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Successful treatment of trichilemmal carcinoma with distant metastasis using pembrolizumab: a case report and review 使用 pembrolizumab 成功治疗伴有远处转移的三叶肺癌：病例报告和综述
IF 2.8 4区 医学
Immunotherapy Pub Date : 2024-05-23 DOI: 10.1080/1750743x.2024.2353535
Lei Liu, Tengfei Long, Nannan Wei, Hongyan Zhang, Chaoliang Tang, Jin Gao
{"title":"Successful treatment of trichilemmal carcinoma with distant metastasis using pembrolizumab: a case report and review","authors":"Lei Liu, Tengfei Long, Nannan Wei, Hongyan Zhang, Chaoliang Tang, Jin Gao","doi":"10.1080/1750743x.2024.2353535","DOIUrl":"https://doi.org/10.1080/1750743x.2024.2353535","url":null,"abstract":"","PeriodicalId":13328,"journal":{"name":"Immunotherapy","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141105985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cost–effectiveness analysis of immune checkpoint inhibitors as first-line therapy in advanced biliary tract cancer 免疫检查点抑制剂作为晚期胆道癌一线疗法的成本效益分析
IF 2.8 4区 医学
Immunotherapy Pub Date : 2024-05-22 DOI: 10.1080/1750743x.2024.2347822
Ruizhe Liu, Yijia Zhao, Fenghao Shi, Jianhong Zhu, Junyan Wu, Min Huang, Kaifeng Qiu
{"title":"Cost–effectiveness analysis of immune checkpoint inhibitors as first-line therapy in advanced biliary tract cancer","authors":"Ruizhe Liu, Yijia Zhao, Fenghao Shi, Jianhong Zhu, Junyan Wu, Min Huang, Kaifeng Qiu","doi":"10.1080/1750743x.2024.2347822","DOIUrl":"https://doi.org/10.1080/1750743x.2024.2347822","url":null,"abstract":"","PeriodicalId":13328,"journal":{"name":"Immunotherapy","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141110276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neoadjuvant envafolimab in a patient with MSI-H/dMMR colon cancer: a case report and literature review 一名MSI-H/dMMR结肠癌患者的新辅助治疗恩伐单抗：病例报告和文献综述
IF 2.8 4区 医学
Immunotherapy Pub Date : 2024-05-20 DOI: 10.1080/1750743x.2024.2350355
Ziwei Chen, Jingrui Zhou, Weimin Chen, Tao Wu, Ke Lian, Tao Shen
{"title":"Neoadjuvant envafolimab in a patient with MSI-H/dMMR colon cancer: a case report and literature review","authors":"Ziwei Chen, Jingrui Zhou, Weimin Chen, Tao Wu, Ke Lian, Tao Shen","doi":"10.1080/1750743x.2024.2350355","DOIUrl":"https://doi.org/10.1080/1750743x.2024.2350355","url":null,"abstract":"","PeriodicalId":13328,"journal":{"name":"Immunotherapy","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141120921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sarcoidosis-like reactions in metastatic renal cell carcinoma patients treated with immune-based combinations 接受免疫复合物治疗的转移性肾细胞癌患者的肉样瘤样反应
IF 2.8 4区 医学
Immunotherapy Pub Date : 2024-05-16 DOI: 10.1080/1750743x.2024.2342222
M. Rizzo, G. Pezzicoli, Carlo Ganini, Luisa Carone, Anna Caliò, Matteo Brunelli, L. Cosmai, Camillo Porta
{"title":"Sarcoidosis-like reactions in metastatic renal cell carcinoma patients treated with immune-based combinations","authors":"M. Rizzo, G. Pezzicoli, Carlo Ganini, Luisa Carone, Anna Caliò, Matteo Brunelli, L. Cosmai, Camillo Porta","doi":"10.1080/1750743x.2024.2342222","DOIUrl":"https://doi.org/10.1080/1750743x.2024.2342222","url":null,"abstract":"","PeriodicalId":13328,"journal":{"name":"Immunotherapy","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140970152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Deterioration in multifocal motor neuropathy upon treatment of immune-related adverse events of checkpoint inhibition 治疗检查点抑制剂的免疫相关不良事件时，多灶性运动神经病恶化的情况
IF 2.8 4区 医学
Immunotherapy Pub Date : 2024-05-16 DOI: 10.1080/1750743x.2024.2342238
Vera Elisabeth Adreana Kleinveld, J. Wanschitz, Wolfgang N Löscher, Anna Hotter, Corinne Gosewina Cornelia Horlings
{"title":"Deterioration in multifocal motor neuropathy upon treatment of immune-related adverse events of checkpoint inhibition","authors":"Vera Elisabeth Adreana Kleinveld, J. Wanschitz, Wolfgang N Löscher, Anna Hotter, Corinne Gosewina Cornelia Horlings","doi":"10.1080/1750743x.2024.2342238","DOIUrl":"https://doi.org/10.1080/1750743x.2024.2342238","url":null,"abstract":"","PeriodicalId":13328,"journal":{"name":"Immunotherapy","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140968521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
What is the future of immune checkpoints inhibitors for metastatic triple negative breast cancers? 免疫检查点抑制剂治疗转移性三阴性乳腺癌的前景如何？
IF 2.8 4区 医学
Immunotherapy Pub Date : 2024-04-30 DOI: 10.2217/imt-2024-0030
Ramon Andrade de Mello, Kátia Roque Perez, Puteri Abdul Haris
{"title":"What is the future of immune checkpoints inhibitors for metastatic triple negative breast cancers?","authors":"Ramon Andrade de Mello, Kátia Roque Perez, Puteri Abdul Haris","doi":"10.2217/imt-2024-0030","DOIUrl":"https://doi.org/10.2217/imt-2024-0030","url":null,"abstract":"","PeriodicalId":13328,"journal":{"name":"Immunotherapy","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140863322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adherence, persistence and treatment switching in psoriasis. 银屑病的依从性、持续性和治疗转换。
IF 2.8 4区 医学
Immunotherapy Pub Date : 2024-04-23 DOI: 10.2217/imt-2023-0343
F. Santoleri, F. Musicco, Chiara Fulgenzio, P. Abrate, Laura Pestrin, Enrico Pasut, Germana Modesti, Romina Giannini, Stefania De Rosa, Mariantonietta Piccoli, Grazia Mingolla, Eva Zuzolo, Pietro Gazzola, Martina Roperti, Gabriella Pieri, Valentina Montresor, Isabella Martignoni, Marco Gambera, Roberto Langella, Gabriella Tinari, C. Spoltore, Cristina Roberti, Letizia Di Fabio, Laura Grossi, Francesca Guarino, F. D. Vita, R. Lasala, A. Costantini
{"title":"Adherence, persistence and treatment switching in psoriasis.","authors":"F. Santoleri, F. Musicco, Chiara Fulgenzio, P. Abrate, Laura Pestrin, Enrico Pasut, Germana Modesti, Romina Giannini, Stefania De Rosa, Mariantonietta Piccoli, Grazia Mingolla, Eva Zuzolo, Pietro Gazzola, Martina Roperti, Gabriella Pieri, Valentina Montresor, Isabella Martignoni, Marco Gambera, Roberto Langella, Gabriella Tinari, C. Spoltore, Cristina Roberti, Letizia Di Fabio, Laura Grossi, Francesca Guarino, F. D. Vita, R. Lasala, A. Costantini","doi":"10.2217/imt-2023-0343","DOIUrl":"https://doi.org/10.2217/imt-2023-0343","url":null,"abstract":"Aim: This study aims to investigate drug utilization patterns in the treatment of psoriasis (PsO) from 1 to 5 years in a real-life setting with Adalimumab (Ada), Etanercept (Eta), Ustekinumab (Ust), Golimumab (Gol), Ixekizumab (Ixe), Secukinumab (Sec) and Apremilast (Apr). Materials & methods: Data from an observational study were used to calculate adherence using the Proportion of Days Covered (PDC) method and persistence. Results & conclusion: Treatment adherence was found to be good for all the drugs studied across all years of analysis, while persistence was suboptimal, showing a marked decrease from the third year of study onward. In the treatment of PsO, greater attention needs to be paid to treatment persistence.","PeriodicalId":13328,"journal":{"name":"Immunotherapy","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140671960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Positioning risankizumab in the treatment algorithm of moderate-to-severe Crohn's disease 利桑珠单抗在中重度克罗恩病治疗算法中的定位
IF 2.8 4区 医学
Immunotherapy Pub Date : 2024-04-17 DOI: 10.2217/imt-2023-0219
Francesca Lusetti, Ferdinando D'Amico, Mariangela Allocca, Federica Furfaro, Alessandra Zilli, Gionata Fiorino, Tommaso Lorenzo Parigi, Simona Radice, Laurent Peyrin-Biroulet, Silvio Danese
{"title":"Positioning risankizumab in the treatment algorithm of moderate-to-severe Crohn's disease","authors":"Francesca Lusetti, Ferdinando D'Amico, Mariangela Allocca, Federica Furfaro, Alessandra Zilli, Gionata Fiorino, Tommaso Lorenzo Parigi, Simona Radice, Laurent Peyrin-Biroulet, Silvio Danese","doi":"10.2217/imt-2023-0219","DOIUrl":"https://doi.org/10.2217/imt-2023-0219","url":null,"abstract":"Risankizumab is a humanized monoclonal antibody that inhibits the p19 subunit of IL-23 cytokine. Recently it has been approved for the treatment of patients with moderate-to-severe Crohn's disease (CD). We conducted a scoping review to summarize the available data on risankizumab and to define its positioning in the treatment algorithm of CD. Pubmed, Embase and Scopus databases were searched up to Oct 31, 2023 to identify studies reporting efficacy and safety data of risankizumab in patients with CD. Risankizumab is an effective and safe drug for the management of patients with moderate-to-severe CD. It could be used as first-line therapy in biologic-naive patients and in patients who have previously failed other biological therapies.","PeriodicalId":13328,"journal":{"name":"Immunotherapy","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140611963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prognostic value of peripheral blood neutrophil/lymphocyte ratio, platelet/lymphocyte ratio, pan-immune-inflammation value and systemic immune-inflammation index for the efficacy of immunotherapy in patients with advanced gastric cancer 外周血中性粒细胞/淋巴细胞比值、血小板/淋巴细胞比值、泛免疫炎症值和全身免疫炎症指数对晚期胃癌患者免疫疗法疗效的预后价值
IF 2.8 4区 医学
Immunotherapy Pub Date : 2024-04-05 DOI: 10.2217/imt-2024-0031
Maodong Fu, Xiuping Zhang, Feng Shen, Jun Ma, Zhiyong Li
{"title":"Prognostic value of peripheral blood neutrophil/lymphocyte ratio, platelet/lymphocyte ratio, pan-immune-inflammation value and systemic immune-inflammation index for the efficacy of immunotherapy in patients with advanced gastric cancer","authors":"Maodong Fu, Xiuping Zhang, Feng Shen, Jun Ma, Zhiyong Li","doi":"10.2217/imt-2024-0031","DOIUrl":"https://doi.org/10.2217/imt-2024-0031","url":null,"abstract":"Aim: The study aimed to assess the value of pretreatment peripheral blood neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), pan-immune-inflammation value (PIV) and systemic immune-inflammation index (SII) for predicting immunotherapy prognosis and efficacy in advanced gastric cancer (GC). Methods: A total of 84 advanced GC patients received immunotherapy were retrospectively collected. The optimal cut-off values were determined by receiver operating characteristic curves. The univariate and multivariate analysis investigated the effects of NLR, PLR, PIV and SII on patients prognosis. Results: NLR, PLR, PIV and SII had predictive value of efficacy. NLR ≥3.65 was an independent risk factor for worse outcomes. Conclusion: NLR, PLR, PIV and SII have predictive value of efficacy and NLR ≥3.65 suggests a poor prognosis following immunotherapy in advanced GC.","PeriodicalId":13328,"journal":{"name":"Immunotherapy","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140571665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metastatic gastric cancer: synergizing and sequencing targeted therapy with first-line immunotherapy. 转移性胃癌：靶向治疗与一线免疫疗法的协同和排序。
IF 2.8 4区 医学
Immunotherapy Pub Date : 2024-04-01 Epub Date: 2024-03-12 DOI: 10.2217/imt-2024-0040
Gina Colarusso, Hiba Mechahougui, Thibaud Koessler, Alex Friedlaender
{"title":"Metastatic gastric cancer: synergizing and sequencing targeted therapy with first-line immunotherapy.","authors":"Gina Colarusso, Hiba Mechahougui, Thibaud Koessler, Alex Friedlaender","doi":"10.2217/imt-2024-0040","DOIUrl":"10.2217/imt-2024-0040","url":null,"abstract":"","PeriodicalId":13328,"journal":{"name":"Immunotherapy","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140101547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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