Indian journal of applied research最新文献

{"title":"EPIDERMOID CYST IN UTERINE CERVIX- A RARE AND UNUSUAL LOCATION","authors":"Farha Naaz, Asfiya Fatima, Idrees Akhtar Afroze","doi":"10.36106/ijar/9602538","DOIUrl":"https://doi.org/10.36106/ijar/9602538","url":null,"abstract":"Cervical epidermoid cysts and uncommon benign cystic lesions were identied in a 50-year-old woman. The patient\u0000presented with heavy menstrual bleeding and lower abdominal pain, and after initial treatment with endometrial biopsy\u0000and hemostatic uterine curettage, a total abdominal hysterectomy with bilateral salpingo-oophorectomy was performed. The gross examination of\u0000the specimen revealed a hypertrophied cervix with a cyst lled with grey-white substance, as well as a polypoidal mass in the fundus and\u0000intramural broids. Histopathological examination conrmed the diagnosis of a cervical epidermoid cyst as an incidental nding. Squamous\u0000metaplasia was conned to the cervical mucosa. The precise etiology remains unclear, but post-parturient implantation of vestigial embryonic\u0000tissue might be a contributing factor as there is no other associated etiology in this case. This case report emphasizes the importance of considering\u0000epidermoid cysts in the differential diagnosis of cervical masses and highlights the need for further research to better understand the formation and\u0000management of these rare cysts.","PeriodicalId":13502,"journal":{"name":"Indian journal of applied research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141058396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"SLEEP QUALITY, QUALITY OF LIFE AND GLYCEMIC CONTROL: COMPARISON BETWEEN RURAL AND URBAN TYPE 2 DIABETIC PATIENTS","authors":"Dhriti. Y, Dharuni. R, Arun Udayaraj K, Sowmya. P","doi":"10.36106/ijar/8603055","DOIUrl":"https://doi.org/10.36106/ijar/8603055","url":null,"abstract":"Type 2 Diabetes Mellitus is a pandemic causing enormous burden in terms of morbidity and mortality. Life style\u0000modication is the rst step in the management of Diabetes. Sleep quality and other Quality of life(QoL) indices are often\u0000neglected. There is a vast difference in the life style of urban and rural population and may inuence the course of Diabetes Mellitus and its\u0000management.Aim of the study was to (1). Examine sleep quality, QoL and glycemic control among rural and urban diabetic individuals. (2).\u0000Compare sleep quality, QoL and glycemic control between rural and urban diabetic individuals. In this study, 110 diabetic patients were grouped\u0000as rural and urban categories. Sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI). WHOQOL-Bref was used to\u0000assessQoL. HbA1c was estimated using turbidimetry kit method. The mean HbA1c levels were 8.1± 2.6 in urban and 7.7 ± 1.7 among rural\u0000diabetics. Mean sleep score of the urban diabetics was 12.3 ± 6.7 and was 11.4 ± 4.8 in rural diabetics. QOL good scores were 68.3%, 76.7%,\u000086.7% and 76.7% among urban diabetics and 88%, 70%, 90% and 98% correspondingly in rural diabetics. This study concluded that the rural\u0000diabetic patients had better glycemic control. They had better sleep scores and QoL scores in all domains except social domain. The better\u0000glycemic control seen may be due to life style and environmental differences.","PeriodicalId":13502,"journal":{"name":"Indian journal of applied research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141023942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"TURRITOXIN PAIAA SOURCE OF NOVEL ANTIMICROBIAL PEPTIDES AGAINST A. BAUMANNII","authors":"Mugdha Belwalkar, Anushka Chitale, Varsha Shukla, A. Lokur","doi":"10.36106/ijar/0800954","DOIUrl":"https://doi.org/10.36106/ijar/0800954","url":null,"abstract":"Antimicrobial Resistance (AMR) has been a silent pandemic. Newer antibiotics are required to treat drug-resistant\u0000pathogens. Antimicrobial peptides (AMPs) are promising next-generation antibiotics that are naturally produced in all\u0000living organisms. They are crucial components of the natural resistance framework of an organism. Small cationic peptides of 10-60 amino acid\u0000lengths have been successfully used as antibiotics. Marine ecosystems have an immense diversity of organisms and microorganisms that interact\u0000with each other, and thus have unique defense mechanisms. Marine cone snails are an untapped source of small, cationic AMPs. These snails\u0000secrete various proteinaceous venoms to deal with predators and preys. These cone snail venoms remain unexplored for their potential as\u0000antimicrobial peptides. The structural analysis of the venomous protein, Turritoxin PaIAa, from cone snails showed a high content of amino acids\u0000commonly found in AMPs. However, it did not exhibit any antibacterial activity. This protein was further investigated by overlap fractionation to\u0000identify hidden antimicrobial and cell-penetrating peptides. The unique peptide stretches obtained from PaIAa were evaluated against the toppriority ESKAPE pathogens. All peptides were active against A. baumannii. All peptides had cell-penetrating properties. These AMP candidates\u0000also showed promising physical, physicochemical, and pharmacokinetic properties. The AMP candidates identied in this study can be further\u0000evaluated by in vitro and in vivo testing.","PeriodicalId":13502,"journal":{"name":"Indian journal of applied research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141025770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PLAY SKILLS AND DEVELOPMENTAL TRAJECTORY IN PRESCHOOL CHILDREN WITH MILD TO MODERATE AUTISM SPECTRUM DISORDERS","authors":"Shailaja Jaywant, Tushika Ganesh, Hrucha Samir Varadkar, Ashwini Maruti Ghode, Priya Ingale","doi":"10.36106/ijar/0903667","DOIUrl":"https://doi.org/10.36106/ijar/0903667","url":null,"abstract":"Autism Spectrum Disorder (ASD) is characterized by decits in social interaction, impaired communication abilities,\u0000restricted and repetitive behaviors and reduced interest and engagement in social activities, all of which impact their\u0000developmental and play skills. The purpose of this study was to observe the play skills and developmental trajectory, as well as to explore their\u0000correlation, among children diagnosed with mild to moderate ASD.\u0000The play abilities of twenty preschool children, with ages ranging from 2 to 6 years, who have been diagnosed with mild to moderate Autism\u0000Spectrum Disorder, were assessed using the Knox Preschool Play scale. The assessment of developmental trajectory was conducted utilizing the\u0000Ages & Stages Questionnaire-III (ASQIII). The relationship between them was examined through the application of the Pearson correlation test.\u0000The play skills affected to moderate level scores ranging from -0.47 to 0.75 out of maximum score 2 and the developmental domains such as\u0000communication, ne motor skills, problem solving abilities & personal social development showed moderate to severe involvement scoring\u0000between 8.75 to 28.36 out of maximum score of 60 in each domain.\u0000Space and Material Management displayed a moderate level of impairment. There is a notable impairment in both participation and\u0000pretense/symbolic play. The impact on the development of personal social skills and problem-solving abilities was notable when compared to\u0000children with typical development. This suggests a deviation from the usual trajectory of overall development and play capabilities. Researchers\u0000have noted a moderate positive correlation between material management and the development of both ne motor skills and problem-solving\u0000ability. Participation has been observed to exhibit a similar correlation with ne motor skills. The signicance of executive functions, planning,\u0000and ne motor development in the development of play skills is emphasized by these ndings, suggesting the necessity of Occupational Therapy\u0000intervention for child development.","PeriodicalId":13502,"journal":{"name":"Indian journal of applied research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141030744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A CASE OF UNMASKING A HIDDEN CULPRIT: DRUG INTERFERENCE IN BILIRUBIN TESTING","authors":"Arpita Mishra","doi":"10.36106/ijar/7100897","DOIUrl":"https://doi.org/10.36106/ijar/7100897","url":null,"abstract":"This report sheds light on a potential challenge in clinical chemistry\u0000testing - how medications can interfere with test results, leading to\u0000misinterpretations","PeriodicalId":13502,"journal":{"name":"Indian journal of applied research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141025947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"WINE BOTTLE WOES: THE MORBID INTERSECTION OF NEAR HANGING AND MESENTERIC LACERATION: A CASE REPORT","authors":"Anjesh Mittal, Richa Gupta, Umer Bin Abdul Aziz, Ajay Singh","doi":"10.36106/ijar/9200162","DOIUrl":"https://doi.org/10.36106/ijar/9200162","url":null,"abstract":"We present a case report of a fatal mesenteric injury resulting from a crushed wine bottle following a near hanging\u0000incident. The deceased, a 23 -year-old male, was found hanging from a rope in his residence after consuming a\u0000considerable amount of alcohol. Upon investigation, it was revealed that the individual had fallen from the hanging position, leading to the wine\u0000bottle he was holding being crushed against his abdomen. The blunt force trauma from the shattered bottle caused extensive mesenteric injury,\u0000resulting in hemorrhagic shock and subsequent death. This case underscores the potential for severe and unexpected complications in cases of\u0000alcohol-related self-harm, highlighting the importance of thorough forensic examination and consideration of unusual mechanisms of injury.","PeriodicalId":13502,"journal":{"name":"Indian journal of applied research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141047721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"IMPACT OF RECENT EDUCATION REFORMS ON THE OUTCOMES OF STUDENT OF DIPLOMA IN PHARMACY IN PUNJAB","authors":"Sukhpreet Kaur, Ravi Shankar Kumar","doi":"10.36106/ijar/4901542","DOIUrl":"https://doi.org/10.36106/ijar/4901542","url":null,"abstract":"Over the past two decade the role of pharmacist is evolved from that of compounder and dispenser of medicines to experts\u0000on medicines. The involvement of pharmacist has increased within multidisciplinary health care system. Keeping in view\u0000the evolving roles of Pharmacist PCI has introduced the new syllabus after a gap of 30 years for Diploma in Pharmacy. This study aims to Aim:\u0000assess the impact of recent education reforms and changes in curriculum of Diploma in Pharmacy on the outcomes of students in Punjab.\u0000Methodology: A literature search was conducted to nd the recent reforms in pharmacy education and evaluation system. All the colleges of\u0000Punjab under Punjab State Board of Technical Education and Industrial Training (PSBTE & IT) were included in the study. The result of Diploma\u0000in Pharmacy under PSBTE & IT was available in open domain through PSBTE & IT website. There are 105 Result: colleges running course in\u0000Diploma in Pharmacy under the aegis of PSBTE & IT and PCI. In past year (academic year 2022-2023), PSBTE & IT has implemented various\u0000regulation reforms. The PCI has implemented new curriculum for Diploma in Pharmacy. This year 5477 students appeared for 2nd year\u0000examination of Diploma in Pharmacy and only 19.11% students passed in second year examination. There were 5 colleges in Punjab where the\u0000result was 100% and 20% colleges in Punjab where none of the students passed in Diploma in Pharmacy (2nd yr) examination. It Conclusion:\u0000can be concluded that regulation reforms implemented by PSBTE& IT has affected the examination system for Diploma in Pharmacy students\u0000and pass percentage of students have considerably decreased","PeriodicalId":13502,"journal":{"name":"Indian journal of applied research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141048302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A RARE CASE OF PLACENTA INCRETA – CASE REPORT","authors":"Shweta S Nemagoud, Ravi Raval, Pooja B Dahiphale","doi":"10.36106/ijar/3001635","DOIUrl":"https://doi.org/10.36106/ijar/3001635","url":null,"abstract":"In these years with the raise in cesarean section rates, the frequency of PAS cases has risen. It has accounted for 33–50% of\u0000all emergency peripartum or obstetric hysterectomies. PAS is an obstetric emergency associated with a high maternal\u0000morbidity and mortality rate, presenting unique challenges in its diagnosis and management. We present a 24-year-old third gravida with previous\u00002 LSCS, who presented with PV bleeding, being unaware of pregnancy. This 22week pregnancy with previous 2 LSCS with placenta previa with\u0000active PV bleed, was managed surgically with obstetric hysterectomy as per intraoperative evidence and unstable vitals with severe hemorrhagic\u0000shock. Post operative recovery and follow-up was uneventful.","PeriodicalId":13502,"journal":{"name":"Indian journal of applied research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141044223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"BODY COMPOSITION DISTRIBUTION IN MIDDLE-AGED WORKING WOMEN AND HOMEMAKERS- A COMPARISON","authors":"Nutan Nutan, Sushma Ghildyal","doi":"10.36106/ijar/2709162","DOIUrl":"https://doi.org/10.36106/ijar/2709162","url":null,"abstract":"Background- The last few years of life are important for changes in body fat and weight increases. Increased central body\u0000fat distribution and weight gain are linked to the body transformation. Objective-determination of difference in middleaged working women and homemaker's body composition. A total of 60 working and homemakers were sele Methodology- cted from Varanasi.\u0000Further, these 60 working and homemaker women were divided into two groups. Every group had 30 working women and 30 homemakers. The\u0000subjects were 40–55. BMI, visceral fat, and subcutaneous fat were assessed using a BIA body composition monitor. Mean and standard deviation\u0000were used for all obesity factors. Unpaired-t Test was used with signicance set at (p<0.05). shows Result- the difference in BMI(0.030, p<0.05),\u0000(t58=-2.232), Visceral fat(.048,p<0.05), (t58=2.019) subcutaneous fat (.042,p<0.05),(t58=2.08) and Protein percentage (p>0.05) here is the\u0000signicant in body fat distribution of middle age working women and homemakers. According to the st Conclusion- udy ndings, working\u0000women and homemakers have differed signicantly in BMI, Visceral fat and Subcutaneous fat.","PeriodicalId":13502,"journal":{"name":"Indian journal of applied research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141024343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"SWEDANA THERAPY A HOPE FOR MEDOPRADOSHAJA VIKARA W.S.R. CHRONIC KIDNEY DISEASE (CKD) PATIENTS","authors":"Dipti Mishra, Abhiranjan Abhiranjan, Sujeet Kumar","doi":"10.36106/ijar/4300707","DOIUrl":"https://doi.org/10.36106/ijar/4300707","url":null,"abstract":"Swedana (sudation) therapy is a process which has a dual role in panchkarma as well as pradhan karma in relevance to\u0000panchkarma and the treatment of various vata-kaphaja and medopradoshaja vikara. Swedana helps to relief stiffness\u0000heaviness and coldness of the body and makes the body to perspire. It removes toxins from the body through hair follicles present all over the skin\u0000.The perspiration brought about by the swedana is more than the normal. Swedana is preventive, supportive as well as therapeutic. Acharya\u0000charak has mentioned the root of origin of swedavaha srotas (channels) lies in Meda (fat, lipids, Adipose tissue) and lomakoop (minute pores of\u0000the skin located around base of hair follicles). Sweda is considered to be excreta (Mala) of meda dhatu. The root of origin of medovaha srotas\u0000(channels) are Vrikka (kidney) and vapvahana(peritoneal membrane). The Vrikka (kidney) is originated from prasada bhag of Rakta (Blood) and\u0000meda. In Chronic kidney disease (CKD), the hemodynamics of the kidney is hampered which leads to accumulation of toxins and unltered\u0000excretory wastes. So with the help of swedana the hemodynamics of kidney and the body is improved which facilitates the expulsion of\u0000accumulated toxins through activation of sweat glands to produce more sweat. It causes apana vata anulomana which further facilitates\u0000micturition. In this article you will come to know the relevance of swedana in chronic kidney disease (CKD) patients.","PeriodicalId":13502,"journal":{"name":"Indian journal of applied research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141047591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}