Henry Ford Hospital medical journal最新文献

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Antimicrobial chemotherapy in the intensive care unit. 加护病房的抗菌化疗。
Henry Ford Hospital medical journal Pub Date : 1991-01-01
L D Saravolatz
{"title":"Antimicrobial chemotherapy in the intensive care unit.","authors":"L D Saravolatz","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":12988,"journal":{"name":"Henry Ford Hospital medical journal","volume":"39 2","pages":"126-37"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13051102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quality of life: what does it mean? 生活质量:它意味着什么?
Henry Ford Hospital medical journal Pub Date : 1991-01-01
J A DeShano
{"title":"Quality of life: what does it mean?","authors":"J A DeShano","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":12988,"journal":{"name":"Henry Ford Hospital medical journal","volume":"39 2","pages":"89-91"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13051109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Current issues in the leukemias. 白血病的当前问题。
Henry Ford Hospital medical journal Pub Date : 1991-01-01
H R Terebelo
{"title":"Current issues in the leukemias.","authors":"H R Terebelo","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":12988,"journal":{"name":"Henry Ford Hospital medical journal","volume":"39 2","pages":"96-7"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13051110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cushing's disease: dilemmas of diagnosis and management. 库欣病:诊断与治疗的困境。
Henry Ford Hospital medical journal Pub Date : 1991-01-01
M Saeed-uz-Zafar, R C Mellinger, M Wisgerhof
{"title":"Cushing's disease: dilemmas of diagnosis and management.","authors":"M Saeed-uz-Zafar,&nbsp;R C Mellinger,&nbsp;M Wisgerhof","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Determining the cause of Cushing's disease and correcting the abnormality presents a continuing challenge to the clinician despite remarkable advances in diagnostic and therapeutic techniques. We present seven cases to illustrate 1) the classic disorder cured by pituitary adenomectomy; 2) persistence of the disease after adenomectomy; 3) Cushing's disease manifesting in the puerperium and remitting with dopamine agonist therapy; 4) a patient whose disease relapsed at least five times during 20 years of treatment by adrenalectomy, pituitary radiation, mitotane, and pituitary adenomectomy; 5) the Nelson syndrome; 6) the ectopic adrenocorticotropic hormone (ACTH) syndrome in a patient with dexamethasone suppressible urinary cortisol who had a pituitary adenoma which stained positively for ACTH but who was not cured by total hypophysectomy; and 7) a patient whose ACTH-secreting tumor proved fatal despite repeated surgical, radiologic and pharmacologic measures.</p>","PeriodicalId":12988,"journal":{"name":"Henry Ford Hospital medical journal","volume":"39 1","pages":"10-7"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12815892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The role of echocardiography in acute myocardial infarction. 超声心动图在急性心肌梗死中的作用。
Henry Ford Hospital medical journal Pub Date : 1991-01-01
M Alam
{"title":"The role of echocardiography in acute myocardial infarction.","authors":"M Alam","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Our institutional experience with two-dimensional echocardiography and color flow Doppler tests, as well as a review of the literature, reveals that echocardiography is useful in diagnosing myocardial infarction. Furthermore, complications of myocardial infarction such as mitral regurgitation with or without papillary muscle rupture, acquired ventricular septal defect, true and false left ventricular aneurysms, left ventricular thrombi, right ventricular infarction, and pericardial effusion in the setting of acute infarction can be detected by cardiac ultrasound. Echocardiography is also useful in assessing prognosis of postinfarction patients based on degree of left ventricular dysfunction. This test, however, is not 100% sensitive and specific in diagnosing these entities and should be reviewed in context of a patient's history, physical findings, and other laboratory tests.</p>","PeriodicalId":12988,"journal":{"name":"Henry Ford Hospital medical journal","volume":"39 3-4","pages":"165-9"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12966259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lidocaine prophylaxis in acute myocardial infarction. 利多卡因预防急性心肌梗死。
Henry Ford Hospital medical journal Pub Date : 1991-01-01
J E Tisdale
{"title":"Lidocaine prophylaxis in acute myocardial infarction.","authors":"J E Tisdale","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The prophylactic administration of lidocaine for the prevention of primary ventricular fibrillation (VF) following suspected acute myocardial infarction (MI) is controversial. The incidence of primary VF following acute MI ranges from 1.8% to 10.5%. \"Warning arrhythmias\" have not been shown to be reliable predictors of VF. In-hospital prophylactic administration of lidocaine has been shown to decrease the incidence of primary VF, whereas prehospital administration has not. However, prophylactic administration of lidocaine has not been shown to have a beneficial effect on mortality and may in fact increase mortality. The incidence of lidocaine-induced adverse effects during prophylaxis ranges from 4% to 85%, with an average of approximately 35%. In view of the low incidence of primary VF following acute MI, the high incidence of lidocaine-induced adverse effects, and the lack of evidence of beneficial effect on mortality, prophylactic lidocaine administration to all patients with suspected MI is not recommended. The American Heart Association and American College of Cardiology recommend prophylactic lidocaine administration in patients with acute myocardial ischemia or MI who have ventricular premature beats that occur frequently (greater than 6 per minute), are closely coupled (R on T), multiform in configuration, or occur in short bursts of three or more in succession.</p>","PeriodicalId":12988,"journal":{"name":"Henry Ford Hospital medical journal","volume":"39 3-4","pages":"217-25"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12966265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Contemporary approach to thyroid disease emphasizing use of high-sensitivity thyrotropin assays. 强调使用高灵敏度促甲状腺素测定的甲状腺疾病的现代方法。
Henry Ford Hospital medical journal Pub Date : 1991-01-01
C S Feldkamp, M J McKenna
{"title":"Contemporary approach to thyroid disease emphasizing use of high-sensitivity thyrotropin assays.","authors":"C S Feldkamp,&nbsp;M J McKenna","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Capabilities of new high-sensitivity immunoradiometric assays for thyroid-stimulating hormone (TSH-IRMA) to distinguish among hypothyroid, euthyroid, and hyperthyroid subjects and patient groups with low TSH for nonthyroidal causes suggested an algorithmic approach (directed TSH) to the evaluation of patients with suspected thyroid disease. Utilizing the algorithm, a TSH-IRMA result outside normal limits (0.5 to 5.0 mU/L) generates follow-up tests on the same sample. The interpretation of thyroid function tests (TSH-IRMA, thyroxine, resin uptake, free thyroxine index) and associated studies in the context of different clinical settings is reviewed. The approach is a cost-effective and efficient utilization of laboratory services.</p>","PeriodicalId":12988,"journal":{"name":"Henry Ford Hospital medical journal","volume":"39 1","pages":"25-9"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13016430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An ambulatory approach to self-care of diabetes. 糖尿病患者自我护理的门诊方法。
Henry Ford Hospital medical journal Pub Date : 1991-01-01
F W Whitehouse, I J Whitehouse, M S Cox, D M Kahkonen
{"title":"An ambulatory approach to self-care of diabetes.","authors":"F W Whitehouse,&nbsp;I J Whitehouse,&nbsp;M S Cox,&nbsp;D M Kahkonen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Managing the insulin-requiring diabetic patient in an ambulatory setting includes metabolic regulation of the diabetes and education in its self-care. Means of achieving these goals include structured group or one-on-one individualized sessions. Third party policies relating to ambulatory care are challenged and their need for fiscal support emphasized. During the coming decade, diabetic patients should 1) have access to ambulatory care programs for metabolic regulation and education in self-care, 2) expect third party support of these programs, and 3) heighten their own priorities on diabetes care to ensure quality management of their diabetes.</p>","PeriodicalId":12988,"journal":{"name":"Henry Ford Hospital medical journal","volume":"39 1","pages":"35-40"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13016433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nutrition support of HIV+ patients. 艾滋病毒感染者的营养支持。
Henry Ford Hospital medical journal Pub Date : 1991-01-01
J T Dwyer
{"title":"Nutrition support of HIV+ patients.","authors":"J T Dwyer","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Case management strategies for the nutritional support of patients infected with the human immunodeficiency virus (HIV) are evolving as the disease becomes less rapidly fatal and more chronic. Nutritional status changes in advanced HIV infection are similar in many respects to protein-calorie malnutrition. Current clinical effort and research focuses on the beneficial effects of preserving lean body mass and keeping asymptomatic patients in good nutritional status by preventing micronutrient deficiencies and by treating preexisting nutritional problems rather than attempting to intervene late in the disease's course, after secondary malnutrition has already developed. Nutrition support and intervention trials only late in the disease process have not been promising in reversing weight loss once it has occurred. Special diets, such as lactose- or gluten-free diets, may be helpful in some cases as asymptomatic treatment of some opportunistic infections, and such measures may slow additional losses. However, secretory diarrhea, which often seems to be inherent to the disease itself, is not ameliorated by such measures. Current research is focusing on the potential role of glutamine in slowing malabsorption and on combinations of diet and drug treatments. Asymptomatic patients are now the focus of concern. Preserving good nutritional status by attention to preventing weight loss and loss of lean body mass and assuring food safety are primary. Symptomatic patients require specific assistance depending on the presence of opportunistic infections and the drugs required. Specific nutrition support measures depend on whether or not the gut is functional.(ABSTRACT TRUNCATED AT 250 WORDS)</p>","PeriodicalId":12988,"journal":{"name":"Henry Ford Hospital medical journal","volume":"39 1","pages":"60-5"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13016437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Application of the polymerase chain reaction for detection of minimal residual disease of hematologic malignancies. 聚合酶链反应在血液恶性肿瘤微小残留病检测中的应用。
Henry Ford Hospital medical journal Pub Date : 1991-01-01
M S Roth, V H Terry
{"title":"Application of the polymerase chain reaction for detection of minimal residual disease of hematologic malignancies.","authors":"M S Roth,&nbsp;V H Terry","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Current induction therapies for acute and chronic leukemias and the lymphomas have achieved significant complete remission rates. Despite this initial success, disease recurrence remains a major problem. Relapse from clinically undetectable residual malignant cells is the most likely mechanism of recurrence. Of crucial importance to the clinician is the accurate detection of residual malignant cells prior to clinical relapse. Standard approaches to evaluate for this minimal residual disease (MRD) allow detection only when the malignant clone exceeds 1%. Patients in remission, however, may frequently have residual neoplastic cells that are far below this level. Recently, several investigators have adapted the polymerase chain reaction (PCR) to detect tumor-specific DNA or RNA sequences. This approach is highly sensitive (able to detect 1 malignant cell in 10(6) normal cells). The application of this technique to the study of MRD thus far has been limited to tumors in which specific DNA or RNA sequence data are available. This review describes the application of PCR to the detection of MRD in patients with chronic myelogenous leukemia, acute lymphoblastic leukemia, and follicular small cleaved cell lymphoma. Because the number of clinical studies and length of follow-up is limited, detection of MRD by PCR is at present largely a research tool and the biological significance of MRD as determined by PCR must await further studies.</p>","PeriodicalId":12988,"journal":{"name":"Henry Ford Hospital medical journal","volume":"39 2","pages":"112-6"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13050483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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