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Indian Journal of Pediatrics最新文献

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Bone Mineral Density and Its Association with Serum Biochemical Markers of Metabolic Bone Disease of Prematurity in Neonates of <34 weeks Gestation: Authors' Reply. <34孕周早产儿骨矿物质密度及其与代谢性骨病血清生化指标的关系：作者回复
IF 2.4 4区 医学
Indian Journal of Pediatrics Pub Date : 2026-11-01 Epub Date: 2026-09-25 DOI: 10.1007/s12098-026-06453-w
Hema Priya R, Suprabha K Patnaik
{"title":"Bone Mineral Density and Its Association with Serum Biochemical Markers of Metabolic Bone Disease of Prematurity in Neonates of <34 weeks Gestation: Authors' Reply.","authors":"Hema Priya R, Suprabha K Patnaik","doi":"10.1007/s12098-026-06453-w","DOIUrl":"10.1007/s12098-026-06453-w","url":null,"abstract":"","PeriodicalId":13320,"journal":{"name":"Indian Journal of Pediatrics","volume":" ","pages":"1252-1253"},"PeriodicalIF":2.4,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149060693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Congenital Thrombotic Thrombocytopenic Purpura Presenting as Isolated Thrombocytopenia: Correspondence. 先天性血栓性血小板减少性紫癜表现为孤立性血小板减少：对应。
IF 2.4 4区 医学
Indian Journal of Pediatrics Pub Date : 2026-11-01 Epub Date: 2026-09-01 DOI: 10.1007/s12098-026-06449-6
Sabavath Arun
{"title":"Congenital Thrombotic Thrombocytopenic Purpura Presenting as Isolated Thrombocytopenia: Correspondence.","authors":"Sabavath Arun","doi":"10.1007/s12098-026-06449-6","DOIUrl":"10.1007/s12098-026-06449-6","url":null,"abstract":"","PeriodicalId":13320,"journal":{"name":"Indian Journal of Pediatrics","volume":" ","pages":"1256"},"PeriodicalIF":2.4,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148874050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Urea / Albumin and CRP / Albumin Ratios as Predictors of Outcomes in Pediatric Sepsis - A Comparative Analysis of Mortality Prediction Using the PIM-3 Score. 尿素/白蛋白和CRP /白蛋白比率作为儿童脓毒症预后的预测因子——使用PIM-3评分预测死亡率的比较分析
IF 2.4 4区 医学
Indian Journal of Pediatrics Pub Date : 2026-11-01 Epub Date: 2026-08-28 DOI: 10.1007/s12098-026-06414-3
Abhishek A Thomas, Sheeja Sugunan
{"title":"Urea / Albumin and CRP / Albumin Ratios as Predictors of Outcomes in Pediatric Sepsis - A Comparative Analysis of Mortality Prediction Using the PIM-3 Score.","authors":"Abhishek A Thomas, Sheeja Sugunan","doi":"10.1007/s12098-026-06414-3","DOIUrl":"10.1007/s12098-026-06414-3","url":null,"abstract":"<p><p>Pediatric sepsis requires early risk identification to enable timely intervention, optimize resource allocation, and improve survival outcomes. This study aims to assess the validity of simple biomarkers, such as the Urea / Albumin ratio and the CRP / Albumin ratio, in predicting outcomes and to compare their performance with the Pediatric Index of Mortality-3 (PIM-3) score for predicting mortality. The cohort study was conducted at a Pediatric Intensive Care Unit (PICU) and included children aged 1 mo to 12 y with sepsis. For predicting mortality, the CRP / Albumin ratio (cut-off 21.5) had an Area Under the Curve (AUC) of 0.684, while the Urea / Albumin ratio (cut-off 8.28) and PIM-3 score showed an AUC of 0.852 and 0.830, respectively. The Urea / Albumin ratio showed comparable performance with the PIM-3 score. Additionally, the predictive performance for both ratios was modest for mechanical ventilation and acceptable for inotropes. A higher CRP / Albumin ratio was associated with longer PICU stays (≥5 d).</p>","PeriodicalId":13320,"journal":{"name":"Indian Journal of Pediatrics","volume":" ","pages":"1218-1220"},"PeriodicalIF":2.4,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148840314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bone Mineral Density and Its Association with Serum Biochemical Markers of Metabolic Bone Disease of Prematurity in Neonates of <34 weeks Gestation: Correspondence. <34孕周早产儿骨矿物质密度及其与代谢性骨病血清生化指标的关系：对应关系
IF 2.4 4区 医学
Indian Journal of Pediatrics Pub Date : 2026-11-01 Epub Date: 2026-09-04 DOI: 10.1007/s12098-026-06452-x
Soumya Jyoti Raha, Jogender Kumar
{"title":"Bone Mineral Density and Its Association with Serum Biochemical Markers of Metabolic Bone Disease of Prematurity in Neonates of <34 weeks Gestation: Correspondence.","authors":"Soumya Jyoti Raha, Jogender Kumar","doi":"10.1007/s12098-026-06452-x","DOIUrl":"10.1007/s12098-026-06452-x","url":null,"abstract":"","PeriodicalId":13320,"journal":{"name":"Indian Journal of Pediatrics","volume":" ","pages":"1251"},"PeriodicalIF":2.4,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148891625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical Outcomes and Hospitalization Cost of Minimally Invasive Surfactant Therapy vs. INSURE (Intubate-Surfactant-Extubate) Method in Neonates with Respiratory Distress Syndrome - Authors' Reply. 微创表面活性剂治疗与INSURE（插管-表面活性剂-拔管）法治疗新生儿呼吸窘迫综合征的临床疗效和住院费用——作者回复
IF 2.4 4区 医学
Indian Journal of Pediatrics Pub Date : 2026-11-01 Epub Date: 2026-09-16 DOI: 10.1007/s12098-026-06443-y
Ting Li, Xianglian Peng
{"title":"Clinical Outcomes and Hospitalization Cost of Minimally Invasive Surfactant Therapy vs. INSURE (Intubate-Surfactant-Extubate) Method in Neonates with Respiratory Distress Syndrome - Authors' Reply.","authors":"Ting Li, Xianglian Peng","doi":"10.1007/s12098-026-06443-y","DOIUrl":"10.1007/s12098-026-06443-y","url":null,"abstract":"","PeriodicalId":13320,"journal":{"name":"Indian Journal of Pediatrics","volume":" ","pages":"1261"},"PeriodicalIF":2.4,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148976668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Congenital Thrombotic Thrombocytopenic Purpura Presenting as Isolated Thrombocytopenia: Authors' Reply. 先天性血栓性血小板减少性紫癜表现为孤立性血小板减少：作者的答复。
IF 2.4 4区 医学
Indian Journal of Pediatrics Pub Date : 2026-11-01 Epub Date: 2026-09-18 DOI: 10.1007/s12098-026-06450-z
Vishvdeep Kishen Khushoo, Bablu Kumar Singh, Archit Sunil Pandharipande, Richa Juneja, Akriti Khare, Ketki Kedar, Santosh Govind Rathod
{"title":"Congenital Thrombotic Thrombocytopenic Purpura Presenting as Isolated Thrombocytopenia: Authors' Reply.","authors":"Vishvdeep Kishen Khushoo, Bablu Kumar Singh, Archit Sunil Pandharipande, Richa Juneja, Akriti Khare, Ketki Kedar, Santosh Govind Rathod","doi":"10.1007/s12098-026-06450-z","DOIUrl":"10.1007/s12098-026-06450-z","url":null,"abstract":"","PeriodicalId":13320,"journal":{"name":"Indian Journal of Pediatrics","volume":" ","pages":"1257"},"PeriodicalIF":2.4,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149001793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Shared Decision Making in the Neonatal Intensive Care Unit in Low Middle Income Countries - A Myth or A Path to Reality: Authors' Reply. 中低收入国家新生儿重症监护病房的共同决策——一个神话还是一条通往现实的道路：作者的回答。
IF 2.4 4区 医学
Indian Journal of Pediatrics Pub Date : 2026-11-01 Epub Date: 2026-09-15 DOI: 10.1007/s12098-026-06447-8
Bharathi Balachander, Vishnu Bhat Ballambattu
{"title":"Shared Decision Making in the Neonatal Intensive Care Unit in Low Middle Income Countries - A Myth or A Path to Reality: Authors' Reply.","authors":"Bharathi Balachander, Vishnu Bhat Ballambattu","doi":"10.1007/s12098-026-06447-8","DOIUrl":"10.1007/s12098-026-06447-8","url":null,"abstract":"","PeriodicalId":13320,"journal":{"name":"Indian Journal of Pediatrics","volume":" ","pages":"1259"},"PeriodicalIF":2.4,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148976713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Peripheral Vasopressor-Related Ischemia in a Preterm Infant. 外周血管加压剂相关的早产儿缺血。
IF 2.4 4区 医学
Indian Journal of Pediatrics Pub Date : 2026-11-01 Epub Date: 2026-09-28 DOI: 10.1007/s12098-026-06471-8
Mohnish Darshan, Chetan Khare, Amber Kumar
{"title":"Peripheral Vasopressor-Related Ischemia in a Preterm Infant.","authors":"Mohnish Darshan, Chetan Khare, Amber Kumar","doi":"10.1007/s12098-026-06471-8","DOIUrl":"10.1007/s12098-026-06471-8","url":null,"abstract":"","PeriodicalId":13320,"journal":{"name":"Indian Journal of Pediatrics","volume":" ","pages":"1223-1224"},"PeriodicalIF":2.4,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149074462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of Systemic Inflammation in Pediatric Rheumatic Diseases Using a Composite Systemic Inflammation Score. 用综合全身性炎症评分评价儿童风湿病的全身性炎症
IF 2.4 4区 医学
Indian Journal of Pediatrics Pub Date : 2026-11-01 Epub Date: 2026-09-16 DOI: 10.1007/s12098-026-06428-x
Debjani Bandhopadhyay, Biswabandhu Bankura, Avijit Hazra, Mihir Sarkar, Rakesh Kumar Mondal
{"title":"Evaluation of Systemic Inflammation in Pediatric Rheumatic Diseases Using a Composite Systemic Inflammation Score.","authors":"Debjani Bandhopadhyay, Biswabandhu Bankura, Avijit Hazra, Mihir Sarkar, Rakesh Kumar Mondal","doi":"10.1007/s12098-026-06428-x","DOIUrl":"10.1007/s12098-026-06428-x","url":null,"abstract":"<p><strong>Objectives: </strong>Isolated inflammatory markers have been proposed to assess systemic inflammation, but a comprehensive composite measure is still needed. The current study aimed to evaluate systemic inflammation in Pediatric Rheumatic Diseases by developing a biomarker-based composite systemic inflammation score (CSIS).</p><p><strong>Methods: </strong>This prospective observational study enrolled 117 children with rheumatic diseases-systemic-onset juvenile idiopathic arthritis (SOJIA), systemic lupus erythematosus (SLE), IgA vasculitis (IgAV), and Kawasaki disease (KD), along with 50 age, gender and temporal matched healthy controls. Associations between disease groups and inflammatory biomarkers [neutrophil-to-lymphocyte ratio (NLR), platelet count, ESR, CRP, D-dimer, procalcitonin, ferritin, fibrinogen, and albumin] were evaluated. The CSIS was developed using eight validated, routinely available parameters, with a total score ranging from 0 to 16. Prediction accuracy was evaluated with the area under the receiver operating characteristic curve (AUC).</p><p><strong>Results: </strong>Comparative analysis demonstrated significantly higher levels of inflammatory markers in patients than in controls, including NLR, platelet count, erythrocyte ESR, CRP, D-dimer, ferritin, fibrinogen, and albumin (all p <0.001). These eight significantly associated biomarkers were incorporated into the scoring systems' development. The CSIS was stratified into four categories to reflect the degree of inflammatory burden: 0-2 (no inflammation), >2-7 (mild inflammation), >7-10 (moderate inflammation), and >10 (severe inflammation).</p><p><strong>Conclusions: </strong>The CSIS can be readily applied to gauge inflammation severity in the clinical setting. Changes in inflammation scores over time can also reflect disease progression or remission, allowing for timely interventions and better outcomes.</p>","PeriodicalId":13320,"journal":{"name":"Indian Journal of Pediatrics","volume":" ","pages":"1183-1189"},"PeriodicalIF":2.4,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148976645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical and Hormonal Profile of Adolescents with PCOS and 'At Risk of PCOS': A Cross-Sectional Study. 青少年多囊卵巢综合征和“有多囊卵巢综合征风险”的临床和激素特征：一项横断面研究。
IF 2.4 4区 医学
Indian Journal of Pediatrics Pub Date : 2026-11-01 Epub Date: 2026-07-28 DOI: 10.1007/s12098-026-06338-y
Gamidi Meghana, Anju Seth, Preeti Singh, Pratip Jana, Ritu Singh, Kiran Aggarwal, Vibhu Mendiratta
{"title":"Clinical and Hormonal Profile of Adolescents with PCOS and 'At Risk of PCOS': A Cross-Sectional Study.","authors":"Gamidi Meghana, Anju Seth, Preeti Singh, Pratip Jana, Ritu Singh, Kiran Aggarwal, Vibhu Mendiratta","doi":"10.1007/s12098-026-06338-y","DOIUrl":"10.1007/s12098-026-06338-y","url":null,"abstract":"<p><strong>Objectives: </strong>To determine the frequency of polycystic ovary syndrome (PCOS) among symptomatic adolescents and to evaluate their clinical and hormonal profiles.</p><p><strong>Methods: </strong>Hundred post-menarcheal adolescents with menstrual irregularities, acne, and/or hirsutism were evaluated. Assessment included anthropometry, blood pressure, Ferriman-Gallwey (FG) scoring, acne grading and serum luteinizing hormone (LH), follicle-stimulating hormone (FSH), testosterone, sex hormone-binding globulin (SHBG), prolactin, and thyroid function tests. Free androgen index (FAI) was calculated. Participants were categorized as \"PCOS\" , \"at risk of PCOS\" , \"others\" , or \"normal\" per 2018 International Guidelines. Fifty age-matched healthy adolescents served as controls.</p><p><strong>Results: </strong>Among participants, 32% met criteria for PCOS, and 59% for 'at risk of PCOS'. Compared to 'at-risk' adolescents, those with PCOS had significantly higher BMI z-scores, serum LH, LH: FSH ratio, testosterone, and FAI. Over half of the affected adolescents were lean (17/32). Hyperandrogenemia markers (testosterone ≥2.1 nmol/L, FAI ≥97th percentile) and LH: FSH ≥3 were significantly more prevalent in the PCOS group. On multivariable logistic regression, FAI (AOR 1.18, 95% CI 1.06-1.33) and SHBG (AOR 1.08, 95% CI 1.04-1.14) were independently associated with PCOS/'at risk of PCOS' compared with controls. Among symptomatic adolescents, high FAI (AOR 1.26, 95% CI 1.07-1.56), and LH: FSH ratio (AOR 2.32, 95% CI 1.34-4.42) independently differentiated PCOS from the \"at risk of PCOS\" group.</p><p><strong>Conclusions: </strong>Adolescents with PCOS and those 'at risk' represent a spectrum with escalating hormonal abnormalities. Early identification of symptomatic adolescents, including lean individuals, are essential for targeted intervention and reduction of long-term risks.</p>","PeriodicalId":13320,"journal":{"name":"Indian Journal of Pediatrics","volume":" ","pages":"1162-1168"},"PeriodicalIF":2.4,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148602429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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