: </strong>Hand hygiene is effective to prevent transmission of pathogens and healthcare-associated infections. Despite efforts by hospitals to improve hand hygiene adherence among healthcare practitioners (HCP), adherence in neonatology wards is often limited.</p><p><strong>Objective: </strong>Identifying determinants, i.e., facilitators and barriers, to hand hygiene adherence among frontline HCP in neonatology.</p><p><strong>Design: </strong>Qualitative implementation research study.</p><p><strong>Setting: </strong>Department of Neonatology of the University Hospital Zurich, Switzerland.</p><p><strong>Methods: </strong>Semi-structured interviews with frontline HCP and Infection Prevention and Control (IPC) experts were conducted in November 2022. Interviews were coded deductively according to the Theoretical Domains Framework (TDF) and the Capability, Opportunity, Motivation and Behavior model (COM-B), and inductively to capture nuances in the data. Determinants whose addressing was perceived to likely improve hand hygiene adherence in the current setting were rated as \"high priority\".</p><p><strong>Results: </strong>A total of 42 interviews were conducted, 27 (64%) with nurses, six (14%) with physicians, four (10%) with other professions, and five (12%) with IPC experts. Sixteen determinants were identified, twelve of which were high-priority, four in each COM-B domain. Knowledge, attention control, planning workflows, and habits & automatisms were found in \"Capability,\" workload & emergencies, invisibility of germs, role models, and being observed in \"Opportunity,\" and bad conscience, experience consequences of (non-) adherence, self-reflection, and intention to adhere to hand hygiene in \"Motivation.\"</p><p><strong>Discussion/conclusion: </strong>Facilitators from all COM-B domains and barriers from \"Capability\" and \"Opportunity\" influence hand hygiene behavior in neonatology settings. Our findings can now inform interventions to improving hand hygiene adherence in neonatal settings.</p>","PeriodicalId":13663,"journal":{"name":"Infection Control and Hospital Epidemiology","volume":" ","pages":"1-9"},"PeriodicalIF":3.0,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144077732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sustainability and spread of best practices for peri-operative antimicrobial stewardship following discontinuation of mandatory public reporting: perceptions from the Society for Healthcare Epidemiology in America research network.","authors":"Jacquelyn Pendergast, Hillary Mull, Marlena Shin, Ryann Engle, A Rani Elwy, Judith Strymish, Samuel Golenbock, Kierstin Hederstedt, Rory Ostrow, Matthew Bidwell Goetz, Mary Hawn, Westyn Branch-Elliman","doi":"10.1017/ice.2025.61","DOIUrl":"https://doi.org/10.1017/ice.2025.61","url":null,"abstract":"<p><strong>Background: </strong>A Joint Commission national program, the surgical care improvement project (SCIP), supported the adoption of evidence-based peri-operative antimicrobial use practices, including administration of antimicrobials prior to incision and early discontinuation after skin closure. With high compliance, in 2015, the public reporting requirement that provided external pressure to support practice improvements was discontinued. Since discontinuation, few studies have assessed the sustainment of best antimicrobial use practices and what procedures were developed to maintain improvements within facilities.</p><p><strong>Objective: </strong>The aim of this study was to measure perceptions among antimicrobial stewardship experts about which policies and practices have been important and effective for sustainment.</p><p><strong>Design: </strong>A 15-min survey was administered to the Society for Hhealthcare Epidemiology in America (SHEA) research network over the summer of 2023. The survey included questions about different SCIP measures such as prophylactic antibiotic use pre and post-surgery and about local policies and procedures that were implemented to support best practices. Simple descriptive statistics were utilized to analyze results.</p><p><strong>Results: </strong>The survey was distributed to 112 members of the SHEA research network, with a 41% response rate. Most respondents perceived high rates of ongoing compliance with both pre- and post-operative prophylaxis guidelines, although ongoing surveillance and measurement is limited. Respondents perceived that the most important internal factors associated with ongoing compliance were electronic order sets, facility policies, time outs, and automatic stop orders. Substantial spread of best practices (eg, to surgical procedures and specialties not covered until the SCIP program) was reported.</p><p><strong>Conclusions: </strong>Despite discontinuation of mandated reporting, antimicrobial stewards perceived ongoing compliance with SCIP measures. Local policies and procedures implemented to support initial uptake of best practices have supported ongoing sustainment of practice improvements.</p>","PeriodicalId":13663,"journal":{"name":"Infection Control and Hospital Epidemiology","volume":" ","pages":"1-6"},"PeriodicalIF":3.0,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144077684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characterizing presenteeism among healthcare personnel at an academic medical center across eras of the COVID-19 pandemic.","authors":"Amanda Brown Marusiak, Emily Sickbert-Bennett, Hilary Babcock, Daniel Westreich, Justin Lessler, David Weber","doi":"10.1017/ice.2025.69","DOIUrl":"https://doi.org/10.1017/ice.2025.69","url":null,"abstract":"<p><strong>Objective: </strong>To assess the frequency of and motivations for acute respiratory illness (ARI) presenteeism in healthcare personnel (HCP) during two waves of COVID-19.</p><p><strong>Design: </strong>Survey.</p><p><strong>Setting: </strong>Large academic medical center, both ambulatory and acute care settings.</p><p><strong>Participants: </strong>All HCPs (n = 11,429) at the University of North Carolina Medical Center were eligible for two voluntary, electronic surveys: pre-Omicron (n = 591, recall period March 2020 - December 2021) and Omicron BA.1 (n = 385, recall period January - April 2022).</p><p><strong>Methods: </strong>We compared self-reported ARI presenteeism (working despite feeling feverish plus cough and/or sore throat) and motivators across time and demographics. We also estimated effects of workplace perceptions and culture on ARI presenteeism with log-binomial regression, adjusting for age, gender, HCP role, and patient interaction.</p><p><strong>Results: </strong>In the pre-Omicron and Omicron BA.1 eras, 24% and 34% of respondents respectively reported at least one instance of ARI presenteeism. In both eras, clinical frontline HCP were more likely to report ARI presenteeism than other roles, as were HCP primarily providing direct patient care vs not. Pre-Omicron motivators included disciplinary action and sick leave concerns, whereas workplace culture predominated during Omicron. Feeling professional obligation to attend work and observing colleague presenteeism increased ARI presenteeism in both eras. During Omicron, COVID-19 burnout, fatigue, and unclear call-out procedures increased ARI presenteeism.</p><p><strong>Conclusions: </strong>ARI presenteeism was common and had diverse motivations, including workplace culture, disciplinary action, and sick leave. Efforts to reduce presenteeism should address these factors and prioritize frontline clinical personnel with direct patient interaction.</p>","PeriodicalId":13663,"journal":{"name":"Infection Control and Hospital Epidemiology","volume":" ","pages":"1-9"},"PeriodicalIF":3.0,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144077710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A discrete choice experiment to evaluate healthcare personnel preferences regarding risk-tailored policies for contact precautions for patients with methicillin-resistant <i>Staphylococcus aureus</i>.","authors":"Lyndsay M O'Hara, David P Calfee, Graham M Snyder, Elise M Martin, Nicholas F Angelino, Nathan N O'Hara, Anthony D Harris","doi":"10.1017/ice.2025.65","DOIUrl":"https://doi.org/10.1017/ice.2025.65","url":null,"abstract":"<p><strong>Background: </strong>An alternative to an \"all or none\" approach to contact precautions for patients with MRSA carriage may be a \"risk-tailored\" approach - using gloves and gowns only for certain high-risk activities, locations, or roles.</p><p><strong>Methods: </strong>We distributed a discrete choice experiment to healthcare personnel (HCPs) in three cities. Respondents were presented with eight choice sets, each consisting of two hypothetical policy options for glove and gown use to prevent MRSA transmission. In each comparison, respondents selected their preferred option. Using mixed logit modeling we calculated utility derived from each policy component, probability of uptake for the most favored policies, and heterogeneity in preferences based on HCP role.</p><p><strong>Results: </strong>In total, 326 HCPs completed the survey. 237 (54%) respondents reported wearing gloves and gowns 'all the time' when required. Respondents' preferred policy with the highest utility score was to use gloves and gown for all HCPs roles (utility, 0.17; 95% CI, 0.12 to 0.23), in high-risk settings (utility, 0.12; 95% CI 0.07-0.18), when touching the patient (utility, 0.11; 95% CI 0.06-0.17). Sixty-three percent (95% CI 60-66) would support a risk-tailored approach over an approach where contact precautions are used by all HCPs in all settings and for all activities. Support varied by HCP role (p < 0.02), with the strongest probability of support from physicians and advanced practice providers (77%, 95% CI 72%-82%) and the least support from environmental services personnel (45%, 95% CI 37%-53%).</p><p><strong>Conclusions: </strong>This discrete choice survey demonstrates that most HCPs prefer a risk-tailored approach to contact precautions when caring for patients with MRSA.</p>","PeriodicalId":13663,"journal":{"name":"Infection Control and Hospital Epidemiology","volume":" ","pages":"1-6"},"PeriodicalIF":3.0,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144077550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"SHEA/APIC/IDSA/PIDS multisociety position paper: Raising the bar: necessary resources and structure for effective healthcare facility infection prevention and control programs.","authors":"Thomas R Talbot, Christopher Baliga, Rebecca Crapanzano-Sigafoos, Tania N Bubb, Mohamad Fakih, Thomas G Fraser, Ibukunoluwa C Kalu, Vidya Mony, Anupama Neelakanta, Ann-Christine Nyquist, Catherine O'Neal, Jan E Patterson, David K Warren, Sharon B Wright","doi":"10.1017/ice.2025.73","DOIUrl":"https://doi.org/10.1017/ice.2025.73","url":null,"abstract":"<p><p>The Society for Healthcare Epidemiology of America, the Association of Professionals in Infection Control and Epidemiology, the Infectious Diseases Society of America, and the Pediatric Infectious Diseases Society represent the core expertise regarding healthcare infection prevention and infectious diseases and have written multisociety statement for healthcare facility leaders, regulatory agencies, payors, and patients to strengthen requirements and expectations around facility infection prevention and control (IPC) programs. Based on a systematic literature search and formal consensus process, the authors advocate raising the expectations for facility IPC programs, moving to effective programs that are:• Foundational and influential parts of the facility's operational structure• Resourced with the correct expertise and leadership• Prioritized to address all potential infectious harmsThis document discusses the IPC program's leadership-a dyad model that includes both physician and infection preventionist leaders-its reporting structure, expertise, and competencies of its members, and the roles and accountability of partnering groups within the healthcare facility. The document outlines a process for identifying minimum IPC program medical director support. It applies to all types of healthcare settings except post-acute long-term care and focuses on resources for the IPC program. Long-term acute care hospital (LTACH) staffing and antimicrobial stewardship programs will be discussed in subsequent documents.</p>","PeriodicalId":13663,"journal":{"name":"Infection Control and Hospital Epidemiology","volume":" ","pages":"1-19"},"PeriodicalIF":3.0,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143978877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multisociety guidance for sterilization and high-level disinfection.","authors":"Erica S Shenoy, David J Weber, Kathleen McMullen, Zachary Rubin, Priya Sampathkumar, Joshua K Schaffzin, Emily Sickbert-Bennett, Laraine Washer, Deborah S Yokoe, Audrey H Calderwood, Raymond Chinn, Michelle Day, Sylvia Garcia-Houchins, Waleed Javaid, Susan Klacik, Erin Kyle, Rekha K Murthy, Amber Wood, William A Rutala","doi":"10.1017/ice.2025.41","DOIUrl":"https://doi.org/10.1017/ice.2025.41","url":null,"abstract":"<p><p>SHEA, in partnership with ASGE, APIC, AAMI, AORN, HSPA, IDSA, SGNA, and The Joint Commission, developed this multisociety infection prevention guidance document for individuals and organizations that engage in sterilization or high-level disinfection (HLD). This document follows the <i>CDC Guideline for Disinfection and Sterilization in Healthcare Facilities</i>. This guidance is based on a synthesis of published scientific evidence, theoretical rationale, current practices, practical considerations, writing group consensus, and consideration of potential harm when applicable. The supplementary material includes a summary of recommendations. The guidance provides an overview of the Spaulding Classification and considerations around manufacturers' instructions for use (MIFUs). Its recommendations address: point-of-use treatment prior to sterilization or HLD, preparation of reusable medical devices at the location of processing, sterilization, and immediate use steam sterilization (IUSS), HLD of lumened and non-lumened devices, processing of reusable medical devices used with lubricating or defoaming agents, monitoring for effectiveness of processing, handling of devices after HLD, augments and alternatives to HLD, processing of investigational devices, tracking of reusable medical devices, and approaches to implementation.</p>","PeriodicalId":13663,"journal":{"name":"Infection Control and Hospital Epidemiology","volume":" ","pages":"1-23"},"PeriodicalIF":3.0,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143985398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"COVID-19 prevention training with video-based feedback in nursing homes: impact on staff safety behaviors.","authors":"Victoria Ngai, Joshua B Hsi, Raveena D Singh, John E Mitchell, Raheeb Saavedra, Shruti K Gohil, Emily A Hsi, Robert Pedroza, Chase Berman, Kristine P Nguyen, Matthew Zahn, Emily Fonda, Susan S Huang, Gabrielle M Gussin","doi":"10.1017/ice.2025.77","DOIUrl":"https://doi.org/10.1017/ice.2025.77","url":null,"abstract":"<p><strong>Objective: </strong>Evaluate impact of COVID-19 prevention training with video-based feedback on nursing home (NH) staff safety behaviors.</p><p><strong>Design: </strong>Public health intervention.</p><p><strong>Setting & participants: </strong>Twelve NHs in Orange County, California, 6/2020-4/2022.</p><p><strong>Methods: </strong>NHs received direct-to-staff COVID-19 prevention training and weekly feedback reports with video montages about hand hygiene, mask-wearing, and mask/face-touching. One-hour periods of recorded streaming video from common areas (breakroom, hallway, nursing station, entryway) were sampled randomly across days of the week and nursing shifts for safe behavior. Multivariable models assessed the intervention impact.</p><p><strong>Results: </strong>Video auditing encompassed 182,803 staff opportunities for safe behavior. Hand hygiene errors improved from first (67.0%) to last (35.7%) months of the intervention, decreasing 7.6% per month (OR = 0.92, 95% CI = 0.92-0.93, <i>P</i> < 0.001); masking errors improved from first (10.3 %) to last (6.6%) months of the intervention, decreasing 2.3% per month (OR = 0.98, 95% CI = 0.97-0.99, <i>P</i> < 0.001); face/mask touching improved from first (30.0%) to last (10.6%) months of the intervention, decreasing 2.5% per month (OR = 0.98, 95% CI = 0.97-0.98, <i>P</i> < 0.001). Hand hygiene errors were most common in entryways and on weekends, with similar rates across shifts. Masking errors and face/mask touching errors were most common in breakrooms, with the latter occurring most commonly during the day (7A.M.-3P.M.) shift, with similar rates across weekdays/weekends. Error reductions were seen across camera locations, days of the week, and nursing shifts, suggesting a widespread benefit within participating NHs.</p><p><strong>Conclusion: </strong>Direct-to-staff training with video-based feedback was temporally associated with improved hand hygiene, masking, and face/mask-touching behaviors among NH staff during the COVID-19 pandemic.</p>","PeriodicalId":13663,"journal":{"name":"Infection Control and Hospital Epidemiology","volume":" ","pages":"1-8"},"PeriodicalIF":3.0,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143991912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiology and perioperative factors contributing to postoperative pneumonia in patients undergoing isolated coronary artery bypass grafting: a retrospective Chinese study.","authors":"Yuxiao Zhan, Yang Yang, Jian Zhang, Rui Yang, Guojun Zhang","doi":"10.1017/ice.2025.19","DOIUrl":"https://doi.org/10.1017/ice.2025.19","url":null,"abstract":"<p><strong>Background: </strong>Despite the existent studies investigating the risk factors for postoperative pneumonia (POP) following coronary artery bypass grafting (CABG), the comprehensive understanding of POP is constrained by the scarcity of epidemiological data.</p><p><strong>Objective: </strong>To investigate the epidemiology and contributing factors of POP in patients undergoing isolated CABG, and establish a prediction model.</p><p><strong>Design: </strong>A single center, retrospective case-control study.</p><p><strong>Setting: </strong>Seven cardiovascular surgery wards across three campuses of a large general hospital in Henan Province, Mid-China.</p><p><strong>Participants: </strong>Patients aged ≥ 18 years who underwent isolated CABG between January 1, 2020 and November 30, 2023.</p><p><strong>Methods: </strong>Univariate and multivariate analyses with restricted cubic splines (RCS) were performed to identify factors that independently contributed to POP and explore the potential nonlinear relationships. The prediction model was evaluated via receiver operating characteristic curve analysis.</p><p><strong>Results: </strong>POP occurred in 11.34% of patients (518/4569). A total of 416 pathogenic strains were isolated from 381 patients, predominantly Gram-negative bacteria (86.5%). Pathogen distribution varied annually and quarterly. Multivariate analyses indicated that age, diabetes mellitus, smoking, operative duration, red blood cell transfusion, and duration of mechanical ventilation were significantly associated with higher POP risk, whereas higher hemoglobin and total cholesterol levels indicated a reduced likelihood. RCS analysis revealed a nonlinear relationship between operative duration and POP. The prediction model demonstrated a high predictive value (C-statistic: 0.774, 95% CI: 0.735-0.813).</p><p><strong>Conclusions: </strong>This study identified eight independent factors that significantly influence the risk of POP following CABG, thereby clarifying the direction for optimizing perioperative prevention strategies for POP.</p>","PeriodicalId":13663,"journal":{"name":"Infection Control and Hospital Epidemiology","volume":" ","pages":"1-7"},"PeriodicalIF":3.0,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144013559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}