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Jaw Osteomyelitis. 下巴骨髓炎。
IF 6.1 3区 医学
Infectious disease clinics of North America Pub Date : 2025-05-25 DOI: 10.1016/j.idc.2025.02.015
Carlos Alejandro Portales Castillo, Mohammad Mousavian, Zachary Peacock, Miriam Baron Barshak
{"title":"Jaw Osteomyelitis.","authors":"Carlos Alejandro Portales Castillo, Mohammad Mousavian, Zachary Peacock, Miriam Baron Barshak","doi":"10.1016/j.idc.2025.02.015","DOIUrl":"https://doi.org/10.1016/j.idc.2025.02.015","url":null,"abstract":"<p><p>Mandibular osteomyelitis is caused most commonly by members of the oral flora in the setting of dental infection or dental manipulation, often in patients with underlying mandible pathology. Recognizing and treating mandible infections is especially challenging when they are associated with osteonecrotic conditions that are themselves difficult to manage and that may be associated with symptoms and testing results that mimic infection. Optimized diagnosis and management of mandible infections require collaboration between specialists in surgical and medical aspects of care, with the goal of clearing or controlling infection while maximizing function.</p>","PeriodicalId":13562,"journal":{"name":"Infectious disease clinics of North America","volume":" ","pages":""},"PeriodicalIF":6.1,"publicationDate":"2025-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144150381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Periprosthetic Joint Infections. 假体周围关节感染。
IF 6.1 3区 医学
Infectious disease clinics of North America Pub Date : 2025-05-23 DOI: 10.1016/j.idc.2025.02.010
Angela L Hewlett, Beau J Kildow, Nicolás W Cortés-Penfield
{"title":"Periprosthetic Joint Infections.","authors":"Angela L Hewlett, Beau J Kildow, Nicolás W Cortés-Penfield","doi":"10.1016/j.idc.2025.02.010","DOIUrl":"https://doi.org/10.1016/j.idc.2025.02.010","url":null,"abstract":"<p><p>Periprosthetic joint infection (PJI) is a dreaded and devastating complication of total joint arthroplasty. The clinical presentation of PJI is dependent on multiple factors, but typically involves pain, swelling, warmth and erythema of the affected joint. The management of PJI is complex, with both the medical and surgical approach being scenario specific. The importance of interdisciplinary collaboration to manage these complicated infections cannot be overstated. This review, aimed at the practicing infectious diseases clinician, details the background, microbiology, clinical presentation, diagnosis and both surgical and medical treatment of PJI.</p>","PeriodicalId":13562,"journal":{"name":"Infectious disease clinics of North America","volume":" ","pages":""},"PeriodicalIF":6.1,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144142408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Local Antibiotic Delivery in Orthopedics: Review of Current Practices and Emerging Technologies. 骨科局部抗生素递送：当前实践和新兴技术的回顾。
IF 6.1 3区 医学
Infectious disease clinics of North America Pub Date : 2025-05-22 DOI: 10.1016/j.idc.2025.03.002
Jenny R Aronson, Julie Ann Justo, Derek F Amanatullah
{"title":"Local Antibiotic Delivery in Orthopedics: Review of Current Practices and Emerging Technologies.","authors":"Jenny R Aronson, Julie Ann Justo, Derek F Amanatullah","doi":"10.1016/j.idc.2025.03.002","DOIUrl":"https://doi.org/10.1016/j.idc.2025.03.002","url":null,"abstract":"<p><p>This article explores the role of local antibiotic delivery in the management of orthopedic infections, a significant challenge in modern healthcare. This article delineates between prophylactic and therapeutic uses of antibiotics, examining various delivery methods, including topical powders, irrigation solutions, intraosseous injections, and antibiotic-loaded bone cement. While local administration aims to enhance therapeutic efficacy and minimize systemic exposure, there is limited evidence supporting effectiveness. The article aims to review the current practices and evidence and highlight emerging strategies such as hydrogels and biodegradable systems. Ongoing research is essential to optimize these methods and improve patient outcomes in orthopedic care.</p>","PeriodicalId":13562,"journal":{"name":"Infectious disease clinics of North America","volume":" ","pages":""},"PeriodicalIF":6.1,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144132308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Copyright 版权
IF 6.1 3区 医学
Infectious disease clinics of North America Pub Date : 2025-05-06 DOI: 10.1016/S0891-5520(25)00030-3
{"title":"Copyright","authors":"","doi":"10.1016/S0891-5520(25)00030-3","DOIUrl":"10.1016/S0891-5520(25)00030-3","url":null,"abstract":"","PeriodicalId":13562,"journal":{"name":"Infectious disease clinics of North America","volume":"39 2","pages":"Page ii"},"PeriodicalIF":6.1,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143911824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Updates on COVID-19 COVID-19最新情况
IF 6.1 3区 医学
Infectious disease clinics of North America Pub Date : 2025-05-06 DOI: 10.1016/S0891-5520(25)00029-7
Rajesh T. Gandhi (Editor), Michael R. Jordan (Editors)
{"title":"Updates on COVID-19","authors":"Rajesh T. Gandhi (Editor),&nbsp;Michael R. Jordan (Editors)","doi":"10.1016/S0891-5520(25)00029-7","DOIUrl":"10.1016/S0891-5520(25)00029-7","url":null,"abstract":"","PeriodicalId":13562,"journal":{"name":"Infectious disease clinics of North America","volume":"39 2","pages":"Page i"},"PeriodicalIF":6.1,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143911823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Contributors 贡献者
IF 6.1 3区 医学
Infectious disease clinics of North America Pub Date : 2025-05-06 DOI: 10.1016/S0891-5520(25)00031-5
{"title":"Contributors","authors":"","doi":"10.1016/S0891-5520(25)00031-5","DOIUrl":"10.1016/S0891-5520(25)00031-5","url":null,"abstract":"","PeriodicalId":13562,"journal":{"name":"Infectious disease clinics of North America","volume":"39 2","pages":"Pages iii-iv"},"PeriodicalIF":6.1,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143911942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Forthcoming Issues 即将到来的问题
IF 6.1 3区 医学
Infectious disease clinics of North America Pub Date : 2025-05-06 DOI: 10.1016/S0891-5520(25)00033-9
{"title":"Forthcoming Issues","authors":"","doi":"10.1016/S0891-5520(25)00033-9","DOIUrl":"10.1016/S0891-5520(25)00033-9","url":null,"abstract":"","PeriodicalId":13562,"journal":{"name":"Infectious disease clinics of North America","volume":"39 2","pages":"Page viii"},"PeriodicalIF":6.1,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143911551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Optimizing Antibiotic Therapy in Musculoskeletal Infections. 优化肌肉骨骼感染的抗生素治疗。
IF 6.1 3区 医学
Infectious disease clinics of North America Pub Date : 2025-04-11 DOI: 10.1016/j.idc.2025.02.009
Nicolás W Cortés-Penfield, Julie Ann Justo, Erin K McCreary, Jonathan H Ryder
{"title":"Optimizing Antibiotic Therapy in Musculoskeletal Infections.","authors":"Nicolás W Cortés-Penfield, Julie Ann Justo, Erin K McCreary, Jonathan H Ryder","doi":"10.1016/j.idc.2025.02.009","DOIUrl":"https://doi.org/10.1016/j.idc.2025.02.009","url":null,"abstract":"<p><p>Research into the optimal antibiotic management of musculoskeletal infections has advanced tremendously over the past quarter century, including over a dozen randomized controlled trials and numerous observational studies. This review examines the rationale for and evidence base supporting modern approaches to antibiotic decision making and stewardship in orthopedic infections. Specific practice advances discussed include the increased and earlier use of oral antibiotics, other principles of antibiotic selection (eg, the notion of \"bone penetration\" and novel local antimicrobial strategies), individualizing durations of therapy, and increasingly selective approaches to empiric antipseudomonal therapy, suppressive antibiotic therapy, and periprocedural antimicrobial prophylaxis following arthroplasty.</p>","PeriodicalId":13562,"journal":{"name":"Infectious disease clinics of North America","volume":" ","pages":""},"PeriodicalIF":6.1,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143994816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pyogenic Vertebral Osteomyelitis. 化脓性椎体骨髓炎。
IF 6.1 3区 医学
Infectious disease clinics of North America Pub Date : 2025-04-08 DOI: 10.1016/j.idc.2025.02.011
Michael W Henry, James E Dowdell, Andy O Miller
{"title":"Pyogenic Vertebral Osteomyelitis.","authors":"Michael W Henry, James E Dowdell, Andy O Miller","doi":"10.1016/j.idc.2025.02.011","DOIUrl":"https://doi.org/10.1016/j.idc.2025.02.011","url":null,"abstract":"<p><p>Vertebral osteomyelitis is a general term for a heterogenous group of spine infections involving the vertebral bone, intervertebral discs, and facet joints. These infections can often spread contiguously to adjacent paraspinal structures, including paravertebral muscles and the epidural space and frequently presents with nonspecific and indolent symptoms, which can delay diagnosis. Treatment can be arduous, requiring prolonged courses of antibiotics often combined with surgical debridement. This review focuses primarily on pyogenic vertebral osteomyelitis in adults, reviewing the pathophysiology, epidemiology, microbiology, diagnosis, and treatment of this infection.</p>","PeriodicalId":13562,"journal":{"name":"Infectious disease clinics of North America","volume":" ","pages":""},"PeriodicalIF":6.1,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143998871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diabetic Foot Infections. 糖尿病足感染。
IF 6.1 3区 医学
Infectious disease clinics of North America Pub Date : 2025-04-08 DOI: 10.1016/j.idc.2025.02.014
Laila M Castellino, Peter A Crisologo, Avneesh Chhabra, Orhan K Öz
{"title":"Diabetic Foot Infections.","authors":"Laila M Castellino, Peter A Crisologo, Avneesh Chhabra, Orhan K Öz","doi":"10.1016/j.idc.2025.02.014","DOIUrl":"https://doi.org/10.1016/j.idc.2025.02.014","url":null,"abstract":"<p><p>Diabetes is a growing public health concern, with diabetic foot infections (DFI) being one of the leading causes of lower extremity limb amputation in the United States. Accurate diagnosis of DFI requires a combination of clinical, laboratory, and radiologic tests to determine the extent and depth of infection, including the presence of osteomyelitis. Treatment often includes a combination of antibiotics and surgical debridement. Addressing comorbidities such as peripheral vascular disease, glycemic control, and offloading pressure from ulcers and bony prominences is paramount to achieving a successful outcome, and patients should ideally be managed by dedicated interdisciplinary teams.</p>","PeriodicalId":13562,"journal":{"name":"Infectious disease clinics of North America","volume":" ","pages":""},"PeriodicalIF":6.1,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144012916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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