IEEE Transactions on Neural Systems and Rehabilitation Engineering最新文献

{"title":"Exploring the Feasibility of Bidirectional Spinal Cord Machine Interface through Sensing and Stimulation of Axonal Bundles.","authors":"Yu Tung Lo, Alessandro Maggi, Kevin Wu, Hui Zhong, Wooseong Choi, Thanh Dat Nguyen, Aidin Abedi, Kofi Agyeman, Sofia Sakellaridi, Victor Reggie Edgerton, Evgeniy Kreydin, Darrin Lee, Constantine Sideris, Charles Y Liu, Vassilios N Christopoulos","doi":"10.1109/TNSRE.2025.3570324","DOIUrl":"https://doi.org/10.1109/TNSRE.2025.3570324","url":null,"abstract":"<p><p>Spinal cord injury (SCI) patients experience long-term deficits in motor and sensory functions. While brain-machine interface (BMI) has shown great promise for restoring neurological functions after SCI, spinal cord-machine interface (SCMI) offers unique advantages, such as more defined somatotopy and the compact organization of neural elements in the spinal cord. In the current study, we aim to demonstrate the feasibility of sensing and evoking compound action potentials (CAPs) via electrode implantation in spinal cord axonal bundles, an essential prerequisite for advancing toward SCMI development. To do so, we designed microelectrode arrays (MEA) optimized for recording and stimulation in the spinal cord. For sensory mapping, the MEAs were inserted into the lumbar dorsal column (i.e., the fasciculus gracilis) to determine somatotopic representations corresponding to tactile stimulation across lower body regions and assess proprioceptive signals with varying hip positions. For stimulations, at the L3 level, we delivered electrical pulses both rostrally, along ascending afferent tracts (dorsal column), and caudally, down descending corticospinal tract. We successfully captured axonal CAPs from the dorsal columns with high spatial precision that corresponded to known dermatomal somatotopy. Proprioceptive changes produced by abduction at the hip resulted in modulation of discharge frequency in the dorsal column axons. We demonstrated that stimulation pulses emitted by a caudally placed electrode could be propagated up the ascending fibers and be intercepted by a rostrally placed electrode array along the same axonal tracts. We also confirmed that electrical pulses can be directed down descending corticospinal tracts resulting in specific activations of lower limb muscles. These findings set a critical groundwork for developing closed-loop, bidirectional SCMI systems capable of sensing and modulating spinal cord activity.</p>","PeriodicalId":13419,"journal":{"name":"IEEE Transactions on Neural Systems and Rehabilitation Engineering","volume":"PP ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144077822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Collaborative AI Dysarthric Speech Recognition System with Data Augmentation using Generative Adversarial Neural Network.","authors":"Yibo He, Kah Phooi Seng, Li Minn Ang","doi":"10.1109/TNSRE.2025.3570383","DOIUrl":"https://doi.org/10.1109/TNSRE.2025.3570383","url":null,"abstract":"<p><p>This paper proposes a novel collaborative dysarthric speech recognition system designed to convert dysarthric speech into non-dysarthric speech to enhance the robustness of automatic speech recognition (ASR) systems fine-tuned for dysarthric speech. The system employs an innovative three-stage data augmentation framework: The first stage collaboratively augments the training dataset by generating static data and high-quality synthetic speech samples using a natural text-to-speech model (Tacotron2). The second stage applies a tempo perturbation technique that simulates the natural variation of speech rhythms by adjusting the playback tempo to improve the model's adaptability to varying speech speeds. The third stage integrates the Inception-ResNet module with a temporal masking strategy using an enhanced CycleGAN-based conversion model to efficiently map conformal and non-conformal phonological features while preserving the overall speech structure and resolving temporal irregularities. Experiments conducted on the UASpeech corpus demonstrate a significant reduction in the word error rate (WER) compared to the baseline approach. Specifically, the three-stage data enhancement process achieves a reduction in the WER for the fine-tuned Wav2Vec2-XLSR and Whisper-Tiny models by 9.81% and 6.56%, respectively, with an average WER of 13.58% for the best performing system. These results highlight the effectiveness of the collaborative framework in improving the accuracy and naturalness of speech recognition for dysarthria, thereby offering individuals with dysarthria a more natural and intelligible communication experience.</p>","PeriodicalId":13419,"journal":{"name":"IEEE Transactions on Neural Systems and Rehabilitation Engineering","volume":"PP ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144077821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Performance of Ankle Exoskeletons on Irregular Terrains: Key Design Principles and Benchmarking Tests.","authors":"L Liguori, G Mariani, J Taborri, I Mileti, D Torricelli, L Mattioli, E Palermo, F Patane, S Rossi","doi":"10.1109/TNSRE.2025.3569959","DOIUrl":"https://doi.org/10.1109/TNSRE.2025.3569959","url":null,"abstract":"<p><p>Exoskeletons offer an advanced solution for assisting and rehabilitating physically impaired people. The mechanical design of these devices can significantly affect the kinematics of the user by restricting limb movements. In this study, we present the mechanical design of two new prototypes of ankle exoskeleton with a different number of degrees-of-freedom (DoF) and different torque transmission method. Specifically, the first prototype (S-RANK) accommodates a single DoF in the sagittal plane, whereas the second prototype (M-RANK) extends the functionality to include ankle inversion/eversion and internal/external rotation. To assess the impact of the mechanical design of the exoskeletons on the kinematics of the lower limb, the two devices were donned on the right leg by two healthy subjects and tested on five different terrains. Human kinematics of the left and right lower limbs were collected using inertial measurement units (IMUs). The study assessed the effects on trend symmetry (TS) between the left and right limb kinematic parameters and used statistical parametric mapping (SPM) to compare joint angle curves with and without each prototype. The findings indicated that both prototypes exerted a notable influence on joint kinematics. The S-RANK resulted in a higher overall difference (OD), particularly at the ankle joint across all terrains except during downhill walking, with the largest deviations observed on softer surfaces. In contrast, M-RANK had a less pronounced effect on ankle kinematics but generally performed worse on the knee and hip joints. In these instances, it led to higher OD when walking on flat and softer surfaces. The two exoskeleton prototypes affected gait symmetry on all terrains, with S-RANK leading to a significant worsening on flat terrain. The findings indicate that while S-RANK offered stability and a less pronounced effect on proximal joint kinematics, M-RANK's additional degrees of freedom provided superior adaptability and maintenance of natural gait patterns.</p>","PeriodicalId":13419,"journal":{"name":"IEEE Transactions on Neural Systems and Rehabilitation Engineering","volume":"PP ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144077824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Visual Disturbances to Avatar Foot Position Increase Step-width Variability in Immersive VR Treadmill Walking.","authors":"Alex van den Berg, Katherine L Poggensee, David Abbink, Laura Marchal-Crespo","doi":"10.1109/TNSRE.2025.3570241","DOIUrl":"https://doi.org/10.1109/TNSRE.2025.3570241","url":null,"abstract":"<p><p>Gait variability, the subtle fluctuations in walking patterns, is crucial for adaptation and motor learning. While existing methods to increase gait variability often rely on force-based perturbations, these can reduce motivation. This study explored if a subtle visual feedback distortion (VFD), applied to a first-person avatar's foot position in an immersive virtual reality environment, could increase gait variability without such a drawback. Twenty healthy adults walked on a treadmill wearing a head-mounted display and motion trackers, performing a stepping task under two conditions: with and without VFD. The VFD introduced a continuously changing, noise-like offset to the displayed foot positions, designed to be minimally noticeable. We quantified gait variability through the standard deviation of step width and step length and collected self-report measures on embodiment, motivation, and simulator sickness. We found that VFD significantly increased step width variability by about 15%, indicating enhanced lateral adaptability. In contrast, step length variability remained unchanged. Participants adjusted their foot placement in the opposite direction of the visual distortion, supporting the idea that proprioceptive recalibration underpinned the observed changes. Notably, this increase in variability occurred without any significant effects on embodiment, motivation, or simulator sickness. These findings suggest that subtle VFD can enhance gait variability-potentially facilitating motor learning and adaptability-while preserving user experience and motivation. Future research should determine whether such VFD-based interventions yield lasting functional improvements and investigate their applicability in rehabilitation contexts, potentially offering a noninvasive, user-friendly approach to promoting healthy gait dynamics.</p>","PeriodicalId":13419,"journal":{"name":"IEEE Transactions on Neural Systems and Rehabilitation Engineering","volume":"PP ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144077825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Unpowered Exoskeleton with a Bionic Multi-segment Foot Structure for Walking Assistance.","authors":"Yueling Lyu, Yiyue Lin, Shaofeng Zhao, Jianrui Wei, Xianyi Zhang","doi":"10.1109/TNSRE.2025.3569835","DOIUrl":"https://doi.org/10.1109/TNSRE.2025.3569835","url":null,"abstract":"<p><p>Lower limb exoskeletons have been designed to assist human walking. However, current unpowered exoskeletons primarily targeted the ankle joint, but neglected the energy storage and recoil within the foot. In this study, we proposed an unpowered foot-ankle exoskeleton with a bionic multi-segment foot structure to mimic energy conservation strategies of natural barefoot walking. An archlike structure was built in the exoskeleton with springs aligning with the medial longitudinal arch and the plantar fascia to store elastic energy in the early and midstance phases and recoil energy in the late stance phase of walking. We found that compared with mass-matched experimental shoes, the exoskeleton reduced the total net metabolic cost of walking by 8.5 ± 3.1% for healthy individuals, and caused a 10.6% reduction in the average activity and a 25.9% reduction in the tissue oxygen saturation index of the soleus. As expected, the exoskeleton did not interfere with the natural motion of the midfoot and ankle joints during walking. The exoskeleton may help reduce energetic penalties by assisting the soleus concentric contraction for propulsion and permitting sufficient intra-foot motion. Our results highlight the importance of utilizing elastic energy storage of intra-foot structures for walking assistance, and imply that implementing a multi-foot structure have a potential to further improve the performance of walking assistance devices.</p>","PeriodicalId":13419,"journal":{"name":"IEEE Transactions on Neural Systems and Rehabilitation Engineering","volume":"PP ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144077820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Grasp-dependent modulations in EEG - EMG coherence are observed in young but not older adults.","authors":"Balasubramanian Eswari, Sivakumar Balasubramanian, Skm Varadhan","doi":"10.1109/TNSRE.2025.3569859","DOIUrl":"https://doi.org/10.1109/TNSRE.2025.3569859","url":null,"abstract":"<p><p>EEG-EMG coherence (Corticomuscular coherence - CMC) reveals the functional connection between the cortical activity and muscle activity during voluntary movements. During voluntary movements the cortical and muscle activity are synchronized in the beta band range. Age-related deteriorations in the central and peripheral system can impair communication between the brain's cortical regions and the muscle activity. This study aim to examine the beta band EEG - EMG coherence in older individuals and compare the results with young adults. Twenty-two-channel EEG and two-channel EMG data were collected from twenty healthy young adults aged 20-30 (26.96±2.68) and fourteen older adults aged 58-72 (62.57±3.58). Participants were instructed to hold a handle gently for five seconds, then lift and hold it for an additional five seconds under fixed and free conditions (with the thumb platform either fixed or sliding). EEG - EMG coherence magnitude was lower in the older group compare to the young group. Furthermore, the magnitude of EEG-EMG coherence of the young group was greater in the fixed condition than the free condition. In contrast, no difference in EEG-EMG coherence magnitude was observed in the older group between the task conditions. In summary, older adults exhibit reduced and consistent EEG - EMG coherence across different motor tasks compared to younger adults, reflecting age-related declines in neural synchrony and motor control efficiency. In contrast, younger individuals exhibit task related modulation in EEG-EMG coherence magnitude. This suggests a fundamental difference in motor control mechanisms between younger and older populations during task performance.</p>","PeriodicalId":13419,"journal":{"name":"IEEE Transactions on Neural Systems and Rehabilitation Engineering","volume":"PP ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144077823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhanced Optogenetic Stimulation of Retinal Ganglion Cells with Assistive Electric Stimulation for Low Optical Power Artificial Vision.","authors":"Hyeonhee Roh, Joonghoon Kang, Hyung-Min Lee, Maesoon Im","doi":"10.1109/TNSRE.2025.3568864","DOIUrl":"https://doi.org/10.1109/TNSRE.2025.3568864","url":null,"abstract":"<p><p>High optical power of optogenetic stimulation may cause phototoxicity during chronic application. To lower the optical power, a hybrid approach which combines optogenetic and electric modalities has been proposed. However, the hybrid stimulation effect has not been well studied in the retina, which would be an ideal target of optogenetic intervention for sight restoration. Here, we investigated the assistive effect of electric pulses while optogenetic stimulation in both wild-type (wt) and retinal degeneration 10 (rd10) mouse retinas. We injected AAV2-CAG-ChR2(H134R)-EGFP into the 4-week-old mouse eyeballs. After > 4 weeks, spiking activities of retinal ganglion cells of ex-vivo retinas were recorded using a cell-attached patch clamping in response to hybrid stimulation: 3 light intensities (i.e., Levels 1, 2, and 3) for optogenetic stimulation and 3 types of assistive electric pulses (i.e., -5 and -10 μA square pulses, and -20 μA increasing ramping current) were tested. Notably, in wt retina, the hybrid stimulation with -10 μA square pulse evoked significantly more spikes compared to the optogenetic-only case, showing average increases of 1.89 ± 2.34, 2.49 ± 1.92, and 2.50 ± 1.61 spikes for the Levels 1, 2 and 3, respectively. For the same conditions, spiking latencies were reduced by 35.27 ± 41.34, 10.62 ± 13.73, and 8.64 ± 15.33 ms. These results demonstrate hybrid stimulation can enhance spiking magnitude and reduce temporal delay. Also, our results indicate assistive electric pulse is more effective for lower power optogenetic stimulation than higher one but the assistive effect was reduced in rd10 retinas. Our study suggests hybrid stimulation holds promise for enhancing chronic applicability of optogenetic approaches for vision restoration by lengthening battery life through the reduced optical power requirement.</p>","PeriodicalId":13419,"journal":{"name":"IEEE Transactions on Neural Systems and Rehabilitation Engineering","volume":"PP ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143963442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Detecting Activities of Daily Living in Egocentric Video to Contextualize Hand Use at Home in Outpatient Neurorehabilitation Settings.","authors":"Adesh Kadambi, Jose Zariffa","doi":"10.1109/TNSRE.2025.3569083","DOIUrl":"https://doi.org/10.1109/TNSRE.2025.3569083","url":null,"abstract":"<p><p>Wearable egocentric cameras and machine learning have the potential to provide clinicians with a more nuanced understanding of patient hand use at home after stroke and spinal cord injury (SCI). However, they require detailed contextual information (i.e., activities and object interactions) to effectively interpret metrics and meaningfully guide therapy planning. We demonstrate that an object-centric approach, focusing on what objects patients interact with rather than how they move, can effectively recognize Activities of Daily Living (ADL) in real-world rehabilitation settings. We evaluated our models on a complex dataset collected in the wild comprising 2261 minutes of egocentric video from 16 participants with impaired hand function. By leveraging pre-trained object detection and hand-object interaction models, our system achieves robust performance across different impairment levels and environments, with our best model achieving a mean weighted F1-score of 0.78 ± 0.12 and maintaining an F1-score over 0.5 for all participants using leave-one-subject-out cross validation. Through qualitative analysis, we observe that this approach generates clinically interpretable information about functional object use while being robust to patient-specific movement variations, making it particularly suitable for rehabilitation contexts with prevalent upper limb impairment.</p>","PeriodicalId":13419,"journal":{"name":"IEEE Transactions on Neural Systems and Rehabilitation Engineering","volume":"PP ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143963207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Learning Developmental Age from 3D Infant Kinetics Using Adaptive Graph Neural Networks.","authors":"Daniel Holmberg, Manu Airaksinen, Viviana Marchi, Andrea Guzzetta, Anna Kivi, Leena Haataja, Sampsa Vanhatalo, Teemu Roos","doi":"10.1109/TNSRE.2025.3568269","DOIUrl":"https://doi.org/10.1109/TNSRE.2025.3568269","url":null,"abstract":"<p><p>Reliable methods for the neurodevelopmental assessment of infants are essential for early detection of problems that may need prompt interventions. Spontaneous motor activity, or 'kinetics', is shown to provide a powerful surrogate measure of upcoming neurodevelopment. However, its assessment is by and large qualitative and subjective, focusing on visually identified, age-specific gestures. In this work, we introduce Kinetic Age (KA), a novel data-driven metric that quantifies neurodevelopmental maturity by predicting an infant's age based on their movement patterns. KA offers an interpretable and generalizable proxy for motor development. Our method leverages 3D video recordings of infants, processed with pose estimation to extract spatio-temporal series of anatomical landmarks, which are released as a new openly available dataset. These data are modeled using adaptive graph convolutional networks (AAGCNs), able to capture the spatio-temporal dependencies in infant movements. We also show that our data-driven approach achieves improvement over traditional machine learning baselines based on manually engineered features.</p>","PeriodicalId":13419,"journal":{"name":"IEEE Transactions on Neural Systems and Rehabilitation Engineering","volume":"PP ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143995431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Context-Informed Incremental Learning Improves Throughput and Reduces Drift in Regression-Based Myoelectric Control.","authors":"Christian Morrell, Evan Campbell, Ethan Eddy, Erik Scheme","doi":"10.1109/TNSRE.2025.3567245","DOIUrl":"https://doi.org/10.1109/TNSRE.2025.3567245","url":null,"abstract":"<p><p>Despite decades of research, commercially available powered myoelectric prostheses continue to use sequential, classification-based control. While regression-based approaches can improve the dexterity offered through simultaneous, independent, and proportional control, current training protocols lack consistency across studies and fail to capture realistic user behaviours, resulting in robustness issues. To address these challenges, this work employs context-informed incremental learning (CIIL) in an unconstrained, velocity-based environment for regression-based myoelectric control. Two new adaptive models, one inspired by previous works (O-CIIL) and one modified to factor in user compliance and behaviours (T-CIIL), were compared with two models trained using traditional screen-guided training. Sixteen participants completed an online Fitts' Law target acquisition task. Both adaptive approaches significantly outperformed (p < 0.05) the non-adaptive models across a variety of metrics. Additionally, T-CIIL outperformed O-CIIL in alleviating drift and action interference, key issues that have plagued existing regressionbased myoelectric control systems. These findings are supported by two novel metrics, namely action interference and simultaneity gain, which show that adding simultaneity often increases instability in the form of undesired and uncontrollable simultaneous motions. These findings demonstrate the viability of CIIL in an unconstrained, velocity-controlled environment for regression-based myoelectric control, and highlight the importance of capturing user behaviours when training regression-based myoelectric control systems. Source code is available on GitHub.</p>","PeriodicalId":13419,"journal":{"name":"IEEE Transactions on Neural Systems and Rehabilitation Engineering","volume":"PP ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143997884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}