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Pharmacologic Treatment and Management of Coronavirus Disease 2019.
IF 6.1 3区 医学
Infectious disease clinics of North America Pub Date : 2025-03-14 DOI: 10.1016/j.idc.2025.02.004
Amy Hirsch Shumaker, Adarsh Bhimraj
{"title":"Pharmacologic Treatment and Management of Coronavirus Disease 2019.","authors":"Amy Hirsch Shumaker, Adarsh Bhimraj","doi":"10.1016/j.idc.2025.02.004","DOIUrl":"https://doi.org/10.1016/j.idc.2025.02.004","url":null,"abstract":"<p><p>Widespread vaccination, hybrid immunity, and reduced pathogenicity with circulating Omicron variants have decreased the rate of severe coronavirus disease 2019 (COVID-19) outcomes in the general population. Certain patients with COVID-19 remain at high risk for severe outcomes. Clinicians must individualize treatments based on expected benefits and relative harms for patients with mild-to-moderate COVID-19. Guideline-directed therapy for severe and critical COVID-19 has remained static over the last couple of years. Data on immunomodulatory agents have improved our understanding of the management of severe and critical COVID-19, yet uncertainty remains on the role and timing of these agents in the Omicron era.</p>","PeriodicalId":13562,"journal":{"name":"Infectious disease clinics of North America","volume":" ","pages":""},"PeriodicalIF":6.1,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143634002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical Manifestations of SARS-CoV-2 Infection in Immunocompetent Adults in the Era of Widespread Population Immunity and Omicron Sublineage Viruses.
IF 6.1 3区 医学
Infectious disease clinics of North America Pub Date : 2025-03-10 DOI: 10.1016/j.idc.2025.02.002
Alexander Shaffer, Eric A Meyerowitz
{"title":"Clinical Manifestations of SARS-CoV-2 Infection in Immunocompetent Adults in the Era of Widespread Population Immunity and Omicron Sublineage Viruses.","authors":"Alexander Shaffer, Eric A Meyerowitz","doi":"10.1016/j.idc.2025.02.002","DOIUrl":"https://doi.org/10.1016/j.idc.2025.02.002","url":null,"abstract":"<p><p>While most SARS-CoV-2 infections and reinfections in the era of widespread population immunity with omicron subsub-lineage variants are mild for immunocompetent individuals, any manifestation previously seen during the pandemic phase is still possible. COVID-19 may affect any organ system. Previous infections and prior vaccines protect against symptomatic future SARS-CoV-2 infections, though this protection wanes over time.</p>","PeriodicalId":13562,"journal":{"name":"Infectious disease clinics of North America","volume":" ","pages":""},"PeriodicalIF":6.1,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143604767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Themes and Challenges in Managing Musculoskeletal Infections.
IF 6.1 3区 医学
Infectious disease clinics of North America Pub Date : 2025-03-10 DOI: 10.1016/j.idc.2025.02.008
Laura K Certain
{"title":"Themes and Challenges in Managing Musculoskeletal Infections.","authors":"Laura K Certain","doi":"10.1016/j.idc.2025.02.008","DOIUrl":"https://doi.org/10.1016/j.idc.2025.02.008","url":null,"abstract":"","PeriodicalId":13562,"journal":{"name":"Infectious disease clinics of North America","volume":" ","pages":""},"PeriodicalIF":6.1,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143604770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adult Long Coronavirus Disease 2019: Definition, Prevalence Pathophysiology, and Clinical Manifestations.
IF 6.1 3区 医学
Infectious disease clinics of North America Pub Date : 2025-03-10 DOI: 10.1016/j.idc.2025.02.007
Ivette Emery, Clifford Rosen
{"title":"Adult Long Coronavirus Disease 2019: Definition, Prevalence Pathophysiology, and Clinical Manifestations.","authors":"Ivette Emery, Clifford Rosen","doi":"10.1016/j.idc.2025.02.007","DOIUrl":"https://doi.org/10.1016/j.idc.2025.02.007","url":null,"abstract":"<p><p>Long coronavirus disease 2019 (COVID-19) is a multisystem disorder with variable manifestations and duration. One in 10 people with a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection will develop some manifestation of long COVID-19. Currently, there is no one single etiologic factor for the symptoms and signs of long COVID-19 beyond exposure to the SARS-CoV-2 virus. There are multiple theories about the pathophysiology ranging from viral persistence, reactivation, autoimmunity, and immune depletion. Certain risk factors have been identified including female sex, severe acute/hospitalized COVID-19, previous infections with SARS-CoV-2, and absence of vaccinations.</p>","PeriodicalId":13562,"journal":{"name":"Infectious disease clinics of North America","volume":" ","pages":""},"PeriodicalIF":6.1,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143604766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Impact of Coronavirus Disease 2019 (COVID-19) on Vulnerable Communities: What the Clinician Should Know.
IF 6.1 3区 医学
Infectious disease clinics of North America Pub Date : 2025-03-10 DOI: 10.1016/j.idc.2025.02.006
Jodian A Pinkney
{"title":"The Impact of Coronavirus Disease 2019 (COVID-19) on Vulnerable Communities: What the Clinician Should Know.","authors":"Jodian A Pinkney","doi":"10.1016/j.idc.2025.02.006","DOIUrl":"https://doi.org/10.1016/j.idc.2025.02.006","url":null,"abstract":"<p><p>The COVID-19 pandemic unmasked striking health disparities within the US healthcare system and significantly impacted vulnerable populations. While much attention on vulnerability has been directed toward older individuals with underlying medical conditions, key populations-including the uninsured, racial and ethnic minorities, and pregnant individuals-were considerably affected and require intervention. This review examines the barriers these populations encountered and outlines how clinicians can engage at the provider, practice, community, and national levels to advance health equity and improve health outcomes for these groups in the post-pandemic era.</p>","PeriodicalId":13562,"journal":{"name":"Infectious disease clinics of North America","volume":" ","pages":""},"PeriodicalIF":6.1,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143604769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Navigating Coronavirus Disease 2019 in Immunocompromised Populations: Evolving Risk Factors, Treatment, and Outcomes.
IF 6.1 3区 医学
Infectious disease clinics of North America Pub Date : 2025-03-06 DOI: 10.1016/j.idc.2025.02.005
Majd Alsoubani, Jennifer Chow
{"title":"Navigating Coronavirus Disease 2019 in Immunocompromised Populations: Evolving Risk Factors, Treatment, and Outcomes.","authors":"Majd Alsoubani, Jennifer Chow","doi":"10.1016/j.idc.2025.02.005","DOIUrl":"https://doi.org/10.1016/j.idc.2025.02.005","url":null,"abstract":"<p><p>The coronavirus disease 2019 (COVID-19) pandemic has disproportionately impacted immunocompromised hosts, leading to higher morbidity and mortality. The clinical outcomes have varied based on the degree of immunosuppression, treatment availability, severe acute respiratory syndrome coronavirus 2 variants, and vaccination status. This review discusses the evolving epidemiology, clinical presentation, treatment, and prevention strategies for COVID-19 in immunocompromised populations, including patients living with human immunodeficiency virus, solid organ transplant, and hematopoietic stem cell transplant recipients.</p>","PeriodicalId":13562,"journal":{"name":"Infectious disease clinics of North America","volume":" ","pages":""},"PeriodicalIF":6.1,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143585288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Contributors
IF 6.1 3区 医学
Infectious disease clinics of North America Pub Date : 2025-01-30 DOI: 10.1016/S0891-5520(24)00092-8
{"title":"Contributors","authors":"","doi":"10.1016/S0891-5520(24)00092-8","DOIUrl":"10.1016/S0891-5520(24)00092-8","url":null,"abstract":"","PeriodicalId":13562,"journal":{"name":"Infectious disease clinics of North America","volume":"39 1","pages":"Pages iii-vi"},"PeriodicalIF":6.1,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143342204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Updates in Fungal Infections
IF 6.1 3区 医学
Infectious disease clinics of North America Pub Date : 2025-01-30 DOI: 10.1016/S0891-5520(24)00090-4
Alfred Luk (Editor), Luis Ostrosky-Zeichner (Editors)
{"title":"Updates in Fungal Infections","authors":"Alfred Luk (Editor),&nbsp;Luis Ostrosky-Zeichner (Editors)","doi":"10.1016/S0891-5520(24)00090-4","DOIUrl":"10.1016/S0891-5520(24)00090-4","url":null,"abstract":"","PeriodicalId":13562,"journal":{"name":"Infectious disease clinics of North America","volume":"39 1","pages":"Page i"},"PeriodicalIF":6.1,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143342208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Copyright
IF 6.1 3区 医学
Infectious disease clinics of North America Pub Date : 2025-01-30 DOI: 10.1016/S0891-5520(24)00091-6
{"title":"Copyright","authors":"","doi":"10.1016/S0891-5520(24)00091-6","DOIUrl":"10.1016/S0891-5520(24)00091-6","url":null,"abstract":"","PeriodicalId":13562,"journal":{"name":"Infectious disease clinics of North America","volume":"39 1","pages":"Page ii"},"PeriodicalIF":6.1,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143342207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Forthcoming Issues
IF 6.1 3区 医学
Infectious disease clinics of North America Pub Date : 2025-01-30 DOI: 10.1016/S0891-5520(24)00094-1
{"title":"Forthcoming Issues","authors":"","doi":"10.1016/S0891-5520(24)00094-1","DOIUrl":"10.1016/S0891-5520(24)00094-1","url":null,"abstract":"","PeriodicalId":13562,"journal":{"name":"Infectious disease clinics of North America","volume":"39 1","pages":"Page xi"},"PeriodicalIF":6.1,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143342206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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