Infectious Disease Reports最新文献_第10页

Streptococcus intermedius Brain Abscess with Lung Abscess and Aortic Valve Endocarditis: A Case Report and Literature Review. 中间链球菌脑脓肿伴肺脓肿和主动脉瓣心内膜炎：病例报告和文献综述。

IF 3.4

Infectious Disease Reports Pub Date : 2023-08-11 DOI: 10.3390/idr15040045

Francesca Gavaruzzi, Pierangelo Chinello, Giuseppe Cucinotta, Gianluigi Oliva, Alessandro Capone, Guido Granata, Samir Al Moghazi, Emanuela Caraffa, Fabrizio Taglietti

引用次数: 0

HIV-1 Low-Frequency Variants Identified in Antiretroviral-Naïve Subjects with Virologic Failure after 12 Months of Follow-Up in Panama. 在巴拿马随访12个月后病毒学失败的Antiretroviral-Naïve受试者中发现HIV-1低频变异

IF 3.2

Infectious Disease Reports Pub Date : 2023-08-01 DOI: 10.3390/idr15040044

Ambar Moreno, Claudia González, Jessica Góndola, Oris Chavarría, Alma Ortiz, Jorge Castillo, Juan Castillo Mewa, Juan Miguel Pascale, Alexander Augusto Martínez

{"title":"HIV-1 Low-Frequency Variants Identified in Antiretroviral-Naïve Subjects with Virologic Failure after 12 Months of Follow-Up in Panama.","authors":"Ambar Moreno, Claudia González, Jessica Góndola, Oris Chavarría, Alma Ortiz, Jorge Castillo, Juan Castillo Mewa, Juan Miguel Pascale, Alexander Augusto Martínez","doi":"10.3390/idr15040044","DOIUrl":"https://doi.org/10.3390/idr15040044","url":null,"abstract":"Low-frequency mutations associated with drug resistance have been related to virologic failure in subjects with no history of pre-treatment and recent HIV diagnosis. In total, 78 antiretroviral treatment (ART)-naïve subjects with a recent HIV diagnosis were selected and followed by CD4+ T lymphocytes and viral load tests to detect virologic failure. We sequenced the basal samples retrospectively using next-generation sequencing (NGS), looking for low-frequency mutations that had not been detected before using the Sanger sequencing method (SSM) and describing the response to ART. Twenty-two subjects developed virologic failure (VF), and thirteen of them had at least one drug-resistance mutation associated with Reverse Transcriptase Inhibitors (RTI) and Protease Inhibitors (PIs) at frequency levels ≤ 1%, not detected previously in their basal genotyping test. No resistance mutations were observed to Integrase Strand Transfer Inhibitors (INSTIs). We identified a possible cause of VF in ART-naïve subjects with low-frequency mutations detected. To our knowledge, this is the first evaluation of pre-existing drug resistance for HIV-1 minority variants carried out on ART-naïve people living with HIV/AIDS (PLWHA) by analyzing the HIV-1 pol gene using NGS in the country.","PeriodicalId":13579,"journal":{"name":"Infectious Disease Reports","volume":"15 4","pages":"436-444"},"PeriodicalIF":3.2,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454674/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10158397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

SARS-CoV-2 Infection Increases the Risk of Muscle Injury in Professional Male Soccer Players-A Retrospective Analysis of the Italian and Spanish Major Leagues. SARS-CoV-2感染增加职业男子足球运动员肌肉损伤的风险——对意大利和西班牙大联盟的回顾性分析

IF 3.2

Infectious Disease Reports Pub Date : 2023-07-26 DOI: 10.3390/idr15040043

Sandra Miccinilli, Marco Bravi, Giorgio Conti, Federica Bressi, Silvia Sterzi, Fabio Santacaterina, Massimo Ciccozzi

{"title":"SARS-CoV-2 Infection Increases the Risk of Muscle Injury in Professional Male Soccer Players-A Retrospective Analysis of the Italian and Spanish Major Leagues.","authors":"Sandra Miccinilli, Marco Bravi, Giorgio Conti, Federica Bressi, Silvia Sterzi, Fabio Santacaterina, Massimo Ciccozzi","doi":"10.3390/idr15040043","DOIUrl":"https://doi.org/10.3390/idr15040043","url":null,"abstract":"A retrospective cohort study on professional soccer players from the Serie A and LaLiga was conducted to investigate the correlation between SARS-CoV-2 infection and muscle injuries. Players were divided into two groups based on whether they contracted the SARS-CoV-2 infection (C+) or not (C-) during the 2020/2021 season. In the 2019-2020 season, both championships showed a similar number of muscular injuries (MI) between C+ and C- (Serie A: p = 0.194; 95% CI: -0.044 to 0.215, LaLiga p = 0.915; 95% CI: -0.123 to 0.137). In the 2020-2021 season, C+ had a significantly higher number of MI compared to C- in both championships (Serie A: p < 0.05; 95% CI 0.731 to 1.038; LaLiga: p < 0.05; 95% CI: 0.773 to 1.054). Multiple linear regression analysis confirmed that belonging to C+ in the season 2020/2021 was the variable that most strongly influenced the probability of having a muscle injury. Survival analysis revealed a hazard ratio of 3.73 (95% CI 3.018 to 4.628) and of 5.14 (95% CI 3.200 to 8.254) for Serie A and LaLiga respectively. We found an association between SARS-CoV-2 infection and increased risk of muscle injury, emphasizing the importance of carefully considering the infection in the decision-making process for returning to sport. Therefore, SARS-CoV-2 infection should be judged as a real injury requiring specific assessment and training programs.","PeriodicalId":13579,"journal":{"name":"Infectious Disease Reports","volume":"15 4","pages":"425-435"},"PeriodicalIF":3.2,"publicationDate":"2023-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454539/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10158399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intraparenchymal Lung Abscess Complicating a Primary COVID-19 Infection in a Patient with Waldenström's Macroglobulinemia: A Case Report. 肺实质内脓肿合并原发性COVID-19感染Waldenström巨球蛋白血症1例

IF 3.2

Infectious Disease Reports Pub Date : 2023-07-10 DOI: 10.3390/idr15040039

Panagiotis F Mavroudis, Lemonia Velentza, Panagiotis G Sfyridis, Styliani Papantoniou, Georgios Kranidiotis, Efthymia Giannitsioti, Alexandra Stamati, Dimitrios Schizas, Styliani Gerakari, Emmanouil I Kapetanakis

{"title":"Intraparenchymal Lung Abscess Complicating a Primary COVID-19 Infection in a Patient with Waldenström's Macroglobulinemia: A Case Report.","authors":"Panagiotis F Mavroudis, Lemonia Velentza, Panagiotis G Sfyridis, Styliani Papantoniou, Georgios Kranidiotis, Efthymia Giannitsioti, Alexandra Stamati, Dimitrios Schizas, Styliani Gerakari, Emmanouil I Kapetanakis","doi":"10.3390/idr15040039","DOIUrl":"https://doi.org/10.3390/idr15040039","url":null,"abstract":"Intraparenchymal lung abscess development associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is a rare complication, with only half a dozen primary cases having been reported in the literature. We present the case of a patient with Waldenström's macroglobulinemia who developed a lung abscess subsequent to a primary SARS-CoV-2 infection. We present a 63-year-old male patient with SARS-CoV-2 infection and a history of Waldenström's macroglobulinemia who developed a cavitating intraparenchymal lung abscess with an air-fluid level in his right lower lobe two weeks following admission to hospital. The patient became septic and developed acute respiratory failure requiring mechanical ventilation and intensive care. He was managed with broad-spectrum antibiotic therapy and aspiration drainage, but unfortunately due to his severe clinical condition died 20 days after his initial admission. The development of a lung abscess in patients with COVID-19, although rare, can be quite compromising and even prove fatal, especially in immunocompromised patients. Clinicians should be aware of this potential complication.","PeriodicalId":13579,"journal":{"name":"Infectious Disease Reports","volume":"15 4","pages":"386-391"},"PeriodicalIF":3.2,"publicationDate":"2023-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366762/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9874671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Detection of Mutations and Genotyping of Drug-Resistant Mycobacterium tuberculosis Strains Isolated from Patients in the Rural Eastern Cape Province. 东开普省农村地区患者结核分枝杆菌耐药菌株突变检测及基因分型分析。

IF 3.2

Infectious Disease Reports Pub Date : 2023-07-10 DOI: 10.3390/idr15040041

Lindiwe M Faye, Mojisola C Hosu, Selien Oostvogels, Anzaan Dippenaar, Robin M Warren, Ncomeka Sineke, Sandeep Vasaikar, Teke Apalata

{"title":"The Detection of Mutations and Genotyping of Drug-Resistant Mycobacterium tuberculosis Strains Isolated from Patients in the Rural Eastern Cape Province.","authors":"Lindiwe M Faye, Mojisola C Hosu, Selien Oostvogels, Anzaan Dippenaar, Robin M Warren, Ncomeka Sineke, Sandeep Vasaikar, Teke Apalata","doi":"10.3390/idr15040041","DOIUrl":"https://doi.org/10.3390/idr15040041","url":null,"abstract":"Drug-resistant tuberculosis (DR-TB) is still a major public health concern in South Africa. Mutations in M. tuberculosis can cause varying levels of phenotypic resistance to anti-TB medications. There have been no prior studies on gene mutations and the genotyping of DR-TB in the rural Eastern Cape Province; hence, we aimed to identify DR-TB mutations, genetic diversity, and allocated lineages among patients in this area. Using Xpert® MTB/RIF, we assessed the rifampin resistance of sputum samples collected from 1157 patients suspected of having tuberculosis. GenoType MTBDR plus VER 2.0 was used for the detection of mutations causing resistance to anti-TB medications. The next step was to spoligotype 441 isolates. The most prevalent rifampin resistance-conferring mutations were in rpoB codon S531L in INH-resistant strains; the katG gene at codon S315TB and the inhA gene at codon C-15TB had the most mutations; 54.5% and 24.7%, respectively. In addition, 24.6% of strains showed mutations in both the rpoB and inhA genes, while 69.9% of strains showed mutations in both the katG and rpoB genes. Heteroresistance was seen in 17.9% of all cases in the study. According to spoligotyping analysis, Beijing families predominated. Investigation of the evolutionary lineages of M. tuberculosis isolates can be carried out using the information provided by the study's diversity of mutations. In locations wherein these mutations have been discovered, decision-making regarding the standardization of treatment regimens or individualized treatment may be aided by the detection frequency of rpoB, katG, and inhA mutations in various study areas.","PeriodicalId":13579,"journal":{"name":"Infectious Disease Reports","volume":"15 4","pages":"403-416"},"PeriodicalIF":3.2,"publicationDate":"2023-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366782/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9874669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Predictors of Quality of Life in HIV-Infected Persons from Mozambique: The Dual Role of Schooling. 莫桑比克艾滋病毒感染者生活质量的预测因素:学校教育的双重作用。

IF 3.2

Infectious Disease Reports Pub Date : 2023-07-10 DOI: 10.3390/idr15040040

Jorge Lufiande, Susana Silva, Ana Catarina Reis, Marina Prista Guerra

{"title":"Predictors of Quality of Life in HIV-Infected Persons from Mozambique: The Dual Role of Schooling.","authors":"Jorge Lufiande, Susana Silva, Ana Catarina Reis, Marina Prista Guerra","doi":"10.3390/idr15040040","DOIUrl":"https://doi.org/10.3390/idr15040040","url":null,"abstract":"Increasing quality of life (QoL) is both an end in itself and a means to optimize the impact of treatment in HIV-infected persons. Possibly due to cultural and social influences, the predictors of QoL vary across studies, highlighting the importance of studying specific populations. In the present study, we aimed to determine the sociodemographic (age, sex and schooling, or number of years at school) and psychosocial correlates (meaning in life, social support, positive and negative affects) of QoL in HIV-infected persons living in Mozambique, a country with a high prevalence of HIV but also with well-structured strategies to fight the disease. To that end, we made correlational analyses followed by regression models and examined potential mediation processes among predictors. All correlates were relevant except for sex. Meaning in life was the strongest predictor, while social support was the weakest. Schooling was both directly and indirectly related with QoL-in the latter case, it was mediated by meaning in life, social support and positive affect. Our findings suggest that investments in education may be highly rewarding to Mozambicans, and that satisfying needs for self-actualization and purpose may be more urgent than improving social connections.","PeriodicalId":13579,"journal":{"name":"Infectious Disease Reports","volume":"15 4","pages":"392-402"},"PeriodicalIF":3.2,"publicationDate":"2023-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366898/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10251565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enterobius vermicularis Related Acute Appendicitis: A Case Report and Review of the Literature. 蚓状肠虫相关急性阑尾炎1例报告及文献复习。

IF 3.2

Infectious Disease Reports Pub Date : 2023-07-10 DOI: 10.3390/idr15040042

Shabnam Chhetri, Ahmed Hamood Al Mamari, Mahmood Mausd Al Awfi, Nasser Humaid Nasser Al Khaldi, Nibras Mejbel Abed, Nenad Pandak, Faryal Khamis, Zakariya Al Balushi, Rashid Mohammed Khamis Alalawi, Sultan Al Lawati, Muna Ba'Omar, Nasser Shukaili, Seif Al-Abri

引用次数: 0

Severe Typhoid Fever Complicated by Superior Mesenteric and Splenic Vein Thrombosis. 重症伤寒并发肠系膜上静脉及脾静脉血栓。

IF 3.2

Infectious Disease Reports Pub Date : 2023-07-08 DOI: 10.3390/idr15040038

Piero Veronese, Marco Pappalardo, Valentina Maffini, Monica Rubini, Alessandra Giacometti, Maria Beatrice Ruozi, Simone Cella, Icilio Dodi

引用次数: 0

The Medical Community's Role in Communication Strategies during Health Crises-Perspective from European Union of Medical Specialists (UEMS). 健康危机期间医学界在沟通策略中的角色——来自欧洲医学专家联盟(UEMS)的视角。

IF 3.2

Infectious Disease Reports Pub Date : 2023-07-03 DOI: 10.3390/idr15040037

Ilia Nadareishvili, Theodore Bazas, Nicola Petrosillo, Vojko Berce, John Firth, Armando Mansilha, Mihaela Leventer, Alessandra Renieri, Mauro Zampolini, Vassilios Papalois

{"title":"The Medical Community's Role in Communication Strategies during Health Crises-Perspective from European Union of Medical Specialists (UEMS).","authors":"Ilia Nadareishvili, Theodore Bazas, Nicola Petrosillo, Vojko Berce, John Firth, Armando Mansilha, Mihaela Leventer, Alessandra Renieri, Mauro Zampolini, Vassilios Papalois","doi":"10.3390/idr15040037","DOIUrl":"https://doi.org/10.3390/idr15040037","url":null,"abstract":"The COVID-19 pandemic was complicated by the spread of false information leading to what became widely called an \"infodemic\". The present opinion paper was written by an ad hoc international team united under the European Union of Medical Specialists (UEMS) umbrella and reflects the organizations' effort to contribute to the resolution of these issues, by highlighting and reflecting on them and by suggesting the medical community's necessary activities resulting in the formulation of effective future communication strategies. The importance of physicians' and other health workers' role and mission as educators and leaders in communities in critical situations should be reassessed and upgraded. We need to equip future doctors with strong and sustainable leadership and communication skills through relevant undergraduate and postgraduate education programs, in order that compliance with preventive medical advice is increased. To avoid possible politically and otherwise biased communication in health crises of the future, European nations should establish independent advisory bodies providing evidence-based advice and participate in communication campaigns. Medical and other health professional organizations should build organizational and personal capacities of their members to enable them to reliably inform and adequately educate governments, populations, civic society, employers' and employees' organizations, schools and universities, and other stakeholders.","PeriodicalId":13579,"journal":{"name":"Infectious Disease Reports","volume":"15 4","pages":"370-376"},"PeriodicalIF":3.2,"publicationDate":"2023-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366824/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9874668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

La Crosse Virus Circulation in Virginia, Assessed via Serosurveillance in Wildlife Species. 通过野生动物血清监测评估弗吉尼亚州拉克罗斯病毒的传播。

IF 3.2

Infectious Disease Reports Pub Date : 2023-06-30 DOI: 10.3390/idr15040036

Lindsey R Faw, Jennifer Riley, Gillian Eastwood

{"title":"La Crosse Virus Circulation in Virginia, Assessed via Serosurveillance in Wildlife Species.","authors":"Lindsey R Faw, Jennifer Riley, Gillian Eastwood","doi":"10.3390/idr15040036","DOIUrl":"https://doi.org/10.3390/idr15040036","url":null,"abstract":"Mosquito-borne La Crosse virus (LACV; family: Peribunyaviridae) is the leading cause of pediatric arboviral encephalitis in the United States, with clinical cases generally centered in the Midwest and Appalachian regions. Incidence of LACV cases in Appalachian states has increased, such that the region currently represents the majority of reported LACV cases in the USA. The amount of reported LACV cases from Virginia, however, is minimal compared to neighboring states such as North Carolina, West Virginia, and Tennessee, and non-Appalachian regions of Virginia are understudied. Here we examine the hypothesis that LACV is circulating widely in Virginia, despite a low clinical case report rate, and that the virus is circulating in areas not associated with LACV disease. In this study, we screened local mammalian wildlife in northwestern counties of Virginia using passive surveillance via patients submitted to wildlife rehabilitation centers. Blood sera (527 samples; 9 species, 8 genera) collected between October 2019 and December 2022 were screened for neutralizing antibodies against LACV, indicating prior exposure to the virus. We found an overall LACV seroprevalence of 1.90% among all wild mammals examined and reveal evidence of LACV exposure in several wild species not generally associated with LACV, including eastern cottontails and red foxes, along with established reservoirs, eastern gray squirrels, although there was no serological evidence in chipmunks. These data indicate the circulation of LACV in Virginia outside of Appalachian counties, however, at a lower rate than reported for endemic areas within the state and in other states.","PeriodicalId":13579,"journal":{"name":"Infectious Disease Reports","volume":"15 4","pages":"360-369"},"PeriodicalIF":3.2,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366734/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10251567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0