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ARTIFICIAL INTELLIGENCE TECHNOLOGIES FOR MORPHOLOGY: OPPORTUNITIES AND PROSPECTS 形态学的人工智能技术:机遇与前景
http://eng.biomos.ru/conference/articles.htm Pub Date : 2021-01-01 DOI: 10.37747/10.37747/2312-640x-2021-19-155-158
E.I. Ivanova, V.O. Grinin, A. Bakulina, P. S. Timashev
{"title":"ARTIFICIAL INTELLIGENCE TECHNOLOGIES FOR MORPHOLOGY: OPPORTUNITIES AND PROSPECTS","authors":"E.I. Ivanova, V.O. Grinin, A. Bakulina, P. S. Timashev","doi":"10.37747/10.37747/2312-640x-2021-19-155-158","DOIUrl":"https://doi.org/10.37747/10.37747/2312-640x-2021-19-155-158","url":null,"abstract":"In this work, a program was developed based on U-Net and VGG neural network architectures for segmentation and analysis of scan images of kidney and colon tissues. The program maps up to 12 classes of anatomical structures in tissues, and also allows the calculation of predictive histological biomarkers to support physician decision-making.","PeriodicalId":13077,"journal":{"name":"http://eng.biomos.ru/conference/articles.htm","volume":"43 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79928499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
MONITORING OF BIOLOGICAL ACTIVITY OF BETA-LACTAM ANTIBIOTICS RECEPTOR BLAR-CTD IN THE PROCESSES OF ITS HETEROLOGICAL EXPRESSION, PURIFICATION AND APPLICATION IN ANALYTICAL SYSTEMS β -内酰胺类抗生素受体blar-ctd异源表达、纯化及分析系统应用过程中的生物活性监测
http://eng.biomos.ru/conference/articles.htm Pub Date : 2021-01-01 DOI: 10.37747/2312-640x-2021-19-246-248
P. Semizhon, H.P. Scheslenok, I. V. Harbachova, I. Vashkevich, O. Sviridov
{"title":"MONITORING OF BIOLOGICAL ACTIVITY OF BETA-LACTAM ANTIBIOTICS RECEPTOR BLAR-CTD IN THE PROCESSES OF ITS HETEROLOGICAL EXPRESSION, PURIFICATION AND APPLICATION IN ANALYTICAL SYSTEMS","authors":"P. Semizhon, H.P. Scheslenok, I. V. Harbachova, I. Vashkevich, O. Sviridov","doi":"10.37747/2312-640x-2021-19-246-248","DOIUrl":"https://doi.org/10.37747/2312-640x-2021-19-246-248","url":null,"abstract":"To develop the technologies of beta-lactam antibiotics bioassays in foods, high purity beta-lactam receptor BlaR-CTD has been obtained and characterized. A test system for the quantitation of the biologically active and immunoreactive receptor in the processes of its heterological expression, isolation and reagent forms preparation was elaborated. The immunochemical properties and antibiotic binding ability of BlaR-CTD were investigated, and the constructions and application procedures of receptor-immune systems for the assay of beta-lactam antibiotics using microplates or chromatographic test-strips were proposed.","PeriodicalId":13077,"journal":{"name":"http://eng.biomos.ru/conference/articles.htm","volume":"152 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91493108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
IMPLANTED MATERIALS BASED ON MODIFIED PECTINS FOR BIOENGINEERING NERVE TISSUE RECONSTRUCTION 基于改性果胶的植入材料用于生物工程神经组织重建
http://eng.biomos.ru/conference/articles.htm Pub Date : 2021-01-01 DOI: 10.37747/2312-640x-2021-19-18-20
N. Shved, O.Yu. Kuzyakova, A.V. Vitkalova, V. Kovalev, G. Malykin, I. Dyuizen, V. V. Kumeiko
{"title":"IMPLANTED MATERIALS BASED ON MODIFIED PECTINS FOR BIOENGINEERING NERVE TISSUE RECONSTRUCTION","authors":"N. Shved, O.Yu. Kuzyakova, A.V. Vitkalova, V. Kovalev, G. Malykin, I. Dyuizen, V. V. Kumeiko","doi":"10.37747/2312-640x-2021-19-18-20","DOIUrl":"https://doi.org/10.37747/2312-640x-2021-19-18-20","url":null,"abstract":"The structure and properties of implanted materials based on modified pectins have been investigated, and the proposed mechanism of their action on the cells of the nervous tissue has been shown.","PeriodicalId":13077,"journal":{"name":"http://eng.biomos.ru/conference/articles.htm","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91339710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
MAGNETIC NANOCOMPOSITES IN PIEZOELECTRIC SENSORS FOR DETERMINATION OF GLYPHOSATE 磁性纳米复合材料在压电传感器中测定草甘膦
http://eng.biomos.ru/conference/articles.htm Pub Date : 2021-01-01 DOI: 10.37747/2312-640x-2021-19-383-385
D.M. Smolyaninova, E. V. Bizina, M. Larina, T. Ermolaeva
{"title":"MAGNETIC NANOCOMPOSITES IN PIEZOELECTRIC SENSORS FOR DETERMINATION OF GLYPHOSATE","authors":"D.M. Smolyaninova, E. V. Bizina, M. Larina, T. Ermolaeva","doi":"10.37747/2312-640x-2021-19-383-385","DOIUrl":"https://doi.org/10.37747/2312-640x-2021-19-383-385","url":null,"abstract":"Piezoelectric gravimetric sensors based on magnetic nanocomposites: polymers with molecular imprints (MIP) Fe3O4@MIP N - (phosphonmethyl) - glycine have been developed. It was found that the optimal concentration ratio of template: functional monomer: cross-monomer is 1: 3: 25. The best synthesis time is 3h with constant stirring at a speed of 60 rpm and heating to 60 °C.","PeriodicalId":13077,"journal":{"name":"http://eng.biomos.ru/conference/articles.htm","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73354264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
DEOXYURIDINE TRIPHOSPHATES MODIFIED WITH AROMATIC TYROSINE GROUPS FOR ELECTROCHEMICAL DETERMINATION OF RECOMBINASE POLYMERASE AMPLIFICATION PRODUCTS OF DNA 芳香酪氨酸修饰的三磷酸脱氧尿嘧啶电化学测定DNA重组酶扩增产物
http://eng.biomos.ru/conference/articles.htm Pub Date : 2021-01-01 DOI: 10.37747/2312-640x-2021-19-236-238
G. Kutdusova, E. Suprun
{"title":"DEOXYURIDINE TRIPHOSPHATES MODIFIED WITH AROMATIC TYROSINE GROUPS FOR ELECTROCHEMICAL DETERMINATION OF RECOMBINASE POLYMERASE AMPLIFICATION PRODUCTS OF DNA","authors":"G. Kutdusova, E. Suprun","doi":"10.37747/2312-640x-2021-19-236-238","DOIUrl":"https://doi.org/10.37747/2312-640x-2021-19-236-238","url":null,"abstract":"Deoxyuridine triphosphates modified with tyrosine or tryptophan aromatic groups were tested as electroactive ‘labels’ for the electrochemical detection of double-stranded DNA amplicons obtained by recombinase polymerase amplification.","PeriodicalId":13077,"journal":{"name":"http://eng.biomos.ru/conference/articles.htm","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80155478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
ANTIMICROBIAL FILM COATING BASED ON ENZYMATICALLY SYNTHESIZED POLYANILINE DOPED WITH COPPER IONS 酶促合成掺杂铜离子的聚苯胺抗菌膜涂层
http://eng.biomos.ru/conference/articles.htm Pub Date : 2021-01-01 DOI: 10.37747/2312-640x-2021-19-29-31
M. Khlupova, G. Shumakovich, E. Zaitseva, E. Gromova, O. Morozova
{"title":"ANTIMICROBIAL FILM COATING BASED ON ENZYMATICALLY SYNTHESIZED POLYANILINE DOPED WITH COPPER IONS","authors":"M. Khlupova, G. Shumakovich, E. Zaitseva, E. Gromova, O. Morozova","doi":"10.37747/2312-640x-2021-19-29-31","DOIUrl":"https://doi.org/10.37747/2312-640x-2021-19-29-31","url":null,"abstract":"Enzymatic synthesis of polyaniline (PANI) doped with bivalent copper ions was carried out on a sodium polystyrene sulfonate (PSS) template. The synthesized interpolymer complex PANI-Cu2+/PSS had an inhibitory effect on the growth of Staphylococcus aureus and Escherichia coli cells.","PeriodicalId":13077,"journal":{"name":"http://eng.biomos.ru/conference/articles.htm","volume":"40 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81478874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
MOLECULAR MARKERS FOR CANCER DIAGNOSIS AND THERAPY 用于癌症诊断和治疗的分子标记
http://eng.biomos.ru/conference/articles.htm Pub Date : 2021-01-01 DOI: 10.37747/2312-640x-2021-19-142-144
V. Skripova, L. Bulatova, D. Savenkova, A. K. Nurgalieva, R. Vlasenkova, D. Reshetnikova, A. Timonina, M. Bogdanov
{"title":"MOLECULAR MARKERS FOR CANCER DIAGNOSIS AND THERAPY","authors":"V. Skripova, L. Bulatova, D. Savenkova, A. K. Nurgalieva, R. Vlasenkova, D. Reshetnikova, A. Timonina, M. Bogdanov","doi":"10.37747/2312-640x-2021-19-142-144","DOIUrl":"https://doi.org/10.37747/2312-640x-2021-19-142-144","url":null,"abstract":"Using CRISPR/Cas9 and SEREX technologies we have identified and characterized more than two hundred potential molecular markers of oncological diseases. It was shown that the sodium-dependent phosphate transporter NaPi2b is a unique target for the development of antitumor targeted drugs due to its localization and tumor-specific epitope.","PeriodicalId":13077,"journal":{"name":"http://eng.biomos.ru/conference/articles.htm","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82579207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
HIGHLY SENSITIVE METHODS FOR MICRORNA DETECTION USING ISOTHERMAL METHODS FOR NUCLEIC ACIDS AMPLIFICATION 采用等温法进行核酸扩增的高灵敏度微rna检测方法
http://eng.biomos.ru/conference/articles.htm Pub Date : 2021-01-01 DOI: 10.37747/2312-640x-2021-19-244-246
O. Bodulev, A. Soloviev
{"title":"HIGHLY SENSITIVE METHODS FOR MICRORNA DETECTION USING ISOTHERMAL METHODS FOR NUCLEIC ACIDS AMPLIFICATION","authors":"O. Bodulev, A. Soloviev","doi":"10.37747/2312-640x-2021-19-244-246","DOIUrl":"https://doi.org/10.37747/2312-640x-2021-19-244-246","url":null,"abstract":"This work will present the results of the development of two new highly sensitive heterogeneous methods for the determination of miRNA-141 and miRNA-39 using the isothermal circular strand-displacement amplification and the catalytic hairpin assembly methods for analyte amplification.","PeriodicalId":13077,"journal":{"name":"http://eng.biomos.ru/conference/articles.htm","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80879557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
EFFECT OF MUTATIONS IN THE REGULATORY REGION OF OPERON ILVBNC ON EXPRESSION OF OPERON GENES, ACTIVITY OF THE ENZYME AHAS AND PRODUCTION OF L-VALINE IN CORYNEBACTERIUM GLUTAMICUM STRAINS 操纵子ilvbnc调控区突变对谷氨酸棒状杆菌操纵子基因表达、酶活性和l -缬氨酸产生的影响
http://eng.biomos.ru/conference/articles.htm Pub Date : 2021-01-01 DOI: 10.37747/2312-640x-2021-19-316-317
T. Leonova, T. I. Kalinina, T. V. Gerasimova, I. Titov, A. Yanenko
{"title":"EFFECT OF MUTATIONS IN THE REGULATORY REGION OF OPERON ILVBNC ON EXPRESSION OF OPERON GENES, ACTIVITY OF THE ENZYME AHAS AND PRODUCTION OF L-VALINE IN CORYNEBACTERIUM GLUTAMICUM STRAINS","authors":"T. Leonova, T. I. Kalinina, T. V. Gerasimova, I. Titov, A. Yanenko","doi":"10.37747/2312-640x-2021-19-316-317","DOIUrl":"https://doi.org/10.37747/2312-640x-2021-19-316-317","url":null,"abstract":"A point mutation in the regulatory region of the ilvBNC operon leads to an increase in the transcription of the operon genes, an increase in the activity of the AHAS enzyme, and an increase in the synthesis of L-valine.","PeriodicalId":13077,"journal":{"name":"http://eng.biomos.ru/conference/articles.htm","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87151263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
SUPERCRITICAL EXTRACTION FOR THE ISOLATION OF BIOLOGICALLY ACTIVE SUBSTANCES 超临界萃取分离生物活性物质
http://eng.biomos.ru/conference/articles.htm Pub Date : 2021-01-01 DOI: 10.37747/2312-640x-2021-19-185-187
I. V. Kazeev, I. Khudeev, O. Bocharova
{"title":"SUPERCRITICAL EXTRACTION FOR THE ISOLATION OF BIOLOGICALLY ACTIVE SUBSTANCES","authors":"I. V. Kazeev, I. Khudeev, O. Bocharova","doi":"10.37747/2312-640x-2021-19-185-187","DOIUrl":"https://doi.org/10.37747/2312-640x-2021-19-185-187","url":null,"abstract":"The paper presents the developing direction of supercritical extraction (SCE), which opens up new prospects for the extraction of biologically active substances from plant raw materials. Research is underway to obtain active biological substances for the treatment of socially significant diseases.","PeriodicalId":13077,"journal":{"name":"http://eng.biomos.ru/conference/articles.htm","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87800530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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