Immunological communications最新文献_第2页

Clinical significance of immunologic and immunogenetic evaluation in multiple sclerosis. 多发性硬化症免疫及免疫遗传学评价的临床意义。

Immunological communications Pub Date : 1984-01-01 DOI: 10.3109/08820138409048671

P B Jozefczyk, R H Kelly, B S Rabin

引用次数: 5

Some immunochemical properties of pig kidney DOPA decarboxylase. 猪肾多巴脱羧酶的免疫化学性质。

Immunological communications Pub Date : 1984-01-01 DOI: 10.3109/08820138409048672

M A Rosei, G Citro, M D'Erme, A Finazzi-Agrò

引用次数: 0

A modified microcomplement fixation test for antigen or antibody determination in soluble immune complexes, using gel filtration. 一种改良的微补体固定试验，用于测定可溶性免疫复合物中的抗原或抗体，使用凝胶过滤。

Immunological communications Pub Date : 1984-01-01 DOI: 10.3109/08820138409025467

T S Kaufman, H A Riccomi

引用次数: 0

Anamnestic chemiluminescence of murine spleen cells. 小鼠脾细胞的遗忘性化学发光。

Immunological communications Pub Date : 1984-01-01 DOI: 10.3109/08820138409025468

L S Wong, J L Kiel

引用次数: 1

Liver as a tumor-cell-killing organ. 肝脏是杀死肿瘤细胞的器官。

Immunological communications Pub Date : 1984-01-01 DOI: 10.3109/08820138409025451

V Burkart, M Malter, R Süss, E A Friedrich

引用次数: 16

An improved macrophage spreading assay--a simple and effective measure of activation. 一种改进的巨噬细胞扩散试验——一种简单有效的激活测量方法。

Immunological communications Pub Date : 1984-01-01 DOI: 10.3109/08820138409025464

K Donaldson, R E Bolton, D Brown, A Douglas

引用次数: 23

Specificity of antigen induced helper factor for antibody synthesis in vitro and its relation to lymphocytes interaction. 抗原诱导辅助因子体外合成抗体的特异性及其与淋巴细胞相互作用的关系。

Immunological communications Pub Date : 1984-01-01 DOI: 10.3109/08820138409048669

N Khansari, H H Fudenberg

{"title":"Specificity of antigen induced helper factor for antibody synthesis in vitro and its relation to lymphocytes interaction.","authors":"N Khansari, H H Fudenberg","doi":"10.3109/08820138409048669","DOIUrl":"https://doi.org/10.3109/08820138409048669","url":null,"abstract":"Human peripheral blood B-cells can be stimulated with PWM and antigen to produce specific antibody in vitro. This stimulation depends on the presence of T-cells and antigen. T cells, however, can be replaced by a soluble factor derived from a 48-hr culture of T-cells with either PWM and/or antigen. The helper factor, in the absence of antigen, acts as a polyclonal activator causing minimal proliferation of B-cells. When antigen is present, production of specific antibody is not dependent on the source of helper factor. Removal of monocytes abolished synthesis of both Ig and specific antibody although antigen and/or helper factor were present. While production of total IgG required autologous monocytes, the origin of the helper factor was not crucial. Production of specific antibody required that both monocytes and helper factor be derived from the same donor; therefore it seems that cooperation of B-, T-cells and monocytes for production of specific antibody is probably Ia restricted. In contrast, for production of polyclonal Ig (in the absence of antigen), cooperation of B-cells and monocytes with T-cells is not.","PeriodicalId":13417,"journal":{"name":"Immunological communications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08820138409048669","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17300801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Wheat germ agglutinin decreases expression of the T8 antigen on human peripheral mononuclear cells. 小麦胚芽凝集素降低T8抗原在人外周单核细胞上的表达。

Immunological communications Pub Date : 1984-01-01 DOI: 10.3109/08820138409061303

D H Boldt, S A Dorsey

{"title":"Wheat germ agglutinin decreases expression of the T8 antigen on human peripheral mononuclear cells.","authors":"D H Boldt, S A Dorsey","doi":"10.3109/08820138409061303","DOIUrl":"https://doi.org/10.3109/08820138409061303","url":null,"abstract":"We examined dynamics of expression of the human T-suppressor specific antigen, T8, following interaction of peripheral lymphocytes with wheat germ agglutinin (WGA). Cells were incubated at 37 degrees C with or without WGA (15 micrograms/ml) for 18 hrs, washed sequentially with N-acetylglucosamine (to remove bound WGA) and plain medium, then analyzed by flow cytometry for binding of lectins and monoclonal antibodies OKT8(T-suppressor specific) and OKT3 (pan-T specific). WGA pretreatment induced an overall 65% reduction in WGA binding and concomitant 30% reduction in percentage of T8+ cells. Furthermore, residual T8+ cells showed 50% reduction in T8 expression. Taking into account reductions in both percentages of T8+ cells and also antigen densities, WGA reduced T8 expression by greater than 60% overall. By contrast, binding of OKT3 and the lectins, concanavalin A (con A) and Ricinus communis agglutinin (RCA-I), was unaffected by WGA. The decreased T8 expression could not be explained by residual cell bound WGA and was fully reversible within 48 hours of removal of cells from WGA-containing medium. Therefore, WGA caused downregulation of T8 antigen expression. The effect of WGA was time- and concentration-dependent. Downregulation did not occur at 4 degrees C nor in the presence of azide, thereby demonstrating a requirement for cellular metabolism. The data suggest that WGA may bind to the T8 antigen, and they provide the possibility that similar downregulation of T8 by WGA may underlie certain of the in vitro immunoregulatory effects of this lectin.","PeriodicalId":13417,"journal":{"name":"Immunological communications","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08820138409061303","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17306180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Circulating immune complexes in systemic scleroderma. 系统性硬皮病的循环免疫复合物。

Immunological communications Pub Date : 1984-01-01 DOI: 10.3109/08820138409033889

Z Swierczynska, H Rdultowska, M Blaszczyk, S Jablonska, S Luft

引用次数: 3

Interleukin 2-dependent T cell line acquires responsiveness to phorbol myristate acetate and lipopolysaccharide in the course of long-term culture. 白细胞介素2依赖性T细胞在长期培养过程中获得对肉豆蔻酸酯和脂多糖的反应性。

Immunological communications Pub Date : 1984-01-01 DOI: 10.3109/08820138409033894

N Mukaida, T Kasahara, K Shioiri-Nakano, T Kawai

引用次数: 8