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Indian journal of experimental biology最新文献

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Therapeutic effects of computerized tomography (CT)-guided percutaneous microwave ablation on malignant lung tumors CT引导下经皮微波消融治疗肺部恶性肿瘤的疗效观察
4区 生物学
Indian journal of experimental biology Pub Date : 2023-09-29 DOI: 10.56042/ijeb.v61i10.5839
{"title":"Therapeutic effects of computerized tomography (CT)-guided percutaneous microwave ablation on malignant lung tumors","authors":"","doi":"10.56042/ijeb.v61i10.5839","DOIUrl":"https://doi.org/10.56042/ijeb.v61i10.5839","url":null,"abstract":"Lung cancer is a common clinical malignancy. In this study, we aimed to evaluate the therapeutic effects of computerized tomography ()-guided percutaneous microwave ablation (MWA) on malignant lung tumors. Sixty patients in our hospital enrolled between January 2015 and January 2017 were picked up as subjects. They were allocated into control group (30 malignant lung cancer patients underwent chemotherapy) and observation group (thirty patients received CT-guided percutaneous MWA). Later, comparisons of the objective response rate, tumor markers in serum, prevalence rate of untoward effects, long-term survival rate, relapse rate and quality-of-life (QoL) score were implemented. MWA patients showed an objective response rate of 66.7% (the rate was 40.00% in chemotherapy group; P <0.05). Serum carcinoembryonic antigen (CEA), cancer antigen 125 (CA125) and CA153 had lower levels after MWA in both groups than those before MWA (P <0.05) (this tendency was especially striking in observation group; P <0.05). In MWA patients, totally 10.00% of patients showed untoward effects (this was 33.33% in chemotherapy patients; P <0.05). The QoL scores were higher after MWA in both groups than those before MWA (P <0.05), especially in the observation group (P <0.05). For patients with malignant lung tumors, CT-guided percutaneous MWA may augment the short-term efficacy, control the tumor progression, relieve the adverse reactions and long-term local recurrence, increase the survival rate for a long term and improve the QoL during survival.","PeriodicalId":13290,"journal":{"name":"Indian journal of experimental biology","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135199176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Protective effect of melatonin on cisplatin induced acute kidney injury: Role of regulation of heat shock proteins expressions 褪黑素对顺铂急性肾损伤的保护作用：对热休克蛋白表达的调节作用
IF 0.6 4区 生物学
Indian journal of experimental biology Pub Date : 2023-09-01 DOI: 10.56042/ijeb.v61i09.5135
{"title":"Protective effect of melatonin on cisplatin induced acute kidney injury: Role of regulation of heat shock proteins expressions","authors":"","doi":"10.56042/ijeb.v61i09.5135","DOIUrl":"https://doi.org/10.56042/ijeb.v61i09.5135","url":null,"abstract":"","PeriodicalId":13290,"journal":{"name":"Indian journal of experimental biology","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43571742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Physiological Consequences of Immune Aging at Organs Level: A Mini-review 免疫衰老在器官水平上的生理后果:一个小综述
IF 0.6 4区 生物学
Indian journal of experimental biology Pub Date : 2023-09-01 DOI: 10.56042/ijeb.v61i09.3638
{"title":"Physiological Consequences of Immune Aging at Organs Level: A Mini-review","authors":"","doi":"10.56042/ijeb.v61i09.3638","DOIUrl":"https://doi.org/10.56042/ijeb.v61i09.3638","url":null,"abstract":"","PeriodicalId":13290,"journal":{"name":"Indian journal of experimental biology","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44298619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development of recombinant sialidase (NanH) protein-based Indirect-ELISA for epidemiological survey of anti-Pasteurella multocida antibodies in bovines 重组唾液酸酶（NanH）蛋白间接ELISA用于牛多杀性巴氏杆菌抗体流行病学调查的研究
IF 0.6 4区 生物学
Indian journal of experimental biology Pub Date : 2023-09-01 DOI: 10.56042/ijeb.v61i09.3872
{"title":"Development of recombinant sialidase (NanH) protein-based Indirect-ELISA for epidemiological survey of anti-Pasteurella multocida antibodies in bovines","authors":"","doi":"10.56042/ijeb.v61i09.3872","DOIUrl":"https://doi.org/10.56042/ijeb.v61i09.3872","url":null,"abstract":"","PeriodicalId":13290,"journal":{"name":"Indian journal of experimental biology","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42575378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hepatoprotective activity of Trianthema portulacastrum against lipopolysaccharide/ D-galactosamine- induced hepatotoxicity in mice 马齿苋对脂多糖/ d -半乳糖胺所致小鼠肝毒性的保护作用
IF 0.6 4区 生物学
Indian journal of experimental biology Pub Date : 2023-09-01 DOI: 10.56042/ijeb.v61i09.3784
{"title":"Hepatoprotective activity of Trianthema portulacastrum against lipopolysaccharide/ D-galactosamine- induced hepatotoxicity in mice","authors":"","doi":"10.56042/ijeb.v61i09.3784","DOIUrl":"https://doi.org/10.56042/ijeb.v61i09.3784","url":null,"abstract":"","PeriodicalId":13290,"journal":{"name":"Indian journal of experimental biology","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47800955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Effect of KATP Openers and Blockers on AKT and mTOR mRNA Levels in the Hippocampus and Cortex of Rats with Penicillin-Induced Epilepsy KATP开放剂和阻滞剂对青霉素致癫痫大鼠海马和皮质AKT和mTOR mRNA水平的影响
IF 0.6 4区 生物学
Indian journal of experimental biology Pub Date : 2023-09-01 DOI: 10.56042/ijeb.v61i09.1547
{"title":"The Effect of KATP Openers and Blockers on AKT and mTOR mRNA Levels in the Hippocampus and Cortex of Rats with Penicillin-Induced Epilepsy","authors":"","doi":"10.56042/ijeb.v61i09.1547","DOIUrl":"https://doi.org/10.56042/ijeb.v61i09.1547","url":null,"abstract":"","PeriodicalId":13290,"journal":{"name":"Indian journal of experimental biology","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47296420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Determination of lithium toxicity by apoptosis and different biomarkers on Carassius auratus (Linn.) tissues 细胞凋亡和不同生物标志物对鲫鱼组织锂毒性的测定
IF 0.6 4区 生物学
Indian journal of experimental biology Pub Date : 2023-09-01 DOI: 10.56042/ijeb.v61i09.5115
{"title":"Determination of lithium toxicity by apoptosis and different biomarkers on Carassius auratus (Linn.) tissues","authors":"","doi":"10.56042/ijeb.v61i09.5115","DOIUrl":"https://doi.org/10.56042/ijeb.v61i09.5115","url":null,"abstract":"","PeriodicalId":13290,"journal":{"name":"Indian journal of experimental biology","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44921030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correlation between musculoskeletal ultrasound signs of gouty arthritis and disease activity 痛风性关节炎的肌肉骨骼超声征象与疾病活动度的相关性
IF 0.6 4区 生物学
Indian journal of experimental biology Pub Date : 2023-09-01 DOI: 10.56042/ijeb.v61i09.5188
{"title":"Correlation between musculoskeletal ultrasound signs of gouty arthritis and disease activity","authors":"","doi":"10.56042/ijeb.v61i09.5188","DOIUrl":"https://doi.org/10.56042/ijeb.v61i09.5188","url":null,"abstract":"","PeriodicalId":13290,"journal":{"name":"Indian journal of experimental biology","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48125480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Downregulation of Wnt/β-catenin self-renewal pathway in cervical cancer cells by polyphenolic compounds 多酚类化合物下调宫颈癌症细胞Wnt/β-catenin自我更新途径
IF 0.6 4区 生物学
Indian journal of experimental biology Pub Date : 2023-09-01 DOI: 10.56042/ijeb.v61i09.3875
{"title":"Downregulation of Wnt/β-catenin self-renewal pathway in cervical cancer cells by polyphenolic compounds","authors":"","doi":"10.56042/ijeb.v61i09.3875","DOIUrl":"https://doi.org/10.56042/ijeb.v61i09.3875","url":null,"abstract":"","PeriodicalId":13290,"journal":{"name":"Indian journal of experimental biology","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48046717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Corynoxine and corynoxine B enhance the antitumor activity of gemcitabine in Panc-1 cells via ROS-p38 signaling pathway 炔诺星和炔诺星B通过ROS-p38信号通路增强吉西他滨对Panc-1细胞的抗肿瘤活性
IF 0.6 4区 生物学
Indian journal of experimental biology Pub Date : 2023-07-31 DOI: 10.56042/ijeb.v61i08.3878
Limin Yin, Chaohong Shi, Zhong-xiang Zhang, Wensheng Wang, Ming Li
{"title":"Corynoxine and corynoxine B enhance the antitumor activity of gemcitabine in Panc-1 cells via ROS-p38 signaling pathway","authors":"Limin Yin, Chaohong Shi, Zhong-xiang Zhang, Wensheng Wang, Ming Li","doi":"10.56042/ijeb.v61i08.3878","DOIUrl":"https://doi.org/10.56042/ijeb.v61i08.3878","url":null,"abstract":"Pancreatic ductal adenocarcinoma (PDAC) is one of the most malignant tumors, and effective therapeutic interventions for PDAC are limited. While Corynoxine (Cory) and its isomer Cory B have been identified as autophagy inducers in neuronal cells, it remains unclear whether they exert a therapeutic effect on PDAC. Here, we performed cell counting kit-8 (CCK8), colony formation, 5-Ethynyl-2′-deoxyuridine (EDU) staining, TUNEL, and flow cytometry assays to evaluate the effects of Cory on PDAC. Western blotting was conducted to analyze the protein expression levels. We showed that Cory and Cory B enhanced cell growth arrest and pro-apoptotic effects of gemcitabine (Gem) on Gem-resistant Panc-1 cells. Mechanistic studies revealed that increased production of reactive oxygen species (ROS) and p38 activation were closely associated with Cory and Cory B-induced cell death. Pretreatment with ROS scavenger N-acetylcysteine blocked Cory and Cory B-induced cell death. Moreover, p38 inhibitor SB203580 prevented cell death induced by Cory and Cory B. Overall, Cory and Cory B increase the sensitivity of Gem-resistant Panc-1 cells to Gem through the activation of ROS-dependent p38 signaling pathway. Our results indicate that Cory and Cory B might be potential approaches for PDAC therapy.","PeriodicalId":13290,"journal":{"name":"Indian journal of experimental biology","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46626385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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