Health and Quality of Life Outcomes最新文献

{"title":"Quality of measurement instruments assessing Planetary and One Health Literacy related constructs: a systematic review.","authors":"Lydia Reismann, Jennifer Kallenbach, Christian Apfelbacher, Theresa Donhauser, Claudia Hasenpusch, Jana Hinneburg, Anke Steckelberg, Carmen Jochem","doi":"10.1186/s12955-026-02652-3","DOIUrl":"10.1186/s12955-026-02652-3","url":null,"abstract":"<p><strong>Background: </strong>Amid accelerating anthropogenic climate and ecological crises, the expansion of health literacy as a comprehensive and multidimensional concept addressing upstream determinants of health has become relevant. A critical gap persists in measurement research to identify validated instruments for health literacy within the environment-health nexus.</p><p><strong>Objective: </strong>To conduct a systematic review of the quality of existing instruments that measure Planetary and One Health Literacy or related constructs according to the COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) methodology.</p><p><strong>Methods: </strong>A systematic literature search was performed in Medline, Embase, Web of Science, CINAHL, APA PsychInfo, APA PsycArticles, PSYNDEX, and Greenline to identify development and/or validation studies of suitable instruments. We assessed the risk of bias of each study, systematically evaluated the psychometric properties of instruments, and graded the certainty of evidence to inform recommendations for instrument use and further development.</p><p><strong>Results: </strong>Out of 192 screened records, we identified four studies employing three instruments: Climate Change Health Literacy Scale (CCHLS), Climate Change and Infectious Disease Literacy Scale, and Sustainable Food Literacy Scale (SFLS). The quality of evidence for the development and content validity in all instruments was rated low or very low. Of all scales the SFLS demonstrated the best results in the assessed measurement properties supported by very good quality of evidence in its original, while its Turkish adaptation had low methodological quality in its assessed measurement properties and insufficient reliability.</p><p><strong>Conclusion: </strong>The included studies emphasised quantitative validation over robust instrument development and transparency in their reporting, highlighting the need for clearly defining constructs and involving target populations in the design processes. While existing measurement instruments primarily assess knowledge, attitudes, and behaviour, the lack of attention to the health literacy's construct calls for stronger integration between health literacy, Planetary Health, and One Health research.</p>","PeriodicalId":12980,"journal":{"name":"Health and Quality of Life Outcomes","volume":"24 1","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13675952/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149206762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Economic toxicity and quality of life in stroke patients: a moderated mediation model of self-management and family function.","authors":"Lili Yao, Shan He, Yi Duan, Qing Liu, Yanhui Du, Yetao Luo, Ling Xiao, Ling Liu","doi":"10.1186/s12955-026-02609-6","DOIUrl":"10.1186/s12955-026-02609-6","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the relationships among economic toxicity, family function, self-management ability, and stroke-specific quality of life in stroke patients during the rehabilitation period, and to construct and test a moderated mediation model with self-management as the mediator and family function as the moderator, so as to provide empirical evidence for improving the quality of life of stroke patients.</p><p><strong>Methods: </strong>A cross-sectional survey was conducted from May to June 2025 across 22 medical and elderly care institutions in Chongqing, China. A total of 557 stroke patients in the rehabilitation period completed questionnaires measuring sociodemographics, economic toxicity (COST-PROM), family function (Family APGAR Scale), self-management (Stroke Self-Management Scale), and stroke-specific QoL (SS-QOL Scale). The moderated mediation model was tested using the PROCESS macro in SAS 9.4.</p><p><strong>Results: </strong>Economic toxicity was significantly negatively correlated with quality of life (r = -0.424, P < 0.001); self-management played a partial mediating role between economic toxicity and quality of life, with the mediating effect accounting for 50.56%; family function played a significant buffering moderating role between economic toxicity and self-management (β = 0.209, P < 0.001), and high family function could significantly weaken the negative impact of economic toxicity on self-management.</p><p><strong>Conclusion: </strong>Economic toxicity impairs QoL both directly and indirectly through reduced self-management. Strong family function buffers the detrimental effect of economic toxicity on self-management. Interventions targeting economic toxicity screening, self-management support, and family empowerment may help improve QoL in stroke survivors and warrant prospective evaluation.</p>","PeriodicalId":12980,"journal":{"name":"Health and Quality of Life Outcomes","volume":"24 1","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13625440/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149080796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Measuring children's HRQoL via self-reports and parent proxy-reports in the French Enabee 2022 study: an evaluation of the psychometric properties of both versions of the French KINDL-R questionnaire.","authors":"Naomi Benhaddou, Valentina Decio, Yvon Motreff, Nolwenn Regnault, Stéphanie Monnier-Besnard, Jean-Benoit Hardouin, Alexandra Rouquette","doi":"10.1186/s12955-026-02589-7","DOIUrl":"https://doi.org/10.1186/s12955-026-02589-7","url":null,"abstract":"<p><strong>Introduction: </strong>Child well-being policies require quality data that takes children's perspectives into account, recorded through appropriate, accurate and reliable measurement instruments. This study evaluated the psychometric properties of two versions of the KINDL-R questionnaire used in the 2022 French National Study on Children's Well-being (Enabee) to assess Health-Related Quality of Life (HRQoL) in children: a self-report version for elementary school children aged 6-11 (n = 15,114), and a parent-report version for preschool and kindergarten children aged 3-6 (n = 3,785).</p><p><strong>Methods: </strong>We examined the distributions of responses and the correlations between items. We performed confirmatory factor analysis (CFA) and exploratory structural equation modelling (ESEM) to assess the fit of first- and second-order factor models. Internal consistency was measured using McDonald's omega. We tested measurement invariance across child's gender, grade, type of school and whether or not they had a chronic illness. We also conducted a known-groups analysis via analysis of variance (ANOVA) based on child's chronic illness, mental health and parental educational attainment.</p><p><strong>Results: </strong>The parent-report version demonstrated satisfactory CFA model fit (CFI = 0.915, TLI = 0.901, RMSEA = 0.072, SRMR = 0.073), supporting dimensional scoring. The acceptable fit of the hierarchical model (CFI = 0.916, TLI = 0.905, RMSEA = 0.073, SRMR = 0.075) provides preliminary support for reporting an overall score. Invariance was confirmed for the child's gender, grade, type of school and chronic illness. This version effectively distinguished between children with chronic illnesses or at least one probable mental health difficulty and healthy peers. However, the self-report version lacked factorial validity and showed poor CFA model fit (CFI = 0.757, TLI = 0.717). The ESEM model provided a detailed assessment of the fitting issues, which were primarily related to the emotional well-being dimension.</p><p><strong>Conclusion: </strong>The parent-report version of the Kiddy-KINDL-R can provide a valid measure of HRQoL for French children aged 3-6 with comparable mean scores across groups. However, the proposed factor structure of the self-report version of the Kid-KINDL-R was not supported, and most subscales showed insufficient internal consistency in elementary school children. Further refinement is thus required. This was the first study to evaluate the psychometric properties of the KINDL-R measure in the French general population. It provided critical, reliable, and unprecedented information about measuring children's HRQoL.</p>","PeriodicalId":12980,"journal":{"name":"Health and Quality of Life Outcomes","volume":"24 1","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149060458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Structured, expert-informed selection and harmonization of patient-reported outcome measures (PROMs) in a German multicenter network: the post-COVID syndrome use case.","authors":"Evelyne Hanc, Katharina Koller, Regina Herold, Luisa Balz, Alexa Kupferschmitt, Deborah Erhart, Jonathan Mang, Bernd Löwe, Volker Köllner, Stephan Frisch, Yesim Erim, Eva Morawa","doi":"10.1186/s12955-026-02631-8","DOIUrl":"10.1186/s12955-026-02631-8","url":null,"abstract":"<p><strong>Background: </strong>Patient-reported outcome measures (PROMs) provide subjective information on symptoms, functional ability or quality of life. In post-COVID syndrome (PCS), lacking clear diagnostic criteria or biomarkers, PROMs enable a differentiated assessment of disease course and treatment effects. Within a multicenter research project (EMOPROM LCN), a structured selection process for PROMs was conducted to reach consensus on a validated PROMs battery for PCS, suitable for studies and clinical care, and transferable to other complex conditions.</p><p><strong>Methods: </strong>An interdisciplinary committee identified key symptoms/syndromes and constructs (e.g., fatigue, depression, post-exertional malaise) and selected PROMs through a structured, expert-based consensus process considering psychometric properties, clinical relevance, feasibility, time efficiency and applicability within the German healthcare context. The questionnaires were organized into thematic domains and compiled into a modular test battery.</p><p><strong>Results: </strong>The following 13 questionnaires were included in the final PROMs battery: Post-COVID Syndrome Score (PCS-Score), Post-COVID Functional Status Scale (PCFS), Fatigue Scale for Motor and Cognitive Functions (FSMC), Patient Health Questionnaire-9 (PHQ-9), Generalized Anxiety Disorder Scale 7 (GAD-7), DePaul Symptom Questionnaire - Post-exertional malaise (DSQ-PEM), Insomnia Severity Index (ISI), Somatic Symptom Scale-8 (SSS-8), Somatic Symptom Disorder - B Criteria Scale (SSD-12), EuroQoL Five-Dimension Five-Level Questionnaire (EQ-5D-5L), Pain Disability Index (PDI), Primary Care PTSD Screen for DSM-5 (PC-PTSD-5), PROMIS v2.0 Cognitive Function Short Form 6.</p><p><strong>Conclusion: </strong>The battery offers a selection of validated, time-efficient, and mostly free assessment tools, particularly valuable in specialized care. For routine practice, targeted partial use is recommended. The structured EMOPROM LCN selection process illustrates how clinically relevant, validated and patient-centered assessment instruments can be harmonized for multicenter research and care. PROMs hold considerable potential for improving the quality of care in post-infectious syndromes.</p>","PeriodicalId":12980,"journal":{"name":"Health and Quality of Life Outcomes","volume":"24 1","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13615613/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149060493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes in health-related quality of life: a longitudinal registry study among over 15,000 participants of a digital education and exercise therapy for knee and hip osteoarthritis using EQ-5D-5L.","authors":"Ali Kiadaliri, Andrea Dell'Isola, Armaghan Mahmoudian, Leif E Dahlberg, L Stefan Lohmander","doi":"10.1186/s12955-026-02634-5","DOIUrl":"10.1186/s12955-026-02634-5","url":null,"abstract":"<p><strong>Objective: </strong>To explore changes in health-related quality of life (HRQoL) measured using EQ-5D-5L among participants of a digital education and exercise therapy for knee and hip osteoarthritis (OA).</p><p><strong>Methods: </strong>A descriptive longitudinal registry-based study among participants aged 40 + years enrolled in the digital program with responses to EQ-5D-5L at enrolment and at least one follow-up at 3- [n = 15147] or 12-months [n = 4586]. Changes in EQ-5D-5L profile from enrolment were examined using the Paretian classification of health change (PCHC).</p><p><strong>Results: </strong>At enrolment, selfcare and pain/discomfort were the EQ-5D-5L dimensions with the least and most reported problems, respectively. The percentages of participants reporting improvements in EQ-5D-5L dimensions ranged from 12.9% (14.0%) for selfcare to 33.0% (38.4%) for pain/discomfort at 3 (12) months follow-ups. The corresponding percentages in reporting worsening ranged from 8.0% for selfcare to 15.4% for usual activities at 3 months and from 10.0% for selfcare to 16.4% for mobility at 12 months. At all timepoints, \"slight problems\" in the pain/discomfort dimension and no problems in other dimensions (the EQ-5D-5L profile \"11121\") was the most common profile. The PCHC analysis suggested that at 3/12 months follow-ups, the EQ-5D-5L profiles improved for 46.9%/50.4% of participants, worsened for 19.5%/20.1%, showed mixed changes for 19.7%/18.7% and remained unchanged for 13.9%/10.9%.</p><p><strong>Conclusion: </strong>In this single-arm registry study, about half of participants reported improved EQ-5D-5L profiles at 3 and 12 months following digital education and exercise therapy, while one-fifth reported worsening and another one-fifth showed mixed changes, indicating heterogeneous HRQoL trajectories and the need for tailored participant support.</p>","PeriodicalId":12980,"journal":{"name":"Health and Quality of Life Outcomes","volume":"24 1","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13591732/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149012216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nutrition knowledge, attitude, and practice in relation to health-related quality of life among urban-poor children in Malaysia: the mediating role of lifestyle factors.","authors":"Joseph Mun Hong Cheah, Yit Siew Chin, Hazizi Abu Saad, Poh Ying Lim, Yoke Mun Chan, Zalilah Mohd Shariff","doi":"10.1186/s12955-026-02564-2","DOIUrl":"10.1186/s12955-026-02564-2","url":null,"abstract":"<p><strong>Background: </strong>Children living in urban-poor communities are particularly vulnerable to poor health-related quality of life (HRQoL) because socioeconomic disadvantage, food insecurity, constrained food environments, and limited access to health-promoting resources may affect both nutritional status and psychosocial well-being. Although nutrition knowledge, attitude, and practice (KAP) are known to influence children's health behaviours, the behavioural pathways through which these factors affect HRQoL remain insufficiently understood. This study examined the interrelationships between nutrition KAP, lifestyle-related behaviours, body composition, and HRQoL among children from urban-poor flats using serial mediation analysis.</p><p><strong>Methods: </strong>A cross-sectional study was conducted using cluster sampling to recruit eligible participants from ten urban-poor flats in Kuala Lumpur, Malaysia. Participants completed a sociodemographic questionnaire, nutrition knowledge, attitude, and practice (KAP) questionnaire, Eating Behaviours Questionnaire (EBQ), Physical Activity Questionnaire for Older Children (PAQ-C), and Pediatric Quality of Life Inventory™ (PedsQL™) 4.0. The body composition of the children was also measured using InBody 270s bioelectrical impedance analysis. Serial mediation analysis was conducted through path analysis to evaluate the inter-relationships between variables.</p><p><strong>Results: </strong>A total of 408 children (mean age = 9.7 years) were recruited. Nutrition attitude significantly mediated the relationship between nutrition knowledge and nutrition practice (b = 0.034, 95% CI: 0.019, 0.054). Nutrition knowledge showed no significant direct effect on HRQoL but demonstrated significant indirect effects through multiple behavioural pathways (p < 0.05), particularly through nutrition attitude, nutrition practice, fast-food intake, supper intake, and physical activity. The final model explained 32.1% of the variance in HRQoL.</p><p><strong>Conclusion: </strong>These findings suggest that nutrition KAP influences HRQoL primarily through modifiable lifestyle-related behaviours rather than through a direct pathway. Interventions for children in urban-poor communities should therefore combine nutrition knowledge enhancement with strategies that strengthen attitudes, support healthier practices, reduce unhealthy eating behaviours, and promote physical activity.</p>","PeriodicalId":12980,"journal":{"name":"Health and Quality of Life Outcomes","volume":"24 1","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13546513/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148897281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Time-dependent analysis of HUS change in older patients aged > 75 years with head and neck cancer.","authors":"Danni Cheng, Katrina Hueniken, Andrew Hope, Shao Hui Huang, Anna Spreafico, David P Goldstein, Scott V Bratman, Yu Zhao, Jianjun Ren, John R de Almeida, Wei Xu, Geoffrey Liu","doi":"10.1186/s12955-026-02551-7","DOIUrl":"https://doi.org/10.1186/s12955-026-02551-7","url":null,"abstract":"<p><strong>Background: </strong>Previous longitudinal evidence has suggested that patients aged > 75 years may be associated with a poorer Health Utility Index Mark 3 (HUI-3) trajectory. We compared the longitudinal health utility scores (HUS) of older (>75 years) versus younger patients with head and neck cancers across various clinical subgroups and identified factors associated with decline in quality of life.</p><p><strong>Methods: </strong>The study prospectively collected clinical information and follow-up data from head and neck cancer patients. The HUI-3 scale was used to assess changes in health-related quality of life at baseline, post-surgery, mid-radiation therapy, and at 3, 6, and 12 months. A linear mixed model was employed to evaluate the changes in HUS and age categories over time.</p><p><strong>Results: </strong>We included 859 patients with head and neck cancer, of whom 647 were included in the longitudinal analytic cohort. In descriptive analyses, patients aged > 75 years showed less complete recovery in mean HUS after early treatment-related decline compared with younger patients. In the primary mixed-effects model, younger age groups had more positive average HUS slopes than patients aged > 75 years. However, these age-related differences were attenuated and were no longer statistically supported after adjustment for clinical stage, Eastern Cooperative Oncology Group (ECOG) performance status, and treatment modality. Subgroup findings were exploratory and were not consistently supported across all model-based comparisons.</p><p><strong>Conclusion: </strong>Patients aged > 75 years may be at risk for slower or incomplete post-treatment recovery in HUI-3-derived health utility. These findings should be interpreted cautiously given potential selection bias, missing data, and attenuation after covariate adjustment. Larger studies with detailed geriatric and domain-specific functional measures are needed to confirm these patterns.</p>","PeriodicalId":12980,"journal":{"name":"Health and Quality of Life Outcomes","volume":"24 1","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13480271/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148792452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations of reallocating time between physical activity, sedentary behavior, and sleep with mental health among Chinese adolescents: an isotemporal substitution analysis.","authors":"Jian Wu, Yongji Gao, Xuejun Chi, Haiyang Feng, Qiurui Yu, Yongjin Chen, Jieqiong Qin, Yinmei Yang","doi":"10.1186/s12955-026-02611-y","DOIUrl":"10.1186/s12955-026-02611-y","url":null,"abstract":"<p><strong>Background: </strong>Depression and anxiety are important adolescent mental health concerns and may be linked to modifiable movement behaviors, including physical activity (PA), sedentary behavior (SB), and sleep. As mental health outcomes depend not only on time spent in specific behaviors but also on the trade-offs between them, this study examined the associations of reallocating 30 min between these behaviors with adolescent psychological symptoms.</p><p><strong>Methods: </strong>This cross-sectional study included 7,767 adolescents from Henan Province, Central China, in 2023. Daily PA, SB, and sleep duration were self-reported. Depressive symptoms were assessed using the 10-item Center for Epidemiologic Studies Depression Scale, and anxiety symptoms were measured with the 7-item Generalized Anxiety Disorder Scale. Isotemporal substitution models estimated the associations of 30-minute reallocations with depressive and anxiety symptoms. Interaction tests and subgroup analyses were conducted according to sleep status.</p><p><strong>Results: </strong>Replacing 30 min of SB with sleep or PA was associated with lower levels of depression (sleep, B = -0.47, 95%CI = -0.53~-0.41; PA, B = -0.12, 95%CI = -0.16~-0.08) and anxiety (sleep, B = -0.31, 95%CI = -0.36~-0.25; PA, B = -0.07, 95%CI = -0.10~-0.04). Reallocating PA to sleep also related to reduced depressive symptoms (B = -0.35, 95%CI = -0.42~-0.28) and anxiety symptoms (B = -0.24, 95%CI = -0.30~-0.18). Among adolescents with insufficient sleep, the associations were stronger when reallocating SB to sleep (for depression: B = -0.52, 95%CI = -0.64~-0.39; for anxiety: B = -0.40, 95%CI = -0.50~-0.28) or PA to sleep (for depression: B = -0.39, 95%CI = -0.50~-0.25; for anxiety: B = -0.32, 95%CI = -0.41~-0.19). Among those with sufficient sleep, reallocating SB to PA or sleep remained associated with lower depressive symptoms, but no significant association was observed for anxiety.</p><p><strong>Conclusions: </strong>Reallocating time toward sleep and PA was associated with reduced depressive and anxiety symptoms, particularly among adolescents with insufficient sleep. Accounting for sleep status may help advance understanding of the associations between movement behavior reallocations and adolescent mental health.</p>","PeriodicalId":12980,"journal":{"name":"Health and Quality of Life Outcomes","volume":"24 1","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13499305/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148792522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral health-related quality of life in patients receiving dental treatment from dental therapists.","authors":"Emma Louwagie, Michelle C Arnett, Aparna Ingleshwar, Mike T John, Danna R Paulson, Yvette G Reibel, Phonsuda Chanthavisouk","doi":"10.1186/s12955-026-02572-2","DOIUrl":"10.1186/s12955-026-02572-2","url":null,"abstract":"<p><strong>Purpose: </strong>Oral health-related quality of life (OHRQoL) measured by the 5-item Oral Health Impact Profile (OHIP-5) allows characterization of patients' oral health impact into normative values in a university setting. This study aims to derive OHIP-5 normative values for patients seeking care from the dual degree student provider of the dental hygienist and dental therapist in Minnesota.</p><p><strong>Methods: </strong>Normative OHIP-5 values were determined in n = 2,835 patients at the University of Minnesota School of Dentistry, representing sample-based reference distributions. Summary scores were analysed using an empirical cumulative distribution function, with the 90th percentile threshold indicating typical versus elevated impact, while dimensional scores (Oral Function, Orofacial Pain, Orofacial Appearance, and Psychosocial Impact) assessed as elevated impact were considered frequent item response categories \"fairly often\" or \"very often\".</p><p><strong>Results: </strong>The vast majority (90%) of patients seeking care from the dual degree student providers presented an OHIP-5 score of 6 or less, characterizing OHIP-5 scores of 7-20 points as \"non-typically elevated\". The \"non-typically elevated\" dimension scores occurred in 7% of patients for Oral Function, 6% for Orofacial Pain, 11% for Orofacial Appearance, and 2% for Psychosocial Impacts.</p><p><strong>Conclusion: </strong>Understanding normative OHIP-5 values in patient populations treated by dual degree student providers in dental school settings supports clinical decision-making by guiding diagnostic, referral, and treatment pathways. Their role in preventive and restorative care advances patient-centered outcomes, aligning with the quadruple aim of healthcare.</p>","PeriodicalId":12980,"journal":{"name":"Health and Quality of Life Outcomes","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148548804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Variations in health-related quality of life across sociodemographic groups, health conditions, and modifiable risk factors: a population-based EQ-5D-3L study.","authors":"Mihretab Gebreslassie, Stefan Fors, Per Tynelius, Mathieu F Janssen, Sofia Sveréus, Emelie Heintz","doi":"10.1186/s12955-026-02587-9","DOIUrl":"10.1186/s12955-026-02587-9","url":null,"abstract":"<p><strong>Background: </strong>EQ-5D is widely used in economic evaluations and population health assessments. This study used a large population-based cohort with EQ-5D-3L data to describe the health-related quality of life (HRQoL) of the general population in Stockholm County and investigate potential inequalities and variations in HRQoL.</p><p><strong>Methods: </strong>This study analysed data from 52,714 respondents aged 23-104 years from the 2021 Stockholm Public Health Cohort (SPHC). Calibration weights were used to address non-response bias and improve representativeness. Differences in mean EQ-VAS and EQ-5D-3L index values were analyzed using multivariable regressions, and modified poison regression was used to explore the likelihood of reporting problems across the EQ-5D dimensions. Splines were used to flexibly model the nonlinear relationship between age and HRQoL.</p><p><strong>Results: </strong>A total of 169 health states were observed, with 37% of the respondents reporting \"no problems\" in all dimensions (\"11111\"). Further, 0.05% (n = 14) respondents reported the worst possible health state (\"33333\"). The HRQoL of the general population was generally good but variations across sociodemographic and risk factor groups were observed. HRQoL demonstrated a non-linear relationship with age, with relatively lower scores observed among the youngest adults, increasing through midlife, followed by a marked decline in older age, particularly among those aged 80 years and above. The mean EQ-5D-3 L index was lower among females (0.79 [95% CI: 0.79-0.80]) than males (0.83 [95% CI: 0.83-0.84]), and a similar pattern was observed for the mean EQ-VAS scores (75.96 [95% CI: 75.59-76.33] vs. 78.3 [95% CI: 77.62-78.42], respectively). People with lower education, low disposable income as well as those born outside of the European union and UK reported relatively lower HRQoL. Adjusting for age attenuated but did not eliminate these demographic and socioeconomic differences. Persistent associations between behavioural risk factors and HRQoL were also observed. Similarly, people with chronic health conditions, particularly those with long-term illness or multiple health conditions, exhibited markedly lower HRQoL.</p><p><strong>Conclusion: </strong>This study demonstrated substantial variations in HRQoL across sociodemographic groups, behavioural risk factors, and self-reported health conditions, providing insights that can inform healthcare planning and future investments in health and research. The results may also serve as reference values in clinical and economic evaluations, and for comparing outcomes from specific patient subgroups with the general population.</p>","PeriodicalId":12980,"journal":{"name":"Health and Quality of Life Outcomes","volume":"24 1","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13386571/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148535706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}