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Indian Journal of Pediatrics最新文献

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Enhanced Survival of 22-25 Week Preterm Infants After Proactive Care Implementation: A Comparative Analysis of Two Time Periods. 积极护理实施后 22-25 周早产儿的存活率提高：两个时间段的对比分析。
IF 2.1 4区 医学
Indian Journal of Pediatrics Pub Date : 2025-08-01 Epub Date: 2024-06-05 DOI: 10.1007/s12098-024-05164-4
Sae Yun Kim, Jeongmin Shin, Moon Yeon Oh, Young-Ah Youn
{"title":"Enhanced Survival of 22-25 Week Preterm Infants After Proactive Care Implementation: A Comparative Analysis of Two Time Periods.","authors":"Sae Yun Kim, Jeongmin Shin, Moon Yeon Oh, Young-Ah Youn","doi":"10.1007/s12098-024-05164-4","DOIUrl":"10.1007/s12098-024-05164-4","url":null,"abstract":"<p><strong>Objectives: </strong>To investigate the impact of proactive perinatal care on periviable preterm infants before and after its implementation.</p><p><strong>Methods: </strong>This retrospective cohort study was conducted over a period of 10 y, from 2013 to 2019, referred to as Phase I, and from 2020 to 2022, referred to as Phase II. A total of 162 eligible infants born between 22<sup>0/7</sup> and 25<sup>6/7</sup> wk of gestation were included in this analysis.</p><p><strong>Results: </strong>A total of 125 infants were born in phase I, and 37 infants in phase II received proactive care with minimal handling. The mortality decreased from 54.4% to 24.3% (P = 0.001). The composite outcomes of severe brain injury or death, sepsis or death and necrotizing enterocolitis or death were also improved with proactive care. Gestational age [adjusted odds ratio (aOR) 0.900; 95% confidence interval (CI), 0.836-0.970], air leak syndrome (aOR 4.958; 95% CI, 1.681-14.624), massive pulmonary hemorrhage (aOR 4.944; 95% CI, 2.055-11.893), and birth in phase II (aOR 0.324; 95% CI, 0.115-0.912) were independently associated with mortality.</p><p><strong>Conclusions: </strong>The implementation of proactive care with minimal handling resulted in an increased survival rate and a reduction in the combined morbidities between the two time periods. The provision of proactive perinatal care with minimal handling is crucial for improving both the survival rates and clinical outcomes of these vulnerable infants.</p>","PeriodicalId":13320,"journal":{"name":"Indian Journal of Pediatrics","volume":" ","pages":"844-852"},"PeriodicalIF":2.1,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12279888/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141247832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Zinc-Copper Interaction in Preterm Neonates: Findings from a Randomized Controlled Trial. 锌-铜在早产儿中的相互作用：一项随机对照试验的结果。
IF 2.1 4区 医学
Indian Journal of Pediatrics Pub Date : 2025-08-01 Epub Date: 2025-05-31 DOI: 10.1007/s12098-025-05596-6
Nikitha Suvarna J, Tanmaya Metgud, Manisha Bhandankar
{"title":"Zinc-Copper Interaction in Preterm Neonates: Findings from a Randomized Controlled Trial.","authors":"Nikitha Suvarna J, Tanmaya Metgud, Manisha Bhandankar","doi":"10.1007/s12098-025-05596-6","DOIUrl":"10.1007/s12098-025-05596-6","url":null,"abstract":"","PeriodicalId":13320,"journal":{"name":"Indian Journal of Pediatrics","volume":" ","pages":"874"},"PeriodicalIF":2.1,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144191725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long Term Follow up of Short-Chain-L-3-Hydroxyacyl-CoA Dehydrogenase (SCHAD) Deficiency Causing Hypoglycemia and Developmental Delays in Two Syrian Brothers. 短链- l- 3-羟基酰基辅酶a脱氢酶（SCHAD）缺乏导致两名叙利亚兄弟低血糖和发育迟缓的长期随访
IF 2.1 4区 医学
Indian Journal of Pediatrics Pub Date : 2025-08-01 Epub Date: 2025-06-16 DOI: 10.1007/s12098-025-05611-w
Annie Li, Robert Stein, C Anthony Rupar, Chitra Prasad
{"title":"Long Term Follow up of Short-Chain-L-3-Hydroxyacyl-CoA Dehydrogenase (SCHAD) Deficiency Causing Hypoglycemia and Developmental Delays in Two Syrian Brothers.","authors":"Annie Li, Robert Stein, C Anthony Rupar, Chitra Prasad","doi":"10.1007/s12098-025-05611-w","DOIUrl":"10.1007/s12098-025-05611-w","url":null,"abstract":"","PeriodicalId":13320,"journal":{"name":"Indian Journal of Pediatrics","volume":" ","pages":"870"},"PeriodicalIF":2.1,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144301983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Meningococcal Sepsis in Close Family Contact of Umrah Pilgrim to Mecca Despite Pre-Travel Meningococcal Vaccination. 前往麦加朝觐的朝拜者在旅行前接种脑膜炎球菌疫苗后，家庭密切接触者出现脑膜炎球菌败血症。
IF 2.1 4区 医学
Indian Journal of Pediatrics Pub Date : 2025-08-01 Epub Date: 2025-06-14 DOI: 10.1007/s12098-025-05612-9
Rajakumar Padur Sivaraman, Tessa Antony, Poornima Manickavel, Lakshmi Ram, Purvaja Muthukumarasamy
{"title":"Meningococcal Sepsis in Close Family Contact of Umrah Pilgrim to Mecca Despite Pre-Travel Meningococcal Vaccination.","authors":"Rajakumar Padur Sivaraman, Tessa Antony, Poornima Manickavel, Lakshmi Ram, Purvaja Muthukumarasamy","doi":"10.1007/s12098-025-05612-9","DOIUrl":"10.1007/s12098-025-05612-9","url":null,"abstract":"","PeriodicalId":13320,"journal":{"name":"Indian Journal of Pediatrics","volume":" ","pages":"880"},"PeriodicalIF":2.1,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144293576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recurrent Neurotoxicity in Cobra Envenomation: Authors' Reply. 眼镜蛇中毒后复发性神经毒性：作者回复。
IF 2.1 4区 医学
Indian Journal of Pediatrics Pub Date : 2025-08-01 Epub Date: 2025-06-14 DOI: 10.1007/s12098-025-05614-7
Farzana Nasreen Kalathingal, Manish Kumar, Kriti Mohan, Mahima Mittal
{"title":"Recurrent Neurotoxicity in Cobra Envenomation: Authors' Reply.","authors":"Farzana Nasreen Kalathingal, Manish Kumar, Kriti Mohan, Mahima Mittal","doi":"10.1007/s12098-025-05614-7","DOIUrl":"10.1007/s12098-025-05614-7","url":null,"abstract":"","PeriodicalId":13320,"journal":{"name":"Indian Journal of Pediatrics","volume":" ","pages":"899"},"PeriodicalIF":2.1,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144293577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spontaneous Stage 4 TAPS in Extreme Preterm Monochorionic Twins. 极度早产单绒毛膜双胞胎的自发性4期TAPS。
IF 2.1 4区 医学
Indian Journal of Pediatrics Pub Date : 2025-08-01 Epub Date: 2025-06-19 DOI: 10.1007/s12098-025-05626-3
Deepika Rustogi, Roshni Venkatasamudram Mohan, Aayush Jain
{"title":"Spontaneous Stage 4 TAPS in Extreme Preterm Monochorionic Twins.","authors":"Deepika Rustogi, Roshni Venkatasamudram Mohan, Aayush Jain","doi":"10.1007/s12098-025-05626-3","DOIUrl":"10.1007/s12098-025-05626-3","url":null,"abstract":"","PeriodicalId":13320,"journal":{"name":"Indian Journal of Pediatrics","volume":" ","pages":"890"},"PeriodicalIF":2.1,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144325567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lipopolysaccharide (LPS)-Induced Tumor Necrosis Factor-Alpha (TNF-ɑ) Levels and Health Care Associated Infection (HAI) in Children with Multi-Organ Dysfunction Syndrome (MODS): Correspondence. 多器官功能障碍综合征（MODS）患儿脂多糖（LPS）诱导的肿瘤坏死因子- α (TNF- α)水平与保健相关感染（HAI）的相关性
IF 2.1 4区 医学
Indian Journal of Pediatrics Pub Date : 2025-08-01 Epub Date: 2025-06-21 DOI: 10.1007/s12098-025-05641-4
Yinying Chai, Yibo He, Shengliang Qiu
{"title":"Lipopolysaccharide (LPS)-Induced Tumor Necrosis Factor-Alpha (TNF-ɑ) Levels and Health Care Associated Infection (HAI) in Children with Multi-Organ Dysfunction Syndrome (MODS): Correspondence.","authors":"Yinying Chai, Yibo He, Shengliang Qiu","doi":"10.1007/s12098-025-05641-4","DOIUrl":"10.1007/s12098-025-05641-4","url":null,"abstract":"","PeriodicalId":13320,"journal":{"name":"Indian Journal of Pediatrics","volume":" ","pages":"900"},"PeriodicalIF":2.1,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144336489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical, Hormonal, and Genetic Spectrum of 46 XY Disorders of Sexual Development (DSD) Patients. 46 XY 性发育障碍 (DSD) 患者的临床、激素和遗传谱。
IF 2.1 4区 医学
Indian Journal of Pediatrics Pub Date : 2025-08-01 Epub Date: 2024-05-18 DOI: 10.1007/s12098-024-05144-8
Rajan Palui, Lavanya Ravichandran, Sadishkumar Kamalanathan, Aaron Chapla, Jayaprakash Sahoo, Niya Narayanan, Dukhabandhu Naik, Nihal Thomas
{"title":"Clinical, Hormonal, and Genetic Spectrum of 46 XY Disorders of Sexual Development (DSD) Patients.","authors":"Rajan Palui, Lavanya Ravichandran, Sadishkumar Kamalanathan, Aaron Chapla, Jayaprakash Sahoo, Niya Narayanan, Dukhabandhu Naik, Nihal Thomas","doi":"10.1007/s12098-024-05144-8","DOIUrl":"10.1007/s12098-024-05144-8","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the clinical, hormonal and genetic characteristics of 46XY disorders of sexual development (DSD) patients from South India.</p><p><strong>Methods: </strong>46XY DSD patients with a provisional diagnosis of 17β-hydroxysteroid dehydrogenase 3 (17BHSD3) deficiency, 5 alpha-reductase type 2 deficiency (5ARD2) or partial androgen insensitivity syndrome (PAIS) based on clinical and hormonal analysis were included in this study. All the patients underwent detailed clinical and hormonal evaluations. Targeted next-generation sequencing for all three genes (AR, HSD17B3, and SRD5A2) in parallel was carried out for all the included patients and their parents.</p><p><strong>Results: </strong>Based upon the clinical and hormonal analysis, among the 37 children with 46XY DSD in the present study, 21 children were diagnosed with 5ARD2, 10 with PAIS, and six with 17BHSD3 deficiency. However, genetic analysis revealed pathogenic mutations in nine patients - six in the AR gene, two in the SRD5A2 gene, and one in the HSD17B3 gene. The concordance rate between provisional hormonal and genetic diagnosis was only 22.2%. Two out of six subjects with AR gene variants were positive for somatic mosaicism.</p><p><strong>Conclusions: </strong>In the present study, a positive genetic diagnosis was detected in nine patients (24%), including five novel variants. In this study, mutations in the AR gene was the most reported. The authors did not find the testosterone: dihydrotestosterone (T: DHT) ratio to be an accurate hormonal diagnostic tool.</p>","PeriodicalId":13320,"journal":{"name":"Indian Journal of Pediatrics","volume":" ","pages":"836-843"},"PeriodicalIF":2.1,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140957246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Management of Compartmental Syndrome in a Child with Hemophilia. 血友病患儿间室综合征的处理。
IF 2.1 4区 医学
Indian Journal of Pediatrics Pub Date : 2025-08-01 Epub Date: 2025-06-08 DOI: 10.1007/s12098-025-05606-7
Varsha Haridas, Divakar Jose, Collins Noble, Prameela Joji
{"title":"Management of Compartmental Syndrome in a Child with Hemophilia.","authors":"Varsha Haridas, Divakar Jose, Collins Noble, Prameela Joji","doi":"10.1007/s12098-025-05606-7","DOIUrl":"10.1007/s12098-025-05606-7","url":null,"abstract":"","PeriodicalId":13320,"journal":{"name":"Indian Journal of Pediatrics","volume":" ","pages":"883"},"PeriodicalIF":2.1,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144247681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reversible Dilated Cardiomyopathy in a Neonate. 新生儿可逆性扩张型心肌病1例。
IF 2.1 4区 医学
Indian Journal of Pediatrics Pub Date : 2025-08-01 Epub Date: 2025-06-12 DOI: 10.1007/s12098-025-05607-6
Nan Luo, Yumei Ge, Dan Zhao, Ling Zeng, Diao Yu
{"title":"Reversible Dilated Cardiomyopathy in a Neonate.","authors":"Nan Luo, Yumei Ge, Dan Zhao, Ling Zeng, Diao Yu","doi":"10.1007/s12098-025-05607-6","DOIUrl":"10.1007/s12098-025-05607-6","url":null,"abstract":"","PeriodicalId":13320,"journal":{"name":"Indian Journal of Pediatrics","volume":" ","pages":"882"},"PeriodicalIF":2.1,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144274762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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