Industrial Psychiatry Journal最新文献

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Stress of postgraduate medical students - A myth or a reality? 医学研究生的压力——神话还是现实?
Industrial Psychiatry Journal Pub Date : 2025-01-01 Epub Date: 2025-01-15 DOI: 10.4103/ipj.ipj_298_24
Himadri Bal, Tanvi Nijhawan
{"title":"Stress of postgraduate medical students - A myth or a reality?","authors":"Himadri Bal, Tanvi Nijhawan","doi":"10.4103/ipj.ipj_298_24","DOIUrl":"https://doi.org/10.4103/ipj.ipj_298_24","url":null,"abstract":"","PeriodicalId":13534,"journal":{"name":"Industrial Psychiatry Journal","volume":"34 1","pages":"132"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12077644/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144077625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Workplace violence in the healthcare setting and its psychological impact on healthcare workers. 卫生保健环境中的工作场所暴力及其对卫生保健工作者的心理影响
Industrial Psychiatry Journal Pub Date : 2025-01-01 Epub Date: 2025-02-06 DOI: 10.4103/ipj.ipj_375_24
Reuben Praharsh Kumar, Wincy Verghese, Divya Hegde, Smitha Lamiya Rasquinha, Rahul M Rao, Ajay Kumar
{"title":"Workplace violence in the healthcare setting and its psychological impact on healthcare workers.","authors":"Reuben Praharsh Kumar, Wincy Verghese, Divya Hegde, Smitha Lamiya Rasquinha, Rahul M Rao, Ajay Kumar","doi":"10.4103/ipj.ipj_375_24","DOIUrl":"https://doi.org/10.4103/ipj.ipj_375_24","url":null,"abstract":"<p><strong>Background: </strong>Workplace violence (WPV) among healthcare workers (HCWs) poses a significant burden globally. Various studies have estimated the prevalence and characteristics of WPV, but few have assessed the impact in terms of the mental health of HCWs in the aftermath.</p><p><strong>Aim: </strong>To study the prevalence of WPV and its psychological impact on HCWs. In addition, we aimed to suggest strategies that can be implemented to prevent the overpowering burden of WPV.</p><p><strong>Materials and methods: </strong>We used a standardized questionnaire developed by the International Labor Office to assess WPV, General Health Questionnaire (GHQ-12) to assess psychological distress, and a self-reported sleep quality scoring.</p><p><strong>Results: </strong>The study included 268 participants among which 43.7% reported having experienced WPV in the last 12 months, with 42.5% reporting verbal violence and 3.4% reporting physical violence incidents. Working in emergency services showed a significant association with experiencing verbal violence. There is also an underreporting of incidents of WPV. Among the psychological parameters, distress is significantly higher for both verbal and physical violence, and participants who faced physical violence had significantly lower sleep quality. Prevention strategies including adequate patient counseling, better communication, improved security, and stricter laws can be implemented to reduce violence.</p><p><strong>Conclusion: </strong>WPV in healthcare is very common in India with not only high prevalence rates but also a significant psychological burden. There is a need to develop better laws and implement policies to ensure a safe and healthy workplace for HCWs.</p>","PeriodicalId":13534,"journal":{"name":"Industrial Psychiatry Journal","volume":"34 1","pages":"45-52"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12077643/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144077574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Group intervention for intimate partner violence: Manual development and content validation. 亲密伴侣暴力的团体干预:手册开发和内容验证。
Industrial Psychiatry Journal Pub Date : 2025-01-01 Epub Date: 2025-04-18 DOI: 10.4103/ipj.ipj_362_24
Chinnadurai Periyasamy, Gitanjalai Narayanan, Arun Kandasamy, Sinu Ezhumalai
{"title":"Group intervention for intimate partner violence: Manual development and content validation.","authors":"Chinnadurai Periyasamy, Gitanjalai Narayanan, Arun Kandasamy, Sinu Ezhumalai","doi":"10.4103/ipj.ipj_362_24","DOIUrl":"https://doi.org/10.4103/ipj.ipj_362_24","url":null,"abstract":"<p><strong>Background: </strong>Group intervention is highly effective for survivors of IPV. There are fewer interventions available for intimate partner violence in addiction treatment settings in India.</p><p><strong>Aim: </strong>To develop and validate the group intervention module for women survivors of IPV.</p><p><strong>Materials and methods: </strong>The group intervention manual was developed by assessing the psychosocial needs of survivors (n = 20) of intimate partner violence and subject experts' opinions (n = 7). The manual was validated using the content validation index and kappa value.</p><p><strong>Results: </strong>The components of the group intervention manual were developed for women survivors of IPV who were seeking treatment for their spouse's alcohol dependence. The group intervention components include sharing the experience of intimate partner violence, understanding the impact of IPV, psychoeducation regarding alcohol dependence and the treatment process for alcohol dependence, imparting social skills, safety plans, and self-care for the IPV survivors and their children, crisis intervention, and resource mapping. The content validation score of the group manual (I-CVI) is 0.79. The kappa value of 0.0078 indicates that the manual's content validity is excellent.</p><p><strong>Conclusion: </strong>The group intervention module was validated by the mental health professionals working in the area of partner violence, and final manual has a good content validation score (0.79). The group work manual results indicate that it is feasible to apply in the de-addiction setting in India. Future studies should focus on the large number of population and should look in to address the perpetrated and couple-based intervention for the survivors of IPV.</p>","PeriodicalId":13534,"journal":{"name":"Industrial Psychiatry Journal","volume":"34 1","pages":"61-66"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12077619/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of electroconvulsive therapy on serum brain derived neurotrophic factor, serum interleukin-6, and serum cortisol levels in patients with treatment refractory schizophrenia. 电休克治疗对难治性精神分裂症患者血清脑源性神经营养因子、血清白细胞介素-6和血清皮质醇水平的影响
Industrial Psychiatry Journal Pub Date : 2025-01-01 Epub Date: 2025-04-18 DOI: 10.4103/ipj.ipj_422_24
Nikhil Gurjar, Jitendra Jeenger, Ashish Sharma, Devendra M Mathur
{"title":"Effects of electroconvulsive therapy on serum brain derived neurotrophic factor, serum interleukin-6, and serum cortisol levels in patients with treatment refractory schizophrenia.","authors":"Nikhil Gurjar, Jitendra Jeenger, Ashish Sharma, Devendra M Mathur","doi":"10.4103/ipj.ipj_422_24","DOIUrl":"https://doi.org/10.4103/ipj.ipj_422_24","url":null,"abstract":"<p><strong>Background: </strong>Schizophrenia (SCZ) is a severe psychiatric disorder characterized by cognitive dysfunction and persistent psychotic symptoms. Treatment refractory schizophrenia (TRS), resistant to conventional antipsychotics, presents significant challenges. Electroconvulsive therapy (ECT) is effective for TRS, but its biological mechanisms remain unclear. Biomarkers such as brain-derived neurotrophic factor (BDNF), interleukin-6 (IL-6), and cortisol, linked to neuroplasticity, immune modulation, and stress regulation, may help elucidate ECT's therapeutic effects.</p><p><strong>Aim: </strong>This study evaluated the impact of ECT on serum levels of BDNF, IL-6, and cortisol in TRS patients and explored the relationship between these biomarkers and symptom improvement.</p><p><strong>Materials and methods: </strong>A prospective study was conducted at a tertiary care hospital from 2018 to 2020. Thirty-five TRS patients (aged 18-60 years) underwent symptom severity assessments using the positive and negative syndrome scale (PANSS) pre- and post-ECT. Serum levels of BDNF, IL-6, and cortisol were measured using enzyme-linked immunosorbent assays (ELISA). ECT was administered bilaterally in 4-7 sessions per patient. Paired t-tests and Spearman's correlation were used for statistical analysis.</p><p><strong>Results: </strong>ECT significantly reduced positive (<i>P</i> < 0.001), general (<i>P</i> < 0.001), and total PANSS scores (<i>P</i> < 0.001), with modest reductions in negative symptoms (<i>P</i> < 0.001). Serum IL-6 levels decreased significantly post-ECT (<i>P</i> = 0.018), while changes in BDNF (<i>P</i> = 0.198) and cortisol (<i>P</i> = 0.403) were not statistically significant. Increased BDNF levels positively correlated with reduced positive symptoms (<i>P</i> = 0.041), while decreased IL-6 levels correlated with symptom improvement (<i>P</i> = 0.045).</p><p><strong>Conclusion: </strong>ECT reduces symptom severity in TRS, with significant modulation of IL-6 and potential involvement of BDNF in positive symptom improvement. These findings highlight immune and neuroplastic pathways as mechanisms of ECT efficacy and suggest biomarkers for treatment response.</p>","PeriodicalId":13534,"journal":{"name":"Industrial Psychiatry Journal","volume":"34 1","pages":"39-44"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12077616/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144078062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Integrating spirituality into the treatment of substance use disorders: A holistic approach to recovery. 将精神融入物质使用障碍的治疗:一种全面的康复方法。
Industrial Psychiatry Journal Pub Date : 2025-01-01 Epub Date: 2025-02-06 DOI: 10.4103/ipj.ipj_260_24
Victor Ajluni
{"title":"Integrating spirituality into the treatment of substance use disorders: A holistic approach to recovery.","authors":"Victor Ajluni","doi":"10.4103/ipj.ipj_260_24","DOIUrl":"https://doi.org/10.4103/ipj.ipj_260_24","url":null,"abstract":"","PeriodicalId":13534,"journal":{"name":"Industrial Psychiatry Journal","volume":"34 1","pages":"142-143"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12077615/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144077056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Psychometric evaluation of smartphone addiction scale - short version (SAS-SV) among young adults of India. 印度年轻人智能手机成瘾量表(SAS-SV)的心理测量学评估
Industrial Psychiatry Journal Pub Date : 2025-01-01 Epub Date: 2025-02-06 DOI: 10.4103/ipj.ipj_336_24
George Felix, Manoj K Sharma, Nitin Anand, Binukumar Bhaskarapillai, Kalpana Srivastava
{"title":"Psychometric evaluation of smartphone addiction scale - short version (SAS-SV) among young adults of India.","authors":"George Felix, Manoj K Sharma, Nitin Anand, Binukumar Bhaskarapillai, Kalpana Srivastava","doi":"10.4103/ipj.ipj_336_24","DOIUrl":"https://doi.org/10.4103/ipj.ipj_336_24","url":null,"abstract":"<p><strong>Background: </strong>Although smartphones have considerable utility, they also have addiction potential. The early detection of problematic smartphone use (PSU) can have significant implications for managing its psychosocial consequences. Smartphone Addiction Scale - Short Version (SAS-SV), initially developed for South Korean adolescents, has emerged as a reliable measure for adults across countries. However, SAS-SV continues to be used unvalidated in India.</p><p><strong>Aim: </strong>To evaluate the psychometric properties of SAS-SV for the Indian adult population.</p><p><strong>Materials and methods: </strong>Content validation of SAS-SV was done by 10 experts, followed by data collection for validation using a cross-sectional design from 434 participants (<i>M</i> <sub>age</sub> = 25.4; <i>SD</i> <sub>age</sub> = 2.6; 58.8% females). The datasheet consisted of a sociodemographic questionnaire and SAS-SV. Statistical analyses comprised confirmatory factor analysis (CFA), exploratory factor analysis (EFA), reliability analyses, percentiles, and evaluation of sociodemographic variables.</p><p><strong>Results: </strong>SAS-SV's content validity index was 0.93, and item wordings were adjusted after experts' feedback. CFA did not show good fit indices; hence, EFA was used, which explained 44% of the variance from a unifactorial model. Cronbach's alpha was 0.85, McDonald's Omega was 0.86, and test-retest reliability was 0.81. There were no significant PSU differences in gender, marital status, and occupational status. Higher PSU was associated with lower age, lower education, nuclear family, and more hours of smartphone usage.</p><p><strong>Conclusion: </strong>The current study established the psychometric properties of SAS-SV for the Indian adult population. SAS-SV can be used for assessment and treatment monitoring of PSU.</p>","PeriodicalId":13534,"journal":{"name":"Industrial Psychiatry Journal","volume":"34 1","pages":"53-60"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12077639/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144077621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sublingual use of atropine eye drops for the treatment of clozapine induced sialorrhea. 舌下使用阿托品滴眼液治疗氯氮平引起的唾液漏。
Industrial Psychiatry Journal Pub Date : 2025-01-01 Epub Date: 2025-01-15 DOI: 10.4103/ipj.ipj_352_24
Anirban Saha, Ayush Singh, Neethu K Nandan, Shrayasi Das, Aditya Somani
{"title":"Sublingual use of atropine eye drops for the treatment of clozapine induced sialorrhea.","authors":"Anirban Saha, Ayush Singh, Neethu K Nandan, Shrayasi Das, Aditya Somani","doi":"10.4103/ipj.ipj_352_24","DOIUrl":"https://doi.org/10.4103/ipj.ipj_352_24","url":null,"abstract":"<p><p>Clozapine is the drug of choice for patients with treatment-resistant schizophrenia. However, it has a variety of adverse effects. Sialorrhea is a bothersome side effect that can have an impact on both medical and psychosocial aspects. There is limited literature on the use of 1% atropine eye drops sublingually for the treatment of clozapine-induced sialorrhea (CIS). In this case series, we report three patients of CIS treated successfully with 1% atropine eye drops given sublingually.</p>","PeriodicalId":13534,"journal":{"name":"Industrial Psychiatry Journal","volume":"34 1","pages":"123-125"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12077623/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144077629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A qualitative study on employment opportunities and social inclusion of persons with mental illness: Lived experiences. 精神疾病患者就业机会与社会包容的质性研究:生活经验。
Industrial Psychiatry Journal Pub Date : 2025-01-01 Epub Date: 2025-04-18 DOI: 10.4103/ipj.ipj_364_24
Sushma Kumari, Manoj Kumar
{"title":"A qualitative study on employment opportunities and social inclusion of persons with mental illness: Lived experiences.","authors":"Sushma Kumari, Manoj Kumar","doi":"10.4103/ipj.ipj_364_24","DOIUrl":"https://doi.org/10.4103/ipj.ipj_364_24","url":null,"abstract":"<p><strong>Background: </strong>Across the Globe, including in India, significant changes have occurred in the Mental health policies, programs, and schemes for Persons With Mental Illness (PWMI). Gradually, people are becoming aware of the nature of mental illness. Many Bollywood actors are coming forward to share their mental health conditions and show how successfully they handle them. Despite all these efforts, even the recovered or recovering PWMI are still being denied their basic fundamental human rights, especially regarding selection and continuation of gainful employment along with social inclusion at the community level.</p><p><strong>Aim: </strong>Considering the above, the present study aimed to understand the lived experiences regarding the opportunities available for employment and social inclusion among PWMI in India.</p><p><strong>Material and methods: </strong>The present study was based on a qualitative design. Patients who maintained well on treatment and had capabilities to be included in gainful employment, but were still facing difficulties in securing and maintaining regular employment, and faced discrimination in social inclusion in society, were assessed in detail by in-depth interviews after obtaining their due consent.</p><p><strong>Results: </strong>The main themes that emerged from the study were related to their own experience of the journey of recovery in terms of getting the opportunity for full participation in employment or to be acknowledged as a valuable person in their society rather than a patient.</p><p><strong>Conclusion: </strong>The present study's findings would enhance the understanding among health professionals, policy-makers, and community persons to plan and develop supportive programs/ social welfare services that treat PWMI as persons and involve them as productive members of society.</p>","PeriodicalId":13534,"journal":{"name":"Industrial Psychiatry Journal","volume":"34 1","pages":"76-81"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12077645/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144078046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Turner's syndrome with schizophrenia: A case report. 特纳氏综合症和精神分裂症
Industrial Psychiatry Journal Pub Date : 2025-01-01 Epub Date: 2023-08-11 DOI: 10.4103/ipj.ipj_34_23
V Pooja, Bhushan Chaudhari, Suprakash Chaudhury, Daniel Saldanha
{"title":"Turner's syndrome with schizophrenia: A case report.","authors":"V Pooja, Bhushan Chaudhari, Suprakash Chaudhury, Daniel Saldanha","doi":"10.4103/ipj.ipj_34_23","DOIUrl":"10.4103/ipj.ipj_34_23","url":null,"abstract":"","PeriodicalId":13534,"journal":{"name":"Industrial Psychiatry Journal","volume":" ","pages":"144-145"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12077620/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44857745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Low dose baclofen and standard dose acamprosate had comparable changes in brain glutamate, brain Gamma amino butyric acid (GABA) and craving among patients with alcohol dependence syndrome: A 1H-MRS based open label randomized study. 低剂量巴氯芬和标准剂量阿坎前列酸在酒精依赖综合征患者中脑谷氨酸、脑γ氨基丁酸(GABA)和渴望的变化相当:一项基于h - mrs的开放标签随机研究。
Industrial Psychiatry Journal Pub Date : 2025-01-01 Epub Date: 2025-04-18 DOI: 10.4103/ipj.ipj_187_23
Akhil Kesan, Pranjal Dey, Sourav Khanra, Samiksha Singhai, Monalisa Boro
{"title":"Low dose baclofen and standard dose acamprosate had comparable changes in brain glutamate, brain Gamma amino butyric acid (GABA) and craving among patients with alcohol dependence syndrome: A 1H-MRS based open label randomized study.","authors":"Akhil Kesan, Pranjal Dey, Sourav Khanra, Samiksha Singhai, Monalisa Boro","doi":"10.4103/ipj.ipj_187_23","DOIUrl":"https://doi.org/10.4103/ipj.ipj_187_23","url":null,"abstract":"<p><strong>Background: </strong>Understanding of the mechanism of action of Baclofen as anticraving inalcohol dependence syndrome (ADS) is limited.</p><p><strong>Aim: </strong>Our study aimed to examine and compareearly changes in brain glutamate and GABA with Baclofen and Acamprosate among patients with alcohol dependence syndrome.</p><p><strong>Material and methods: </strong>Forty patients with ADS were recruited with purposive sampling and were randomized into two groups using computer-generated randomization. At the end of detoxification (CIWA-Ar <10) brain glutamate and GABA were measured with proton magnetic resonance spectroscopy (1H-MRS) in the anterior cingulate cortex (ACC) of the brain along with a measure of craving (PACS). Either Acamprosate or Baclofen was started. After 25 days of starting Baclofen or Acamprosate brain glutamate and brain GABA using 1H-MRS and PACS measures were repeat measured.</p><p><strong>Results: </strong>Both groups had shown comparable changes in brain glutamate (<i>F</i> = 0.01, <i>P</i> = 0.92, <i>ηp2</i> = 0.00) and GABA (<i>F</i> = 0.29, 26 <i>P</i> = 0.59, <i>ηp2</i> = 0.008) and craving (<i>F</i> = 0.08, <i>P</i> = 0.77, <i>ηp2</i> = 0.002) over time. Baclofen and Acamprosate showed a differential relation with the clinical characteristics of participants.</p><p><strong>Conclusion: </strong>Our study has shown comparable changes in Glutamate and GABA during the early post-detoxification period both for baclofen and acamprosate. Effects of baclofen and acamprosate might correlate differently with the clinical profile of alcohol dependence syndrome which would help in choosing a particular anticraving medication.</p>","PeriodicalId":13534,"journal":{"name":"Industrial Psychiatry Journal","volume":"34 1","pages":"25-31"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12077627/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144077424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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