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Predicting survival in the advanced cancer patient. 预测晚期癌症患者的生存。
Henry Ford Hospital medical journal Pub Date : 1991-01-01
R J Miller
{"title":"Predicting survival in the advanced cancer patient.","authors":"R J Miller","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":12988,"journal":{"name":"Henry Ford Hospital medical journal","volume":"39 2","pages":"81-4"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13051107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Post myocardial infarction risk stratification: 1991 perspective. 心肌梗死后风险分层:1991年的观点。
Henry Ford Hospital medical journal Pub Date : 1991-01-01
M Lesch
{"title":"Post myocardial infarction risk stratification: 1991 perspective.","authors":"M Lesch","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":12988,"journal":{"name":"Henry Ford Hospital medical journal","volume":"39 3-4","pages":"265-71"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12967593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hyperandrogenemia and virilization with simultaneous pituitary and adrenal adenomas. 高雄激素血症和阳刚症并发垂体和肾上腺腺瘤。
Henry Ford Hospital medical journal Pub Date : 1991-01-01
J A Jackson, R C Mellinger
{"title":"Hyperandrogenemia and virilization with simultaneous pituitary and adrenal adenomas.","authors":"J A Jackson,&nbsp;R C Mellinger","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We describe a postmenopausal woman who presented with virilizing hyperandrogenemia and was found to have an intrasellar tumor and a large left adrenal mass. Pathologic studies showed on undifferentiated hypophyseal adenoma with immunostaining for chromogranin only and a benign adrenocortical adenoma. In light of current understanding of the regulation of adrenal androgen secretion and adrenocortical mitogenesis, we postulate that this case may be explained by secretion of adrenal androgen-stimulating and mitogenic factors by the pituitary tumor.</p>","PeriodicalId":12988,"journal":{"name":"Henry Ford Hospital medical journal","volume":"39 1","pages":"22-4"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12842104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recovery of left ventricular function following acute myocardial infarction. 急性心肌梗死后左心室功能的恢复。
Henry Ford Hospital medical journal Pub Date : 1991-01-01
H N Sabbah, P D Stein, M Gheorghiade
{"title":"Recovery of left ventricular function following acute myocardial infarction.","authors":"H N Sabbah,&nbsp;P D Stein,&nbsp;M Gheorghiade","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":12988,"journal":{"name":"Henry Ford Hospital medical journal","volume":"39 3-4","pages":"155-8"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12966257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Caring for the terminally ill: communicating with patients and family. 照顾末期病人:与病人及家属沟通。
Henry Ford Hospital medical journal Pub Date : 1991-01-01
D G Cable
{"title":"Caring for the terminally ill: communicating with patients and family.","authors":"D G Cable","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Caring for terminally ill patients requires effective communication skills. It is important that medical personnel understand appropriate ways to communicate with the patient in order to inform him about his illness, throughout its duration. Physicians must develop an understanding of how patients communicate and ways to respond to that communication. Furthermore, the physician needs to communicate with the family of the terminally ill patient. Effective communication must become a regular part of the treatment.</p>","PeriodicalId":12988,"journal":{"name":"Henry Ford Hospital medical journal","volume":"39 2","pages":"85-8"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13051108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vertebral compression fractures at the onset of acute lymphoblastic leukemia in a child. 儿童急性淋巴细胞白血病发病时椎体压缩性骨折。
Henry Ford Hospital medical journal Pub Date : 1991-01-01
M B Oliveri, C A Mautalen, C A Rodriguez Fuchs, M C Romanelli
{"title":"Vertebral compression fractures at the onset of acute lymphoblastic leukemia in a child.","authors":"M B Oliveri,&nbsp;C A Mautalen,&nbsp;C A Rodriguez Fuchs,&nbsp;M C Romanelli","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A child with acute lymphoblastic leukemia, spinal osteoporosis with vertebral compression fractures, and hypercalcemia appearing early in the course of the hematologic disease was followed for two and a half years. Bone mineral density (BMD), measured by single photon absorptiometry at the radial shaft, was within normal limits for age and sex. However, x-rays of vertebrae and vertebral BMD, measured by dual photon absorptiometry, showed marked demineralization. Despite leukemic remission, the spinal osteoporosis became worse and the patient required aggressive treatment for eight months. Treatment included 50 units of calcitonin subcutaneously every other day, 1,000 mg/day of oral calcium, and 3,000 IU/day of vitamin D. The back pain disappeared quickly, and laboratory controls showed a significant diminution of bone turnover. No new compression fractures occurred. Eighteen months later, the patient continued in remission and menarche had occurred. Dual photon absorptiometry revealed a significant \"catch up\" of the lumbar spine BMD. X-ray examination showed a marked remodeling of the vertebral bodies. BMD measurements in this child indicate that bone loss affected the trabecular bone compartment or occurred only at active bone marrow sites. The rapid clinical amelioration and objective biochemical, densitometric, and radiologic evidence of bone improvement warrant further clinical trials on similarly affected patients.</p>","PeriodicalId":12988,"journal":{"name":"Henry Ford Hospital medical journal","volume":"39 1","pages":"45-8"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12991406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
New purine analogues for the treatment of chronic B-cell malignancies. 治疗慢性b细胞恶性肿瘤的新型嘌呤类似物。
Henry Ford Hospital medical journal Pub Date : 1991-01-01
T E Gribbin
{"title":"New purine analogues for the treatment of chronic B-cell malignancies.","authors":"T E Gribbin","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Adenosine deaminase (ADA), a purine salvage pathway enzyme, appears to play a key role in normal lymphocyte growth, development, and differentiation. Three new purine nucleoside analogues, deoxycoformycin, fludarabine, and 2-chlorodeoxyadenosine, affect the normal function of the purine salvage pathway by inhibiting ADA or by acting as analogs of the ADA substrates. These agents show significant activity in the treatment of chronic B-cell leukemias and low-grade lymphomas. The pharmacology, mechanism of action, and clinical usefulness of these agents are discussed.</p>","PeriodicalId":12988,"journal":{"name":"Henry Ford Hospital medical journal","volume":"39 2","pages":"98-102"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12845260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prehospital care of acute myocardial infarction: a review. 急性心肌梗死院前护理的研究进展
Henry Ford Hospital medical journal Pub Date : 1991-01-01
A R Gokli, J L Kovar, T Kowalenko, R M Nowak
{"title":"Prehospital care of acute myocardial infarction: a review.","authors":"A R Gokli,&nbsp;J L Kovar,&nbsp;T Kowalenko,&nbsp;R M Nowak","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Each year more than 1 million people in the United States suffer from acute myocardial infarction (MI) with most of the deaths occurring within hours of symptom onset. Over the last 25 years, different prehospital systems have evolved throughout the world which allow early cardiac monitoring and treatment of acute MI patients. Thrombolytic therapy in acute MI has been shown to decrease mortality and preserve left ventricular function when administered early after onset of symptoms. The potential role of Emergency Medical Services or Mobile Coronary Care Units in achieving early thrombolysis is under investigation. Several studies of prehospital interventions to achieve early thrombolysis are reviewed. The use of thrombolytics by prehospital personnel has been found to be feasible, safe, and effective in reducing time delays. However, whether this translates into clinical benefit remains to be seen.</p>","PeriodicalId":12988,"journal":{"name":"Henry Ford Hospital medical journal","volume":"39 3-4","pages":"170-5"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12966260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intravenous nitroglycerin for acute myocardial infarction. 静脉注射硝酸甘油治疗急性心肌梗死。
Henry Ford Hospital medical journal Pub Date : 1991-01-01
S Borzak
{"title":"Intravenous nitroglycerin for acute myocardial infarction.","authors":"S Borzak","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Intravenous nitroglycerin (IV TNG) has been increasingly used in the setting of acute myocardial infarction. The seven randomized trials comparing IV TNG with placebo, and one trial comparing IV isosorbide dinitrate with furosemide, were reviewed for evidence of beneficial clinical effects. IV TNG in low dosage is safe in the setting of acute myocardial infarction and modestly effective in relieving chest pain. Favorable hemodynamic effects are most pronounced in patients with congestive heart failure. Limited evidence suggests that IV TNG, particularly when administered early, reduces both infarct size and mortality when given prophylactically.</p>","PeriodicalId":12988,"journal":{"name":"Henry Ford Hospital medical journal","volume":"39 3-4","pages":"206-9"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12966263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Measurement of left ventricular ejection fraction using gated 99mTc-sestamibi myocardial planar images: comparison to contrast ventriculography. 用门控99mTc-sestamibi心肌平面图像测量左心室射血分数:与心室造影的比较。
Henry Ford Hospital medical journal Pub Date : 1991-01-01
D A Parker, R L Lloret, F Barilla, L Douthat, M Gheorghiade
{"title":"Measurement of left ventricular ejection fraction using gated 99mTc-sestamibi myocardial planar images: comparison to contrast ventriculography.","authors":"D A Parker,&nbsp;R L Lloret,&nbsp;F Barilla,&nbsp;L Douthat,&nbsp;M Gheorghiade","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Using the new myocardial perfusion agent 99mTc-sestamibi and multigated acquisition on a nuclear medicine gamma camera, the left ventricular ejection fraction (LVEF) was derived in 13 patients with coronary artery disease (CAD). Cross-sectional activity profiles were used to measure the left ventricle from end-diastolic and end-systolic images. Several different geometric methods were then utilized to derive ejection fractions from the nuclear data. Comparison of the resultant ejection fractions to those obtained from contrast ventriculography showed significant correlation for all geometric methods (P less than 0.01, Sy X x = 6.2 to 9.6). We conclude that in patients with CAD one or more of these simple geometric methods can provide a useful estimate of the LVEF when performing 99mTc-sestamibi multigated myocardial perfusion imaging.</p>","PeriodicalId":12988,"journal":{"name":"Henry Ford Hospital medical journal","volume":"39 1","pages":"56-9"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12991407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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