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Indian Journal of Pediatrics最新文献

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The Effects of the Late COVID-19 Period on Breastfeeding Practices: A Cohort Study. COVID-19晚期对母乳喂养行为的影响：一项队列研究
IF 2 4区 医学
Indian Journal of Pediatrics Pub Date : 2025-10-01 Epub Date: 2025-07-18 DOI: 10.1007/s12098-025-05671-y
Chrysoula Kosmeri, Vasileios Giapros, Dimitrios Rallis, Eleni Maragoudaki, Dimitris Kotsis, Natalia Atzemoglou, Anthitsa Pappa, Aikaterini Drougia
{"title":"The Effects of the Late COVID-19 Period on Breastfeeding Practices: A Cohort Study.","authors":"Chrysoula Kosmeri, Vasileios Giapros, Dimitrios Rallis, Eleni Maragoudaki, Dimitris Kotsis, Natalia Atzemoglou, Anthitsa Pappa, Aikaterini Drougia","doi":"10.1007/s12098-025-05671-y","DOIUrl":"10.1007/s12098-025-05671-y","url":null,"abstract":"","PeriodicalId":13320,"journal":{"name":"Indian Journal of Pediatrics","volume":" ","pages":"1127"},"PeriodicalIF":2.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144659104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Diagnostic Conundrum: Myoclonic Jerks, Prematurity, Dysmorphism, and Global Developmental Delay: Correspondence. 诊断难题：肌阵挛性抽搐、早产、畸形和整体发育迟缓：对应。
IF 2 4区 医学
Indian Journal of Pediatrics Pub Date : 2025-10-01 Epub Date: 2025-08-04 DOI: 10.1007/s12098-025-05702-8
Madhumita Nandi
{"title":"A Diagnostic Conundrum: Myoclonic Jerks, Prematurity, Dysmorphism, and Global Developmental Delay: Correspondence.","authors":"Madhumita Nandi","doi":"10.1007/s12098-025-05702-8","DOIUrl":"10.1007/s12098-025-05702-8","url":null,"abstract":"","PeriodicalId":13320,"journal":{"name":"Indian Journal of Pediatrics","volume":" ","pages":"1133"},"PeriodicalIF":2.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144784229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnostic Dilemma Between Autoimmune Encephalitis and SSPE: Case Report of Two Pediatric Patients - Correspondence. 自身免疫性脑炎和SSPE的诊断困境：两例儿科患者的病例报告-通信。
IF 2 4区 医学
Indian Journal of Pediatrics Pub Date : 2025-10-01 Epub Date: 2025-08-09 DOI: 10.1007/s12098-025-05713-5
Wen-Jing Chen, Sun-Yan Yan, Zhen-Zhen Wang
{"title":"Diagnostic Dilemma Between Autoimmune Encephalitis and SSPE: Case Report of Two Pediatric Patients - Correspondence.","authors":"Wen-Jing Chen, Sun-Yan Yan, Zhen-Zhen Wang","doi":"10.1007/s12098-025-05713-5","DOIUrl":"10.1007/s12098-025-05713-5","url":null,"abstract":"","PeriodicalId":13320,"journal":{"name":"Indian Journal of Pediatrics","volume":" ","pages":"1139"},"PeriodicalIF":2.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144804001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advocating Targeted Sequential Screening over Whole Exome Sequencing in 21-Hydroxylase Deficiency. 提倡对 21-羟化酶缺乏症进行有针对性的序列筛查而非全外显子组测序。
IF 2 4区 医学
Indian Journal of Pediatrics Pub Date : 2025-10-01 Epub Date: 2024-09-20 DOI: 10.1007/s12098-024-05249-0
Lavanya Ravichandran, Shriti Paul, A Rekha, Deny Varghese, R Parthiban, H S Asha, Sarah Mathai, Anna Simon, Sumita Danda, Nihal Thomas, Aaron Chapla
{"title":"Advocating Targeted Sequential Screening over Whole Exome Sequencing in 21-Hydroxylase Deficiency.","authors":"Lavanya Ravichandran, Shriti Paul, A Rekha, Deny Varghese, R Parthiban, H S Asha, Sarah Mathai, Anna Simon, Sumita Danda, Nihal Thomas, Aaron Chapla","doi":"10.1007/s12098-024-05249-0","DOIUrl":"10.1007/s12098-024-05249-0","url":null,"abstract":"<p><strong>Objectives: </strong>Whole exome sequencing (WES) has emerged as the preferred method for diagnosing a range of Mendelian disorders. Nonetheless, the applicability of WES in genetic diagnosis of 21-hydroxylase deficiency (21-OHD) remains uncertain due to the intricacies involved in molecular analysis of the CYP21A2 gene.</p><p><strong>Methods: </strong>In this case series, authors report the outcomes of couples or families who underwent WES followed by focused sequential strategy (FSS) targeting CYP21A2 gene hotspot mutations and targeted sequencing of genes associated with Congenital Adrenal Hyperplasia (CAH).</p><p><strong>Results: </strong>This analysis revealed that WES, when compared to FSS, resulted in six false-negative findings out of seven subjects and one false-positive result. These results were corroborated through validation using Multiplex Ligation-Dependent Probe Amplification (MLPA) and Sanger sequencing.</p><p><strong>Conclusions: </strong>One major limitation of exome sequencing lies in target enrichment, which often achieves less than 95% coverage of the regions of interest, potentially leading to false negatives. This challenge is particularly pronounced when deciphering the complex genetics of 21-OHD, characterized by intricate pseudogene-derived rearrangements and gene conversions. Additionally, next-generation sequencing (NGS) analysis of the CYP21A2 gene is not straightforward due to reads aligning to pseudogene regions, necessitating stringent computational pipelines with defined targets. However, simple genotyping assays have shown a high positive yield of pseudogene-derived mutations in over 80% of cases, while targeted NGS can be valuable in subjects with initially negative results. Therefore, WES is not recommended as the primary testing method for 21-OHD and may be better suited for rare forms of CAH once CYP21A2 mutations have been ruled out.</p>","PeriodicalId":13320,"journal":{"name":"Indian Journal of Pediatrics","volume":" ","pages":"1056-1061"},"PeriodicalIF":2.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142286052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ectopic Paragonimiasis Mimicking Orbital Cellulitis in a Child. 异位吸虫病模拟儿童眼眶蜂窝织炎。
IF 2 4区 医学
Indian Journal of Pediatrics Pub Date : 2025-10-01 Epub Date: 2025-07-10 DOI: 10.1007/s12098-025-05668-7
Qing Liu, Lin Chen, Junjie Xu, XuanXuan Xie
{"title":"Ectopic Paragonimiasis Mimicking Orbital Cellulitis in a Child.","authors":"Qing Liu, Lin Chen, Junjie Xu, XuanXuan Xie","doi":"10.1007/s12098-025-05668-7","DOIUrl":"10.1007/s12098-025-05668-7","url":null,"abstract":"","PeriodicalId":13320,"journal":{"name":"Indian Journal of Pediatrics","volume":" ","pages":"1130"},"PeriodicalIF":2.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144600268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Leg Pain Due to Chronic Hypoxic Ischemic Encephalopathy. 慢性缺氧缺血性脑病所致腿部疼痛。
IF 2 4区 医学
Indian Journal of Pediatrics Pub Date : 2025-10-01 Epub Date: 2025-07-14 DOI: 10.1007/s12098-025-05670-z
Umaserma Bharathi, Umapathy Pasupathy, Dinesh Kumar J, Pinnaka Subbarao, Preetha V
{"title":"Leg Pain Due to Chronic Hypoxic Ischemic Encephalopathy.","authors":"Umaserma Bharathi, Umapathy Pasupathy, Dinesh Kumar J, Pinnaka Subbarao, Preetha V","doi":"10.1007/s12098-025-05670-z","DOIUrl":"10.1007/s12098-025-05670-z","url":null,"abstract":"","PeriodicalId":13320,"journal":{"name":"Indian Journal of Pediatrics","volume":" ","pages":"1128"},"PeriodicalIF":2.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144626154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cor Triatriatum with Mixed Total Anomalous Pulmonary Venous Connection. 三房心伴混合性全异常肺静脉连接。
IF 2 4区 医学
Indian Journal of Pediatrics Pub Date : 2025-10-01 Epub Date: 2025-08-20 DOI: 10.1007/s12098-025-05715-3
Gurkawal Kaur, Anmol Bhatia, Jayashree Muralidharan, Kushaljit Singh Sodhi, Akshay Kumar Saxena
{"title":"Cor Triatriatum with Mixed Total Anomalous Pulmonary Venous Connection.","authors":"Gurkawal Kaur, Anmol Bhatia, Jayashree Muralidharan, Kushaljit Singh Sodhi, Akshay Kumar Saxena","doi":"10.1007/s12098-025-05715-3","DOIUrl":"10.1007/s12098-025-05715-3","url":null,"abstract":"","PeriodicalId":13320,"journal":{"name":"Indian Journal of Pediatrics","volume":" ","pages":"1111-1112"},"PeriodicalIF":2.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144952236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Open versus Closed Suctioning Among Mechanically Ventilated Pediatric Patients: A Randomised Control Trial - Authors' Reply-2. 在机械通气的儿科患者中开放与封闭吸引：一项随机对照试验-作者回复2。
IF 2 4区 医学
Indian Journal of Pediatrics Pub Date : 2025-10-01 Epub Date: 2025-09-02 DOI: 10.1007/s12098-025-05732-2
Subhranshu Sekhar Dhal, Manaswinee Sahoo
{"title":"Open versus Closed Suctioning Among Mechanically Ventilated Pediatric Patients: A Randomised Control Trial - Authors' Reply-2.","authors":"Subhranshu Sekhar Dhal, Manaswinee Sahoo","doi":"10.1007/s12098-025-05732-2","DOIUrl":"10.1007/s12098-025-05732-2","url":null,"abstract":"","PeriodicalId":13320,"journal":{"name":"Indian Journal of Pediatrics","volume":" ","pages":"1151"},"PeriodicalIF":2.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144952334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinicodemographic and Biochemical Profile of Children with Dengue Infection. 儿童登革热感染的临床人口学和生化特征。
IF 2 4区 医学
Indian Journal of Pediatrics Pub Date : 2025-10-01 DOI: 10.1007/s12098-025-05788-0
Koyel Mukhuty, Mansi Arora, Sakshi Kapoor, Anju Aggarwal, Vikram Bhasker
{"title":"Clinicodemographic and Biochemical Profile of Children with Dengue Infection.","authors":"Koyel Mukhuty, Mansi Arora, Sakshi Kapoor, Anju Aggarwal, Vikram Bhasker","doi":"10.1007/s12098-025-05788-0","DOIUrl":"10.1007/s12098-025-05788-0","url":null,"abstract":"","PeriodicalId":13320,"journal":{"name":"Indian Journal of Pediatrics","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145199196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of Tele-Kangaroo Mother Care (KMC) Clinics on the Respiratory Outcomes of Newborns. 远程袋鼠妈妈护理（KMC）诊所对新生儿呼吸结局的影响。
IF 2 4区 医学
Indian Journal of Pediatrics Pub Date : 2025-10-01 Epub Date: 2025-04-12 DOI: 10.1007/s12098-025-05528-4
Nikita Agarwal, Rohit Anand, Atul Jindal, Rajesh Baghel, Rudra Kashyap, Geeta Nag, Jyoti Bharti, Gajendra Singh
{"title":"Impact of Tele-Kangaroo Mother Care (KMC) Clinics on the Respiratory Outcomes of Newborns.","authors":"Nikita Agarwal, Rohit Anand, Atul Jindal, Rajesh Baghel, Rudra Kashyap, Geeta Nag, Jyoti Bharti, Gajendra Singh","doi":"10.1007/s12098-025-05528-4","DOIUrl":"10.1007/s12098-025-05528-4","url":null,"abstract":"<p><strong>Objectives: </strong>To assess the respiratory outcomes of newborns receiving Kangaroo mother care (KMC) in remote units of Chhattisgarh, India by providing telementoring to medical staff and parents.</p><p><strong>Methods: </strong>In 2022, this comparative study was carried out at one SNCU in Chhattisgarh, India. The study consisted of gathering data before intervention and utilizing video call technology for remote mentoring to encourage KMC among both staff and parents. Quality improvement initiatives were executed under supervision. Subsequently, data on mortality and morbidity was collected and compared with pre-intervention data.</p><p><strong>Results: </strong>The KMC rate increased from 4.5% to 100% by the end of 2022 and remained consistent in 2023. The median latency for starting KMC decreased to 0 d. Long KMC for more than 8 h was seen in 61.4% of babies who received KMC. Oxygen usage dropped from 93.4% to 39.8%. The median days of respiratory support decreased from 3 d to 0 d. The incidence of apnea reduced from 30.3% to 13%. Total adverse outcomes [death, leave-against-medical-advice (LAMA) and referral] reduced from 35.8% (n = 95) to 18.3% (n = 62) (p < 0.05) [Relative Risk (RR): 0.51; 95% Confidence Interval (CI): 0.39-0.67] CONCLUSIONS: Using telemedicine technology for promotion and maintenance of KMC is an effective approach to decrease the mortality rate, morbidity rate, and overall cost of care for newborns who are admitted to SNCUs located remotely.</p>","PeriodicalId":13320,"journal":{"name":"Indian Journal of Pediatrics","volume":" ","pages":"1092-1097"},"PeriodicalIF":2.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143977217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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