Indian Journal of Pediatrics最新文献

Predictors of High-Flow Nasal Cannula Failure in Preterm Neonates with Respiratory Distress Syndrome. 呼吸窘迫综合征早产儿高流量鼻插管失败的预测因素。

IF 2.4 4区医学

Indian Journal of Pediatrics Pub Date : 2026-09-07 DOI: 10.1007/s12098-026-06429-w

Hari Prasath C, P Anil Kumar, Indira P, Pentala Sripooja

引用次数: 0

Fighting a Dual Battle: The Harrowing Course of B/T Lineage Mixed Phenotype Acute Leukemia in a Child. 一场双重战斗：儿童B/T血统混合表型急性白血病的悲惨历程。

IF 2.4 4区医学

Indian Journal of Pediatrics Pub Date : 2026-09-05 DOI: 10.1007/s12098-026-06422-3

Nagarjun Sai Jaine, Abhishek Purohit, Siyaram Didel, Eveeta Baruah

引用次数: 0

Influenza B Infection Experience from a Pediatric Tertiary Center. 乙型流感感染的经验，从儿科三级中心。

IF 2.4 4区医学

Indian Journal of Pediatrics Pub Date : 2026-09-04 DOI: 10.1007/s12098-026-06435-y

S Likhita, Vinod H Ratageri, Mahesh S Kumar, Siddappa F Dandinavar

引用次数: 0

Bone Mineral Density and Its Association with Serum Biochemical Markers of Metabolic Bone Disease of Prematurity in Neonates of <34 weeks Gestation: Correspondence. <34孕周早产儿骨矿物质密度及其与代谢性骨病血清生化指标的关系：对应关系

IF 2.4 4区医学

Indian Journal of Pediatrics Pub Date : 2026-09-04 DOI: 10.1007/s12098-026-06452-x

Soumya Jyoti Raha, Jogender Kumar

引用次数: 0

BRAF V600E Positive Non Langerhans Cell Histiocytosis Presenting as Hemophagocytic Lymphocytosis in a Young Child. BRAF V600E阳性非朗格汉斯细胞组织细胞增多症在幼儿中表现为噬血细胞性淋巴细胞增多症。

IF 2.4 4区医学

Indian Journal of Pediatrics Pub Date : 2026-09-04 DOI: 10.1007/s12098-026-06440-1

Namrata Kaul, Jyoti Singhal, Vandana Arya, Manas Kalra, Nitin Mohan, Jyoti Kotwal

引用次数: 0

Prenatal Diagnosis and Genomics in India - Historical Review, Current Status and Road Ahead. 产前诊断和基因组学在印度-历史回顾，现状和道路前进。

IF 2.4 4区医学

Indian Journal of Pediatrics Pub Date : 2026-09-01 Epub Date: 2026-07-01 DOI: 10.1007/s12098-026-06239-0

Shagun Aggarwal, Shubha R Phadke

{"title":"Prenatal Diagnosis and Genomics in India - Historical Review, Current Status and Road Ahead.","authors":"Shagun Aggarwal, Shubha R Phadke","doi":"10.1007/s12098-026-06239-0","DOIUrl":"10.1007/s12098-026-06239-0","url":null,"abstract":"Objectives: To present an overview of the practice of prenatal diagnosis and genomics in India.Methods: This manuscript was compiled through review of published literature, survey of peers and professional experience of authors.Results: The field of prenatal diagnosis in India had its beginnings in the 1980s with advent of ultrasound machines and invasive procedures. The high prevalence of birth defects and genetic diseases in the population had been recognized by pediatricians and clinical geneticists as early as the 1950-60s. Various factors, like epidemiological transition with increasing contribution of genetic diseases and birth defects towards adverse health statistics, enhanced awareness of health care providers and policy makers, availability of trained manpower and rapid advancements in the field of genomics have all led to expansion of the field of prenatal diagnosis and genomics in the country since these early times. Medical termination of pregnancy has been legally allowed since 1971 and culturally acceptable to the majority. In the last four decades, advances in prenatal diagnosis have given women the option to make decisions about termination of pregnancy by earlier detection of fetal structural and genetic abnormalities.Conclusions: This study reviews the historical journey of the field in India and the current status. It also discusses the challenges faced by the country and the measures being undertaken to address the same.","PeriodicalId":13320,"journal":{"name":"Indian Journal of Pediatrics","volume":" ","pages":"4-12"},"PeriodicalIF":2.4,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148360575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gonadal Yolk Sac Tumor in a Child with Complete Androgen Insensitivity Syndrome. 完全性雄激素不敏感综合征患儿的卵黄囊瘤。

IF 2.4 4区医学

Indian Journal of Pediatrics Pub Date : 2026-09-01 Epub Date: 2026-05-28 DOI: 10.1007/s12098-026-06215-8

Mridna Jha, Manas Kalra, Satish Kumar Aggarwal, Archana Dayal Arya, Ratna Dua Puri, Anupam Sachdeva

引用次数: 0

Honoring the Legacy of Professor I.C. Verma: Shaping Minds, Empowering Generations. 纪念I.C.维尔马教授的遗产：塑造思想，赋予世代力量。

IF 2.4 4区医学

Indian Journal of Pediatrics Pub Date : 2026-09-01 Epub Date: 2026-07-21 DOI: 10.1007/s12098-026-06145-5

Ratna Dua Puri, Madhulika Kabra

引用次数: 0

Serum Soluble Programmed Death Ligand-1 (sPD-L1) as a Diagnostic Marker in Neonatal Sepsis. 血清可溶性程序性死亡配体-1 （sPD-L1）作为新生儿脓毒症的诊断标志物

IF 2.4 4区医学

Indian Journal of Pediatrics Pub Date : 2026-09-01 Epub Date: 2026-06-08 DOI: 10.1007/s12098-026-06241-6

Titto Abraham Varghese, Dhrithiman Shetty

{"title":"Serum Soluble Programmed Death Ligand-1 (sPD-L1) as a Diagnostic Marker in Neonatal Sepsis.","authors":"Titto Abraham Varghese, Dhrithiman Shetty","doi":"10.1007/s12098-026-06241-6","DOIUrl":"10.1007/s12098-026-06241-6","url":null,"abstract":"Objectives: To evaluate serum soluble programmed death ligand-1 (sPD-L1) levels in neonatal sepsis and assess its diagnostic performance, association with disease severity, and clinical outcomes.Methods: This prospective observational study was conducted in a tertiary-care neonatal intensive care unit. Neonates with suspected sepsis, defined according to National Neonatology Forum (NNF) 2021 guidelines, were enrolled after parental consent. Serum sPD-L1 levels were measured using enzyme-linked immunosorbent assay (ELISA). Comparisons were performed across early-onset and late-onset sepsis, culture-positive and culture-negative sepsis, presence of multi-organ dysfunction syndrome (MODS), and survival outcomes. Receiver operating characteristic (ROC) curve analysis was used to determine diagnostic accuracy.Results: Serum sPD-L1 levels were significantly elevated in neonates with sepsis. Higher levels were observed in early-onset sepsis, culture-positive sepsis, neonates with MODS, and non-survivors, indicating a positive association with disease severity and adverse outcomes. ROC analysis demonstrated good diagnostic performance, with an area under the curve of 0.86. A cut-off value of 85 pg/mL showed clinically meaningful diagnostic discrimination.Conclusions: Serum sPD-L1 is significantly elevated in neonatal sepsis and correlates with severity, organ dysfunction, and mortality. It may serve as a promising adjunct biomarker for early diagnosis and risk stratification in neonatal sepsis, warranting validation in larger multicentric studies.","PeriodicalId":13320,"journal":{"name":"Indian Journal of Pediatrics","volume":" ","pages":"939-943"},"PeriodicalIF":2.4,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148198867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Survival Following Paralytic Rabies Encephalomyelitis in a Toddler: Challenges in Confirmation of Diagnosis. 幼儿麻痹性狂犬病脑脊髓炎后的生存：确认诊断的挑战。

IF 2.4 4区医学

Indian Journal of Pediatrics Pub Date : 2026-09-01 Epub Date: 2026-06-23 DOI: 10.1007/s12098-026-06261-2

Arya James, Sai Vamshi Varanasi, Shikha Jain, Himali Meshram, Abhishek Madhura, Meena Rajeev Mishra, Reeta S Mani, M A Ashwini, Meenakshi Girish, Akash Bang

{"title":"Survival Following Paralytic Rabies Encephalomyelitis in a Toddler: Challenges in Confirmation of Diagnosis.","authors":"Arya James, Sai Vamshi Varanasi, Shikha Jain, Himali Meshram, Abhishek Madhura, Meena Rajeev Mishra, Reeta S Mani, M A Ashwini, Meenakshi Girish, Akash Bang","doi":"10.1007/s12098-026-06261-2","DOIUrl":"10.1007/s12098-026-06261-2","url":null,"abstract":"Rabies encephalitis, caused by rabies virus, is an almost uniformly fatal neurotropic infection once clinical disease develops. Classical presentations of furious rabies, typically associated with a definitive history of dog bite and characteristic features such as hydrophobia and aerophobia, progress rapidly to death. In contrast, atypical presentations, particularly paralytic rabies, often lack classical clinical features posing significant diagnostic challenges. Diagnostic confirmation may be further complicated by recent post-exposure vaccination, confounding antibody assays, while molecular detection remains technically demanding and limited in availability. With advances in intensive care, rare instances of survival have been reported, especially in children. The authors report the case of a 2-y-old toddler with history of dog bite, who presented with rapidly progressive quadriparesis, where the diagnosis of paralytic rabies was supported by rising CSF and serum rabies virus neutralising antibodies. The child survived following comprehensive intensive care and was successfully discharged after a six-week hospital stay.","PeriodicalId":13320,"journal":{"name":"Indian Journal of Pediatrics","volume":" ","pages":"986-988"},"PeriodicalIF":2.4,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148301424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0