艰难梭菌感染预防方法。

IF 4.1 3区医学 Q1 IMMUNOLOGY

Infectious disease clinics of North America Pub Date : 2025-08-08 DOI:10.1016/j.idc.2025.07.004

Jesse Vance, Nicholas A Turner

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引用次数: 0

摘要

难辨梭状芽胞杆菌的预防是具有挑战性的，因为孢子具有高度的弹性和传播源的多样性。手部卫生、接触预防和环境净化是预防感染的基本策略。抗菌药物管理在降低个人和机构层面的艰难梭菌风险方面非常有效。补充控制措施，如无接触消毒技术和筛查/隔离携带者，通常用于基本控制措施证明不足的情况。通过免疫、针对艰难梭菌的预防性抗生素或保护/增强微生物群的产品来减少宿主的脆弱性可能在未来提供希望。

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Infection Prevention Approaches for Clostridioides difficile.

Clostridioides difficile prevention is challenging as spores are highly resilient and transmission sources diverse. Hand hygiene, contact precautions, and environmental decontamination are fundamental infection prevention strategies. Antimicrobial stewardship is highly effective at reducing C difficile risk at both the individual and institutional level. Supplemental control measures such as no-touch disinfection technologies and screening/isolation of carriers are generally reserved for situations in which fundamental control measures prove insufficient. Reducing host vulnerability through immunization, prophylactic antibiotics directed against C difficile, or products that protect/augment the microbiome may offer promise in the future.

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来源期刊

Infectious disease clinics of North America 医学-传染病学

CiteScore

8.30

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Infectious Disease Clinics of North America updates you on the latest trends in the clinical diagnosis and management of patients with infectious diseases, keeps you up to date on the newest advances, and provides a sound basis for choosing treatment options. Each issue focuses on a single topic in infectious disease, including clinical microbiology, compromised host infections, gastrointestinal infections, global health, hepatitis, HIV/AIDS, hospital-acquired infections, travel medicine, infection control, bacterial infections, sexually transmitted diseases, urinary tract infections, and viral infections.