Herba Polonica最新文献

{"title":"Optimization of microwave-assisted extraction of phenolic compounds from ginger (Zingiber officinale Rosc.) using response surface methodology","authors":"T. Huyen, L. Quoc","doi":"10.2478/hepo-2020-0007","DOIUrl":"https://doi.org/10.2478/hepo-2020-0007","url":null,"abstract":"Summary Introduction: Ginger (Zingiber officinale Rosc.) is a common spice and precious herbal plant in Vietnam. It contains many bioactive compounds, especially phenolic compounds useful for human health. Hence, the extraction and application of these compounds in medical technology are necessary. Objective: The goal of this study is to determine the optimal extraction conditions with the assistance of microwave, for instance solvent/material ratio (ml/g), solvent concentration (%, v/v) and extraction time, on the extraction yield of ginger rhizome, such as total polyphenol content (TPC) and antioxidant capacity (AC). Methods: The dried sample was extracted by microwave-assisted extraction (MAE). TPC and AC of received extract were measured by the Folin-Ciocalteu method and phenanthroline assay. The optimization process used response surface methodology (RSM) (Central composite face design, CCF) with major influencing factors including solvent concentration, solvent/material ratio and extraction time. Results: The results showed that the optimal extraction conditions were the ethanol concentration of 60%, ethanol/material ratio of 48.6/1 (ml/g), extraction time of 1 minute. Conclusion: The maximum TPC and AC peaked at 27.89±1.99 mg GAE/g dry matter and 12.24±0.04 mmol Fe/g dry matter (DM) at optimal extraction conditions. Besides, some factors strongly affected the extraction yield and interacted together.","PeriodicalId":12990,"journal":{"name":"Herba Polonica","volume":"66 1","pages":"19 - 27"},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46142037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"HPLC-DAD-ESI/MS comparison of the chemical composition of flowers from two Arnica species grown in Poland","authors":"Katarzyna Kimel, M. Krauze-Baranowska, Sylwia Godlewska, L. Pobłocka-Olech","doi":"10.2478/hepo-2020-0008","DOIUrl":"https://doi.org/10.2478/hepo-2020-0008","url":null,"abstract":"Summary Introduction: Arnica flowers are used in pharmaceutical and cosmetic industry. According to EMA only endangered Arnica montana provides the medicinal plant material. However, some European countries also allow the use of A. chamissonis flowers, whose chemical composition is not known in detail. Objective: The aim of the study was to recognize and compare the chemical composition of A. montana and A. chamissonis flowers collected from plants cultivated in Poland. Methods: HPLC-DAD-ESI/MS analysis comprised phenolic acids, flavonoids and sesquiterpene lactones. Results: Thirty eight flavonoids and phenolic acids were recognized and quantified, with patuletin, 6-methoxykaempferol and quercetin present only in A. chamissonis flowers. Moreover, helenalin and acetyl-dihydrohelenalin were identified. Conclusion: A. montana and A. chamissonis flowers from plants grown in Poland possess similar composition of simple phenols and polyphenols, present in concentration slightly higher in A. montana. Helenalin and dihydrohelenalin esters identified in arnica flowers from various regions of Europe were not detected.","PeriodicalId":12990,"journal":{"name":"Herba Polonica","volume":"66 1","pages":"1 - 10"},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47165124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Developmental and chemical characteristics of Melittis melissophyllum L. in limited access of sunlight","authors":"Izabela Szymborska-Sandhu","doi":"10.2478/hepo-2020-0003","DOIUrl":"https://doi.org/10.2478/hepo-2020-0003","url":null,"abstract":"Summary Introduction: Bastard balm grows in forests, in central and southeastern part of Europe. The herb of this species is rich in phenolics, mainly flavonoids, phenolic acids and coumarins. The plant is used in traditional European medicine, in digestive problems and for aromatizing tobacco and alcohol products. Objective: The purpose of this study was to determine the influence of shading on bastard balm development and the accumulation of phenolics in its herb, with special respect to coumarin as a quality marker of this raw material. Methods: The plants were cultivated in full sunlight, in 30% and 50% shade provided by shading nets. The herb was harvested from plants in the third year of vegetation, at four subsequent developmental stages and then subjected to chemical evaluation. In the raw material, the total contents of flavonoids, phenolic acids and coumarins was determined. The content of coumarin was analyzed using HPLC-DAD. Results: Plants grown in 30% shade produced the highest number of flowers and seeds. They produced the highest mass of herb at the beginning of the seed-setting stage. The plants grown in full sunlight revealed the highest content of flavonoids and phenolic acids, especially during flowering and at the beginning of the seed-setting stage. The mass of herb obtained by plants cultivated at deep (50%) shade was the lowest, however, the content of coumarin in these plants was the highest. Conclusion: The influence of shade on bastard balm was expressed by the herb mass and coumarin content increment. The plants thrived best in 30% shade, both in terms of flowering abundance and the mass of herb, whereas those from 50% shade were the richest in coumarin.","PeriodicalId":12990,"journal":{"name":"Herba Polonica","volume":"66 1","pages":"1 - 8"},"PeriodicalIF":0.0,"publicationDate":"2020-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44525440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antioxidant status and hepato-protective role of Anchomanes difformis in streptozotocin-induced diabetes in male Wistar rats","authors":"T. Alabi, N. Brooks, O. Oguntibeju","doi":"10.2478/hepo-2020-0005","DOIUrl":"https://doi.org/10.2478/hepo-2020-0005","url":null,"abstract":"Summary Introduction: The liver is involved in the metabolism of xenobiotics and their metabolites and it is vulnerable to oxidative damage. Hyperglycaemia is highly implicated in the progression of diabetes mellitus, and adversely affects the liver. Though, conventional hypoglycaemic drugs may be effective in reducing blood glucose, they do not appear to be effective in attenuating the progression of diabetes and its complications. Objective: This study evaluated the ameliorative effects of Anchomanes difformis on hyperglycaemia and hepatic injuries in type 2 diabetes. Methods: Type 2 diabetes was induced in male Wistar rats with a single intraperitoneal injection of streptozotocin (40 mg/kg BW) after two weeks of fructose (10%) administration. Aqueous extract of A. difformis (200 and 400 mg/kg BW) and glibenclamide (5 mg/kg BW) were administered orally for six weeks. Blood glucose concentrations were measured. Serum levels of liver dysfunction markers (ALT, AST, and ALP), total cholesterol, triglycerides, HDL- and LDL-cholesterol were investigated. Total protein, albumin, and globulin were also assessed. Antioxidant parameters: ORAC, GSH, GSSG, SOD, CAT and FRAP were evaluated in the liver while ORAC, FRAP and lipid peroxidation were determined in the serum. Histological examination of the liver tissue was carried out. Results: Treatment with aqueous extract of A. difformis significantly (p<0.05) reduced blood glucose and reversed steatosis in the diabetic-treated rats. The antioxidant status of diabetic-treated rats was significantly (p<0.05) improved. Serum levels of liver dysfunction markers were significantly (p<0.05) reduced in diabetic-treated rats. Conclusion: The findings in this study revealed that 400 mg/kgBW Anchomanes difformis was more effective than 200 mg/kg BW in ameliorating diabetes-induced hepatopathy, however, both doses of Anchomanes difformis demonstrated more antidiabetic ability than glibenclamide. Anchomanes difformis may be a novel and potential therapeutic agent in the management of diabetes and resulted hepatic injuries.","PeriodicalId":12990,"journal":{"name":"Herba Polonica","volume":"66 1","pages":"18 - 36"},"PeriodicalIF":0.0,"publicationDate":"2020-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45768527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research on polyphenols extraction from Polygonum multiflorum Thunb. roots","authors":"L. Quoc","doi":"10.2478/hepo-2020-0002","DOIUrl":"https://doi.org/10.2478/hepo-2020-0002","url":null,"abstract":"Summary Introduction: Polygonum multiflorum Thunb. is a herbal common plant in Asia, with many beneficial health effects for human because it contains many bioactive compounds which can prevent some diseases, for instance such as cardiovascular diseases, cancers, neurodegenerative diseases, etc. Objective: The purpose of this research is to point out the effects of extraction factors such as type of solvent, material/solvent ratio (w/v), solvent concentration (%, v/v), temperature (°C) and extraction time on the extraction yield of phenolic compounds from Polygonum multiflorum Thunb. roots, for instance, total polyphenol content (TPC) and antioxidant capacity (AC). Methods: The raw material consisting of Polygonum multiflorum Thunb root was extracted by the reflux maceration method. TPC and AC of received extract were evaluated by the Folin-Ciocalteu technique and DPPH method with Trolox as a standard agent. Results: The optimal conditions for the extraction process were acetone-water mixture (60%, v/v) as a solvent, material/solvent ratio of 1/40, extraction temperature of 50°C and extraction time of 90 minutes. The surface structure of material after extraction process changed insignificantly compared with the initial structure. Conclusion: The results showed that TPC and AC obtained the best values (38.60±0.56 mg GAE/g DW (dry weight) and 298.15±2.99 μmol TE/g DW, respectively) at optimal extraction conditions. In addition, some phenolic compounds were detected in the extract such as gallic acid, catechin and resveratrol.","PeriodicalId":12990,"journal":{"name":"Herba Polonica","volume":"66 1","pages":"9 - 17"},"PeriodicalIF":0.0,"publicationDate":"2020-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49194111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pharmacological properties of fireweed (Epilobium angustifolium L.) and bioavailability of ellagitannins. A review","authors":"M. Dreger, A. Adamczak, K. Seidler-Łożykowska, K. Wielgus","doi":"10.2478/hepo-2020-0001","DOIUrl":"https://doi.org/10.2478/hepo-2020-0001","url":null,"abstract":"Summary Fireweed (Epilobium angustifolium L.) is a well-known medicinal plant traditionally used in the treatment of urogenital diseases, stomach and liver disorders, skin problems, etc. E. angustifolium extracts show anti-androgenic, antiproliferative, cytotoxic, antioxidant, anti-inflammatory, immunomodulatory, and antimicrobial activities. The unique combination of biological properties demonstrated by the results of some studies indicates that fireweed has a positive effect in benign prostatic hyperplasia (BPH) and potentially in the prostate cancer chemoprevention. However, the efficacy of E. angustifolium phytotherapy is still poorly tested in clinical trials, while numerous beneficial effects of extracts have been documented in the in vitro and in vivo tests. Fireweed is rich in polyphenolic compounds, particularly ellagitannins. Currently, polyphenols are considered to be modulators of beneficial gut microbiota. The literature data support the use of ellagitannins in the prostate cancer chemoprevention, but caution is advised due to the highly variable production of urolithins by the individual microbiota. A better understanding of the microbiota’s role and the mechanisms of its action are crucial for an optimal therapeutic effect. This paper aims to summarize and discuss experimental data concerning pharmacological properties of E. angustifolium and bioavailability of ellagitannins – important bioactive compounds of this plant.","PeriodicalId":12990,"journal":{"name":"Herba Polonica","volume":"66 1","pages":"52 - 64"},"PeriodicalIF":0.0,"publicationDate":"2020-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42648218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ethnobotanical knowledge and folk medicinal significance of the flora of district Gujrat, Punjab, Pakistan","authors":"S. Ali, K. Hussain, K. Nawaz, K. Bhatti, Zobia Bashir, A. Nazeer, Usman Arif, Sana Jafar, E. H. Siddiqi","doi":"10.2478/hepo-2020-0004","DOIUrl":"https://doi.org/10.2478/hepo-2020-0004","url":null,"abstract":"Summary Introduction: Medicinal plants are the natural source of medicines used in treatment of many diseases among local communities of various countries. It is also the raw material for the pharmaceutical industry. Pakistan is a country with a variety of medicinal plants, comprehensively studied in some areas, while others still need more studies of their flora. Objectives: The study was performed to catalogue the flora of district Gujrat, Punjab, Pakistan and to assess its ethnomedicinal importance. Methods: A field survey was conducted in the Gujrat district (including Sarai Alamgir, Gujrat and Kharian) in 2019–2020 to collect the flora. Nearly 200 people of various age groups were interviewed and the questionnaire was filled, the gender and professions of the participants were also noted. Results: The plant species collected belonged to 32 different Angiosperm families i.e. Poaceae, Brassicaceae, Fabaceae, Asteraceae, Moraceae, Amaranthaceae, Apiaceae, Myrtaceae, Rutaceae, Solanaceae, Malvaceae, Euphorbiaceae and Lamiaceae. The obtained material consisted of 30 herbs, 20 shrubs and 22 trees. The floral parts used most often were leaves (63%) followed by: flower (41%), fruit (28%), stem (16%), seed (16%), bark (14%), root (13%), whole plant (12%), underground part (3%) and latex (3%). According to the study, the highest RFC (Relative Frequency of Citation) values were 0.1 in Cassia fistula L. (0.25) and the smallest RFC values were observed in Stellaria media (L.) Vill. – 0.025. The highest UV (Use Values) were noted for Achyranthes aspera L. at 0.9. In disease category, the highest value (0.67) of ICF (Informant Consensus Factor) was observed for stomach and skin infections, while the lowest ICF value was noted for diabetes and gonorrhoea (0.27). Conclusions: It was concluded that the Gujrat district is rich in useful plants that can be used in the preparation of various medicines as well as be sold on the herbal market.","PeriodicalId":12990,"journal":{"name":"Herba Polonica","volume":"66 1","pages":"37 - 51"},"PeriodicalIF":0.0,"publicationDate":"2020-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47511950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Traditional Chinese herb, Astragalus: possible for treatment and prevention of COVID-19?","authors":"Siu Kan Law, Chuiman Lo, Jie Han, Albert Wingnang Leung, Chuanshan Xu","doi":"10.2478/hepo-2020-0023","DOIUrl":"https://doi.org/10.2478/hepo-2020-0023","url":null,"abstract":"Astragalus is a traditional herb which has been used in China for a long time. It regulates blood circulation (vital energy), invigorates body fluid circulation, protects the flow of blood to fight against the attack of pathogens, and strengthens “blood deficiencies” according to Bencao Congxin. Astragalus was approved by the Food and Drug Administration in 2009 as a dietary supplement for upper respiratory infections, allergic rhinitis (hay fever), asthma, chronic fatigue syndrome, and chronic kidney disease. Thirty journals published in the past ten years were reviewed by using library search engines such as SCI/SCIE, PubMed, and Scopus. In this mini-review, we focus on the anti-inflammatory of Astragalus features, discuss the background of Astragalus and its function in various diseases from water-extracted Astragalus membranaceus, Astragalus saponins, and Astragalus polysaccharides. Based on the traditional Chinese medicine theory, Astragalus is a potential candidate to treat and prevent COVID-19.","PeriodicalId":12990,"journal":{"name":"Herba Polonica","volume":"66 1","pages":"79 - 84"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69210687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Variability of composition of essential oil and coumarin compounds of Angelica archangelica L.","authors":"A. Forycka, W. Buchwald","doi":"10.2478/hepo-2019-0027","DOIUrl":"https://doi.org/10.2478/hepo-2019-0027","url":null,"abstract":"Summary The medicinal and culinary properties of Angelica archangelica L. have been known and valued since the Middle Ages. Ingredients of essential oil and coumarins found in this plant are to a large degree responsible for its pharmacological activity. This study is a review of the literature of the most important biologically active compounds present in herbal raw materials: root (rhizome with roots) and angelica fruits. Research shows that the content of individual compounds of the essential oil and coumarin fraction is variable, which may point to a large intraspecific variation. Therefore, these compounds may be good markers for identifying taxa or chemotypes in chemotaxonomic research valuable for the herbal medicine and pharmaceutical industry.","PeriodicalId":12990,"journal":{"name":"Herba Polonica","volume":"65 1","pages":"62 - 75"},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47408468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Medicinal plants for management and alternative therapy of common ailments in Dutsin-Ma (Katsina State) in Nigeria","authors":"Idris Zubairu Sadiq, F. Abubakar, Bashiru Ibrahim, M. Usman, Zeenat Bello Kudan","doi":"10.2478/hepo-2019-0025","DOIUrl":"https://doi.org/10.2478/hepo-2019-0025","url":null,"abstract":"Summary Introduction: Nowadays, many synthetic drugs comes with various degrees of side effects, accumulative toxicity and development of resistance by microorganisms. Medicinal plants used worldwide can be developed into modern drugs with little or no side effects and greater efficacy. Objective: The aim of this paper was to document the alternative therapy used in Dutsin-Ma local community in Katsina state, Nigeria. Methods: Ethnobotanical survey was carried out among 40 traditional herbalists. Out of 106 plants found, screening was conducted to include only plants that are prescribed simultaneously by the entire herbalists. Results: We have found 32 species of medicinal plants from 20 families that are used for management and alternative therapy against common ailments such as malaria, diabetes, sickle cell anaemia, hypertension, ulcer, paralysis, typhoid fever and immune deficiency. Conclusion: Traditional medicinal plants provide the alternative therapy for treatment and management of diseases to significant number of people. Herbal practitioners are still relevant to African healthcare system.","PeriodicalId":12990,"journal":{"name":"Herba Polonica","volume":"65 1","pages":"45 - 55"},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44051457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}