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Retraction Note: Long noncoding RNA LINC00460 promotes the progression of cervical cancer via regulation of the miR-361-3p/Gli1 axis 注:长链非编码RNA LINC00460通过调控miR-361-3p/Gli1轴促进宫颈癌的进展
IF 4.3 3区 生物学
Human Cell Pub Date : 2022-05-18 DOI: 10.1007/s13577-022-00723-3
Fan Li, Weipei Zhu, Zhijie Wang
{"title":"Retraction Note: Long noncoding RNA LINC00460 promotes the progression of cervical cancer via regulation of the miR-361-3p/Gli1 axis","authors":"Fan Li, Weipei Zhu, Zhijie Wang","doi":"10.1007/s13577-022-00723-3","DOIUrl":"https://doi.org/10.1007/s13577-022-00723-3","url":null,"abstract":"","PeriodicalId":13228,"journal":{"name":"Human Cell","volume":"35 1","pages":"1306 - 1306"},"PeriodicalIF":4.3,"publicationDate":"2022-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46372041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
KAT2A affects tumor metabolic reprogramming in colon cancer progression through epigenetic activation of E2F1 KAT2A通过表观遗传学激活E2F1影响结肠癌癌症进展中的肿瘤代谢重编程
IF 4.3 3区 生物学
Human Cell Pub Date : 2022-05-18 DOI: 10.1007/s13577-022-00707-3
Xiaofeng Han, Jie Chen
{"title":"KAT2A affects tumor metabolic reprogramming in colon cancer progression through epigenetic activation of E2F1","authors":"Xiaofeng Han, Jie Chen","doi":"10.1007/s13577-022-00707-3","DOIUrl":"https://doi.org/10.1007/s13577-022-00707-3","url":null,"abstract":"","PeriodicalId":13228,"journal":{"name":"Human Cell","volume":"35 1","pages":"1140 - 1158"},"PeriodicalIF":4.3,"publicationDate":"2022-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42273194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Construction and comprehensive analysis of a lncRNA–mRNA interactive network to reveal a potential lncRNA for hepatic encephalopathy development lncRNA - mrna相互作用网络的构建和综合分析，揭示肝性脑病发展的潜在lncRNA
IF 4.3 3区 生物学
Human Cell Pub Date : 2022-05-18 DOI: 10.1007/s13577-022-00714-4
Chihao Zhang, Wei Ni, Yiming Zhu, Jia-Yun Lin, Hongjie Li, Zhifeng Zhao, Ke Wang, Haizhong Huo, Meng Luo
{"title":"Construction and comprehensive analysis of a lncRNA–mRNA interactive network to reveal a potential lncRNA for hepatic encephalopathy development","authors":"Chihao Zhang, Wei Ni, Yiming Zhu, Jia-Yun Lin, Hongjie Li, Zhifeng Zhao, Ke Wang, Haizhong Huo, Meng Luo","doi":"10.1007/s13577-022-00714-4","DOIUrl":"https://doi.org/10.1007/s13577-022-00714-4","url":null,"abstract":"","PeriodicalId":13228,"journal":{"name":"Human Cell","volume":"35 1","pages":"1060 - 1070"},"PeriodicalIF":4.3,"publicationDate":"2022-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48460934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
The inhibitory effects of Dulaglutide on cellular senescence against high glucose in human retinal endothelial cells 杜拉鲁肽对人视网膜内皮细胞高糖衰老的抑制作用
IF 4.3 3区 生物学
Human Cell Pub Date : 2022-05-18 DOI: 10.1007/s13577-022-00703-7
S. Nian, Yajing Mi, Kai Ren, S. Wang, Mingkai Li, Di Yang
{"title":"The inhibitory effects of Dulaglutide on cellular senescence against high glucose in human retinal endothelial cells","authors":"S. Nian, Yajing Mi, Kai Ren, S. Wang, Mingkai Li, Di Yang","doi":"10.1007/s13577-022-00703-7","DOIUrl":"https://doi.org/10.1007/s13577-022-00703-7","url":null,"abstract":"","PeriodicalId":13228,"journal":{"name":"Human Cell","volume":"35 1","pages":"995 - 1004"},"PeriodicalIF":4.3,"publicationDate":"2022-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46378714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
In memoriam: Yoshihiro Kikuchi (1939–2022) 纪念：菊池义弘（1939–2022）
IF 4.3 3区 生物学
Human Cell Pub Date : 2022-05-16 DOI: 10.1007/s13577-022-00722-4
N. Shinomiya, Tsunekazu Kita, H. Kataoka
{"title":"In memoriam: Yoshihiro Kikuchi (1939–2022)","authors":"N. Shinomiya, Tsunekazu Kita, H. Kataoka","doi":"10.1007/s13577-022-00722-4","DOIUrl":"https://doi.org/10.1007/s13577-022-00722-4","url":null,"abstract":"","PeriodicalId":13228,"journal":{"name":"Human Cell","volume":"35 1","pages":"955 - 956"},"PeriodicalIF":4.3,"publicationDate":"2022-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49256502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Serum-derived extracellular vesicles mediate Smad4 expression through shuttling microRNA-27a in the progression of laryngeal squamous cell carcinoma 在喉癌的发展过程中，血清源性细胞外囊泡通过穿梭microRNA-27a介导Smad4表达
IF 4.3 3区 生物学
Human Cell Pub Date : 2022-05-12 DOI: 10.1007/s13577-022-00712-6
Y. Shuang, Xiao-feng Yao, Jing Liu, J. Niu, Wenyu Guo, Chao Li
{"title":"Serum-derived extracellular vesicles mediate Smad4 expression through shuttling microRNA-27a in the progression of laryngeal squamous cell carcinoma","authors":"Y. Shuang, Xiao-feng Yao, Jing Liu, J. Niu, Wenyu Guo, Chao Li","doi":"10.1007/s13577-022-00712-6","DOIUrl":"https://doi.org/10.1007/s13577-022-00712-6","url":null,"abstract":"","PeriodicalId":13228,"journal":{"name":"Human Cell","volume":"35 1","pages":"1084 - 1099"},"PeriodicalIF":4.3,"publicationDate":"2022-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43447338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
STK11 overexpression prevents glucocorticoid-induced osteoporosis via activating the AMPK/SIRT1/PGC1α axis STK11过表达通过激活AMPK/SIRT1/PGC1α轴阻止糖皮质激素诱导的骨质疏松症
IF 4.3 3区 生物学
Human Cell Pub Date : 2022-05-11 DOI: 10.1007/s13577-022-00704-6
Jiao Xiao, Wenjin Li, Guojuan Li, Jiankai Tan, Na Dong
{"title":"STK11 overexpression prevents glucocorticoid-induced osteoporosis via activating the AMPK/SIRT1/PGC1α axis","authors":"Jiao Xiao, Wenjin Li, Guojuan Li, Jiankai Tan, Na Dong","doi":"10.1007/s13577-022-00704-6","DOIUrl":"https://doi.org/10.1007/s13577-022-00704-6","url":null,"abstract":"","PeriodicalId":13228,"journal":{"name":"Human Cell","volume":"35 1","pages":"1045 - 1059"},"PeriodicalIF":4.3,"publicationDate":"2022-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42115023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Regulation of osteogenic differentiation by the pro-inflammatory cytokines IL-1β and TNF-α: current conclusions and controversies 促炎因子IL-1β和TNF-α对成骨分化的调控:目前的结论和争议
IF 4.3 3区 生物学
Human Cell Pub Date : 2022-05-06 DOI: 10.1007/s13577-022-00711-7
Qingyun Mo, Wei Zhang, Aijing Zhu, L. Backman, Jialin Chen
{"title":"Regulation of osteogenic differentiation by the pro-inflammatory cytokines IL-1β and TNF-α: current conclusions and controversies","authors":"Qingyun Mo, Wei Zhang, Aijing Zhu, L. Backman, Jialin Chen","doi":"10.1007/s13577-022-00711-7","DOIUrl":"https://doi.org/10.1007/s13577-022-00711-7","url":null,"abstract":"","PeriodicalId":13228,"journal":{"name":"Human Cell","volume":"35 1","pages":"957 - 971"},"PeriodicalIF":4.3,"publicationDate":"2022-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42369510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
Factors influencing mesenchymal stromal cells in in vitro cellular models to study retinal pigment epithelial cell rescue 间充质细胞的影响因素在体外细胞模型中研究视网膜色素上皮细胞的抢救作用
IF 4.3 3区 生物学
Human Cell Pub Date : 2022-05-05 DOI: 10.1007/s13577-022-00705-5
Girish K Srivastava, David Rodriguez-Crespo, Iván Fernández-Bueno, J. Pastor
{"title":"Factors influencing mesenchymal stromal cells in in vitro cellular models to study retinal pigment epithelial cell rescue","authors":"Girish K Srivastava, David Rodriguez-Crespo, Iván Fernández-Bueno, J. Pastor","doi":"10.1007/s13577-022-00705-5","DOIUrl":"https://doi.org/10.1007/s13577-022-00705-5","url":null,"abstract":"","PeriodicalId":13228,"journal":{"name":"Human Cell","volume":"35 1","pages":"1005 - 1015"},"PeriodicalIF":4.3,"publicationDate":"2022-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47223689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long non-coding RNA linc00921 suppresses tumorigenesis and epithelial-to-mesenchymal transition of triple-negative breast cancer via targeting miR-9-5p/LZTS2 axis. 长链非编码RNA linc00921通过靶向miR-9-5p/LZTS2轴抑制三阴性乳腺癌的肿瘤发生和上皮-间质转化。
IF 4.3 3区 生物学
Human Cell Pub Date : 2022-05-01 Epub Date: 2022-02-18 DOI: 10.1007/s13577-022-00685-6
Jie Zhang, Lina Zhang, Jianlong Wang, Jing Zhao, Xuelian Zhao, Chunli Zhang, Peng Han, Cuizhi Geng
{"title":"Long non-coding RNA linc00921 suppresses tumorigenesis and epithelial-to-mesenchymal transition of triple-negative breast cancer via targeting miR-9-5p/LZTS2 axis.","authors":"Jie Zhang,&nbsp;Lina Zhang,&nbsp;Jianlong Wang,&nbsp;Jing Zhao,&nbsp;Xuelian Zhao,&nbsp;Chunli Zhang,&nbsp;Peng Han,&nbsp;Cuizhi Geng","doi":"10.1007/s13577-022-00685-6","DOIUrl":"https://doi.org/10.1007/s13577-022-00685-6","url":null,"abstract":"<p><p>Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer. Dysregulation of long non-coding RNAs (lncRNAs) plays crucial roles in the initiation and progression of TNBC. In this study, we analyzed public GEO profiles to verify the key lncRNAs in TNBC. Linc00921 was selected for further study. Low expression of linc00921 was observed in 49 of 95 TNBC tissues. Low expression of linc00921 was correlated with poor postoperative disease-free survival (DFS) and overall survival (OS) of TNBC patients. Overexpression of linc00921 with lentivirus suppressed the proliferation, migration and invasion of TNBC cells. A luciferase reporter assay showed that linc00921 could sponge miR-9-5p in TNBC. Moreover, linc00921 and miR-9-5p occupied the same Argonaute-2 (Ago2) protein in TNBC cells. Leucine zipper tumor suppressor 2 (LZTS2) was recognized as a target gene of miR-9-5p, and thereby a linc00921/miR-9-5p/LZTS2 axis was identified in TNBC cells. Overexpression of linc00921 promoted nuclear export of β-catenin, neutralized its function, and subsequently promoted epithelial-to-mesenchymal transition (EMT) in TNBC. A xenograft tumor mouse model showed that the miR-9-5p inhibitor upregulates LZTS2 expression and induce nuclear export of β-catenin in TNBC. Thus, linc00921 upregulates LZTS2 by sponging miR-9-5p to suppress tumorigenesis and EMT of TNBC. Linc00921/miR-9-5p/LZTS2 axis may be a novel biomarker and therapeutic target for TNBC patients.</p>","PeriodicalId":13228,"journal":{"name":"Human Cell","volume":"35 3","pages":"909-923"},"PeriodicalIF":4.3,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9013323/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39934636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
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