Indian journal of experimental biology最新文献_第8页

Association of immune status with haematology and inflammatory markers in treatment naïve HIV positive patients from a tertiary health care institute e HIV Positive Patients from a Tertiary Health Care Institute 三级卫生保健机构治疗幼稚HIV阳性患者的免疫状态与血液学和炎症标志物的相关性

IF 0.6 4区生物学

Indian journal of experimental biology Pub Date : 2023-06-28 DOI: 10.56042/ijeb.v61i07.2323

引用次数: 0

Hypermethylation and reduced expression of lipoprotein metabolism genes ABCG1, LIPC and PLTP in Obese and Diabetic subjects: Potential risk factors for Coronary artery disease 肥胖和糖尿病患者脂蛋白代谢基因ABCG1、LIPC和PLTP的高甲基化和表达减少：冠状动脉疾病的潜在危险因素

IF 0.6 4区生物学

Indian journal of experimental biology Pub Date : 2023-06-28 DOI: 10.56042/ijeb.v61i07.2212

引用次数: 0

Clinical features and biochemical parameters influencing mortality in COVID-19 patients — Retrospective study from Telangana, India 影响新冠肺炎患者死亡率的临床特征和生化参数——来自印度特伦甘纳的回顾性研究

IF 0.6 4区生物学

Indian journal of experimental biology Pub Date : 2023-06-28 DOI: 10.56042/ijeb.v61i07.2215

引用次数: 0

Antiepileptic effects of exenatide in penicillin induced acute epilepsy model in rats 艾塞那肽在青霉素诱导的大鼠急性癫痫模型中的抗癫痫作用

IF 0.6 4区生物学

Indian journal of experimental biology Pub Date : 2023-06-01 DOI: 10.56042/ijeb.v61i06.1931

Ay ş egül Yildiz, Süleyman Emre, Ayd ı n Him

{"title":"Antiepileptic effects of exenatide in penicillin induced acute epilepsy model in rats","authors":"Ay ş egül Yildiz, Süleyman Emre, Ayd ı n Him","doi":"10.56042/ijeb.v61i06.1931","DOIUrl":"https://doi.org/10.56042/ijeb.v61i06.1931","url":null,"abstract":"Glucagon-like peptide-1 receptors are widely expressed in the brain and its association with nitric oxide is suggestive of its role in epilepsy. In this study, we investigated the effects of exenatide, a glucagon-like peptide-1 receptor agonist, on the epileptiform activity induced by penicillin injection. The study used 72 male Wistar albino rats in 9 groups. All groups except the last group which received only exenatide, received intracortical penicillin injection to induce epileptiform activity. Exenatide was intraperitoneally injected in II-IV groups, at doses of 50, 100, 200 μ g/kg, respectively. Sodium nitroprusside (SNP) and N ω -nitro-L-arginine methyl ester (L-NAME) were injected to the V-VIII groups either alone or with exenatide. Electrocorticography was recorded for 3 h. While administration of 200 μ g/kg exenatide reduced the frequency of epileptiform activity, 50 and 100 μ g/kg doses of exenatide were not effective. When the effective dose of exenatide and the SNP were injected together the spike frequency decreased significantly. When the effective dose of exenatide was given with L-NAME spike frequency significantly decreased only between 90 and 110 min. There was no statistically significant difference in terms of latency and amplitude between the experimental groups. Exenatide had an anticonvulsant effect in penicillin-induced acute epilepsy model which is possibly via nitric oxide and include another pathway since its effect was partially blocked by L-NAME and potentiated by SNP.","PeriodicalId":13290,"journal":{"name":"Indian journal of experimental biology","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41887199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of chronic physiological stress on rat oocyte reserve: Role of IGF-1, AMH and Bcl-2 慢性生理应激对大鼠卵母细胞储备的影响：IGF-1、AMH和Bcl-2的作用

IF 0.6 4区生物学

Indian journal of experimental biology Pub Date : 2023-06-01 DOI: 10.56042/ijeb.v61i06.1929

Deniz Ercetin, M. Sapmaz-Metin, R. D. Topuz

{"title":"Effect of chronic physiological stress on rat oocyte reserve: Role of IGF-1, AMH and Bcl-2","authors":"Deniz Ercetin, M. Sapmaz-Metin, R. D. Topuz","doi":"10.56042/ijeb.v61i06.1929","DOIUrl":"https://doi.org/10.56042/ijeb.v61i06.1929","url":null,"abstract":"Ovarian activity has a complex physiology and is related to oocyte quality in women. This study investigates the effects of ovarian activity with chronic stress (CS) on behavioural parameters, estrous cycles, and ovarian follicular development in rats. Here, we examined the ovarian microenvironment against exposure to stress and to elucidate the stress-related ovarian molecular mechanisms. Twenty female Sprague-Dawley rats were divided into the control and the CS groups. The estrous cycle phases were detected by vaginal smear. Rats in the CS group were immobilized 1 h/day for 8 weeks. At the end of the experiment, all animals were subjected to behavioral tests in their metestrus phase and sacrificed on the other day (diestrus phase). The ovaries were harvested for histological analysis, blood samples were taken to measure cortisol levels. The immunoreactivities of ovarian IGF-1, AMH and Bcl-2 proteins were evaluated by immunohistochemistry. Here, we have studied CS-induced prolonged estrous cycles. We showed a lower number of developing follicles but the higher number of atretic follicles in the CS group’s ovaries. The dominant structure of ovarian histology was large interstitial glands. CS caused decreases in ovarian Bcl-2, IGF-1 and AMH immunoreactivities which have roles in follicular development. Also, anxiety was detected in CS-exposed animals. Our results showed that chronic restrainer stress can be a serious endocrine disrupter by reducing ovarian paracrine","PeriodicalId":13290,"journal":{"name":"Indian journal of experimental biology","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49136911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Plant growth regulators improved cutting induced physio-biochemical responses to postponement senescence in chrysanthemum 植物生长调节剂改善切割诱导的菊花延缓衰老的生理生化反应

IF 0.6 4区生物学

Indian journal of experimental biology Pub Date : 2023-06-01 DOI: 10.56042/ijeb.v61i06.1942

{"title":"Plant growth regulators improved cutting induced physio-biochemical responses to postponement senescence in chrysanthemum","authors":"","doi":"10.56042/ijeb.v61i06.1942","DOIUrl":"https://doi.org/10.56042/ijeb.v61i06.1942","url":null,"abstract":"The marketability of cut flowers relies on its postharvest longevity, making it crucial to develop technologies that can extend its vase life. The vase life in chrysanthemum is dependent upon floret senescence and leaf yellowing. In view of extending the vase life, the present study elucidates the implication of plant growth regulators viz. benzyl adenine (BA), thidiazuron (TDZ) and salicylic acid (SA) on postharvest performance and flower longevity of chrysanthemum stems. The harvested stems were treated with various concentrations viz. BA and SA at 50,100,150 and 200 µM and TDZ at 5,10,15 and 20 µM. Treatments containing 10 µM TDZ and 100 µM BA were most effective in improving the longevity (23.35 and 20.32 days respectively) of cut chrysanthemum stems. However, TDZ outplayed BA followed by SA extends the flower longevity through the maintenance of higher physiological and biochemical characteristics. Cluster analysis inferred that the treatments of 50 and100 µM BA and 5 and10 µM TDZ were found to be efficient in delaying floret senescence (24.01 days) and leaf yellowing (20.54 days) in cut chrysanthemum stems. Postharvest longevity exhibited a positive correlation with antioxidant activities, total soluble sugars and proteins, while it showed a negative correlation with anthocyanin and carotenoid contents. The results have demonstrated that use of growth regulators such as benzyl adenine, thidiazuron and salicylic acid may preserve the quality of cut chrysanthemum stems and delay their senescence","PeriodicalId":13290,"journal":{"name":"Indian journal of experimental biology","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43436784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Can neutrophil/lymphocyte ratio and mean platelet volume values be used as early markers in assessing the prognosis of patients with aneurysmal subarachnoid hemorrhage? 中性粒细胞/淋巴细胞比率和平均血小板体积值能否作为评估动脉瘤性蛛网膜下腔出血患者预后的早期标志物？

IF 0.6 4区生物学

Indian journal of experimental biology Pub Date : 2023-06-01 DOI: 10.56042/ijeb.v61i06.1928

Mehmet Yigit, Mehmet Huseyin, Akgul

{"title":"Can neutrophil/lymphocyte ratio and mean platelet volume values be used as early markers in assessing the prognosis of patients with aneurysmal subarachnoid hemorrhage?","authors":"Mehmet Yigit, Mehmet Huseyin, Akgul","doi":"10.56042/ijeb.v61i06.1928","DOIUrl":"https://doi.org/10.56042/ijeb.v61i06.1928","url":null,"abstract":"Inflammation plays an important role in cerebrovascular diseases, including intracerebral hemorrhage. Assessing the prognosis of such hemorrgage at early stage adds significance to treatment outcome. In this study, for the first time, we used neutrophil/lymphocyte (N/L) ratio and mean platelet volume (MPV) values as early markers in assessing the prognosis of patients with aneurysmal subarachnoid hemorrhage (SAH). This retrospective study included 50 patients with aneurysmal SAH who were diagnosed, hospitalized, treated, and follow-up with angiography between 2015 and 2016 (Gr. I). Blood count parameters and their clinical status after application (the first-arrival Glasgow coma score [GCS]) and at discharge (Glasgow outcome score [GOS]) were examined. The MPV value and N/L ratio were compared with that of the nonaneurysmatic control group (group 2, n = 50). The N/L ratio of Gr. I (median: 10.80) was significantly higher than that of the control group (median: 2.20) ( P <0.05). The GCS ( median: 10.0) and GOS ( median: 3.0) of Gr. I were significantly lower than those of the control group (median GCS: 15.00, median GOS: 5.00) ( P <0.05). MPV values were not different between the two groups ( P >0.05). In the aneurysm group, the higher the N/L ratio, the lower the GCS and GOS, while the lower the N/L ratio, the higher the GCS and GOS. In patients with aneurysmal SAH, the inflammation level was associated with disease severity, which can be considered as an early treatment and prognostic marker. The initial application of the N/L ratio may be important in assessing the prognosis, and a lower N/L ratio may be used as a simple, effective, and important marker to estimate the better prognosis of patients with aneurysmal SAH.","PeriodicalId":13290,"journal":{"name":"Indian journal of experimental biology","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47949870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Immunoprotection in mice immunized with native OmpH, recombinant OmpH and HS alum precipitated vaccine of Pasteurella multocida P52 against P. multocida challenge 多杀性巴氏杆菌P52天然OmpH、重组OmpH和HS明矾沉淀疫苗免疫小鼠对多杀性大肠杆菌攻击的免疫保护作用

IF 0.6 4区生物学

Indian journal of experimental biology Pub Date : 2023-06-01 DOI: 10.56042/ijeb.v61i06.1941

引用次数: 0

Biodegradability traits of Bacillus subtilis and Fusarium sp. on composting of different nonconventional protein source 枯草芽孢杆菌和镰刀菌在不同非常规蛋白源堆肥中的生物降解特性

IF 0.6 4区生物学

Indian journal of experimental biology Pub Date : 2023-06-01 DOI: 10.56042/ijeb.v61i06.1930

Ekinadose Orose, M. Azra, O. K. Wokeh

{"title":"Biodegradability traits of Bacillus subtilis and Fusarium sp. on composting of different nonconventional protein source","authors":"Ekinadose Orose, M. Azra, O. K. Wokeh","doi":"10.56042/ijeb.v61i06.1930","DOIUrl":"https://doi.org/10.56042/ijeb.v61i06.1930","url":null,"abstract":"Biodegradation of livestock processing waste is one of the more cost-effective, ecologically safe recycling methods that may preserve nutritional content and key amino acids useful in animal feed production. Here, we determined the biodegrading potentials of nonconventional feedstuffs using a combination of bacteria ( Bacillus subtilis ) and fungi ( Fusarium sp.). Five nonconventional feed types (feather meal, hair waste, egg membranes, horn hoof and horn) were selected and replicated in a 10 L plastic biocomposter for 7 weeks and observed for degradation by measuring changes in total organic carbon, temperature, phosphorus, potassium, pH, microbial counts and rate of degradation. Bacteria and fungi were inoculated inside the substrate after isolation and incubation. The effects of physicochemical and microbial counts were assessed. The biodegradability and optimal activity were observed. From the results, physico-parameters measured during the 7 weeks showed significant differences ( P <0.05) between substrates. The highest rate of decomposition, temperature, pH levels, total organic carbon, and total bacteria counts were recorded in feather meal, egg membrane, and hair waste. The weekly study showed that feather meal (68.79%, decompose faster than cow hoof (18.72%) egg membrane (60.89%) hair waste (62.82%) and cow horn (32.31%) during bio-composting. This finding has potential application in the treatment process of keratin wastes","PeriodicalId":13290,"journal":{"name":"Indian journal of experimental biology","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47012091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development of high frequency in vitro shoot regeneration system from leaves of apple cultivar ‘Oregon Spur’ and optimization of antibiotics concentration 苹果‘俄勒冈刺’叶片高频离体再生体系的建立及抗生素浓度优化

IF 0.6 4区生物学

Indian journal of experimental biology Pub Date : 2023-06-01 DOI: 10.56042/ijeb.v61i06.1945

引用次数: 0