{"title":"Inhaled Nitric Oxide Reduces Lung Injury During Cardiac Surgery With One-Lung Ventilation in an Experimental Pig Model.","authors":"Hiroshi Mitsuo, Tomoki Ushijima, Hikaru Uchiyama, Kensaku Matsuda, Takuya Nishijima, Masayuki Shimada, Yusuke Nakata, Noriko Fujimoto, Kunihiko Joo, Yusuke Ando, Tatsushi Onzuka, Satoshi Kimura, Hiromichi Sonoda, Akira Shiose","doi":"10.1177/15569845251405829","DOIUrl":"10.1177/15569845251405829","url":null,"abstract":"<p><strong>Objective: </strong>Minimally invasive cardiac surgery (MICS) may require one-lung ventilation (OLV) during minithoracotomy. One of the problems associated with MICS is postoperative unilateral pulmonary edema of the collapsed lung, which may be fatal. Several reports have demonstrated the effects of inhaled nitric oxide (NO) on lung ischemia-reperfusion injury. In this study, we created an in vivo pig model using cardiopulmonary bypass (CPB) and OLV, enabling us to compare bilateral lung injury at the same time point in the same individual. The aim of this study is to examine the effects of inhaled NO in a model that approximates MICS.</p><p><strong>Methods: </strong>Ten pigs were subjected to 3 h of CPB and OLV with clamping of the main pulmonary artery. The bilateral lungs of the pigs were categorized into 4 groups according to their ventilation status and the presence or absence of NO inhalation (<i>n</i> = 5 per group). Lungs were collected after the experiment, and inflammatory cytokine measurements and pathological evaluations were performed.</p><p><strong>Results: </strong>In the OLV group (group 1 vs 2), the levels of interleukin-6, interleukin-8, and myeloperoxidase in collapsed lung tissue increased, along with an increase in the number of apoptotic cells and exacerbation of pulmonary edema. In the collapsed lungs (group 2 vs 4), NO inhalation reduced the levels of interleukin-6 and myeloperoxidase, the number of apoptotic cells, and pulmonary edema.</p><p><strong>Conclusions: </strong>In an animal model using a combination of CPB and OLV, inhaled NO suppressed pulmonary edema and improved the exacerbated lung injury of collapsed lungs.</p>","PeriodicalId":13574,"journal":{"name":"Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery","volume":" ","pages":"56-63"},"PeriodicalIF":1.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146100120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Susana Fortich, Jennifer Den, Mathew Thomas, Roman Petrov
{"title":"Feasibility of Intraoperative Tissue Oxygen Saturation Imaging Using OXEI Technology During Robotic Esophagectomy: A Case Series.","authors":"Susana Fortich, Jennifer Den, Mathew Thomas, Roman Petrov","doi":"10.1177/15569845251401204","DOIUrl":"10.1177/15569845251401204","url":null,"abstract":"<p><strong>Objective: </strong>Esophageal cancer is a leading cause of cancer-related mortality, with a 5-year survival rate of 20%. Surgical resection remains the primary treatment for early and locally advanced disease. Anastomotic leak is a major concern, which significantly increases morbidity and mortality. Impaired conduit perfusion and tissue ischemia are key risk factors. This series describes the use of ELUXEO Oxygen Saturation Endoscopic Imaging (OXEI) technology (Fujifilm Healthcare Americas Corp, Lexington, MA, USA) to assess tissue oxygen saturation during esophagectomy.</p><p><strong>Methods: </strong>OXEI was used in 6 cases to evaluate conduit perfusion during esophagectomy procedures. Real-time hemoglobin oxygen saturation imaging identified ischemic areas, with StO<sub>2</sub> levels ranging from 17% in poorly perfused regions to 92% in well-perfused areas. OXEI findings were congruent with indocyanine green fluorescence imaging but avoided dye-related limitations.</p><p><strong>Results: </strong>OXEI technology offered a dye-free alternative that allowed real-time assessment of tissue oxygenation, facilitating accurate perfusion quantification. Its reproducibility without dye administration and limitations of tissue saturation or washout concerns added reliability, especially during long multistage procedures. In addition, OXEI has been shown to be consistent irrespective of distances from the targeted area, providing precise tissue saturation quantification throughout critical steps of esophagectomy. These findings highlight the potential of this technology as a valuable adjunct in esophageal surgery.</p><p><strong>Conclusions: </strong>The experience with ELUXEO technology in esophagectomy is promising. It provides a reliable, dye-free method for real-time perfusion assessment, potentially reducing the incidence of anastomotic leaks, preventing dye-associated complications, and improving surgical outcomes. Further studies are warranted to validate these findings in esophagectomies.</p>","PeriodicalId":13574,"journal":{"name":"Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery","volume":" ","pages":"48-55"},"PeriodicalIF":1.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13049211/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146105334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Viktoriia Tymoshenko, Aldo J Suria, Gianluca Dimonte, Sahra Tasdelen, Thomas Poschner, Kyle C Purrman, Siyavush Saidian, Martin Andreas
{"title":"Evaluating the Efficacy of Automated Suturing Technology for Bentall Procedures in a Passive Beating Heart Model.","authors":"Viktoriia Tymoshenko, Aldo J Suria, Gianluca Dimonte, Sahra Tasdelen, Thomas Poschner, Kyle C Purrman, Siyavush Saidian, Martin Andreas","doi":"10.1177/15569845251407558","DOIUrl":"10.1177/15569845251407558","url":null,"abstract":"<p><strong>Objective: </strong>The Bentall procedure is a well-established surgical technique for managing aortic root disease involving the ascending aorta and aortic valve. The use of automated suturing technology may facilitate ergonomic, reliable suture placement, especially in minimally invasive approaches. Here we present the results of a study to evaluate the feasibility of using automated suturing technology for Bentall procedures in an ex vivo porcine model using a passive beating heart simulator.</p><p><strong>Methods: </strong>This study included 20 ex vivo porcine hearts, divided into an automated suturing cohort (<i>n</i> = 10) and a manual suturing cohort (<i>n</i> = 10). A Bentall procedure was performed on each heart, with the subject automated suturing technology used in place of manual suturing in the first cohort. After the procedure, each heart was tested in a passive beating heart testing simulator under increasingly challenging hemodynamic conditions (80, 100, and 120 mm Hg); any fluid leakage at the proximal anastomosis was quantified. Data were analyzed using nonparametric statistical tests.</p><p><strong>Results: </strong>Overall, leakage from the proximal anastomosis increased with higher pressure and longer duration in both groups (<i>P</i> < 0.001). There was no statistically significant difference in leakage between the automated and manual suture cohorts (<i>P</i> > 0.05), indicating that the study technology appears to be feasible and effective for placing sutures in Bentall procedures. Correlation analysis indicated a moderate positive relationship between aortic pressure and leakage in both groups.</p><p><strong>Conclusions: </strong>The subject automated suturing technology demonstrated comparable performance to manual suturing in ex vivo Bentall procedures, with no significantly different leakage across a range of increasing aortic pressures.</p>","PeriodicalId":13574,"journal":{"name":"Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery","volume":" ","pages":"73-79"},"PeriodicalIF":1.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13049216/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146100194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The 10 Commandments for Oral Anticoagulation After Tissue Valve Replacement.","authors":"Severin Laengle, Alfred Kocher","doi":"10.1177/15569845261416466","DOIUrl":"10.1177/15569845261416466","url":null,"abstract":"","PeriodicalId":13574,"journal":{"name":"Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery","volume":" ","pages":"8-10"},"PeriodicalIF":1.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147305277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hugo Monteiro Neder Issa, Andres Parisi, Daniel Goubran, Marc Ruel
{"title":"The 10 Commandments of Robotic Bilateral Internal Thoracic Artery Harvesting.","authors":"Hugo Monteiro Neder Issa, Andres Parisi, Daniel Goubran, Marc Ruel","doi":"10.1177/15569845251350280","DOIUrl":"10.1177/15569845251350280","url":null,"abstract":"","PeriodicalId":13574,"journal":{"name":"Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery","volume":" ","pages":"511-516"},"PeriodicalIF":1.6,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12701903/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144527793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
John J Kelly, Brittany J Cannon, Grace J Wang, Nimesh D Desai
{"title":"How I Do It: Zone 2 Arch With Sequential Single-Branch TEVAR for Acute Type A Aortic Dissection.","authors":"John J Kelly, Brittany J Cannon, Grace J Wang, Nimesh D Desai","doi":"10.1177/15569845251352817","DOIUrl":"10.1177/15569845251352817","url":null,"abstract":"","PeriodicalId":13574,"journal":{"name":"Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery","volume":" ","pages":"533"},"PeriodicalIF":1.6,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12701908/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144626180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Transaortic Partial Septectomy via Right Anterior Minithoracotomy for Hypertrophic Obstructive Cardiomyopathy.","authors":"Oleksandr Babliak, Dmytro Babliak, Serhii Yatsuk","doi":"10.1177/15569845251382589","DOIUrl":"10.1177/15569845251382589","url":null,"abstract":"","PeriodicalId":13574,"journal":{"name":"Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery","volume":" ","pages":"596"},"PeriodicalIF":1.6,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145212598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luigi Marano, Sergii Girnyi, Tomasz Cwalinski, Marek Strzemski, Karol Polom, Mateusz Wilcowski, Jaroslaw Skokowski
{"title":"Precision Surgery: Robotic, Augmented Reality, and 3D-Printed Approaches to Complex Giant Hiatal Hernia With Mesenteroaxial Volvulus.","authors":"Luigi Marano, Sergii Girnyi, Tomasz Cwalinski, Marek Strzemski, Karol Polom, Mateusz Wilcowski, Jaroslaw Skokowski","doi":"10.1177/15569845251382590","DOIUrl":"10.1177/15569845251382590","url":null,"abstract":"","PeriodicalId":13574,"journal":{"name":"Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery","volume":" ","pages":"601-602"},"PeriodicalIF":1.6,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145212574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Natasha Valas, Aaron R Dezube, Michael Dezube, Virginia R Litle
{"title":"Effect of Geographic and Sociodemographic Factors on the Use of Robot-Assisted Versus Video-Assisted Lung Resection.","authors":"Natasha Valas, Aaron R Dezube, Michael Dezube, Virginia R Litle","doi":"10.1177/15569845251388986","DOIUrl":"10.1177/15569845251388986","url":null,"abstract":"<p><strong>Objective: </strong>Robot-assisted thoracoscopic (RATS) lung resection is a widely used treatment modality. We hypothesized that geographic and sociodemographic factors would affect trends in RATS use versus video-assisted thoracoscopic (VATS) for lung resection in the United States.</p><p><strong>Methods: </strong>Retrospective study of patients who underwent either RATS or VATS lung resection from 2016 to 2020 within the National Inpatient Sample. Cohorts were stratified by extent (lobectomy vs sublobar) and technique (RATS vs VATS) of resection and compared with respect to sociodemographic, hospital-level, and geographic factors.</p><p><strong>Results: </strong>From 2016 to 2020, 81,340 patients underwent lobectomy (35.8% vs 64.3% for RATS vs VATS) and 88,620 underwent sublobar resection (24.2% vs 75.8% for RATS vs VATS). RATS lung resection rates varied by year and geographic division (<i>P</i> < 0.05). The odds ratio (OR) of RATS for lobectomies (reference = East South Central) ranged from 1.64 (95% confidence interval [CI]: 1.35 to 2.0) for Pacific to 3.88 (95% CI: 3.23 to 4.67) for East North Central. For sublobar resection, they ranged from 1.64 (95% CI: 1.31 to 2.06) for Pacific to 3.27 (95% CI: 2.69 to 4.02) for South Atlantic. Race, ruralness, treatment year, age, admission status, hospital teaching status, and certain insurance types were independently associated with the odds of RATS lobectomy use (<i>P</i> < 0.05). Findings were similar for sublobar resection use, except for insurance status (<i>P</i> > 0.05) and hospital bed size (<i>P</i> < 0.05).</p><p><strong>Conclusions: </strong>Geographic division remained independently associated with the odds of RATS lung resection after adjusting for sociodemographic factors. The overall rates of RATS use ranged from 16.9% to 44.7% for lobectomy and from 11.5% to 30.6% for sublobar lung resection between geographic regions.</p>","PeriodicalId":13574,"journal":{"name":"Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery","volume":" ","pages":"585-592"},"PeriodicalIF":1.6,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145603874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"E-vita Open Neo Hybrid Stent Graft Implantation Technique.","authors":"Ryaan El-Andari, Michael C Moon","doi":"10.1177/15569845251364258","DOIUrl":"10.1177/15569845251364258","url":null,"abstract":"","PeriodicalId":13574,"journal":{"name":"Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery","volume":" ","pages":"532"},"PeriodicalIF":1.6,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12701896/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144952758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}