Industrial Psychiatry Journal最新文献

{"title":"A comparative study evaluating the efficacy of naltrexone versus acamprosate as anticraving agents in alcohol use disorder.","authors":"Samant Singh, Lakhan Kataria, Mohd Rashid Alam","doi":"10.4103/ipj.ipj_413_24","DOIUrl":"https://doi.org/10.4103/ipj.ipj_413_24","url":null,"abstract":"<p><strong>Background: </strong>Alcohol use disorders (AUDs) are characterized by excessive alcohol consumption, negatively impacting health, social life, and economic status. Globally, AUD contributes to significant disease burden, causing millions deaths annually. Despite the availability of treatments, relapse rates remain high. Naltrexone and acamprosate, two FDA-approved anticraving agents, are widely used to prevent relapse. However, comparative studies in Indian populations are limited, prompting this study to assess the efficacy of these drugs in treating AUD.</p><p><strong>Aim: </strong>This study aimed to compare the effectiveness of naltrexone and acamprosate as anticraving agents in treating AUD, evaluating the time to first drink (lapse) and time to relapse among patients using either medication at 1 and 3 months. It also assessed the correlation between baseline severity of AUD and the efficacy of naltrexone and acamprosate as anticraving agents, as well as compared demographic and clinical variables between the two treatment groups.</p><p><strong>Materials and methods: </strong>A prospective observational study was conducted on 70 patients diagnosed with AUD, divided into two groups: naltrexone (n = 35) and acamprosate (n = 35). Patients were assessed using the Obsessive Compulsive Drinking Scale (OCDS) and followed for 3 months to evaluate craving intensity, time to first drink, and relapse rates. The Quality of Life Scale (QOLS) and Clinical Global Impression (CGI) were used to assess treatment impact.</p><p><strong>Results: </strong>Both groups were comparable at baseline. At 3 months, naltrexone patients had higher abstinence rates (63.64%) compared with acamprosate (34.68%, <i>P</i> = 0.018). Naltrexone also significantly extended the time to first drink and relapse compared to acamprosate.</p><p><strong>Conclusion: </strong>Naltrexone demonstrated superior efficacy in maintaining abstinence and reducing relapse rates in AUD patients compared to acamprosate. These findings suggest that naltrexone may be more effective for long-term treatment in the Indian context.</p>","PeriodicalId":13534,"journal":{"name":"Industrial Psychiatry Journal","volume":"34 1","pages":"97-102"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12077622/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144078044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Alcohol dependent and GTCS patient with sleep-related hyper motor epilepsy.","authors":"Sriparno Patra, Soumitra Ghosh, Rupa Gohain","doi":"10.4103/ipj.ipj_183_24","DOIUrl":"https://doi.org/10.4103/ipj.ipj_183_24","url":null,"abstract":"","PeriodicalId":13534,"journal":{"name":"Industrial Psychiatry Journal","volume":"34 1","pages":"133-135"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12077642/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144078048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of neutrophil-to-lymphocyte ratio with antipsychotic administration in schizophrenia: A longitudinal study.","authors":"Rajnish Raj, Shabir Ahmad Dar, Zaid Ahmad Wani, Vaibhav Kumar Khare, Inaamul Haq","doi":"10.4103/ipj.ipj_6_25","DOIUrl":"https://doi.org/10.4103/ipj.ipj_6_25","url":null,"abstract":"<p><strong>Background: </strong>Studies have hypothesized the role of the immune-inflammatory process behind the pathophysiology of psychiatric disorders like schizophrenia. Antipsychotic medication has been shown to suppress inflammatory response via complex mechanisms alleviating psychiatric symptoms.</p><p><strong>Aim: </strong>To assess the relation of neutrophil-to-lymphocyte ratio (NLR) with antipsychotic administration and clinical symptomatology severity.</p><p><strong>Materials and methods: </strong>A longitudinal study was performed among 34 inpatients who fulfilled inclusion and exclusion criteria. Sociodemographic details were collected, and the brief psychiatric rating scale (BPRS) was applied during admission. Blood sampling was performed during baseline and at discharge for the NLR ratio (neutrophil count/lymphocyte count) with the application of BPRS.</p><p><strong>Results: </strong>The mean ± SD age of the population was 38.91 ± 11.44 years, with male gender predominance (N = 25, 73.5%). The median duration of illness and duration of treatment were 10 months and 40 days, respectively. Twelve (35.3%) subjects were antipsychotic naïve. The mean ± SD of BPRS and NLR during admission was 49.94 ± 5.33 and 2.49 ± 0.92 and during discharge was 26.76 ± 6.04 and 2.08 ± 0.72, respectively.</p><p><strong>Conclusion: </strong>The results confirmed the NLR-lowering effect of antipsychotics alongside lowering of clinical symptomatology. NLR has the potential to be a biomarker indicating antipsychotic treatment response.</p>","PeriodicalId":13534,"journal":{"name":"Industrial Psychiatry Journal","volume":"34 1","pages":"108-113"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12077625/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144078051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nonsyndromic craniosynostosis associated with bipolar affective disorder and mild cognitive disorder.","authors":"Priya Deepak, Mohit Agrawal, Prateek Yadav, Vinay S Chauhan","doi":"10.4103/ipj.ipj_48_24","DOIUrl":"https://doi.org/10.4103/ipj.ipj_48_24","url":null,"abstract":"","PeriodicalId":13534,"journal":{"name":"Industrial Psychiatry Journal","volume":"33 Suppl 1","pages":"S280-S281"},"PeriodicalIF":0.0,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11553583/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142619526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of internet addiction and its association with quality of sleep among secondary and higher secondary school students of Jamnagar Gujarat during COVID-19.","authors":"Niraj P Patel, Anusha S Garg, Deepak S Tiwari, Viral R Shah","doi":"10.4103/ipj.ipj_123_24","DOIUrl":"https://doi.org/10.4103/ipj.ipj_123_24","url":null,"abstract":"<p><strong>Background: </strong>The internet is a vital part of present-day society. Internet use for education has increased in recent years. During the COVID pandemic, schools were closed and education was delivered through online methods, which led to a further increase in internet use, especially in adolescents, leading to internet addiction in some.</p><p><strong>Aim: </strong>To estimate the prevalence of internet addiction and poor quality of sleep in adolescent students of Jamnagar.</p><p><strong>Materials and methods: </strong>This cross-sectional study was carried out between January 2022 to March 2022 and included 1778 adolescent students of Jamnagar, Gujarat. The internet addiction test was used to measure the level of internet addiction, and the short Pittsburgh sleep quality index was used to measure the quality of sleep. Data analysis was conducted using the Chi-square test, Mann-Whitney U test, and multiple logistic regression techniques.</p><p><strong>Results: </strong>In our study, 17.8% of participants had mild internet addiction, 3.2% of participants had moderate-to-severe internet addiction, and 79% of participants were average internet users. Associated variables with internet addiction were male gender, residence at home, duration of internet usage in years, daily hours spent online, and monthly expenditure on internet recharge. Furthermore, 27.2% of participants had poor quality of sleep. Female gender, secondary school education, residence at the hostel, and internet addiction were predictors of poor quality of sleep.</p><p><strong>Conclusion: </strong>Students were found to have a high prevalence of internet addiction. The internet usage increased amid the COVID-19 pandemic. Internet addiction was significantly associated with poor quality of sleep in adolescents.</p>","PeriodicalId":13534,"journal":{"name":"Industrial Psychiatry Journal","volume":"33 Suppl 1","pages":"S193-S200"},"PeriodicalIF":0.0,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11553626/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142619539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Translational research in psychiatry.","authors":"Vinay Singh Chauhan, Markanday Sharma","doi":"10.4103/ipj.ipj_67_24","DOIUrl":"https://doi.org/10.4103/ipj.ipj_67_24","url":null,"abstract":"<p><p>Translational research in psychiatry bridges the gap between basic scientific discoveries and clinical applications, aiming to improve the diagnosis, treatment, and prevention of mental illnesses. By elucidating the neurobiological mechanisms underlying psychiatric disorders through neuroimaging, genetics, and animal models, researchers can identify novel therapeutic targets and biomarkers for personalized interventions. This brief communication provides an overview of the importance, approaches, and a few examples of translation psychiatry research and challenges. Moving forward, collaboration between researchers, clinicians, industry partners, and regulatory agencies is essential to address the unmet needs of individuals affected by mental illness and to realize the full potential of translational psychiatry.</p>","PeriodicalId":13534,"journal":{"name":"Industrial Psychiatry Journal","volume":"33 Suppl 1","pages":"S233-S235"},"PeriodicalIF":0.0,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11553615/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142619556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations between cognitive disengagement syndrome, Internet addiction, and Internet gaming disorder among medical students - A cross-sectional study.","authors":"Yogesh Murugan, Dipen Thakkar, Rohitkumar Ram, Kadalarasu Dhanapal","doi":"10.4103/ipj.ipj_325_23","DOIUrl":"https://doi.org/10.4103/ipj.ipj_325_23","url":null,"abstract":"<p><strong>Background: </strong>Internet addiction (IA) and gaming disorder (IGD) are emerging public health concerns among youth. Sluggish cognitive tempo (SCT)/cognitive disengagement syndrome has been linked with risky online behaviors, but the literature on medical students is limited.</p><p><strong>Aim: </strong>To determine associations between SCT, IA, and IGD in Indian medical undergraduates.</p><p><strong>Materials and methods: </strong>The study included 303 medical students (ages: 18-24, 66% male). The Sociodemographic Information Form, Barkley SCT Scale, Young Internet Addiction Test-Short Form, and The Digital Game Addiction Scale were utilized to collect data. Contingency Table analyses, Mann-Whitey U-test, Chi-square test, and correlation analyses were used for analysis.</p><p><strong>Results: </strong>The prevalence of IA and IGD was 101 (33.3%) and 61 (20%), respectively. Students with IA or IGD had significantly higher SCT, daydreaming, and sluggishness scores (<i>P</i> < 0.01). SCT, daydreaming, and sluggishness showed significant positive correlations with IA and IGD severity (<i>P</i> < 0.01).</p><p><strong>Conclusion: </strong>Greater SCT symptoms demonstrated significant associations with increased risk of IA and IGD among medical students. Screening for SCT alongside IA and IGD may enable targeted interventions to promote healthy Internet use.</p>","PeriodicalId":13534,"journal":{"name":"Industrial Psychiatry Journal","volume":"33 Suppl 1","pages":"S210-S214"},"PeriodicalIF":0.0,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11553613/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142619402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychological autopsy study of suicides in farmers: Study from Kerala.","authors":"Pattath Narayanan Suresh Kumar, Rohith Suresh","doi":"10.4103/ipj.ipj_136_24","DOIUrl":"https://doi.org/10.4103/ipj.ipj_136_24","url":null,"abstract":"<p><strong>Background: </strong>Though agricultural farming is considered a peaceful and healthy industry it has a high rate of mortality especially suicide. In India, 11.2% of suicides are reported in the farming sector.</p><p><strong>Aim: </strong>To identify the role of psychosocial factors leading to farmer's suicide in a farmer's dominant district of Kerala.</p><p><strong>Material and method: </strong>One hundred and sixty-six successive suicides in Wayanad district and age, sex, marital status, and financial status matched normal controls residing in the same locality were evaluated and compared on psycho-social demographic variables, life events, and details of suicide.</p><p><strong>Results: </strong>Significantly a greater number of victims were living separately, living in rented homes, had no own land for cultivation, migrated, had marital discord, and strained relationships with relatives. They had loans from private financial enterprises and single money persons, had past attempts, a family history of alcoholism, and highly stressful life events. The most frequent psychiatric diagnosis was alcohol dependence/abuse followed by depression. The majority committed suicide by hanging followed by insecticide poisoning. Intention to commit suicide was expressed by 38.5% and 30.2% were intoxicated at the time of attempt. The venue for the attempt was the own house in 75.7% of cases.</p><p><strong>Conclusion: </strong>This study suggests the following remedial measures to prevent farmers' suicides. Expert advice to manage financial constraints like availing loans, crop insurance, etc. Guidance from the agricultural department for cost-effective cultivation. Early identification and treatment of psychiatric disorders.</p>","PeriodicalId":13534,"journal":{"name":"Industrial Psychiatry Journal","volume":"33 Suppl 1","pages":"S23-S28"},"PeriodicalIF":0.0,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11553611/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142619461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Geopolitical determinants of mental health and global health inequities.","authors":"Koravangattu Valsraj, Helena Ferreira Moura, Kanthee Anantapong, Antonio Ventriglio, Albert Persaud, Rachel Tribe, Max Pemberton, Dan Poulter, Dinesh Bhugra","doi":"10.4103/ipj.ipj_32_24","DOIUrl":"https://doi.org/10.4103/ipj.ipj_32_24","url":null,"abstract":"<p><p>Geopolitical determinants of health have been well recognized by the World Health Organization and are increasingly being discussed across governments, institutions, academics, policy makers, and across global health sector. Geopolitical determinants of health are events, structures, processes, and factors that influence individual health including mental health, public and population mental health both directly and indirectly. Consequently, nation's responses to these factors will affect short-term and long-term health outcomes. Geopolitical factors are becoming increasingly more important as they influence directly and indirectly social determinants of health. These factors clearly impact both physical and mental health leading to health inequities and inequalities. It is important to factor in geopolitical determinants in resource allocation and funding as well as policy making as has been highlighted by the recent pandemic and variable access to vaccines. Geopolitical determinants would be integral when addressing all global health inequities. These play a major role in resource allocation, policy and planning to meet today's global health challenges.</p>","PeriodicalId":13534,"journal":{"name":"Industrial Psychiatry Journal","volume":"33 Suppl 1","pages":"S250-S256"},"PeriodicalIF":0.0,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11553616/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142619454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transcranial direct current stimulation as an augmentation therapy in patients with obsessive-compulsive disorder: A case series.","authors":"Ipsita Basu, Srikrishna Prasad Panda, Prateek Yadav","doi":"10.4103/ipj.ipj_56_24","DOIUrl":"https://doi.org/10.4103/ipj.ipj_56_24","url":null,"abstract":"<p><p>Obsessive-compulsive disorder (OCD) is characterized by intrusive, distressing thoughts and/or repetitive behaviors. Transcranial direct current stimulation (tDCS) is a promising neuromodulation technique for augmenting pharmacotherapy in OCD. This case series identified patients diagnosed with OCD, who showed residual symptoms even after two adequate trials of pharmacotherapy corroborated using the Yale-Brown Obsessive Compulsive Scale (Y-BOCS) (score of eight and above taken as cutoff). tDCS was given in the form of two milliamperes current with anode at SMA and cathode at the right orbitofrontal area, for twenty minutes, for six sessions (one session per day) in addition to pharmacotherapy. Clinical assessment was performed using the Y BOCS at baseline and post treatment. The results revealed a reduction in OCD symptom severity in all the patients (as per both subjective report and Y-BOCS scores). The patients did not have any severe adverse effects. tDCS appears to be a potential augmentation therapy for individuals with OCD. However, further research is warranted to optimize stimulation parameters and elucidate the long-term effects of tDCS as part of a comprehensive treatment approach for OCD.</p>","PeriodicalId":13534,"journal":{"name":"Industrial Psychiatry Journal","volume":"33 Suppl 1","pages":"S226-S228"},"PeriodicalIF":0.0,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11553623/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142619554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}