IJAAM (Indonesian Journal of Anti-Aging Medicine)最新文献

{"title":"Comparison of the Effectiveness of the Chemosurgery and Cryosurgery for the Treatment of Patients with Condyloma Acuminatum at Dr. Moewardi Hospital, Surakarta","authors":"P. Mawardi, Bobby Febrianto, Danu Yuliarto","doi":"10.26911/theijmed.2021.06.03.06","DOIUrl":"https://doi.org/10.26911/theijmed.2021.06.03.06","url":null,"abstract":"Background: Condyloma acuminatum (CA) is one of the most common sexually transmitted infections. Several therapeutic modalities that can be used are chemosurgery with trichloroacetic acid and cryosurgery with liquid nitrogen. Recurrence in CA often occurs, so selecting the right therapeutic modality and eliminating the lesion also prevents recurrence. This study aimed to compare the effectiveness of chemosurgery and cryosurgery therapy in patients with CA who are treated at Dr. Moewardi Hospital, Surakarta. Subjects and Method: A retrospective cross-sectional study was conducted at the Dermatology and Venereology Polyclinic, Dr. Moewardi Hospital, Surakarta, from January 1, 2018, to December 31, 2020. The study subjects were 78 patients diagnosed with CA based on ICD-10 criteria, while chemosurgery and cryosurgery procedures were based on ICD-9. The dependent variable was healing time in weeks. The independent variables were chemosurgery and cryosurgery therapy. The data came from the patient's medical record. Data were analyzed using an independent t-test. Results: Based on univariate analysis, most patients were male (67.9%), and the age group was 20-29 years (51.28%). Most of the CA patients work as private employees (46.15%). The most sexual orientation was heterosexual (53.8%), the most common site of lesions was genital (47.4%), and 52.6% were coinfected with HIV. Most CA patients received chemosurgery (70.5%). Bivariate analysis showed that chemosurgery therapy provided faster clinical improvement (Mean= 23.34; SD= 26.45) than cryosurgery therapy (Mean= 28.69; SD= 19.84), and the difference was statistically significant (p= 0.037). Conclusion: Treatment of CA using chemosurgery provides clinical improvement faster than cryosurgery, so that faster treatment time can reduce treatment costs and improve the patient's quality of life. Keywords: chemosurgery, cryosurgery, HPV, condyloma acuminatum Correspondence: Prasetyadi Mawardi. Department of Dermatology and Venereology, Faculty of Medicine of Universitas Sebelas Maret/ Dr. Moewardi Hospital, Surakarta, Central Java, Indonesia. Email: prasetyadimawardi@gmail.com/ prasetyadi_m@staff.uns.ac.id. Mobile: +6281229750211. Indonesian Journal of Medicine (2021), 06(03): 290-297 https://doi.­org/10.26911/the­ijmed.­2021.06.03.06","PeriodicalId":13354,"journal":{"name":"IJAAM (Indonesian Journal of Anti-Aging Medicine)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79394858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effectiveness of Hypnotherapy in Reducing Pain in Patients with Cervical Cancer","authors":"Hanung Prasetya, H. N. Kusumawati, Wardiyatmi Wardiyatmi","doi":"10.26911/theijmed.2021.06.02.04","DOIUrl":"https://doi.org/10.26911/theijmed.2021.06.02.04","url":null,"abstract":"","PeriodicalId":13354,"journal":{"name":"IJAAM (Indonesian Journal of Anti-Aging Medicine)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74424498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Meta-Analysis of Re-perfusion Injury and Ischaemic Conditioning in Limb Surgery","authors":"Pamudji Utomo, Mochamadsyah Beizar Yudhistira","doi":"10.26911/theijmed.2021.06.03.04","DOIUrl":"https://doi.org/10.26911/theijmed.2021.06.03.04","url":null,"abstract":"Background: Pneumatic tourniquet commonly used for orthopedic surgery is associated with morbidity related to ischemia-reperfusion injury. Ischaemia conditioning (IC) had shown beneficial effects to attenuate these outcomes. This study aimed to systematically review the evidence of IC effect on outcomes of the patient undergoing orthopedic surgery. Subjects and Method: This was a systematic review and Meta-Analysis conducted through the online database search from PubMed, Central, Clinicaltrials.gov, and Scopus with topics related to IC and all possible orthopedic surgical interventions. Articles were searched with Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) protocols used keywords \"Ischemic conditioning,\" \"Reperfusion injury,\" \"Orthopaedic surgery.\" The data were extracted from the eligible study within inclusion and exclusion criteria. Two independent reviewers collected the study characteristics. Each study was examined for the risk of bias. The pooled data were analyzed using RevMan 5.3 in Standardized Mean Difference (SMD) as a summary measure with 95% Confidence Interval (CI). Results: Out of 12 eligible studies collected for qualitative analysis, eight studies with the same outcomes were analyzed for quantitative analysis. A random-effect model was used for analysis with high heterogeneity. The pooled SMD data for IC compared to control for postoperative pain were -0.50 (95% CI= -0.95 to 0.06; p<0.001). Outcome measures for hemodynamic stability, systemic inflammation, and end-organ injury were pooled with MD= 4.81 (95% CI= 3.19 to 6.44); SMD= -1.33 (95% CI= -2.06 to -0.60); SMD= 0.15 (95% CI= -0.14 to 0.71); respectively. Conclusion: Ischaemic conditioning significantly reduces postoperative pain, inflammation response and maintains hemodynamic stability. A better study design with a higher population number is needed for further study.","PeriodicalId":13354,"journal":{"name":"IJAAM (Indonesian Journal of Anti-Aging Medicine)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84919227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Relationship between Tumor Size and Carcinoembryonic Antigen (CEA) Levels in Stage IV Colorectal Adenocarcinoma Patients at Dr. Moewardi Hospital, Indonesia","authors":"Rakhmawati Susetyaning Eri, Sulistyani Kusumaningrum, W. Widiastuti, Hari Wujoso, I. B. P. Adnyana, Prasetyo Sarwono Putro","doi":"10.26911/theijmed.2021.06.03.05","DOIUrl":"https://doi.org/10.26911/theijmed.2021.06.03.05","url":null,"abstract":"","PeriodicalId":13354,"journal":{"name":"IJAAM (Indonesian Journal of Anti-Aging Medicine)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87349933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Meta-Analysis of the Effectiveness of Using Antiplatelet Drugs Uptake in Decreasing Mortality in COVID-19 Patients","authors":"Happy Nurhayati, Eti Poncorini Pamungkasari, Bhisma Murti","doi":"10.26911/theijmed.2021.06.03.09","DOIUrl":"https://doi.org/10.26911/theijmed.2021.06.03.09","url":null,"abstract":"Background: Viscoelastic coagulation testing in COVID-19 patients often found elevated concentrations of D-dimer and fibrinogen. Thrombotic complications can be in the form of Venous Thromboembolism (VTE), where this thrombotic disease is one of the factors associated with increased mortality of COVID-19 patients. This study aims to analyze the effectiveness of antiplatelet drugs in reducing mortality in COVID-19 patients. Subjects and Method: This is a meta-analysis study using PRISMA flowchart guidelines. The article search process was carried out between 2020-2021 using PubMed, Science Direct, Google Scholar, and Scopus databases. The article search was carried out by considering the eligibility criteria defined in the PICO model. Population= COVID-19 patients, Intervention= using antiplatelet drugs, Comparison= not using anticoagulant drugs, Outcome= mortality. The keywords used were \"antiplatelet\" AND \"mortality\" AND \"COVID-19\". The inclusion criteria used were English full-text cohort papers and the relationship measure used as the adjusted odds ratio (aOR). Based on the database, 9 articles fulfilled the inclusion criteria. The analysis was carried out using RevMan 5.3 software.","PeriodicalId":13354,"journal":{"name":"IJAAM (Indonesian Journal of Anti-Aging Medicine)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81821119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of the Use of Cervical Collar on the Reduction of Neck Pain: Meta-Analysis","authors":"Hisyam Syafi’ie, Hanung Prasetya, Bhisma Murti","doi":"10.26911/theijmed.2021.06.01.12","DOIUrl":"https://doi.org/10.26911/theijmed.2021.06.01.12","url":null,"abstract":"Background: Neck pain is the fourth leading cause of disability, with an annual prevalence rate exceeding 30%. Nearly 50% of individuals will continue to experience pain or it often occurs to some degree. This study aimed to analyze the magnitude of the effect of using a cervical collar on reducing the degree of pain in neck pain patients compared to manual therapy (exercises). Subjects and Method: This research is a systematic review and meta-analysis carried out by following the PRISM diagram flow. The process of searching for articles through a journal database that includes: PubMed, Google Scholar and Science Direct by selecting articles published in 2000-2020. The keywords used include: “cervical collar” OR “neck collar” OR “soft collar” OR “hard collar” AND “neck pain” AND “cervical pain” AND “cervical radiculopathy” AND “cervical syndrome” AND “randomized controlled trial”. The inclusion criteria were full paper articles with a randomized controlled trial study design, articles using English and Indonesian, and bivariate analysis with adjusted odds ratio. Articles that meet the requirements are analyzed using the Revman 5.3 application. Results: A total of 6 articles were reviewed in this study with a randomized controlled trial study design. Meta-analysis of 6 randomized controlled trial (RCT) studies showed that there was no difference in effectiveness in using cervical collars compared to manual therapy (exercises) in reducing neck pain (ES = 0.04; 95% CI -0.31 to 0.39; p = 0.083). Conclusion: This meta-analysis concluded that there was no difference in effectiveness between the use of cervical collars and manual therapy (exercises) in reducing the degree of pain in neck pain.","PeriodicalId":13354,"journal":{"name":"IJAAM (Indonesian Journal of Anti-Aging Medicine)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85883093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Meta-Analysis of the Role of Varenicline in Smoking Cessation","authors":"M. Lafif, Bhisma Murti, Hanung Prasetya","doi":"10.26911/theijmed.2021.06.04.01","DOIUrl":"https://doi.org/10.26911/theijmed.2021.06.04.01","url":null,"abstract":"","PeriodicalId":13354,"journal":{"name":"IJAAM (Indonesian Journal of Anti-Aging Medicine)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90553495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Agreement of Immunoglobulin Gamma Release Assay (IGRA)/ T-SPOT Tuberculosis and Tuberculin Skin Test to Detect Latent TB Infection in Diabetes Mellitus Patients","authors":"Reviono Reviono, Y. Sutanto, Harsini Harsini, L. Saptawati, M. Marwoto, B. Suryawati, Dhani Redhono, Pribadi M Sebayang","doi":"10.26911/theijmed.2021.06.03.07","DOIUrl":"https://doi.org/10.26911/theijmed.2021.06.03.07","url":null,"abstract":"","PeriodicalId":13354,"journal":{"name":"IJAAM (Indonesian Journal of Anti-Aging Medicine)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75134351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Meta-Analysis: Effects of Obesity and Family History of Diabetes Mellitus on the Risk of Gestational Diabetes Mellitus","authors":"Galuh Sitorukmi, Yulia Lanti Retno Dewi, Bhisma Murti","doi":"10.26911/theijmed.2021.06.01.01","DOIUrl":"https://doi.org/10.26911/theijmed.2021.06.01.01","url":null,"abstract":"Background: Gestational diabetes mellitus is a serious complication of pregnancy, this is due to impaired carbohydrate tolerance which results in increased blood sugar levels and was first noticed during pregnancy. Gestational diabetes mellitus is a global problem in terms of its incidence and impact. Studies suggest that obesity and a family history of diabetes mellitus are important risk factors for gestational diabetes mellitus. This study aimed to analyze the influence of obesity and family history of diabetes mellitus on the incidence of gestational diabetes mellitus by meta-analysis. Subjects and Method: This was a systematic review and meta-analysis carried out by following the PRISMA flow diagram. The electronic database for article searches is as follows: PubMed, Science Direct, Springer Link, Scopus, and Google Scholar. The search for articles was carried out on articles published from 2010 to 2020. The keywords used were \"gestational diabetes mellitus AND obesity\", \"gestational diabetes mellitus AND family history. The inclusion criteria were full text articles, used English, cross-sectional study design, and results reported in adjusted odds ratio (aOR). P= Pregnant mother. I= Obesity and family history of diabetes mellitus. C= No obesity and no family history of diabetes mellitus. O= gestational diabetes mellitus. Articles that meet the requirements are analyzed using the Revman 5.3. Results: Nine articles were reviewed in this study with a total of 11,657 subjects. The results of the meta-analysis showed that obesity increased the risk of gestational diabetes mellitus 1.81 times compared with non-obese (aOR= 1.81; 95% CI= 1.53 to 2.15; p <0.001). Having a family history of diabetes mellitus increased the risk of gestational diabetes mellitus 2.08 times compared with those without a family history of diabetes mellitus (aOR= 2.08; 95% CI= 1.34 to 3.22; p <0.001). Conclusion: Obesity and a family history of diabetes mellitus increase the risk of gestational diabetes mellitus.","PeriodicalId":13354,"journal":{"name":"IJAAM (Indonesian Journal of Anti-Aging Medicine)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85425408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effects of Ethanol Extract, Chayote (Sechium Edule (Jacq.) Swartz) Fraction and Juice on the High-density Lipoprotein Level in Male White Mice","authors":"Jekson Martiar Siahaan, Endy Juli Anto, Tengku Muhammad Fauzi","doi":"10.26911/theijmed.2021.06.02.03","DOIUrl":"https://doi.org/10.26911/theijmed.2021.06.02.03","url":null,"abstract":"","PeriodicalId":13354,"journal":{"name":"IJAAM (Indonesian Journal of Anti-Aging Medicine)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73547124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}