IF 2.7 3区医学

Hpb Pub Date : 2025-03-01 DOI: 10.1016/j.hpb.2024.11.012

Rosa Klotz , Thomas M. Pausch , Jörg Kaiser , Maximilian C. Joos , Rüdiger Hecktor , Azaz Ahmed , Colette Dörr-Harim , Arianeb Mehrabi , Martin Loos , Susanne Roth , Christoph W. Michalski , Christoph Kahlert

{"title":"ChatGPT vs. surgeons on pancreatic cancer queries: accuracy & empathy evaluated by patients and experts","authors":"Rosa Klotz , Thomas M. Pausch , Jörg Kaiser , Maximilian C. Joos , Rüdiger Hecktor , Azaz Ahmed , Colette Dörr-Harim , Arianeb Mehrabi , Martin Loos , Susanne Roth , Christoph W. Michalski , Christoph Kahlert","doi":"10.1016/j.hpb.2024.11.012","DOIUrl":"10.1016/j.hpb.2024.11.012","url":null,"abstract":"<div><h3>Background</h3><div>Artificial intelligence (AI) offers potential support in patient–clinician interactions, but its impact on such communication remains unexplored.</div></div><div><h3>Methods</h3><div>In this study, ChatGPT was compared with two pancreatic surgeons in responding to ten pancreatic cancer surgery-related questions, co-designed with the Patient Advisory Board of the Surgical Society's Study Center. A blind evaluation of these responses, considering content congruency and clarity for non-specialists, was conducted by patients and surgeons.</div></div><div><h3>Results</h3><div>From June 23 to July 21, 2023, 24 patients and 25 surgeons participated, of which eleven patients and ten surgeons completed the survey in full. Utilizing a quantitative scale from 1 (strong-disagreement) to 5 (full-agreement), consensus was observed among patients and specialists concerning the content delivered by ChatGPT. The metrics for comprehensibility to a non-specialist audience consistently showed positive reception. In the evaluation of empathetic resonance, ChatGPT's responses mirrored those of the surgeons in the patient's view. A significant proportion ranked Surgeon 1's contributions foremost, followed closely by ChatGPT.</div></div><div><h3>Discussion</h3><div>This study demonstrates that surgeons and ChatGPT answer common queries from patients regarding pancreatic cancer surgery comparable regarding reliability, lay comprehension and empathy as evaluated by patients and surgical experts. These findings highlight the potential of AI in enhancing patient-provider interactions.</div></div>","PeriodicalId":13229,"journal":{"name":"Hpb","volume":"27 3","pages":"Pages 311-317"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142822031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Utility of endoscopic ultrasound-guided fine needle aspiration for genetic analysis in pancreatic ductal adenocarcinoma 超声内镜引导下细针穿刺在胰腺导管腺癌遗传分析中的应用。

IF 2.7 3区医学

Hpb Pub Date : 2025-03-01 DOI: 10.1016/j.hpb.2024.11.009

Irene Ligato, Ana Garcia Garcia de Paredes, Sergio Lopez Duran, Irene Gonzalez Garcia, Amparo Benito Berlinches, Estefania Romio de las Heras, Alejandra Caminoa Lizarralde, Almudena Santon Roldan, Mercedes Rodriguez Garrote, Carmen-Guillen Ponce, Victor Defarges, Jose Ramon Foruny Olcina, Agustin Albillos, Enrique Vazquez Sequeiros

引用次数: 0

Microwave ablation versus radiofrequency ablation for hepatocellular carcinoma in patients with decompensated cirrhosis 微波消融术与射频消融术治疗失代偿期肝硬化患者的肝细胞癌。

IF 2.7 3区医学

Hpb Pub Date : 2025-03-01 DOI: 10.1016/j.hpb.2024.12.010

Hongli Yu , Yao Yang , Xinran Lin , Yinling Xu , Anna Ying , Boling Lu , Yuemin Feng , Xinya Zhao , Qiang Zhu , Hang Zheng

{"title":"Microwave ablation versus radiofrequency ablation for hepatocellular carcinoma in patients with decompensated cirrhosis","authors":"Hongli Yu , Yao Yang , Xinran Lin , Yinling Xu , Anna Ying , Boling Lu , Yuemin Feng , Xinya Zhao , Qiang Zhu , Hang Zheng","doi":"10.1016/j.hpb.2024.12.010","DOIUrl":"10.1016/j.hpb.2024.12.010","url":null,"abstract":"<div><h3>Background</h3><div>The efficacy of microwave ablation (MWA) and radiofrequency ablation (RFA) in hepatocellular carcinoma (HCC) patients with decompensated cirrhosis remains unclear.</div></div><div><h3>Methods</h3><div>A total of 315 patients with decompensated cirrhosis and HCC who underwent MWA or RFA were recruited. Recurrence beyond the Milan criteria (RBM), local tumor progression (LTP), overall survival (OS), and complications were evaluated and compared.</div></div><div><h3>Results</h3><div>After propensity score matching, the overall liver-related complication rates were 12.1 % in the current study. The cumulative RBM rates were lower in patients treated with MWA compared to those treated with RFA (21.9 % vs. 23.4 % at 1 year; 42.3 % vs. 66.8 % at 5 years; <em>p</em> = 0.016). In addition, lower cumulative rates of LTP were found in patients treated with MWA compared to those treated with RFA (6.2 % vs. 19.9 % at 1 year; 14.7 % vs. 27.8 % at 3 years; <em>p</em> = 0.032). The OS rates at 1 and 5 years were 89.9 % and 58.9 % in the MWA group, and 80.7 %, and 38.9 % in the RFA group, respectively (<em>p</em> = 0.105).</div></div><div><h3>Conclusion</h3><div>HCC patients with decompensated cirrhosis can undergo MWA or RFA with acceptable mortality, morbidity and liver-rated complications rates. MWA demonstrates superiority over RFA in tumor control.</div></div>","PeriodicalId":13229,"journal":{"name":"Hpb","volume":"27 3","pages":"Pages 377-384"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142909519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Next-generation sequencing demonstrates racial and sex differences in genomic profiling of hepatocellular carcinoma patients: an AACR GENIE project analysis 新一代测序显示了肝细胞癌患者基因组谱的种族和性别差异：AACR GENIE项目分析

IF 2.7 3区医学

Hpb Pub Date : 2025-03-01 DOI: 10.1016/j.hpb.2024.12.008

Diamantis I. Tsilimigras , Hunter Stecko , Dimitrios Moris , Timothy M. Pawlik

{"title":"Next-generation sequencing demonstrates racial and sex differences in genomic profiling of hepatocellular carcinoma patients: an AACR GENIE project analysis","authors":"Diamantis I. Tsilimigras , Hunter Stecko , Dimitrios Moris , Timothy M. Pawlik","doi":"10.1016/j.hpb.2024.12.008","DOIUrl":"10.1016/j.hpb.2024.12.008","url":null,"abstract":"<div><h3>Background</h3><div>Genomic variations related to racial and sex differences among patients with hepatocellular carcinoma (HCC) have not been investigated. We sought to characterize the mutational landscape of patients with HCC relative to race and sex.</div></div><div><h3>Methods</h3><div>The American Association for Cancer Research GENIE project (v16.0) was used to assess data on genomic variations among adult patients (>18 years) with HCC who underwent next-generation sequencing. Variations in 787 genes were identified and characterized relative to race and sex.</div></div><div><h3>Results</h3><div>Among 832 patients, 60.8 % of individuals were White, 7.7 % Black, and 12.4 % Asian (other/unknown:19.1 %). Most patients had genetic data from the primary tumor (71.2 %), whereas 17.2 % had metastatic disease sequenced (unknown:11.6 %). <em>TERT</em> mutations occurred more frequently in White (48.0 %) and Black (46.7 %) versus Asian (23.4 %) patients (q = 0.003), while <em>TP53</em> mutations were more common in Asian (48.6 %) versus Black (45.5 %) or White (33.1 %) individuals (q = 0.03). <em>TERT</em> (46.1 % vs. 28.6 %) and <em>CTNNB1</em> mutations (47.7 % vs. 29.3 %) were more likely to occur in males than females (both q < 0.05). Marked variations in prevalence of other common genetic HCC mutations were noted across different races and sexes.</div></div><div><h3>Conclusions</h3><div>Differences in mutational profiles of HCC patients highlight the importance of accruing diverse populations of patients to clinical trials.</div></div>","PeriodicalId":13229,"journal":{"name":"Hpb","volume":"27 3","pages":"Pages 371-376"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142927197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comment on: “Tumor burden score as a prognostic factor in patients with intermediate and locally advanced hepatocellular carcinoma undergoing liver resection” 评论：“肿瘤负荷评分作为中晚期和局部晚期肝细胞癌行肝切除术患者的预后因素”。

IF 2.7 3区医学

Hpb Pub Date : 2025-03-01 DOI: 10.1016/j.hpb.2024.12.004

You-Fei Wei, Yin-Feng Xu

引用次数: 0

The management of splanchnic vein thrombosis in acute pancreatitis: a global DELPHI consensus study 急性胰腺炎内脏静脉血栓形成的处理：一项全球DELPHI共识研究。

IF 2.7 3区医学

Hpb Pub Date : 2025-03-01 DOI: 10.1016/j.hpb.2024.12.002

Michael Scott , Mudassar Ghazanfar , John Windsor , George Ramsay , Mohamed Bekheit

{"title":"The management of splanchnic vein thrombosis in acute pancreatitis: a global DELPHI consensus study","authors":"Michael Scott , Mudassar Ghazanfar , John Windsor , George Ramsay , Mohamed Bekheit","doi":"10.1016/j.hpb.2024.12.002","DOIUrl":"10.1016/j.hpb.2024.12.002","url":null,"abstract":"<div><h3>Background</h3><div>Splanchnic vein thrombosis (SpVT) occurs in 17%–23 % of acute pancreatitis cases. Serious sequelae include hepatic and bowel ischaemia. However, management with therapeutic anticoagulation remains controversial due to potential bleeding risk. We aim to determine the level of consensus on prognosis, diagnosis, management, and outcomes of SpVT through a DELPHI process.</div></div><div><h3>Methods</h3><div>Using purposive, non-probability sampling and DELPHI methodology, 173 clinicians with experience of SpVT in acute pancreatitis were approached. From April 2022 to April 2023, a three-round DELPHI process was implemented to completion. A total of 88 statements were posed for ranking via a four-point Likert scale.</div></div><div><h3>Results</h3><div>The mean acute pancreatitis caseload per respondent per year was 68·0, 72·6 and 73·0 for DELPHI rounds 1,2 and 3 respectively. For SpVT anatomical location, there was strong consensus favouring anticoagulation for portal vein (89·1 %) and SMV thrombosis (90·9 %), and no consensus to treat splenic vein thrombosis (47·3 %). 74·1 % rejected radiological resolution as a definitive anticoagulation endpoint. Majority consensus favoured death, bleeding risk, bowel or liver ischaemia, hospital admission length and ITU admission as significant outcomes for experimental research design.</div></div><div><h3>Conclusion</h3><div>There was significant consensus for anticoagulation treatment of SpVT of the portal and superior mesenteric veins, especially with complete occlusion by thrombosis. Randomised controlled trials are required to grade management recommendations.</div></div>","PeriodicalId":13229,"journal":{"name":"Hpb","volume":"27 3","pages":"Pages 343-351"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142909521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Textbook outcome in liver surgery for intrahepatic cholangiocarcinoma: defining predictors of an optimal postoperative course using machine learning 肝内胆管癌肝手术的教科书结果：使用机器学习确定最佳术后病程的预测因素。

IF 2.7 3区医学

Hpb Pub Date : 2025-03-01 DOI: 10.1016/j.hpb.2024.12.013

Abdullah Altaf , Mujtaba Khalil , Miho Akabane , Zayed Rashid , Jun Kawashima , Shahzaib Zindani , Andrea Ruzzenente , Luca Aldrighetti , Todd W. Bauer , Hugo P. Marques , Guillaume Martel , Irinel Popescu , Matthew J. Weiss , Minoru Kitago , George Poultsides , Shishir K. Maithel , Carlo Pulitano , Feng Shen , François Cauchy , Bas G. Koerkamp , Timothy M. Pawlik

{"title":"Textbook outcome in liver surgery for intrahepatic cholangiocarcinoma: defining predictors of an optimal postoperative course using machine learning","authors":"Abdullah Altaf , Mujtaba Khalil , Miho Akabane , Zayed Rashid , Jun Kawashima , Shahzaib Zindani , Andrea Ruzzenente , Luca Aldrighetti , Todd W. Bauer , Hugo P. Marques , Guillaume Martel , Irinel Popescu , Matthew J. Weiss , Minoru Kitago , George Poultsides , Shishir K. Maithel , Carlo Pulitano , Feng Shen , François Cauchy , Bas G. Koerkamp , Timothy M. Pawlik","doi":"10.1016/j.hpb.2024.12.013","DOIUrl":"10.1016/j.hpb.2024.12.013","url":null,"abstract":"<div><h3>Background</h3><div>We sought to define textbook outcome in liver surgery (TOLS) for intrahepatic cholangiocarcinoma (ICC) by considering the implications of perioperative outcomes on overall survival (OS).</div></div><div><h3>Methods</h3><div>Using a multi-institutional database, TOLS for ICC was defined by employing novel machine learning (ML) models to identify perioperative factors most strongly predictive of OS ≥ 12 months. Subsequently, clinicopathologic factors associated with achieving TOLS were investigated.</div></div><div><h3>Results</h3><div>A total of 1556 patients with ICC were included. The ML classification models demonstrated that the absence of post-hepatectomy liver failure, intraoperative blood loss <750 mL, absence of major infectious complications, and R0 resection were the perioperative outcomes associated with prolonged OS, thereby defining TOLS for ICC. On multivariable analysis, older age, ASA class >2, lymph node metastasis, receipt of neoadjuvant therapy, advanced T status, poor histological grade and microvascular invasion were independently associated with lower odds of achieving TOLS (all <em>p</em>-values<0.05). Overall, 60.2 % (<em>n</em> = 936) of the patients achieved TOLS, demonstrating markedly improved OS and recurrence-free survival (RFS) than individuals who did not (both <em>p</em> < 0.05).</div></div><div><h3>Conclusion</h3><div>A standardized definition of TOLS for ICC was established that may be used to evaluate hospital performance at the patient level and help optimize surgical outcomes for patients with ICC.</div></div>","PeriodicalId":13229,"journal":{"name":"Hpb","volume":"27 3","pages":"Pages 402-413"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142927198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Research Letter: variability in anticoagulation practices following pancreatic surgery with vascular resection 研究报告：胰腺血管切除术后抗凝治疗的变异性。

IF 2.7 3区医学

Hpb Pub Date : 2025-03-01 DOI: 10.1016/j.hpb.2024.11.010

Artur Rebelo, Shailesh Shrikhande, Qiaofei Liu, Johannes Klose, Jörg Kleeff, Peter Szatmary

引用次数: 0

Percutaneous hepatic artery infusion chemotherapy with oxaliplatin and fluoropyrimidines in treatment-resistant colorectal cancer patients with unresectable liver metastases: a retrospective cohort study 经皮肝动脉输注奥沙利铂和氟嘧啶类药物化疗不可切除肝转移的耐药结直肠癌患者：一项回顾性队列研究。

IF 2.7 3区医学

Hpb Pub Date : 2025-03-01 DOI: 10.1016/j.hpb.2024.11.008

William Pat Fong , Zi-Jing Li , Chao Ren , Wen-Long Guan , Meng-Xuan Zuo , Tian-Qi Zhang , Bin-Kui Li , Yun Zheng , Xiao-Jun Wu , Pei-Rong Ding , Gong Chen , Zhi-Zhong Pan , Yun-Fei Yuan , Qiong Tan , Zhi-Qiang Wang , Yu-Hong Li , De-Shen Wang

{"title":"Percutaneous hepatic artery infusion chemotherapy with oxaliplatin and fluoropyrimidines in treatment-resistant colorectal cancer patients with unresectable liver metastases: a retrospective cohort study","authors":"William Pat Fong , Zi-Jing Li , Chao Ren , Wen-Long Guan , Meng-Xuan Zuo , Tian-Qi Zhang , Bin-Kui Li , Yun Zheng , Xiao-Jun Wu , Pei-Rong Ding , Gong Chen , Zhi-Zhong Pan , Yun-Fei Yuan , Qiong Tan , Zhi-Qiang Wang , Yu-Hong Li , De-Shen Wang","doi":"10.1016/j.hpb.2024.11.008","DOIUrl":"10.1016/j.hpb.2024.11.008","url":null,"abstract":"<div><h3>Background</h3><div>Subsequent lines of therapy for chemotherapy-resistant metastatic colorectal cancer (CRC) have shown limited efficacy. Herein, we retrospectively investigated the efficacy and safety of hepatic artery infusion chemotherapy (HAIC) using oxaliplatin plus 5-FU/FUDR in patients with unresectable colorectal liver metastases (CRLM) who progressed following standard chemotherapy regimens.</div></div><div><h3>Methods</h3><div>From March 2017 to April 2023, CRC patients with unresectable CRLM who progressed following standard chemotherapy and subsequently received HAIC oxaliplatin plus 5-FU/FUDR were evaluated. Objective response rate (ORR), disease control rate (DCR), median depth of tumor response (DpR), no evidence of disease (NED) rate, progression-free survival (PFS), overall survival (OS), and safety were assessed.</div></div><div><h3>Results</h3><div>A total of 21 patients who progressed after a median of two (range: 1–4) lines of standard systemic chemotherapy were included. The ORR and DCR were 28.6 % and 95.2 %, respectively, with six patients reaching partial response. Additionally, the median DpR was 10.6 %, and seven patients underwent successful conversion surgery. Stratification revealed significantly better PFS in patients with liver-limited metastases compared to those with concurrent hepatic and extrahepatic metastases (<em>P</em> = 0.0003).</div></div><div><h3>Conclusion</h3><div>HAIC oxaliplatin plus 5-FU/FUDR is a robust regimen for treatment-resistant CRC patients with unresectable CRLM, particularly those with liver-limited disease.</div></div>","PeriodicalId":13229,"journal":{"name":"Hpb","volume":"27 3","pages":"Pages 289-298"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142817984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical features, risk factors, outcomes, and prediction model for intrahepatic and perihepatic abscess following hepatectomy for hepatocellular carcinoma 肝细胞癌肝切除术后肝内和肝周脓肿的临床特征、危险因素、结局和预测模型。

IF 2.7 3区医学

Hpb Pub Date : 2025-03-01 DOI: 10.1016/j.hpb.2024.12.003

Shuo Zhu , Li-Hui Gu , Yang Shen , Gui-Lin Xie , Qing-Xin Zhuang , Yong-Yi Zeng , Xue-Dong Wang , Ya-Hao Zhou , Wei-Min Gu , Hong Wang , Ting-Hao Chen , Yao-Ming Zhang , Hong-Wei Guo , Ying-Jian Liang , Xian-Ming Wang , Wan-Guang Zhang , Lei Cai , Chao Li , Lan-Qing Yao , Ming-Da Wang , Tian Yang

{"title":"Clinical features, risk factors, outcomes, and prediction model for intrahepatic and perihepatic abscess following hepatectomy for hepatocellular carcinoma","authors":"Shuo Zhu , Li-Hui Gu , Yang Shen , Gui-Lin Xie , Qing-Xin Zhuang , Yong-Yi Zeng , Xue-Dong Wang , Ya-Hao Zhou , Wei-Min Gu , Hong Wang , Ting-Hao Chen , Yao-Ming Zhang , Hong-Wei Guo , Ying-Jian Liang , Xian-Ming Wang , Wan-Guang Zhang , Lei Cai , Chao Li , Lan-Qing Yao , Ming-Da Wang , Tian Yang","doi":"10.1016/j.hpb.2024.12.003","DOIUrl":"10.1016/j.hpb.2024.12.003","url":null,"abstract":"<div><h3>Background</h3><div>Intrahepatic and perihepatic abscess (IPHA) is a severe yet understudied complication that can occur after hepatectomy. This multicenter study aimed to elucidate the clinical features, risk factors, and outcomes of IPHA after hepatectomy for hepatocellular carcinoma (HCC), and to develop a novel prediction model for personalized risk assessment.</div></div><div><h3>Methods</h3><div>This was a multicenter cohort study of HCC patients who underwent curative-intent hepatectomy. IPHA was defined as an imaging-confirmed abscess located in the hepatic or perihepatic space within 30 days after surgery. A nomogram-based prediction model was developed using preoperative and intraoperative variables, and its performance was evaluated by the concordance index (C-index).</div></div><div><h3>Results</h3><div>Among the 4621 patients identified, 154 (3.3 %) developed IPHA. IPHA was associated with significantly prolonged hospital stays (median: 16 <em>vs.</em> 11 days, <em>P</em> < 0.001), increased 30-day readmission rates (33.0 % <em>vs.</em> 3.1 %, <em>P</em> < 0.001), and higher 90-day mortality (11.7 % <em>vs.</em> 2.8 %, <em>P</em> < 0.001). Multivariate analysis identified obesity, diabetes mellitus, portal hypertension, major hepatectomy, open surgery, and intraoperative diaphragmatic incision as independent risk factors. The prediction model demonstrated robust discrimination (C-index: 0.747) and calibration.</div></div><div><h3>Conclusions</h3><div>IPHA significantly impacts postoperative outcomes following HCC resection. The novel prediction model aids in preoperative risk assessment to improve patient outcomes.</div></div>","PeriodicalId":13229,"journal":{"name":"Hpb","volume":"27 3","pages":"Pages 352-361"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142885820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

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