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Prevention and Control of Clostridioides difficile Infection for the Infectious Diseases Clinician. 传染病临床医师对艰难梭菌感染的预防与控制。
IF 4.1 3区 医学
Infectious disease clinics of North America Pub Date : 2026-05-05 DOI: 10.1016/j.idc.2026.02.009
Lea Monday, Amar Krishna, Teena Chopra
{"title":"Prevention and Control of Clostridioides difficile Infection for the Infectious Diseases Clinician.","authors":"Lea Monday, Amar Krishna, Teena Chopra","doi":"10.1016/j.idc.2026.02.009","DOIUrl":"https://doi.org/10.1016/j.idc.2026.02.009","url":null,"abstract":"<p><p>This article highlights the challenges of preventing Clostridioides difficile infection (CDI) in health care settings. It emphasizes a multifaceted approach including hand hygiene, contact precautions, environmental cleaning, and antimicrobial stewardship. Diagnostic stewardship, using combined testing algorithms and electronic alerts, helps reduce unnecessary testing and misdiagnosis. Emerging strategies like microbiome restoration, vaccines, and monoclonal antibodies are under active investigation. When CDI rates remain high despite standard measures, additional interventions such as sporicidal disinfectants and no-touch technologies may be necessary. Overall, a comprehensive, adaptive approach is essential to effectively reduce CDI incidence and improve patient outcomes.</p>","PeriodicalId":13562,"journal":{"name":"Infectious disease clinics of North America","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147837499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Infection Control Strategies to Prevent Emergence and Transmission of Resistant Gram-Negative Bacteria. 预防耐药革兰氏阴性菌出现和传播的感染控制策略。
IF 4.1 3区 医学
Infectious disease clinics of North America Pub Date : 2026-04-28 DOI: 10.1016/j.idc.2026.02.007
John P Mills, Evgeny Rogozin, Hyeri Seok, Dror Marchaim
{"title":"Infection Control Strategies to Prevent Emergence and Transmission of Resistant Gram-Negative Bacteria.","authors":"John P Mills, Evgeny Rogozin, Hyeri Seok, Dror Marchaim","doi":"10.1016/j.idc.2026.02.007","DOIUrl":"https://doi.org/10.1016/j.idc.2026.02.007","url":null,"abstract":"<p><p>Multidrug-resistant gram-negative bacteria pose a major threat to patient safety, driven by efficient transmission within health care settings and increasing antimicrobial resistance. This review synthesizes current epidemiology, key reservoirs, and evidence-based prevention strategies for extended-spectrum β-lactamase-producing Enterobacterales, carbapenem-resistant Enterobacterales, carbapenem-resistant Pseudomonas aeruginosa , and carbapenem-resistant Acinetobacter baumannii. Core interventions include hand hygiene, targeted contact precautions, optimized environmental cleaning, and antimicrobial stewardship. Active surveillance and patient cohorting have selective roles depending on the specific organism, setting, and endemicity. Emerging tools, such as whole-genome sequencing, better delineate transmission dynamics to guide outbreak response.</p>","PeriodicalId":13562,"journal":{"name":"Infectious disease clinics of North America","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147770286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Preventing the Spread of Tuberculosis in Health Care Settings. 在卫生保健机构中预防结核病的传播。
IF 4.1 3区 医学
Infectious disease clinics of North America Pub Date : 2026-04-28 DOI: 10.1016/j.idc.2026.03.001
Mark I Grijalva, Jerry M Zuckerman
{"title":"Preventing the Spread of Tuberculosis in Health Care Settings.","authors":"Mark I Grijalva, Jerry M Zuckerman","doi":"10.1016/j.idc.2026.03.001","DOIUrl":"https://doi.org/10.1016/j.idc.2026.03.001","url":null,"abstract":"<p><p>This article outlines key strategies for preventing tuberculosis (TB) transmission in health care settings. It emphasizes a layered approach, including administrative controls like early detection and patient isolation, environmental measures such as proper ventilation and negative pressure rooms, and personal protective equipment like N95 respirators. Proper staff training, regular maintenance, and adherence to guidelines are crucial for effective infection control. The article highlights the importance of a comprehensive TB control plan to protect patients and health care personnel, reduce nosocomial infections, and ensure safety through early diagnosis, environmental management, and proper use of respiratory protection.</p>","PeriodicalId":13562,"journal":{"name":"Infectious disease clinics of North America","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147770261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Threats to Success: Principles of Infection Prevention and Control in Health Care Settings, Part 2: Device and Pathogen Management. 成功的威胁：卫生保健机构感染预防和控制原则，第2部分：设备和病原体管理。
IF 4.1 3区 医学
Infectious disease clinics of North America Pub Date : 2026-04-10 DOI: 10.1016/j.idc.2026.03.002
Keith S Kaye, Sorabh Dhar
{"title":"Threats to Success: Principles of Infection Prevention and Control in Health Care Settings, Part 2: Device and Pathogen Management.","authors":"Keith S Kaye, Sorabh Dhar","doi":"10.1016/j.idc.2026.03.002","DOIUrl":"https://doi.org/10.1016/j.idc.2026.03.002","url":null,"abstract":"","PeriodicalId":13562,"journal":{"name":"Infectious disease clinics of North America","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147672932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ventilator-Associated Events: Surveillance and Prevention. 呼吸机相关事件：监测和预防。
IF 4.1 3区 医学
Infectious disease clinics of North America Pub Date : 2026-04-09 DOI: 10.1016/j.idc.2026.02.005
Marie-Céline Zanella, Chanu Rhee, Michael Klompas
{"title":"Ventilator-Associated Events: Surveillance and Prevention.","authors":"Marie-Céline Zanella, Chanu Rhee, Michael Klompas","doi":"10.1016/j.idc.2026.02.005","DOIUrl":"https://doi.org/10.1016/j.idc.2026.02.005","url":null,"abstract":"<p><p>The ventilator-associated event (VAE) framework provides objective, reproducible surveillance for a broad range of infectious and noninfectious complications of mechanical ventilation. VAEs are associated with prolonged mechanical ventilation, extended ICU stays, and increased mortality independent of patients' underlying conditions, making them valuable quality indicators for risk identification and benchmarking. VAE rates can be reduced by minimizing sedation, conducting daily awakening and breathing trials, optimizing fluid management, using real-time alerts for impending VAEs, and integrating these measures into ventilator care bundles. VAE surveillance provides objective insight into the safety of mechanical ventilation and can help identify opportunities to improve patient outcomes.</p>","PeriodicalId":13562,"journal":{"name":"Infectious disease clinics of North America","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147654002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nosocomial Fungal Infections: Epidemiology, Control Strategies, and Prevention of Candida and Other Yeasts. 医院真菌感染：流行病学、控制策略和预防念珠菌和其他酵母菌。
IF 4.1 3区 医学
Infectious disease clinics of North America Pub Date : 2026-04-01 DOI: 10.1016/j.idc.2026.02.008
Geehan Suleyman, George J Alangaden
{"title":"Nosocomial Fungal Infections: Epidemiology, Control Strategies, and Prevention of Candida and Other Yeasts.","authors":"Geehan Suleyman, George J Alangaden","doi":"10.1016/j.idc.2026.02.008","DOIUrl":"https://doi.org/10.1016/j.idc.2026.02.008","url":null,"abstract":"<p><p>Invasive candidiasis is a leading cause of hospital-acquired infections, often linked to invasive devices, immunosuppression, and environmental contamination. Conventional culture-based diagnostics lack sensitivity, making advanced nonculture-based methods essential for accurate detection. Prevention requires stringent infection control practices and antifungal prophylaxis in high-risk patients. Candida auris, an emerging multidrug-resistant pathogen, poses significant challenges due to its potential for nosocomial outbreaks. Active surveillance and rigorous infection prevention measures are critical for early detection and containment of transmission in health care settings.</p>","PeriodicalId":13562,"journal":{"name":"Infectious disease clinics of North America","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147608715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Role of Infection Prevention in Preventing the Spread of Vancomycin-Resistant Enterococci in Health Care Settings. 感染预防在预防万古霉素耐药肠球菌在卫生保健机构传播中的作用
IF 4.1 3区 医学
Infectious disease clinics of North America Pub Date : 2026-03-31 DOI: 10.1016/j.idc.2026.02.006
Anita Shallal, Kyle Crooker, Marcus Zervos, Gina Maki
{"title":"The Role of Infection Prevention in Preventing the Spread of Vancomycin-Resistant Enterococci in Health Care Settings.","authors":"Anita Shallal, Kyle Crooker, Marcus Zervos, Gina Maki","doi":"10.1016/j.idc.2026.02.006","DOIUrl":"https://doi.org/10.1016/j.idc.2026.02.006","url":null,"abstract":"<p><p>We describe the role of infection prevention in Vancomycin-Resistant Enterococci (VRE) in the health care setting. Despite low levels of virulence, VRE is a global challenge due to an increasing trend in resistance, including novel agents. Basic infection control practices to interrupt transmission, such as hand hygiene, environmental cleaning, and antimicrobial stewardship, are crucial in preventing the spread of VRE. Reducing patient-specific risk factors, such as the presence of indwelling devices, is also crucial. The use of active surveillance screening and contact precautions is not shown to reduce VRE transmission in endemic settings.</p>","PeriodicalId":13562,"journal":{"name":"Infectious disease clinics of North America","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147591963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Roles and Processes for Pandemic Preparedness in Infection Control. 感染控制中大流行防备的作用和过程。
IF 4.1 3区 医学
Infectious disease clinics of North America Pub Date : 2026-03-26 DOI: 10.1016/j.idc.2026.01.013
Jessica I Abrantes-Figueiredo, David B Banach
{"title":"Roles and Processes for Pandemic Preparedness in Infection Control.","authors":"Jessica I Abrantes-Figueiredo, David B Banach","doi":"10.1016/j.idc.2026.01.013","DOIUrl":"https://doi.org/10.1016/j.idc.2026.01.013","url":null,"abstract":"<p><p>Being adequately prepared for future pandemics is an absolute necessity for healthcare facilities so that quality patient care may continue while also protecting healthcare personnel. Strategies to protect healthcare personnel and mitigate staffing shortages must be priority to maintain inpatient, ambulatory, and preventative services. Infection preventionists and healthcare epidemiologists are experts within their respective fields and key staff that should be involved in emergency management planning alongside facility leadership. Effective communication may help bridge the gap between the unknowns of a pandemic and prevention of burnout among healthcare workers challenged with facing ethical dilemmas.</p>","PeriodicalId":13562,"journal":{"name":"Infectious disease clinics of North America","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147528321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Role of Infection Prevention in Monitoring and Preventing Healthcare-Associated Viral Respiratory Infection. 感染预防在监测和预防卫生保健相关的病毒性呼吸道感染中的作用。
IF 4.1 3区 医学
Infectious disease clinics of North America Pub Date : 2026-03-26 DOI: 10.1016/j.idc.2026.01.012
Mary Morgan Lee, Thomas R Talbot
{"title":"The Role of Infection Prevention in Monitoring and Preventing Healthcare-Associated Viral Respiratory Infection.","authors":"Mary Morgan Lee, Thomas R Talbot","doi":"10.1016/j.idc.2026.01.012","DOIUrl":"https://doi.org/10.1016/j.idc.2026.01.012","url":null,"abstract":"<p><p>Health care-associated viral respiratory infections are common and cause increased patient morbidity and mortality. Although the threat of viral respiratory infection was underscored by the COVID-19 pandemic, respiratory viruses continue to have a significant impact in health care settings. Studies report decreased nosocomial transmission when aggressive infection control measures are implemented with more success using a multicomponent approach. This review focuses on the epidemiology, transmission, and role of infection prevention in the control of health care-associated respiratory viral infections.</p>","PeriodicalId":13562,"journal":{"name":"Infectious disease clinics of North America","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147528363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Beyond Methicillin-resistant Staphylococcus aureus: Prevention Strategies for Health Care-Associated Staphylococcus aureus Infection. 超越耐甲氧西林金黄色葡萄球菌：卫生保健相关金黄色葡萄球菌感染的预防策略。
IF 4.1 3区 医学
Infectious disease clinics of North America Pub Date : 2026-03-26 DOI: 10.1016/j.idc.2026.01.011
Davide Bosetti, Andie Lee, Gaud Catho, Stephan Harbarth
{"title":"Beyond Methicillin-resistant Staphylococcus aureus: Prevention Strategies for Health Care-Associated Staphylococcus aureus Infection.","authors":"Davide Bosetti, Andie Lee, Gaud Catho, Stephan Harbarth","doi":"10.1016/j.idc.2026.01.011","DOIUrl":"https://doi.org/10.1016/j.idc.2026.01.011","url":null,"abstract":"<p><p>Staphylococcus aureus remains a leading cause of health care-associated infection. Although methicillin-resistant S aureus (MRSA) has declined in many high-income settings, methicillin-susceptible S aureus (MSSA) continues to cause many invasive infections. Thus, infection control programs only focused on MRSA have now become obsolete. Considering also that MRSA spread is mainly exogenous and MSSA infection often arises from endogenous carriage, this article attempts to synthesize evidence for horizontal (non-pathogen-specific) strategies-hand and environmental hygiene, device care, universal decolonization in high-risk units, optimized surgical prophylaxis-and vertical (targeted) measures such as targeted MRSA/MSSA screening and decolonization.</p>","PeriodicalId":13562,"journal":{"name":"Infectious disease clinics of North America","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147528129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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