{"title":"促甲状腺激素释放因子(TRF)及相关肽的体外血浆失活。其抑制作用可通过多种途径及合成二肽PCA-His-OME实现。","authors":"W W Vale, R Burgus, T F Dunn, R Guillemin","doi":"10.1159/000178234","DOIUrl":null,"url":null,"abstract":"Incubation in vitro of natural (ovine) or synthetic TRF (PCA-His-Pro-NH2) with rat blood, plasma, or reconstituted lyophilized serum destroys the biological activity. Ina","PeriodicalId":13017,"journal":{"name":"Hormones","volume":"2 4","pages":"193-203"},"PeriodicalIF":0.0000,"publicationDate":"1971-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000178234","citationCount":"42","resultStr":"{\"title\":\"In vitro plasma inactivation of thyrotropin releasing factor (TRF) and related peptides. Its inhibition by various means and by the synthetic dipeptide PCA-His-OME.\",\"authors\":\"W W Vale, R Burgus, T F Dunn, R Guillemin\",\"doi\":\"10.1159/000178234\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Incubation in vitro of natural (ovine) or synthetic TRF (PCA-His-Pro-NH2) with rat blood, plasma, or reconstituted lyophilized serum destroys the biological activity. Ina\",\"PeriodicalId\":13017,\"journal\":{\"name\":\"Hormones\",\"volume\":\"2 4\",\"pages\":\"193-203\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1971-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1159/000178234\",\"citationCount\":\"42\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Hormones\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1159/000178234\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Hormones","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1159/000178234","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
In vitro plasma inactivation of thyrotropin releasing factor (TRF) and related peptides. Its inhibition by various means and by the synthetic dipeptide PCA-His-OME.
Incubation in vitro of natural (ovine) or synthetic TRF (PCA-His-Pro-NH2) with rat blood, plasma, or reconstituted lyophilized serum destroys the biological activity. Ina
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