{"title":"Prevalence and factors associated with high risk for obstructive sleep apnea in schizophrenia spectrum disorder patients on long-term clozapine.","authors":"Rika Rijal, Sandeep Grover, Subho Chakrabarti, Swapnajeet Sahoo","doi":"10.4103/indianjpsychiatry.indianjpsychiatry_544_24","DOIUrl":"10.4103/indianjpsychiatry.indianjpsychiatry_544_24","url":null,"abstract":"<p><strong>Aim: </strong>This study aimed to evaluate the prevalence of obstructive sleep apnea (OSA) and its correlates among schizophrenia spectrum disorder patients receiving clozapine.</p><p><strong>Methods: </strong>For this, 200 schizophrenia spectrum disorder patients receiving clozapine for at least one year were assessed on the Berlin Sleep Questionnaire for OSA.</p><p><strong>Results: </strong>Around one-sixth of the study sample (16.5%) had a high risk for OSA at a body mass index (BMI) cut-off of 30 kg/m<sup>2</sup>. When a BMI cut-off of 25 kg/m<sup>2</sup> was used, the prevalence of OSA was 36%. A high risk for OSA is associated with a higher prevalence of depression, a higher number of psychiatric comorbidities, diabetes mellitus, a higher mean total chlorpromazine equivalent dose, a higher number of total medications, poorer quality of life in some of the domains, and scored high for all domains and the total score of UKU.</p><p><strong>Conclusion: </strong>To conclude, this study suggests that a high risk of OSA is associated with the presence of depression, a higher number of psychiatric comorbidities, diabetes mellitus, use of higher total chlorpromazine equivalent dose, the total number of medications, poorer quality of life, and a higher prevalence of other side effects.</p>","PeriodicalId":13345,"journal":{"name":"Indian Journal of Psychiatry","volume":"66 12","pages":"1159-1164"},"PeriodicalIF":1.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11758977/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143046131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Indian Journal of PsychiatryPub Date : 2024-12-01Epub Date: 2024-12-12DOI: 10.4103/indianjpsychiatry.indianjpsychiatry_858_24
Boro Monalisa, Saharan Vivek, Dey Pranjal
{"title":"Sensorineural hearing loss in a patient treated with sertraline: A case report.","authors":"Boro Monalisa, Saharan Vivek, Dey Pranjal","doi":"10.4103/indianjpsychiatry.indianjpsychiatry_858_24","DOIUrl":"10.4103/indianjpsychiatry.indianjpsychiatry_858_24","url":null,"abstract":"","PeriodicalId":13345,"journal":{"name":"Indian Journal of Psychiatry","volume":"66 12","pages":"1177-1178"},"PeriodicalIF":1.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11758976/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143046248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Indian Journal of PsychiatryPub Date : 2024-12-01Epub Date: 2024-12-12DOI: 10.4103/indianjpsychiatry.indianjpsychiatry_504_24
Mamta Mor, Venkatachalam Jayaseelan, Shivanand Kattimani, Chitra Thyagaraju, N S Kubera, Mahadevan Duraiswamy
{"title":"Depression, anxiety, stress, and coping among men with infertility seeking treatment at a tertiary care hospital in South India: A mixed-method study.","authors":"Mamta Mor, Venkatachalam Jayaseelan, Shivanand Kattimani, Chitra Thyagaraju, N S Kubera, Mahadevan Duraiswamy","doi":"10.4103/indianjpsychiatry.indianjpsychiatry_504_24","DOIUrl":"10.4103/indianjpsychiatry.indianjpsychiatry_504_24","url":null,"abstract":"<p><strong>Background: </strong>Many studies in India and all over the world have focused on the psychological aspect of infertility in women, but only a few have explored it among men. To deal with psychological distress, sometimes, individuals may use maladaptive coping strategies which can further worsen the stress instead of reducing it.</p><p><strong>Aim: </strong>To assess symptoms of depression, anxiety, stress, and various coping strategies adopted by men with infertility along with exploring their coping experiences.</p><p><strong>Methods: </strong>A sequential explanatory mixed-method study was conducted in a tertiary care hospital in South India.The study was conducted among 200 men with infertility seeking treatment from a tertiary care hospital. The symptoms of depression, anxiety, and stress were assessed using Depression, Anxiety, Stress-21 scale, and coping strategies were assessed using Brief COPE scale. In-depth interviews were conducted among eight men who had moderate to severe symptoms of depression, anxiety, and stress.</p><p><strong>Results: </strong>The proportion of depressive symptoms was 46% (95% CI: 39.2-52.9), that of anxiety was 51% (95% CI: 44.1-57.8), and that of stress was 59.5% (95% CI: 52.5-66.0). The most common coping strategies used were planning (96.0%), active coping (91.5%), self-distraction (90.5%), and religion (89.5%). The analysis of qualitative data revealed three themes - emotional impact of infertility, coping mechanisms and support systems, and perception toward counseling to improve mental wellbeing.</p><p><strong>Conclusion: </strong>The study shows that the prevalence of symptoms of depression, anxiety, and stress is considerable among men with infertility. The majority of them were using problem-focused coping. Overall, the study highlights the need to diagnose and address mental health problems among men with infertility.</p>","PeriodicalId":13345,"journal":{"name":"Indian Journal of Psychiatry","volume":"66 12","pages":"1131-1138"},"PeriodicalIF":1.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11758972/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143046691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Indian Journal of PsychiatryPub Date : 2024-12-01Epub Date: 2024-12-12DOI: 10.4103/indianjpsychiatry.indianjpsychiatry_339_24
Naqib Ahmad Dost, Muhammad Haroon Stanikzai, Massoma Jafari
{"title":"Depression and anxiety symptoms among Afghan war widows and their associated factors: A cross-sectional analytical study.","authors":"Naqib Ahmad Dost, Muhammad Haroon Stanikzai, Massoma Jafari","doi":"10.4103/indianjpsychiatry.indianjpsychiatry_339_24","DOIUrl":"10.4103/indianjpsychiatry.indianjpsychiatry_339_24","url":null,"abstract":"<p><strong>Background: </strong>The 4 decades of conflict have particularly exacerbated the mental health of Afghan war widows, a population that has not been extensively studied in this context.</p><p><strong>Aim: </strong>This study aims to fill the gap in the literature by providing robust data on the prevalence of depression and anxiety symptoms and identifying associated factors among Afghan war widows.</p><p><strong>Methods: </strong>A cross-sectional study was carried out in 2023, interviewing war widows from four community health centers in Kandahar, Afghanistan. We employed a validated Patient Health Questionnaire and Generalized Anxiety Disorder Scale. A multivariable binary logistic regression model was used to determine factors associated with depression and anxiety symptoms.</p><p><strong>Results: </strong>The prevalence of depression and anxiety symptoms was 57.9% (95% CI: 52.7%-62.8%) and 61.5% (95% CI: 56.4%-66.4%), respectively. There were significant differences in the prevalence of mental health symptoms across our population with different sociodemographic and health-related profiles (in particular, time since widowhood, household income, history of comorbidity, and level of social support).</p><p><strong>Conclusion: </strong>The stark prevalence of mental health issues among Afghan war widows underscores an overlooked humanitarian crisis. The findings call for immediate mental health interventions, tailored to the sociopolitical realities of Afghanistan.</p>","PeriodicalId":13345,"journal":{"name":"Indian Journal of Psychiatry","volume":"66 12","pages":"1145-1149"},"PeriodicalIF":1.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11758968/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143046690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cortical hypometabolism as a predictor of intermittent theta burst stimulation response in treatment-resistant depression patients: An open-label study.","authors":"Nidhisha Bajaj, Nand Kumar, Rakesh Kumar, Vaibhav Patil, Anshul Sharma","doi":"10.4103/indianjpsychiatry.indianjpsychiatry_161_24","DOIUrl":"10.4103/indianjpsychiatry.indianjpsychiatry_161_24","url":null,"abstract":"<p><strong>Background: </strong>Intermittent theta burst stimulation (iTBS) is an accepted and approved brain stimulation technique to treat patients with treatment-resistant depression.</p><p><strong>Aim: </strong>Using neuroimaging, this open-label study aimed to predict the response by observing glucose metabolism with the help of 18-FDG PET scan.</p><p><strong>Methods: </strong>A total of 25 treatment-resistant depression patients received 15 sessions of iTBS on the left dorsolateral prefrontal cortex. Two FDG-PET scans were done for all the patients. Fifty-six percent of patients responded to treatment with iTBS.</p><p><strong>Results: </strong>We found that there was hypometabolism in left and right prefrontal lateral regions, left and right inferior parietal regions, and left prefrontal medial regions at baseline but no statistically significant difference in the metabolism between responders and nonresponders.</p><p><strong>Conclusion: </strong>We did not find any statistically significant difference in the metabolism between responders and nonresponders in any brain regions at T0 as well as T1. Further large-scale studies are required.</p>","PeriodicalId":13345,"journal":{"name":"Indian Journal of Psychiatry","volume":"66 12","pages":"1154-1158"},"PeriodicalIF":1.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11758971/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143046687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Indian Journal of PsychiatryPub Date : 2024-12-01Epub Date: 2024-12-12DOI: 10.4103/indianjpsychiatry.indianjpsychiatry_1095_24
{"title":"Erratum: Amend the Mental Health Care Act 2017: A Survey of Indian Psychiatrists (Paper 1).","authors":"","doi":"10.4103/indianjpsychiatry.indianjpsychiatry_1095_24","DOIUrl":"10.4103/indianjpsychiatry.indianjpsychiatry_1095_24","url":null,"abstract":"<p><p>[This corrects the article on p. 829 in vol. 66, PMID: 39502587.].</p>","PeriodicalId":13345,"journal":{"name":"Indian Journal of Psychiatry","volume":"66 12","pages":"1181"},"PeriodicalIF":1.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11758966/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143045820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of labor analgesia using programmed intermittent epidural boluses on postpartum depression symptoms: A randomized controlled trial.","authors":"Anmol Jindal, Sukanya Mitra, Jasveer Singh, Subodh Kumar, Poonam Goel, Subhash Das","doi":"10.4103/indianjpsychiatry.indianjpsychiatry_245_24","DOIUrl":"10.4103/indianjpsychiatry.indianjpsychiatry_245_24","url":null,"abstract":"<p><strong>Background: </strong>Postpartum depression (PPD) is a serious concern with multifactorial etiology. Association between prenatal anxiety, pain, and depression has been theorized.</p><p><strong>Aim: </strong>In this randomized controlled trial, we studied the effect of pain relief by combined spinal epidural (CSE) and other factors influencing PPD.</p><p><strong>Methods: </strong>After thorough assessment and obtaining prenatal baseline parameters, parturients were randomly assigned to group 1 (CSE) and group 2 (control) (n = 31 each). Group 1 received 0.5 ml of 0.5% hyperbaric bupivacaine with 12.5 mcg of fentanyl intrathecally and 6 ml of 0.1% levobupivacaine with 2 mcg/ml fentanyl programmed intermittent epidural bolus every 60 min and patient-controlled epidural analgesia (PCEA) bolus of the same drug with a lockout interval of 15 min. Group 2 underwent normal vaginal delivery without neuraxial analgesia. Patients in both the groups were assessed for PPD using Edinburgh Postnatal Depression Scale (EPDS) at day 3 and 6 weeks postpartum.</p><p><strong>Results: </strong>The EPDS score at 6 weeks postpartum was significantly lower in group 1 than in group 2 (<i>P</i> < 0.05). The pain score assessed using visual analog scale was significantly lesser in group 1 than in group 2 (<i>P</i> < 0.001). Multivariate linear regression analysis showed that prenatal anxiety, greater pain interference scores, and perceived stress were major determinants of PPD.</p><p><strong>Conclusion: </strong>CSE analgesia using PCEA pump with PIEB facility in laboring parturients resulted in lesser EPDS scores and hence lesser postpartum depression. Effective pain control may be an important component to prevent PPD.</p>","PeriodicalId":13345,"journal":{"name":"Indian Journal of Psychiatry","volume":"66 12","pages":"1124-1130"},"PeriodicalIF":1.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11758970/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143045421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Indian Journal of PsychiatryPub Date : 2024-12-01Epub Date: 2024-12-12DOI: 10.4103/indianjpsychiatry.indianjpsychiatry_586_24
Flavia di Michele
{"title":"Lithium absorption unpredictability after bariatric surgery: When different ways of administration of mood stabilizers should be prescribed.","authors":"Flavia di Michele","doi":"10.4103/indianjpsychiatry.indianjpsychiatry_586_24","DOIUrl":"10.4103/indianjpsychiatry.indianjpsychiatry_586_24","url":null,"abstract":"","PeriodicalId":13345,"journal":{"name":"Indian Journal of Psychiatry","volume":"66 12","pages":"1176-1177"},"PeriodicalIF":1.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11758961/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143045926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sociodemographic and clinical profiles of individuals with opioid dependence syndrome presenting to a tertiary care center in Assam: A retrospective review.","authors":"Pranjal J Chakravarty, Tathagata Mahintamani, Diptadhi Mukherjee, Partha P Daimary, Hemanta Dutta","doi":"10.4103/indianjpsychiatry.indianjpsychiatry_907_24","DOIUrl":"10.4103/indianjpsychiatry.indianjpsychiatry_907_24","url":null,"abstract":"<p><strong>Background: </strong>Opioid dependence is a critical public health issue in Northeast India, with limited data available on the affected population.</p><p><strong>Aim: </strong>This study examines the sociodemographic and clinical profiles of opioid-dependent individuals in Assam.</p><p><strong>Methods: </strong>A retrospective review was conducted of 238 patients diagnosed with opioid dependence at a tertiary care addiction treatment center in Assam, covering records from January 2022 to January 2023.</p><p><strong>Results: </strong>The sample consisted mainly of young, married males (median age 25 years), with a median 24-month dependence duration. Heroin was the primary opioid, and 55.5% had a history of injecting drug use (IDU). Among injection drug users (IDUs), 83.3% were positive for HCV, 9.8% for HBV, and 28.0% for HIV. Early onset of heroin use and unmarried status were linked to higher HCV prevalence, while HIV prevalence showed no significant sociodemographic associations in IDUs.</p><p><strong>Conclusion: </strong>The high prevalence of IDU and associated infections underscores the need for targeted interventions and comprehensive treatment resources for opioid users in Assam.</p>","PeriodicalId":13345,"journal":{"name":"Indian Journal of Psychiatry","volume":"66 12","pages":"1165-1168"},"PeriodicalIF":1.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11758967/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143046273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Unveiling the landscape of antistigma interventions for individuals with substance use disorders: A scoping review.","authors":"Abhishek Ghosh, Babita Sharma, Arshia Sood, Kshitiz Sharma","doi":"10.4103/indianjpsychiatry.indianjpsychiatry_770_24","DOIUrl":"10.4103/indianjpsychiatry.indianjpsychiatry_770_24","url":null,"abstract":"<p><strong>Background: </strong>Stigma against persons living with substance use disorders (PLSUD) fosters social and health inequities.</p><p><strong>Aim: </strong>We aimed to map different populations targeted by antistigma interventions, analyze specific characteristics of these interventions, and identify and categorize the theoretical frameworks used in these interventions.</p><p><strong>Methods: </strong>We examined randomized controlled trials and quasi or pre-experimental studies targeting stigma against PLSUD. Using two English databases, our analysis involved mapping study populations, antistigma interventions, and trial characteristics through a narrative synthesis. We adhered to the Workgroup for Intervention Development and Evaluation Research (WIDER) checklist for assessing reporting quality. The Theoretical Domain Framework (TDF) identified intervention domains and constructs of the interventions.</p><p><strong>Results: </strong>Of 698 studies, 29 met eligibility, with three from low-middle-income countries: 12 studies addressed the public, 11 self, and 5 structural stigmas. Reduction in stigma or improvements in knowledge of and attitude toward PLSUD was observed in 23 studies. Eight used social contact-based interventions, and one used direct social contact. Other interventions were psychoeducation, collaborative community care and linkage to social services, acceptance and commitment therapy, and gatekeepers' training. Five focused on injection drug use stigma; others were not substance-specific. Most studies reported the characteristics of the recipients (n = 28), mode of delivery (n = 28), and delivery settings (n = 24). Adherence to delivery protocol was the least reported (n = 5). The number of theoretical domains varied: 18 studies had 1-5 domains, 3 studies had 10, and 8 studies had 6-9 domains.</p><p><strong>Conclusion: </strong>Social contact-based interventions show promise for PLSUD; future research must improve the quality of reporting and design theory-informed interventions.</p>","PeriodicalId":13345,"journal":{"name":"Indian Journal of Psychiatry","volume":"66 12","pages":"1101-1123"},"PeriodicalIF":1.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11758978/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143046432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}