Gaetana Messina, Mary Bove, Giovanni Natale, Antonio Noro, Mario Martone, Giorgia Opromolla, Vincenzo Di Filippo, Beatrice Leonardi, Morena Fasano, Rita Polito, Alfonso Fiorelli, Mario Santini, Giovanni Vicidomini
{"title":"Ultrasound location of ground-glass opacity during thoracoscopic surgery.","authors":"Gaetana Messina, Mary Bove, Giovanni Natale, Antonio Noro, Mario Martone, Giorgia Opromolla, Vincenzo Di Filippo, Beatrice Leonardi, Morena Fasano, Rita Polito, Alfonso Fiorelli, Mario Santini, Giovanni Vicidomini","doi":"10.1093/icvts/ivac234","DOIUrl":"https://doi.org/10.1093/icvts/ivac234","url":null,"abstract":"<p><strong>Objectives: </strong>Application of video-assisted thoracoscopy brought lung surgery into the minimally invasive era; the lack of tactile feedback using VATS, remains a disadvantage because surgeons are unable to locate lesions with a finger or device. This study aimed to investigate the effectiveness, the applicability and the utility of intraoperative ultrasound (IU), for the localization of small ground-glass opacity (GGO) lesions in the parenchyma, as a guide in finding their margins in a deflated lung.</p><p><strong>Materials and methods: </strong>We included 15 consecutive patients undergoing diagnostic resection of GGOs via VATS in the Thoracic Surgery Unit of the University of 'Luigi Vanvitelli' of Naples from November 2019 to December 2021. They were under general anaesthesia, when the lung had been collapsed, the probe was placed in the region where the target lesion was thought to reside on the basis of low-dose computed tomography scanning. GGO could be identified their sizes, echo levels and posterior echo was recorded by IU when the lung was completely deflated.</p><p><strong>Results: </strong>We conducted a retrospective single-centre study. All GGOs were identified by IU. The mean size and depth were 14.1 ± 0.5 and 4.8 ± 0.3 mm, respectively. Six (40%) lesions had hyperechoic patterns, 9 (60%) had mixed echogenicity where the hyperechoic patterns were irregularly mixed with hypoechoic patterns. The final diagnoses included 2 (15%) atypical adenomatous hyperplasia; 2 (15%) adenocarcinomas in situ; 3 (23%) minimally invasive adenocarcinomas and 6 (46%) invasive adenocarcinomas.</p><p><strong>Conclusions: </strong>The results of our study showed that IU could safely and effectively detect GGOs.</p>","PeriodicalId":13621,"journal":{"name":"Interactive cardiovascular and thoracic surgery","volume":"35 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9749129/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10484571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Retrograde type A aortic dissection: a different evil.","authors":"Ana Lopez-Marco, Benjamin Adams, Aung Ye Oo","doi":"10.1093/icvts/ivac264","DOIUrl":"https://doi.org/10.1093/icvts/ivac264","url":null,"abstract":"<p><p>Retrograde type A aortic dissection (RTAAD) can be spontaneous or secondary to the instrumentation of the descending and thoraco-abdominal aorta. It has anatomical differences compared to antegrade type A aortic dissection that impact the management and prognosis. Treatment is not standardized. We report our approach to spontaneous RTAAD in our institution between 2018 and 2022 (n = 15). The mean age was 60.1 years and 93% were male. Aortic valve, coronary arteries and supra-aortic trunks were spared by the dissection in 80% of the cases; distal extension to iliacs was common and lower limb malperfusion was present in 4 cases (27%). The ascending aorta was dilated at presentation in 60% of the cases. Emergency surgery with arch/FET replacement was offered to 11 patients (73%); 3 patients (20%) received a limited proximal aortic repair; 1 patient was treated conservatively. Overall mortality was 47% (100% for limited proximal repair and 22% for those who received arch/FET). We advocate for aggressive treatment of RTAAD excluding the primary entry tear to prevent immediate- and mid-term complications.</p>","PeriodicalId":13621,"journal":{"name":"Interactive cardiovascular and thoracic surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9642331/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40673652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Viktoria H M Weixler, Kira Kuschnerus, Olga Romanchenko, Stanislav Ovroutski, Mi-Young Cho, Felix Berger, Matthias Sigler, Nicodème Sinzobahamvya, Joachim Photiadis, Peter Murin
{"title":"Mid-term performance of decellularized equine pericardium in congenital heart surgery.","authors":"Viktoria H M Weixler, Kira Kuschnerus, Olga Romanchenko, Stanislav Ovroutski, Mi-Young Cho, Felix Berger, Matthias Sigler, Nicodème Sinzobahamvya, Joachim Photiadis, Peter Murin","doi":"10.1093/icvts/ivac269","DOIUrl":"10.1093/icvts/ivac269","url":null,"abstract":"<p><strong>Objective: </strong>The aim was to report mid-term performance of decellularized equine pericardium used for repair of various congenital heart defects in the pediatric population.</p><p><strong>Methods: </strong>A retrospective review of all patients undergoing patch implantation between 2016 - 2020 was performed. Patch quality, surgical handling, hemostasis and early patch-related complications were studied on all patients. Mid-term performance was observed in patients with ≥12 months follow-up and intact patch at discharge (without reoperation/stent implantation).</p><p><strong>Results: </strong>A total of 201 patients with median age of 2.5 years [interquartile range (IQR): 0.6-6.5] underwent 207 procedures at 314 implant locations. The patch was used in following numbers/locations: 171 for pulmonary artery (PA) augmentation, 36 for aortic repair, 35 for septal defect closure, 22 for valvular repair and 50 at other locations. Early/30-day mortality was 6.5%. Early patch-related reoperations/stent implantations occurred in 28 locations (8.9%). No patch-related complications were noted except for bleeding from implant site in three locations (1%). Follow-up ≥ 12 months was available for 132 patients/200 locations. During a median follow-up of 29.7 months [IQR: 20.7-38.3], 53 patch-related reoperations/catheter reinterventions occurred (26.5%) with the majority in PA position (88.7%, 47/53). Overall 12- and 24-months freedom from patch-related reoperation/catheter reintervention per location was 91.5% (95% CI: 86.7%-94.6%) and 85.2% (95% CI: 78.9%-89.6%) respectively.</p><p><strong>Conclusion: </strong>Decellularized equine pericardium used for repair of various congenital heart defects showed acceptable mid-term performance. Reoperation/reintervention rates were in a range as observed with other xenogeneic materials previously reported articles, occurring most frequently after PA augmentation.</p>","PeriodicalId":13621,"journal":{"name":"Interactive cardiovascular and thoracic surgery","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2022-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11639235/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9104794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nawin L Ramdat Misier, Yannick J H J Taverne, Mathijs S van Schie, Rohit K Kharbanda, Wouter J van Leeuwen, Janneke A E Kammeraad, Ad J J C Bogers, Natasja M S de Groot
{"title":"Unravelling early sinus node dysfunction after pediatric cardiac surgery: a pre-existing arrhythmogenic substrate.","authors":"Nawin L Ramdat Misier, Yannick J H J Taverne, Mathijs S van Schie, Rohit K Kharbanda, Wouter J van Leeuwen, Janneke A E Kammeraad, Ad J J C Bogers, Natasja M S de Groot","doi":"10.1093/icvts/ivac262","DOIUrl":"10.1093/icvts/ivac262","url":null,"abstract":"<p><p>Early post-operative sinus node dysfunction (SND) is common in paediatric patients undergoing surgical correction of congenital heart defects (CHD). At present, the pathophysiology of these arrhythmias is incompletely understood. In this case series, we present three paediatric patients in whom we performed intraoperative epicardial mapping and who developed early post-operative SND. All patients had either an inferior or multiple sinoatrial node (SAN) exit sites, in addition to extensive conduction disorders at superior and inferior right atrium. Our findings contribute to the hypothesis that pre-existing alterations in SAN exit sites in combination with atrial conduction disorders may predispose paediatric patients with CHD for early post-operative SND. Such insights in the development of arrhythmias are crucial as it may be the first step in identifying high-risk patients.</p>","PeriodicalId":13621,"journal":{"name":"Interactive cardiovascular and thoracic surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/21/08/ivac262.PMC10021071.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9131631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Editorial: looking for the best treatment of bicuspid aortic valves.","authors":"Ruggero De Paulis","doi":"10.1093/icvts/ivac253","DOIUrl":"10.1093/icvts/ivac253","url":null,"abstract":"","PeriodicalId":13621,"journal":{"name":"Interactive cardiovascular and thoracic surgery","volume":"35 5","pages":""},"PeriodicalIF":1.6,"publicationDate":"2022-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9583848/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33504489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clément Dubost, Jacques Tomasi, Antoine Ducroix, Kevin Pluchon, Pierre Escrig, Olivier Fouquet, Arthur Aupart, Alain Mirza, Imen Fellah, Eric Bezon, Christophe Baufreton, Jean Marc El Arid, Jean-Christian Roussel, Jean-Philippe Verhoye, Thomas Senage
{"title":"AORTLANTIC: French registry of aortic valve-sparing root replacement, preliminary multicentre results from western France.","authors":"Clément Dubost, Jacques Tomasi, Antoine Ducroix, Kevin Pluchon, Pierre Escrig, Olivier Fouquet, Arthur Aupart, Alain Mirza, Imen Fellah, Eric Bezon, Christophe Baufreton, Jean Marc El Arid, Jean-Christian Roussel, Jean-Philippe Verhoye, Thomas Senage","doi":"10.1093/icvts/ivac240","DOIUrl":"https://doi.org/10.1093/icvts/ivac240","url":null,"abstract":"<p><strong>Objectives: </strong>Aortic root aneurysms often affect younger patients in whom valve-sparing surgery is challenging. Among current techniques, aortic valve-sparing root replacement described by Tirone David has shown encouraging results. The AORTLANTIC registry was instituted for a multicentre long-term evaluation of this procedure. The current initial study evaluates the hospital outcomes of the procedure.</p><p><strong>Methods: </strong>This is a retrospective study of patients operated between 1 January 2004 and 31 December 2020 in 6 hospitals in western France. All study data were recorded in the national digital database of the French Society of Cardiac Surgery: EPICARD.</p><p><strong>Results: </strong>A total of 524 consecutive patients with a mean age of 53 (15.1) years underwent surgery. 13% (n = 68) of patients presented with acute aortic dissection, 16.5% (n = 86) had associated connective tissue pathology and 7.3% (n = 37) had bicuspid aortic valves. Preoperative aortic regurgitation (AR) ≥2/4 was present in 65.3% (n = 341) of patients. Aortic valvuloplasty was required in 18.6% (n = 95) of patients. At discharge, 92.8% (n = 461) of patients had no or 1/4 AR. The stroke rate was 1.9% (n = 10). Intra-hospital mortality was 1.9% (n = 10).</p><p><strong>Conclusions: </strong>The AORTLANTIC registry includes 6 centres in western France with >500 patients. Despite numerous complex cases (acute aortic dissections, bicuspid aortic valves, preoperative AR), aortic valve-sparing root replacement has a low intra-hospital mortality. The initial encouraging results of this multicentre study warrant further long-term evaluation by future studies.</p>","PeriodicalId":13621,"journal":{"name":"Interactive cardiovascular and thoracic surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a7/e9/ivac240.PMC9550271.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40381251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Thierry Carrel, Juri Sromicki, Martin Schmiady, Raed Aser, Ahmed Ouda, Paul Robert Vogt
{"title":"Aortic wrapping is life-saving in high-risk acute aortic dissection and intramural haematoma.","authors":"Thierry Carrel, Juri Sromicki, Martin Schmiady, Raed Aser, Ahmed Ouda, Paul Robert Vogt","doi":"10.1093/icvts/ivac254","DOIUrl":"https://doi.org/10.1093/icvts/ivac254","url":null,"abstract":"<p><p>Aortic wrapping is a controversial repair in patients presenting with acute type A aortic dissection or intramural haematoma, but this method may be a potential alternative to medical treatment or conventional repair in patients aged >80 years and in those presenting with prohibitive co-morbidities such as stroke, circulatory collapse, full oral anticoagulation with the last generation drugs. We report on 5 high-risk and/or patients over 80 years who received external aortic wrapping with or without cardiopulmonary bypass during the last 18 months. All survived the procedure and could be extubated early postoperatively. No patient remained on the intensive care longer than 2 days and all were discharged without additional complications. Postoperative radiological control was acceptable and no patient had any new aortic event up to 18 months postoperatively.</p>","PeriodicalId":13621,"journal":{"name":"Interactive cardiovascular and thoracic surgery","volume":"35 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9580516/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33492579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A word to the wise ….","authors":"Augusto D'Onofrio, Gino Gerosa","doi":"10.1093/icvts/ivac252","DOIUrl":"https://doi.org/10.1093/icvts/ivac252","url":null,"abstract":"We read with interest Dr. David’s commentary [1] about our recently published paper entitled ‘Transapical beating heart mitral valve repair versus conventional surgery: a propensity-matched study’ [2]. We would like to clarify some aspects that in our opinion are crucial. We are afraid that Dr. David missed one of the key points of our study that, despite its intrinsic limitations that limit the generalizability of our results, shows that in patients with favourable anatomy (prolapse of the P2 segment), there seem to be no differences in terms of freedom from recurrent mitral regurgitation and of freedom from reoperation. Therefore, despite the worse outcomes in the overall population (this is what Dr. David refers to in his commentary), in well-selected patients, transapical beating heart mitral valve repair with neochords implantation (NC) provides similar outcomes to conventional surgery up to 5 years. We respectfully disagree with Dr. David when he states that NC should be selected in inoperable patients only after excluding the feasibility of a transcatheter Mitraclip (Abbott laboratories, Chicago, IL, USA). There are no data supporting this statement since there are no studies comparing NC and Mitraclip. However, in a recently published article about 100 NC patients with 5-year follow-up (including technical and patient-selection learning curves), we found an incidence of reoperation and of severe mitral regurgitation (MR), in patients with favourable anatomy, of 14.7% and 14.7%, respectively [3]. On the other hand, in the EVEREST-II study (therefore in highly selected patients), rates of reoperation and 3+ or 4+ MR at 5 years in the percutaneous repair group were 43% and 19%, respectively [4]. Noteworthy, 3+ and 4+ MR do not include moderate MR but only moderate– severe and severe MR and also, the EVEREST-II included both degenerative and functional MR. Another important aspect to consider is that so far over 100,000 patients over a 17-year period have been treated with Mitraclip, demonstrating the perseverance of our interventional cardiology colleagues (and some surgeons) that, despite the poor initial outcomes of this procedure, have worked to transform a suboptimal conventional surgical procedure (edge to edge with no annular stabilization) into a successful microinvasive alternative, optimizing technology, technique and patient selection [5, 6]. Meanwhile, NC procedures have been performed only in 1000 patients and we are still using the first-generation device. There are still many aspects that may be improved in order to achieve better results. We certainly agree that conventional surgery so far provides unsurpassed optimal outcomes for degenerative MR, especially if performed in high-volume centres and by highly committed surgeons or, even better, by world-recognized Masters as Dr. David. His results are impressive but the real world is a different thing and such numbers are difficult to replicate. The truth is that not all tennis ","PeriodicalId":13621,"journal":{"name":"Interactive cardiovascular and thoracic surgery","volume":"35 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9585944/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33492580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Paige Newell, Richard Tartarini, Sameer Hirji, Morgan Harloff, Siobhan McGurk, Olena Cherkasky, Tsuyoshi Kaneko
{"title":"Observed versus expected morbidity and mortality in patients undergoing mitral valve repair.","authors":"Paige Newell, Richard Tartarini, Sameer Hirji, Morgan Harloff, Siobhan McGurk, Olena Cherkasky, Tsuyoshi Kaneko","doi":"10.1093/icvts/ivac241","DOIUrl":"https://doi.org/10.1093/icvts/ivac241","url":null,"abstract":"<p><strong>Objectives: </strong>Mitral valve repair (MVP) is the gold standard treatment for degenerative mitral regurgitation. With the expansion of transcatheter technologies, this study compares the outcome of MVP in low-risk and non-low-risk patients to serve as a benchmark.</p><p><strong>Methods: </strong>This retrospective, single-institution study examined all patients who underwent MVP for primary mitral regurgitation from 2005 to 2018. Patients were stratified into 2 risk categories: low-risk [Society of Thoracic Surgeons (STS) Predicted Risk of Mortality (STS-PROM) ≤2%] and non-low risk (STS-PROM > 2% or age > 75), with a subgroup of very low risk (STS-PROM ≤1%, age <75).</p><p><strong>Results: </strong>A total of 1207 patients were included, and 1053 patients were classified as low risk and 154 as non-low risk. The non-low-risk group was significantly older, more likely to be female, and had a higher comorbidity burden than the low-risk group (all P < 0.01). For the low-risk group, the observed-to-expected (O:E) STS mortality ratio was 0.4 and the composite morbidity and mortality ratio was 0.6, whereas for the non-low risk, the O:E mortality was 1.5 and the composite morbidity and mortality was 0.9. When the subgroup of very low-risk group was assessed, the mortality O:E ratio was 0.</p><p><strong>Conclusions: </strong>The observed composite morbidity and mortality of patients undergoing MVP were persistently lower in low-risk patients, mainly driven by the very low-risk group. The excellent outcome of MVP in low-risk patients should be validated on a national level to determine how transcatheter technologies can be utilized in these patients.</p>","PeriodicalId":13621,"journal":{"name":"Interactive cardiovascular and thoracic surgery","volume":"35 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9553224/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33492735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anatol Prinzing, Johannes Böhm, Konstantinos Sideris, Keti Vitanova, Rüdiger Lange, Markus Krane
{"title":"AVNeo improves early haemodynamics in regurgitant bicuspid aortic valves compared to aortic valve repair.","authors":"Anatol Prinzing, Johannes Böhm, Konstantinos Sideris, Keti Vitanova, Rüdiger Lange, Markus Krane","doi":"10.1093/icvts/ivac226","DOIUrl":"10.1093/icvts/ivac226","url":null,"abstract":"<p><strong>Objectives: </strong>Calcified or fibrotic cusps in patients with bicuspid aortic valves and aortic regurgitation complicate successful aortic valve (AV)-repair. Aortic valve neocuspidization (AVNeo) with autologous pericardium offers an alternative treatment to prosthetic valve replacement. We compared patients with regurgitant bicuspid valves undergoing AV-repair or AVNeo.</p><p><strong>Methods: </strong>We retrospectively analysed patients with regurgitant bicuspid valves undergoing AV-repair or AVNeo. We focused on residual regurgitation, pressure gradients and effective orifice area, determined preoperatively and at discharge.</p><p><strong>Results: </strong>AV-repair was performed in 61 patients (mean age: 43.2 ± 11.3 years) and AVNeo in 22 (45.7 ± 14.1). Prior to the operation patients of the AV-repair group showed severe regurgitation in 38 cases (62.3%) and moderate in 23 (37.6%); in the AVNeo group, all patients exhibited severe regurgitation. Postoperatively, 57 patients (93.4%) patients had no or mild regurgitation after AV-repair and 21 (95.4%) after AVNeo. In AVNeo-patients, peak (10.6 ± 3.1 mmHg vs 22.7 ± 11 mmHg, P< 0.001) and mean pressure gradients (5.9 ± 2 mmHg vs 13.8 ± 7.3 mmHg, P < 0.001) were significantly lower and the orifice area significantly larger (2.9 ± 0.8 cm2 vs 1.9 ± 0.7 cm2, P < 0.001) compared to repair.</p><p><strong>Conclusions: </strong>Compared to AV-repair, patients AVNeo showed lower mean pressure gradients and larger orifice areas at discharge. The functional result was not different.</p>","PeriodicalId":13621,"journal":{"name":"Interactive cardiovascular and thoracic surgery","volume":"35 5","pages":""},"PeriodicalIF":1.6,"publicationDate":"2022-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ed/ec/ivac226.PMC9615556.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33439789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}