Hormones最新文献_第6页

Sarcoidosis of the hypothalamus. A case report with a review of the literature. 下丘脑结节病。一份病例报告及文献回顾。

Hormones Pub Date : 1971-01-01

A Heffernan, M Cullen, R Towers, D K O'Donovan

引用次数: 0

Radioimmunoassay of a human pituitary prolactin in plasma. 血浆中人垂体催乳素的放射免疫测定。

Hormones Pub Date : 1971-01-01 DOI: 10.1159/000178230

G D Bryant, T M Siler, F C Greenwood, J L Pasteels, C Robyn, P O Hubinont

{"title":"Radioimmunoassay of a human pituitary prolactin in plasma.","authors":"G D Bryant, T M Siler, F C Greenwood, J L Pasteels, C Robyn, P O Hubinont","doi":"10.1159/000178230","DOIUrl":"https://doi.org/10.1159/000178230","url":null,"abstract":"A protein fraction with prolactin bioactivities was obtained from the culture medium of human fetal pituitary tissue in long term cultures and termed Pasteels human prolactin (PHP) for convenience. An antiserum was prepared against this human prolactin and used to develop a radioimmunoassay for the material in human plasma. The antigen available (220 µg)was tested against antisera to human growth hormone and to human placental lactogen and in radioimmunoassays for these hormones. The results suggested that the human prolactin fraction contained some immunoreactive human growth hormone (1%). The resulting antibodies in the antihuman prolactin serum could be neutralized by the addition of human growth hormone. The human prolactin also generated antibodies, binding 131I-labelled human prolactin, which were not neutralized by human growth hormone. This binding was inhibited by plasma from a normal male, 2 normal females and by plasma from a lactating woman after breast feeding. An increase in plasma concentration of the inhibitor, immunologically similar to the human prolactin fraction, was obtained after phenothiazine injection. In the 7 plasma samples tested for human prolactin only 1 contained a detectable concentration of immunoreactive growth hormone. Immunoreactive human placental lactogen (human chorionic somatomammotropin) or any material cross-reacting with anti-HCS serum was undetectable in these plasma samples by a sensitive radioimmunoassay. It is suggested that human plasmas contain detectable amounts of a material immunologically similar to a prolactin fraction isolated from tissue cultures of fetal pituitaries. The fraction and the plasma inhibitor are distinguishable by immunoassay from human growth hormone and from human placental lactogen.","PeriodicalId":13017,"journal":{"name":"Hormones","volume":"2 3","pages":"139-52"},"PeriodicalIF":0.0,"publicationDate":"1971-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000178230","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"16096617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 21

The measurement of progesterone in human plasma by competitive protein-binding radioassay. 竞争性蛋白结合放射法测定人血浆中黄体酮。

Hormones Pub Date : 1971-01-01 DOI: 10.1159/000178231

C Fassorra, M Luisi

引用次数: 5

Serum tests for measurement of thyroid function. 测定甲状腺功能的血清试验。

Hormones Pub Date : 1971-01-01 DOI: 10.1159/000178240

N I Robin, S R Hagen, F Collaço, S Refetoff, H A Selenkow

引用次数: 64

Effect of chlorpropamide and water deprivation on free water clearance in patients with diabetes insipidus. 氯丙胺联合水剥夺对尿崩症患者游离水清除的影响。

Hormones Pub Date : 1971-01-01 DOI: 10.1159/000178248

M L Batrinos, G J Tolis, G Traïanos

引用次数: 1

Reproduction in human high altitude populations. 人类在高海拔地区的繁殖。

Hormones Pub Date : 1971-01-01 DOI: 10.1159/000178221

E J Clegg, G A Harrison

引用次数: 10

In vitro plasma inactivation of thyrotropin releasing factor (TRF) and related peptides. Its inhibition by various means and by the synthetic dipeptide PCA-His-OME. 促甲状腺激素释放因子(TRF)及相关肽的体外血浆失活。其抑制作用可通过多种途径及合成二肽PCA-His-OME实现。

Hormones Pub Date : 1971-01-01 DOI: 10.1159/000178234

W W Vale, R Burgus, T F Dunn, R Guillemin

引用次数: 42

Experience with insulin-induced hypoglycemia as a provocative test for growth hormone and cortisol secretion in children. 胰岛素诱导的低血糖作为儿童生长激素和皮质醇分泌的刺激试验的经验。

Hormones Pub Date : 1971-01-01 DOI: 10.1159/000178247

J Girard, J B Baumann, M Stahl, P W Nars, U Bühler, H Wick

{"title":"Experience with insulin-induced hypoglycemia as a provocative test for growth hormone and cortisol secretion in children.","authors":"J Girard, J B Baumann, M Stahl, P W Nars, U Bühler, H Wick","doi":"10.1159/000178247","DOIUrl":"https://doi.org/10.1159/000178247","url":null,"abstract":"Insulin-induced hypoglycemia has been used in 109 children with a variety of disorders to assess the hypothalamo-pituitary adrenal axis.The patients were divided into 3 groups: (1) patients with growth retardation and with various disorders where an involvement of the hypothalamo-pituitary region was suspected; (2) obese patients; (3) specific syndromes: spontaneous hypoglycemia, anorexia nervosa, Turner’s syndrome, craniopharyngioma. Glucose, free fatty acids, cortisol and growth hormone were measured before injection of insulin, and at 20-min-intervals thereafter for a period of 2–4 h. The findings, particularly in obesity and in syndromes other than growth disorders have shown, that a series of factors have to be considered for a correct interpretation of the hormonal response to hypoglycemia. The limits for normal, reduced or absent response are given and as a simple screening for growth hormonee deficiency, a growth hormone estimation without stimulation can be used. The test has been found safe under clinical conditions and to provide reliable information about growth hormone and ACTH, respectively cortisol reaction.","PeriodicalId":13017,"journal":{"name":"Hormones","volume":"2 6","pages":"338-65"},"PeriodicalIF":0.0,"publicationDate":"1971-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000178247","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"16096631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 12

Further contribution to the understanding of the post-infarctual anedematous syndrome. 进一步有助于理解梗死后水肿综合征。

Hormones Pub Date : 1971-01-01 DOI: 10.1159/000178227

A Lodi, P Bernardi, G C Descovich, F M Gritti

引用次数: 1

The analysis of the endometrium of 1,000 sterile women. 1000名不孕妇女子宫内膜分析。

Hormones Pub Date : 1971-01-01 DOI: 10.1159/000178225

G Silló-Seidl

引用次数: 14