Industrial Psychiatry Journal最新文献

{"title":"Digital twins in dementia: Early evidence and future directions for precision psychiatry.","authors":"Dharmendra Kumar Gupta, Arunima Chaudhuri","doi":"10.4103/ipj.ipj_309_25","DOIUrl":"10.4103/ipj.ipj_309_25","url":null,"abstract":"<p><p>Dementia remains a major global health challenge, with limited progress in early diagnosis and therapy. Emerging digital twin technologies-virtual computational replicas of patients or biological systems-offer new possibilities for precision medicine. This brief review summarizes current evidence on digital twin applications in dementia across diagnosis, care, drug discovery, and computational modelling. Twenty relevant studies published between 2015 and 2025 were identified, including empirical, conceptual, and <i>in-silico</i> works. The initial database search across PubMed, Scopus, Web of Science, and IEEE Xplore yielded 1,302 records, of which 20 met the inclusion criteria following PRISMA-based screening. Findings suggest that digital twins hold promise in drug discovery, where in-silico simulations accelerate compound screening and repurposing. Diagnostic models using EEG and neuroimaging twins demonstrate potential for early detection but lack clinical validation. Applications in care and rehabilitation remain conceptual, focusing on therapy planning and immersive cognitive interventions. Foundational computational studies lay theoretical groundwork for simulating neurodegenerative processes. Overall, digital twins represent an evolving frontier in dementia research, with significant opportunities, but limited clinical translation. Establishing longitudinal validation, integrating multimodal data, and adopting ethical frameworks will be critical for realizing their precision medicine potential. Ethical and governance discussions remain scarce, particularly around patient autonomy and data bias, underscoring the need for dementia-specific digital health ethics frameworks.</p>","PeriodicalId":13534,"journal":{"name":"Industrial Psychiatry Journal","volume":"35 2","pages":"226-229"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13561492/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148944694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The virtue of gratitude in mental health.","authors":"Danny Salka, Victor Ajluni","doi":"10.4103/ipj.ipj_376_25","DOIUrl":"10.4103/ipj.ipj_376_25","url":null,"abstract":"","PeriodicalId":13534,"journal":{"name":"Industrial Psychiatry Journal","volume":"35 2","pages":"230-231"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13561493/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148944842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Olanzapine induced hepatotoxicity in a young female with psychosis.","authors":"Prashant Wayal, Raja Babu Ramawat, Omar Afroz, Vaibhav Patil, Mamta Sood","doi":"10.4103/ipj.ipj_434_25","DOIUrl":"10.4103/ipj.ipj_434_25","url":null,"abstract":"","PeriodicalId":13534,"journal":{"name":"Industrial Psychiatry Journal","volume":"35 2","pages":"234-236"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13561495/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148929857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Complex auditory hallucinations associated with hearing impairment in elderly adults.","authors":"J V Ashwin, Mohit Kumar Shahi, Astha Singh, Bhupendra Singh, Sanjay Balasubramaniam","doi":"10.4103/ipj.ipj_191_25","DOIUrl":"10.4103/ipj.ipj_191_25","url":null,"abstract":"<p><p>Auditory hallucinations are a common yet underexplored phenomenon in individuals with hearing impairment, particularly in the elderly. Oliver Sacks syndrome, often seen in patients with sensory deprivation, is typically characterized by musical hallucinations but can also present with nonmusical auditory experiences. This case series presents three elderly patients with hearing impairment who experienced a range of auditory hallucinations, including voices, instrumental music, and environmental sounds, all localized to the ear with greater hearing loss. Despite these auditory experiences, patients demonstrated good insight and no signs of psychosis or cognitive decline. Comprehensive clinical evaluations ruled out other conditions, and diagnoses of Oliver Sacks syndrome were confirmed. The neurobiology underlying these hallucinations involves sensory deprivation leading to maladaptive cortical reorganization, with overactivity in dopaminergic pathways and dysfunction in the auditory cortex contributing to the hallucinations. All patients were treated with risperidone, melatonin, and hearing aids, leading to significant improvements in the frequency and intensity of hallucinations. This case series highlights the diverse nature of auditory hallucinations in elderly individuals with hearing impairment, stressing the importance of recognizing sensory deprivation as a contributing factor and utilizing a comprehensive approach to treatment.</p>","PeriodicalId":13534,"journal":{"name":"Industrial Psychiatry Journal","volume":"35 2","pages":"223-225"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13561465/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148929871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neuroacanthocytosis masquerading as psychiatric illness.","authors":"Ravi Sharma, Amita Thakur, Sumeesha Jaswal","doi":"10.4103/ipj.ipj_412_25","DOIUrl":"10.4103/ipj.ipj_412_25","url":null,"abstract":"","PeriodicalId":13534,"journal":{"name":"Industrial Psychiatry Journal","volume":"35 2","pages":"239-240"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13561480/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148944728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Self-compassion and obsessive-compulsive disorder: A systematic review.","authors":"Preeti Pandey, Mehfooz Ahmad, Shweta Jha","doi":"10.4103/ipj.ipj_24_25","DOIUrl":"10.4103/ipj.ipj_24_25","url":null,"abstract":"<p><p>The understanding of obsessive-compulsive disorder (OCD) has indeed evolved significantly over time, moving away from historical attributions like demonic possession to modern, evidence-based biological, and psychological explanations. Among psychological explanations, the emergence of third-wave cognitive behavioral therapies (CBT) has broadened the focus from traditional cognitive models to include factors related to the individual's relationship with their own experiences. One such factor gaining attention in OCD research is self-compassion. Self-compassion, rooted in mindfulness and self-kindness, contrasts with the self-criticism and harsh self-judgment often experienced by individuals with OCD. This systematic review provides an in-depth exploration of the relationship between self-compassion and OCD. Following preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines, PubMed, Scopus, and Google Scholar databases were systematically searched, and 13 studies were identified. While all studies identified a negative correlation between self-compassion and OCD severity, their conclusions about self-compassion's role in influencing OCD varied. Some studies found that self-compassion was not a predictor of OCD severity, others identified it as a predictor, and some suggested it influenced OCD through specific pathways. Overall, self-compassion appears to be a promising factor in understanding and treating OCD. Further research is needed to explore its role in greater depth.</p>","PeriodicalId":13534,"journal":{"name":"Industrial Psychiatry Journal","volume":"35 2","pages":"187-191"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13561488/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148944726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and pattern of anxiety in female health care workers in a tertiary care hospital.","authors":"Mansi A Tank, Malavika Thampuratti, Kalpesh V Chandrani, Avinash M Vyas","doi":"10.4103/ipj.ipj_278_25","DOIUrl":"10.4103/ipj.ipj_278_25","url":null,"abstract":"<p><strong>Background: </strong>Anxiety is very common in working females and particularly in those who are working in health care industry and it varies depending upon various sociodemographic factors.</p><p><strong>Aim: </strong>To asses prevalence and pattern of anxiety and its correlation with sociodemographic factors in female health care workers.</p><p><strong>Materials and methods: </strong>A cross sectional, observational study was conducted on 300 female workers in tertiary care hospital in India. Sociodemographic data were collected using a semi-structured proforma. DSM-5 based interview was conducted to diagnose anxiety spectrum disorder after that Hamilton anxiety scale was used to assess severity in all participants and it was correlated with sociodemographic factors. Statical analysis: Data were entered in excel sheet and analysed with Microsoft excel-2013 and SPSS. Chi square, Kruskal-Walli's test and Mann Whitney U tests were applied and <i>P</i> value < 0.05 was considered significant.</p><p><strong>Results: </strong>A study found that 25% of female healthcare workers experienced anxiety symptoms, with 17.3% reporting mild and 7.7% moderate anxiety. Sociodemographic and occupational factors associated with higher anxiety levels including age, education level, family size, socioeconomic status, having children, medical comorbidities, work experience, job type, and shift work patterns.</p><p><strong>Conclusion: </strong>Mild to moderate level of anxiety is common in female health workers and it correlates with several sociodemographic and occupational factors.</p>","PeriodicalId":13534,"journal":{"name":"Industrial Psychiatry Journal","volume":"35 2","pages":"208-212"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13561496/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148944681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"COVID-19-related psychological distress, fear, and reassurance-seeking behavior in the aftermath of the COVID-19 pandemic.","authors":"Bhushan Chaudhari, Tahoora Ali, Vidisha Nair, Parisha Kelkar, Suprakash Chaudhury, Ankit Janiani","doi":"10.4103/ipj.ipj_297_24","DOIUrl":"10.4103/ipj.ipj_297_24","url":null,"abstract":"<p><strong>Background: </strong>The COVID-19 pandemic presented an unprecedented and dystopian situation for the entire population and had imminent mental health corollaries specific to different sociodemographic variables. Distress and fear related to COVID-19 and following reassurance-seeking behavior were prominent during the pandemic. However, even after the end of the acute phase, due to continued uncertainty about protection from COVID-19, psychological concerns surrounding COVID-19 persisted.</p><p><strong>Aim: </strong>To evaluate coronavirus-related psychological distress, fear, reassurance seeking, and their correlation with personality factors.</p><p><strong>Materials and methods: </strong>A total of 727 individuals were taken from the community from May 2022 to October 2022 and were requested to fill out a Google Form online comprising basic sociodemographic details and the following scales: COVID-19-related psychological distress in healthy public (CORPD), Fear of COVID-19 Scale (FCV-19S), Coronavirus Reassurance-Seeking Behavior Scale, and Big Five Personality Inventory. The information was then charted, tabulated, and statistically analyzed.</p><p><strong>Results: </strong>The levels of COVID-19-related psychological distress and fear were comparable to the levels present during a pandemic. Psychological distress, fear, and reassurance-seeking were positively correlated with each other. Females were vulnerable to fear. Younger age was associated with reassurance seeking. Extraversion personality traits positively predicted fear about COVID-19, while conscientiousness and openness negatively predicted fear. Agreeableness positively predicted reassurance-seeking behavior.</p><p><strong>Conclusion: </strong>Even after the declaration of the end of the COVID-19 pandemic and the return to the regular daily routine, people have COVID-19-related distress and fear in their minds. This indicates the need for continuation of mental health programs addressing these psychological issues related to COVID-19.</p>","PeriodicalId":13534,"journal":{"name":"Industrial Psychiatry Journal","volume":"35 2","pages":"217-222"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13561481/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148944744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ganglioglioma masquerading as childhood depression.","authors":"Priya Kathfar, Varchasvi Mudgal, Priyash Jain","doi":"10.4103/ipj.ipj_273_25","DOIUrl":"10.4103/ipj.ipj_273_25","url":null,"abstract":"","PeriodicalId":13534,"journal":{"name":"Industrial Psychiatry Journal","volume":"35 2","pages":"240-241"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13561472/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148944692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Type AD Personality: A composite personality construct and its association with coronary artery disease.","authors":"Usri Sengupta, Amool Ranjan Singh, Hemant Narayan Ray","doi":"10.4103/ipj.ipj_268_25","DOIUrl":"10.4103/ipj.ipj_268_25","url":null,"abstract":"<p><strong>Background: </strong>The prevalence of coronary artery disease (CAD) in India is about 7% to 13%. CAD may exacerbate psychological distress and raise the risk of cardiac event following surgeries.</p><p><strong>Aim: </strong>To study the impact of personality type on psychological distress in individuals having CAD who underwent coronary angioplasty.</p><p><strong>Materials and methods: </strong>This cross-sectional correlational study was carried out in the Cardiology department of a tertiary care hospital on 40 patients who had undergone coronary angioplasty for CAD. Data were collected during a period of 3 to 10 months, post coronary angioplasty. The subjects were interviewed and evaluated with the Type A/B Behaviour Pattern Scale, Type D Scale-14, Hospital Anxiety and Depression scale, Perceived Stress Scale, Locus of Control Scale, and Subjective Well-Being Inventory. Spearman's Rank Correlation coefficient assessed the association between personality and psychological distress. Kruskal-Wallis test with <i>post hoc</i> analysis studied the relative impact of the Personality Type on psychological distress.</p><p><strong>Results: </strong>Among 40 participants, 21 people had Type AD personality, 8 people had Type A personality, and 11 people had Type D personality. It was found that people who have a combination of Type A and Type D personality characteristics (Type AD personality) have more psychological distress than those having Type A or Type D personality alone, thereby demonstrating the relative impact of Type AD personality on psychological distress.</p><p><strong>Conclusion: </strong>The study shows the interrelation between personality and cardiac event and delineates the importance of considering the psychological distress as a major risk factor for CAD, especially after coronary angioplasty.</p>","PeriodicalId":13534,"journal":{"name":"Industrial Psychiatry Journal","volume":"35 2","pages":"213-216"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13561486/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148944712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}