Indo. J. Chem. Res.最新文献_第5页

Utilization of Aur-Aur Grass as A Natural Hand Sanitizer in Order To Prevent The Spread of The Covid-19 Virus 利用乌拉尔草作为天然洗手液防止新冠病毒的传播

Indo. J. Chem. Res. Pub Date : 2022-01-31 DOI: 10.30598//ijcr.2022.9-sap

Adilla Lina Putri Amutya, Alfian Zilham Rifa'i, Yogi Prasetiyo, Arum Sari, L. H. Saputri

{"title":"Utilization of Aur-Aur Grass as A Natural Hand Sanitizer in Order To Prevent The Spread of The Covid-19 Virus","authors":"Adilla Lina Putri Amutya, Alfian Zilham Rifa'i, Yogi Prasetiyo, Arum Sari, L. H. Saputri","doi":"10.30598//ijcr.2022.9-sap","DOIUrl":"https://doi.org/10.30598//ijcr.2022.9-sap","url":null,"abstract":"Indonesia is currently amid a Covid-19 virus pandemic. One of the efforts that can be done to prevent the spread of the Covid-19 virus is to wash your hands with soap, or you can use a hand sanitizer. However, hand sanitizers are mostly made of chemicals, many people feel side effects including dry skin, dermatitis, and irritation. This research aims to make hand sanitizer products made from natural ingredients, namely from extracts of aur-aur grass (Commelina diffusa Burm F.). Phytochemical tests showed that aur-aur grass contained 5,188.73 ppm flavonoid compounds, 8,673.60 ppm total phenol (tannin), and 466.30 ppm alkaloids. The manufacture of hand sanitizers was carried out in four variations with each sample having aur-aur extract levels of 5%, 10%, 15%, and 20%. Of the existing hand sanitizer products, all of them have a pH of ±5 and get good responses from satisfaction values above 80%. Hand sanitizer products also can inhibit bacterial growth. The increase in extract levels in the hand sanitizer is directly proportional to the ability to inhibit bacteria, as shown by sample D which has an average inhibition zone of 9.77 mm. ","PeriodicalId":13392,"journal":{"name":"Indo. J. Chem. Res.","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85946268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antibacterial Activity of Pineapple Peel (Ananas comosus) Eco-enzyme Against Acne Bacterias (Staphylococcus aureus and Prapionibacterium acnes) 菠萝皮生态酶对痤疮细菌(金黄色葡萄球菌和痤疮芽孢杆菌)的抑菌活性

Indo. J. Chem. Res. Pub Date : 2022-01-31 DOI: 10.30598//ijcr.2022.9-nin

A. Ramadani, Rizkya Karima, R. Ningrum

{"title":"Antibacterial Activity of Pineapple Peel (Ananas comosus) Eco-enzyme Against Acne Bacterias (Staphylococcus aureus and Prapionibacterium acnes)","authors":"A. Ramadani, Rizkya Karima, R. Ningrum","doi":"10.30598//ijcr.2022.9-nin","DOIUrl":"https://doi.org/10.30598//ijcr.2022.9-nin","url":null,"abstract":"Acne (acne vulgaris) is a skin disease caused by infection or inflammation of the pilosebaceous unit. Staphylococcus aureus and Prapionibacterium acnes was the main actor in the infection. Eco-enzyme that is made from pineapple peel has been stated that have inhibitory activity against gram-positive and negative bacteria, also applied as home industry soap. This study objective as scientific support that Eco-enzyme phytochemical compounds had the antibacterial activity to the acne bacteria. Eco-enzyme was composed of pineapple peel, brown sugar, and water with the ratio of 3:1:10 for 3 months fermentation time. Eco-enzyme was screened of its phytochemical compound and antibacterial activity against S.aureus and P.acnes by dilution with various concentrations (1.5625%, 3, 125%, 6.25%, 12.5%, 25%, and 50% v/v) and various control. The minimum inhibition concentration (MIC) was then tested by diffusion method to determine the inhibition zone with 3 replication using the higher concentration (50%, 75%, 100% v/v). The result showed that eco-enzyme has a clear yellow colour, contains tannin and saponin, MIC of S.aureus and P.acnes bacteria is 50%. The dilution test of eco-enzyme gives the most effective concentration to inhibit S.aureus at eco-enzyme 100% (v/v), contrasted to P. acnes which didn’t show the best inhibition concentration.","PeriodicalId":13392,"journal":{"name":"Indo. J. Chem. Res.","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77310195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

Sterol Constituents of Sea Fan (Gorgonia mariae) as Potential Candidates of MPro Protein SARS-CoV-2 Inhibitor: in silico Study 海扇甾醇成分作为MPro蛋白抑制SARS-CoV-2的潜在候选物的硅研究

Indo. J. Chem. Res. Pub Date : 2022-01-31 DOI: 10.30598//ijcr.2022.9-kel

Faruk Jayanto Kelutur

{"title":"Sterol Constituents of Sea Fan (Gorgonia mariae) as Potential Candidates of MPro Protein SARS-CoV-2 Inhibitor: in silico Study","authors":"Faruk Jayanto Kelutur","doi":"10.30598//ijcr.2022.9-kel","DOIUrl":"https://doi.org/10.30598//ijcr.2022.9-kel","url":null,"abstract":"Ethnobotanically, sea fan was a group of gorgonian coral that have used the Maluku people as medicinal ingredients with secondary metabolites containing sterols, terpenoids, and alkaloids that have anti-inflammatory, anti-viral, anti-cancer, analgesic, gastroprotective, anti-bacterial, anti-cancer, and anti-fouling agents. However, the effectiveness of sterols as anti-viral SARS-CoV-2 has not been reported, so research was needed. The initial stage of targeting (SwissTargetPrediction), binding affinity (Autodock Tools 4.2), and amino acid interactions (Discovery Studio 2016 Client®). The route of administration, pharmacokinetic properties, and acute oral toxicity (LD50) were predicted by Lipinski's rule of five, pre-ADMET, and ProTox-II. The results of target class obtained probability of 10.6% (4,24-dimethyl cholesta-7,22-dien-3ß-ol and 4,24-dimethyl-22-dehydro-cholestanol) and 11, 8% (dinosterol). Binding affinity (ΔG, kcal/mol and Ki, nM) potentially 4,24-dimethyl cholesta-7,22-dien-3ß-ol (-9.90; 55.13) > dinosterol (-9.77; 68.66) > 4,24-dimethyl-22-dehydro-cholestanol (-9.48; 113.33), respectively with the crucial amino acid, Asp187. The test compound has a log P value > 5, so solubility must be considered. Pre-ADMET showed an excellent disposition as a drug and was not mutagenic and carcinogenic. However, the distribution of plasma proteins and the dose of LD50 need to be considered. Thus, sea fan sterols have potential as MPro protein inhibitors.","PeriodicalId":13392,"journal":{"name":"Indo. J. Chem. Res.","volume":"342 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79554260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Emulsion Polymers of Carboxymethyl Cellulose and Methyl Methacrylate with Sodium Dodecyl Sulfate Surfactant as Soil Stabilizer 羧甲基纤维素和甲基丙烯酸甲酯乳液聚合物与十二烷基硫酸钠表面活性剂作土壤稳定剂

Indo. J. Chem. Res. Pub Date : 2022-01-30 DOI: 10.30598//ijcr.2022.9-abi

A. Z. Abidin, R. B. E. T. Nuriman, N. A. Pradipto, Ridwan P. Putra

{"title":"Emulsion Polymers of Carboxymethyl Cellulose and Methyl Methacrylate with Sodium Dodecyl Sulfate Surfactant as Soil Stabilizer","authors":"A. Z. Abidin, R. B. E. T. Nuriman, N. A. Pradipto, Ridwan P. Putra","doi":"10.30598//ijcr.2022.9-abi","DOIUrl":"https://doi.org/10.30598//ijcr.2022.9-abi","url":null,"abstract":"Polymer-based materials have gained considerable attention in the road construction sector due to their ability to improve the mechanical strength and durability of soil. In this study, carboxymethyl cellulose-methyl methacrylate (CMC-MMA) emulsion polymers were prepared from different MMA to CMC mass ratios with sodium dodecyl sulfate surfactant. The synthesized materials were homogeneously mixed with laterite soil, and their unconfined compressive strengths were measured using dry and wet methods on a universal testing machine. The results indicated that the polymers were obtained in high yields with optimum solids content. Characterization using Fourier transform infrared confirmed the homopolymerization probability of monomers in the materials with increased MMA fractions. In addition, the viscosity of the graft-copolymers measured at room temperature was in the range of 1.2-3.2 cP. The polymer-stabilized soils exhibited maximum unconfined compressive strengths of 564 and 162 psi, respectively, obtained from the dry and wet methods. In general, the rise of MMA fraction in the treated soils enhanced the compressive strength of the soil, with a slight increase in soil pH. This study unfolds the potential of cellulose-based materials that can be implemented in soil reinforcement technology.","PeriodicalId":13392,"journal":{"name":"Indo. J. Chem. Res.","volume":"414 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76325899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Molecular Docking Study of Chalcone Derivatives as Potential Inhibitors of SARS-CoV-2 Main Protease 查尔酮衍生物作为SARS-CoV-2主要蛋白酶抑制剂的分子对接研究

Indo. J. Chem. Res. Pub Date : 2022-01-29 DOI: 10.30598//ijcr.2022.9-fit

Adita Silvia Fitriana, Sri Royani

引用次数: 1

The Ouw Natural Clay Impregnation Using Titanium Dioxide as a Rhodamine B Dyestuff Degrader 二氧化钛作为罗丹明B染料降解剂的天然粘土浸渍研究

Indo. J. Chem. Res. Pub Date : 2021-12-01 DOI: 10.30598//ijcr.2022.9-cat

C. Bijang, M. Nurdin, J. Latupeirissa, Thamrin Aziz, Firda Talapessy

引用次数: 1

Morphological Observation, Identification and Isolation of Tropical Marine Microalgae from Ambon Bay, Maluku 马鲁古安汶湾热带海洋微藻的形态观察、鉴定与分离

Indo. J. Chem. Res. Pub Date : 2021-11-29 DOI: 10.30598//ijcr.2022.9-ivo

Ivonne Telussa, N. Hattu, Arielno Sahalessy

{"title":"Morphological Observation, Identification and Isolation of Tropical Marine Microalgae from Ambon Bay, Maluku","authors":"Ivonne Telussa, N. Hattu, Arielno Sahalessy","doi":"10.30598//ijcr.2022.9-ivo","DOIUrl":"https://doi.org/10.30598//ijcr.2022.9-ivo","url":null,"abstract":"Microalgae are photosynthetic microorganisms that are widely distributed in waters. They have the potential as an alternative source of pigments, lipids, proteins, and carbohydrates. In this study, identification and isolation of single-cell microalgae from Ambon Bay were carried out by serial dilution method and inoculation of the culture by appearance/spread on the surface of the solidified agar medium. The results showed that the waters of Ambon Bay have physical parameters such as temperature, pH, salinity, and TDS, which are still within the threshold specified in the seawater quality standard for biota. The water conditions at the 10 sampling locations had different salinity, pH, temperature, and TDS. This condition affects the distribution of microalgae in the waters in Ambon Bay. The image from light microscopy shows that there are 27 species of microalgae scattered in the waters of Ambon Bay, which belong to the classes Chlorophyceae, Flagilariophyceae, Bacillariophyceae (diatoms), Coscinodiscophyceae, and Dinophyceae. Microalgae isolation obtained five species (single-cell) including four species from the class Bacillariophyta (Navicula sp, Nitzschia sp, Cyclotella sp) and one species from the class Chlorophyta (Chlorella sp).","PeriodicalId":13392,"journal":{"name":"Indo. J. Chem. Res.","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87836621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Determination of Surface Acidity on The Natural and Synthetic Montmorillonite Clays by Titration Method 用滴定法测定天然和合成蒙脱土的表面酸度

Indo. J. Chem. Res. Pub Date : 2021-10-03 DOI: 10.30598//ijcr.2020.9-ser

S. J. Sekewael

引用次数: 0

Development of Differential Pulse Anodic Stripping Voltammetry Technique for Cadmium(II) Detection and Its Application in Water Spinach 差分脉冲阳极溶出伏安法检测菠菜中镉的研究进展及应用

Indo. J. Chem. Res. Pub Date : 2021-09-30 DOI: 10.30598//ijcr.2020.9-riz

B. R. Putra, Manggar Arum Aristri, E. Rohaeti, W. Wahyuni

{"title":"Development of Differential Pulse Anodic Stripping Voltammetry Technique for Cadmium(II) Detection and Its Application in Water Spinach","authors":"B. R. Putra, Manggar Arum Aristri, E. Rohaeti, W. Wahyuni","doi":"10.30598//ijcr.2020.9-riz","DOIUrl":"https://doi.org/10.30598//ijcr.2020.9-riz","url":null,"abstract":"Cadmium is a toxic pollutant that is harmful to the environment and humans. The purpose of this research was to develop a method for cadmium(II) detection using differential pulse anodic stripping voltammetry (DPASV) using a glassy carbon electrode. The developed method was then applied for cadmium detection in the vegetable samples which is water spinach. The developed method was optimized in several parameters such as potential window, deposition potential, deposition time, and scan rate. The developed method for cadmium(II) detection was also investigated in its analytical performance includes linearity, precision, detection limit, and quantitation limit. The optimum conditions for cadmium(II) detection in 0.1 M KCl using DPASV technique obtained such as potential window from -1200 to -100 mV, deposition potential of -1100 mV (vs Ag/AgCl), and deposition time of 360 s. It was obtained good linearity for cadmium(II) detection using the DPASV technique with an R2 of 0.996. The precision was expressed as %SBR with 0.66%. The detection and quantitation limits for cadmium(II) detection were 0.4206 µM~0.0771 ppm and 0.5525 µM~0.1013 ppm, respectively. The developed method was then applied for cadmium(II) measurement in the water spinach sample and the obtained cadmium(II) concentration in water spinach was 0.2399 mg/Kg.","PeriodicalId":13392,"journal":{"name":"Indo. J. Chem. Res.","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90268242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Bioaccumulated Mercury by Several Types of Plants in Ex-Traditional Gold Processing Area, Gogorea Village, Buru Island 布鲁岛果戈里村传统黄金加工区几种植物的生物积累汞

Indo. J. Chem. Res. Pub Date : 2021-09-30 DOI: 10.30598//ijcr.2020.9-abr

Abraham Mariwy, Julita B. Manuhutu, D. Frans

{"title":"Bioaccumulated Mercury by Several Types of Plants in Ex-Traditional Gold Processing Area, Gogorea Village, Buru Island","authors":"Abraham Mariwy, Julita B. Manuhutu, D. Frans","doi":"10.30598//ijcr.2020.9-abr","DOIUrl":"https://doi.org/10.30598//ijcr.2020.9-abr","url":null,"abstract":"This study examines the accumulation of metallic mercury by several types of plants in the traditional gold processing area in the village of Gogore, Buru district. The plants that were sampled in this study were guava, lempuyang gajah, and harendong bulu. These three plant species were chosen because they dominate the vegetation in the gold processing area. The analysis results showed that the lempuyang gajah was the plant that accumulated the highest mercury metal, namely in the roots of 16.79 ppm and the leaves of 15.03 ppm. Guava plants accumulated metal mercury in the roots and leaves of 11.73 ppm and 9.90 ppm, respectively. Meanwhile, harendong plants accumulated mercury in the roots and leaves of 2.59 ppm and 10.39 ppm, respectively. The BCF values of guava, lempuyang gajah, and harendong bulu plants were 1.58, 0.41, and 0.39, respectively. Meanwhile, the TF values of the three plants were 0.84, 0.89, and 4.01, respectively. From these results, it can be concluded that the three plants can accumulate mercury in high enough concentrations, so these three types of plants are categorized as hyper tolerant plants and accumulators.","PeriodicalId":13392,"journal":{"name":"Indo. J. Chem. Res.","volume":"95 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80380751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5