Mingzhao Yu,Mallory R Peterson,Kathy Burgoine,Thaddeus Harbaugh,Peter Olupot-Olupot,Melissa Gladstone,Cornelia Hagmann,Frances M Cowan,Andrew Weeks,Sarah U Morton,Ronald Mulondo,Edith Mbabazi-Kabachelor,Steven J Schiff,Vishal Monga
{"title":"CLIF-Net: Intersection-guided Cross-view Fusion Network for Infection Detection from Cranial Ultrasound.","authors":"Mingzhao Yu,Mallory R Peterson,Kathy Burgoine,Thaddeus Harbaugh,Peter Olupot-Olupot,Melissa Gladstone,Cornelia Hagmann,Frances M Cowan,Andrew Weeks,Sarah U Morton,Ronald Mulondo,Edith Mbabazi-Kabachelor,Steven J Schiff,Vishal Monga","doi":"10.1109/tmi.2025.3570316","DOIUrl":"https://doi.org/10.1109/tmi.2025.3570316","url":null,"abstract":"This paper addresses the problem of detecting possible serious bacterial infection (pSBI) of infancy, i.e. a clinical presentation consistent with bacterial sepsis in newborn infants using cranial ultrasound (cUS) images. The captured image set for each patient enables multiview imagery: coronal and sagittal, with geometric overlap. To exploit this geometric relation, we develop a new learning framework, called the intersection-guided Crossview Local- and Image-level Fusion Network (CLIF-Net). Our technique employs two distinct convolutional neural network branches to extract features from coronal and sagittal images with newly developed multi-level fusion blocks. Specifically, we leverage the spatial position of these images to locate the intersecting region. We then identify and enhance the semantic features from this region across multiple levels using cross-attention modules, facilitating the acquisition of mutually beneficial and more representative features from both views. The final enhanced features from the two views are then integrated and projected through the image-level fusion layer, outputting pSBI and non-pSBI class probabilities. We contend that our method of exploiting multi-view cUS images enables a first of its kind, robust 3D representation tailored for pSBI detection. When evaluated on a dataset of 302 cUS scans from Mbale Regional Referral Hospital in Uganda, CLIF-Net demonstrates substantially enhanced performance, surpassing the prevailing state-of-the-art infection detection techniques.","PeriodicalId":13418,"journal":{"name":"IEEE Transactions on Medical Imaging","volume":"39 1","pages":""},"PeriodicalIF":10.6,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144065795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tianqi Chen, Jun Hou, Yinchi Zhou, Huidong Xie, Xiongchao Chen, Qiong Liu, Xueqi Guo, Menghua Xia, James S. Duncan, Chi Liu, Bo Zhou
{"title":"2.5D Multi-view Averaging Diffusion Model for 3D Medical Image Translation: Application to Low-count PET Reconstruction with CT-less Attenuation Correction","authors":"Tianqi Chen, Jun Hou, Yinchi Zhou, Huidong Xie, Xiongchao Chen, Qiong Liu, Xueqi Guo, Menghua Xia, James S. Duncan, Chi Liu, Bo Zhou","doi":"10.1109/tmi.2025.3570342","DOIUrl":"https://doi.org/10.1109/tmi.2025.3570342","url":null,"abstract":"","PeriodicalId":13418,"journal":{"name":"IEEE Transactions on Medical Imaging","volume":"60 1","pages":""},"PeriodicalIF":10.6,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144066159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xiang Zeng,Shengwu Xiong,Jinming Xu,Guangxing Du,Yi Rong
{"title":"Uncertainty Co-estimator for Improving Semi-Supervised Medical Image Segmentation.","authors":"Xiang Zeng,Shengwu Xiong,Jinming Xu,Guangxing Du,Yi Rong","doi":"10.1109/tmi.2025.3570310","DOIUrl":"https://doi.org/10.1109/tmi.2025.3570310","url":null,"abstract":"Recently, combining the strategy of consistency regularization with uncertainty estimation has shown promising performance on semi-supervised medical image segmentation tasks. However, most existing methods estimate the uncertainty solely based on the outputs of a single neural network, which results in imprecise uncertainty estimations and eventually degrades the segmentation performance. In this paper, we propose a novel Uncertainty Co-estimator (UnCo) framework to deal with this problem. Inspired by the co-training technique, UnCo establishes two different mean-teacher modules (i.e., two pairs of teacher and student models), and estimates three types of uncertainty from the multi-source predictions generated by these models. Through combining these uncertainties, their differences will help to filter out incorrect noise in each estimate, thus allowing the final fused uncertainty maps to be more accurate. These resulting maps are then used to enhance a cross-consistency regularization imposed between the two modules. In addition, UnCo also designs an internal consistency regularization within each module, so that the student models can aggregate diverse feature information from both modules, thus promoting the semi-supervised segmentation performance. Finally, an adversarial constraint is introduced to maintain the model diversity. Experimental results on four medical image datasets indicate that UnCo can achieve new state-of-the-art performance on both 2D and 3D semi-supervised segmentation tasks. The source code will be available at https://github.com/z1010x/UnCo.","PeriodicalId":13418,"journal":{"name":"IEEE Transactions on Medical Imaging","volume":"28 1","pages":""},"PeriodicalIF":10.6,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144065789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jordina Aviles Verdera, Antonia Bortolazzi, Sara Neves Silva, Kelly Payette, Kamilah St. Clair, Sarah McElroy, Shaihan Malik, Joseph Hajnal, Raphael Tomi-Tricot, Mary Rutherford, Jana Hutter
{"title":"HERON: High-Efficiency Real-Time mOtion quantification and re-acquisitioN for Fetal diffusion MRI","authors":"Jordina Aviles Verdera, Antonia Bortolazzi, Sara Neves Silva, Kelly Payette, Kamilah St. Clair, Sarah McElroy, Shaihan Malik, Joseph Hajnal, Raphael Tomi-Tricot, Mary Rutherford, Jana Hutter","doi":"10.1109/tmi.2025.3569853","DOIUrl":"https://doi.org/10.1109/tmi.2025.3569853","url":null,"abstract":"","PeriodicalId":13418,"journal":{"name":"IEEE Transactions on Medical Imaging","volume":"122 1","pages":"1-1"},"PeriodicalIF":10.6,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143979398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"SA-Seg: Annotation-Efficient Segmentation for Airway Tree Using Saliency-based Annotation","authors":"Kai Zhou, Nan Chen, Zhang Yi, Xiuyuan Xu","doi":"10.1109/tmi.2025.3568855","DOIUrl":"https://doi.org/10.1109/tmi.2025.3568855","url":null,"abstract":"","PeriodicalId":13418,"journal":{"name":"IEEE Transactions on Medical Imaging","volume":"6 1","pages":""},"PeriodicalIF":10.6,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143939786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zhanqiang Guo, Zimeng Tan, Jianjiang Feng, Jie Zhou
{"title":"VesselDiffusion: 3D Vascular Structure Generation Based on Diffusion Model","authors":"Zhanqiang Guo, Zimeng Tan, Jianjiang Feng, Jie Zhou","doi":"10.1109/tmi.2025.3568602","DOIUrl":"https://doi.org/10.1109/tmi.2025.3568602","url":null,"abstract":"","PeriodicalId":13418,"journal":{"name":"IEEE Transactions on Medical Imaging","volume":"27 1","pages":""},"PeriodicalIF":10.6,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143930937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yuzhu He,Chunfeng Lian,Ruyi Xiao,Fangmao Ju,Chao Zou,Zongben Xu,Jianhua Ma
{"title":"Anatomy-Aware Deep Unrolling for Task-Oriented Acceleration of Multi-Contrast MRI.","authors":"Yuzhu He,Chunfeng Lian,Ruyi Xiao,Fangmao Ju,Chao Zou,Zongben Xu,Jianhua Ma","doi":"10.1109/tmi.2025.3568157","DOIUrl":"https://doi.org/10.1109/tmi.2025.3568157","url":null,"abstract":"Multi-contrast magnetic resonance imaging (MC-MRI) plays a crucial role in clinical practice. However, its performance is hindered by long scanning times and the isolation between image acquisition and downstream clinical diagnoses/treatments. Despite the activated research on accelerated MC-MRI, few existing studies prioritize personalized imaging tailored to individual patient characteristics and clinical needs. That is, the current approach often aims to enhance overall image quality, disregarding the specific pathologies or anatomical regions that are of particular interest to clinicians. To tackle this challenge, we propose an anatomy-aware unrolling-based deep network, dubbed as A2MC-MRI, offering promising interpretability and learning capacity for fast MC-MRI catering to downstream clinical needs. The network is unfolded from the iterative algorithm designed for a task-oriented MC-MRI reconstruction model. Specifically, to enhance concurrent MC-MRI of specific targets of interest (TOIs), the model integrates a learnable group sparsity with an anatomyaware denoising prior. Within the anatomy-aware denoising prior, a segmentation network is involved to provide critical location information for TOI-enhanced denoising. Finally, such an unrolled network is jointly learned with k-space sampling patterns for task-oriented MC-MR reconstruction. Comprehensive evaluations on two public benchmarks as well as an in-house dataset demonstrate that our A2MCMRI led to state-of-the-art performance in MC-MRI reconstruction under high acceleration rates, featuring notable enhancements in TOI imaging quality. The code will be available at https://github.com/ladderlab-xjtu/A2MC-MRI.","PeriodicalId":13418,"journal":{"name":"IEEE Transactions on Medical Imaging","volume":"48 1","pages":""},"PeriodicalIF":10.6,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143926380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}