{"title":"Psychometric properties of the Persian version of the childhood epilepsy questionnaire-16 (QOLCE-16) in a sample of parents of children with epilepsy.","authors":"Hamid Nemati, Parvin Ghaemmaghami, Leila Roosta, Seyedeh Leila Dehghani, Marzieh Alamolhoda","doi":"10.1186/s12955-026-02504-0","DOIUrl":"10.1186/s12955-026-02504-0","url":null,"abstract":"<p><p>BACKGROUND: As a chronic neurological condition, epilepsy adversely affects multiple dimensions of quality of life in pediatric and adolescent populations. The aims of the study were translation and cultural adaptation (TCA) of the Persian version of the 16-item Quality of Life in Childhood Epilepsy (QOLCE-16) and assessment of its psychometric properties in children and adolescents with epilepsy. METHODS: A total of 290 parents of children with epilepsy were eligible to participate in this study and completed the questionnaire. TCA procedures were used to adapt the English version of the QOLCE-16 into Persian. Reliability, internal consistency, item analysis, test-retest reliability, convergent validity, discriminant validity, and confirmatory factor analysis (CFA) were conducted to evaluate the psychometric properties of the Persian version of the QOLCE-16. RESULTS: Internal consistency measured by Cronbach’s alpha coefficients was excellent, ranging from 0.80 to 0.92. The items were significantly related to the total scores (p < 0.05). Intraclass correlation coefficients were satisfactory across all domains. Convergent and discriminant validity were supported for all subscales based on predefined correlation-based criteria. The results of CFA confirmed a second-order model with excellent fit based on significant standardized estimates of factor loadings and favorable goodness-of-fit indices (CFI = 0.979, TLI = 0.973, RMSEA = 0.062, 90% CI [0.048, 0.076], and SRMR = 0.062). CONCLUSIONS: The Persian version of the QOLCE-16 has good reliability and validity in assessing the health-related quality of life of children with epilepsy in Iran. The translated version, as a brief and valuable measurement tool, can be applied in clinical research of a Persian-speaking population. </p>","PeriodicalId":12980,"journal":{"name":"Health and Quality of Life Outcomes","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13040998/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147305166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yanming Hong, Zhihao Yang, Nan Luo, Jan Busschbach
{"title":"Anxiety and depression may amplify self-reported physical health problems: evidence from EQ-5D-5L data.","authors":"Yanming Hong, Zhihao Yang, Nan Luo, Jan Busschbach","doi":"10.1186/s12955-026-02497-w","DOIUrl":"10.1186/s12955-026-02497-w","url":null,"abstract":"<p><p>INTRODUCTION: Our previous study has shown that individuals with poor positive mental well-being (measured by the Short Warwick-Edinburgh Mental Well-being Scale, SWEMWBS) tend to report more problems on the EQ-5D-5L. Another study has shown that the anxiety/depression item of the EQ-5D-5L and all items of SWEMWBS loaded onto the same factor in an exploratory factor analysis, suggesting they measure the same construct. This study aims to analyze the potential impact of anxiety/depression on responses to the four physical health dimensions of the EQ-5D-5L. METHODS: An online survey and face-to-face interviews were conducted to collect data from participants with and without different health conditions. Generalized ordered logistic regression was employed to examine the influence of anxiety/depression on responses to the four physical health dimensions of the EQ-5D-5L. Multiple linear regression analysis was conducted to explore the effects of anxiety/depression on EQ-VAS and utility values. A directed acyclic graph (DAG) was used to identify the minimum set of variables required to adjust for confounding. RESULTS: 500 participants completed online surveys, 509 participated in face-to-face interviews; 237 healthy individuals, 430 individuals with physical conditions, 234 with mental conditions, and 108 with both physical and mental conditions. According to graphical rules applied to the DAG, the final minimally sufficient adjustment set comprised age, carers, education level, sex, and health conditions. Generalized ordered logistic regression indicated that individuals with higher levels of anxiety/depression were more likely to report problems in the four physical health dimensions. Multiple linear regression analysis demonstrated that anxiety/depression was significantly associated with EQ-5D-5L utility values and EQ-VAS scores, with individuals experiencing high levels of anxiety/depression reporting lower values for both measures. CONCLUSION: Mental health conditions, particularly anxiety and depression, may lead to heightened perceptions of problems in physical health dimensions, potentially biasing self-reported health data. Addressing anxiety and depression in clinical and therapeutic settings may not only improve mental health outcomes but also positively influence perceived physical health. Future research is needed to establish causal relationships. </p>","PeriodicalId":12980,"journal":{"name":"Health and Quality of Life Outcomes","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13040876/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147305097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Validity and reliability of the Japanese Adult Social Care Outcomes Toolkit four-level Self Completion Tool (ASCOT SCT4) in community mental health service users in Japan.","authors":"Mayui Nara, Sosei Yamaguchi, Yoko Moriyama, Takashi Okada, Kentaro Usuda, Ayako Hada, Kaori Usui, Mai Iwanaga, Takayuki Kawaguchi, Sayaka Sato, Naoaki Kuroda, Chiyo Fujii","doi":"10.1186/s12955-026-02499-8","DOIUrl":"10.1186/s12955-026-02499-8","url":null,"abstract":"<p><p>BACKGROUND: Outcome evaluations using patient-reported outcome measures (PROMs) are becoming increasingly important in healthcare, including long-term care and disability support. The Adult Social Care Outcomes Toolkit (ASCOT) is a self-reported measure that assesses social care-related quality of life (SCRQoL), which can be affected by long-term care services. This study examined the validity and reliability of the Japanese ASCOT four-level Self-Completion Tool (SCT4) for people with mental illnesses who used community services. METHODS: We conducted a cross-sectional survey of persons with mental illnesses who used community services in 22 facilities across Japan. Confirmatory factor analysis (CFA) was performed to confirm the factor structure. Spearman’s rank correlation coefficients were calculated to assess the convergent validity of health-related quality of life (HRQoL), personal agency, well-being, depressive symptoms, functional assessment, and objective quality of life (QoL). Cronbach’s alpha and intra-class correlation coefficients (ICC) were computed to assess internal consistency and test-retest reliability, respectively. RESULTS: In total, 397 service users agreed to participate, and 64 completed the Japanese ASCOT SCT4 twice to assess test-retest reliability. The model fit indices indicated chi-squared statistic /degrees of freedom (CMIN/df) = 1.069 (p = 0.375), root mean square error of approximation (RMSEA) = 0.013, standardized root mean square residual (SRMR) = 0.026, comparative fit index (CFI) = 0.998, and Tucker-Lewis index (TLI) = 0.997. The Japanese ASCOT SCT4 demonstrated significant correlations with HRQoL (ρ = 0.619, p < 0.001), personal agency (ρ = 0.502, p < 0.001), well-being (ρ = 0.657, p < 0.001), depressive symptoms (ρ = -0.657, p < 0.001), and functional assessment (self-reported version: ρ = -0.616, p < 0.001; observer-reported version: ρ = -0.242, p < 0.001), and objective QoL (ρ = 0.240, p < 0.001). Cronbach’s alpha and ICC were 0.76 and 0.71, respectively. CONCLUSIONS: The Japanese ASCOT SCT4 can be potentially useful as a PROM to easily assess the SCRQoL of individuals with mental illness who use community services. Future studies should use additional validity tests with more diverse samples. </p>","PeriodicalId":12980,"journal":{"name":"Health and Quality of Life Outcomes","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13020357/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146226706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jan Georg Friesinger, Dina von Heimburg, Ottar Ness, Siri Håvås Haugland, John-Kåre Vederhus
{"title":"Discrimination experiences and their associations with sociodemographic factors, health and quality of life-a latent class analysis.","authors":"Jan Georg Friesinger, Dina von Heimburg, Ottar Ness, Siri Håvås Haugland, John-Kåre Vederhus","doi":"10.1186/s12955-026-02502-2","DOIUrl":"10.1186/s12955-026-02502-2","url":null,"abstract":"<p><strong>Background: </strong>Discrimination has adverse effects on people's health and quality of life (QoL). This study aimed to identify distinct intersecting patterns of discrimination experiences, examine their associations with social categories and health factors, and assess the impact of perceived discrimination (PD) on health and QoL outcomes beyond specific self-reported reasons for PD.</p><p><strong>Methods: </strong>We utilized data from the Norwegian Counties Public Health Survey (NCPHS) conducted in Agder County in 2023 and employed latent class analysis (LCA) to explore how patterns of discrimination reasons cluster. The selected classes were then further examined to determine how they differed by comparing each class to the reference class with no PD. Lastly, we assessed the estimated marginal means of each class on health and overall QoL using ANCOVA.</p><p><strong>Results: </strong>The study identified six classes of PD: Massive PD, Gender/Age PD, No PD, Function/Illness PD, Ethnicity/Skin PD, and Political PD. ANCOVA analyses revealed significant differences across self-rated health, mental distress, and QoL. Notably, the Massive PD, Gender/Age PD, and Function/Illness PD groups reported significantly poorer self-rated health and QoL compared to the No PD group. All PD classes scored significantly higher in mental distress than the No PD group, with the Massive PD class exceeding the clinical cut-off, indicating elevated psychological distress.</p><p><strong>Conclusions: </strong>Our findings reveal persistent health and QoL disparities between individuals experiencing PD and those who do not, despite a robust welfare system. Service providers must consider the interplay of factors such as age, gender, income, and health conditions with PD to ensure fair service delivery.</p>","PeriodicalId":12980,"journal":{"name":"Health and Quality of Life Outcomes","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13020280/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146226632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Iryna Shakhnenko, Shushan Hovsepyan, Emily I Holthuis, Helen Bulbeck, Winette T A van der Graaf, Olga Husson
{"title":"Incorporating patients' input in the development and validation of patient-reported outcome measures in oncology: a comprehensive scoping review.","authors":"Iryna Shakhnenko, Shushan Hovsepyan, Emily I Holthuis, Helen Bulbeck, Winette T A van der Graaf, Olga Husson","doi":"10.1186/s12955-026-02500-4","DOIUrl":"10.1186/s12955-026-02500-4","url":null,"abstract":"","PeriodicalId":12980,"journal":{"name":"Health and Quality of Life Outcomes","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13020400/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146219578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tatiana Durão D'Avila Luz, Leonardo Gomes de Oliveira Luz, Bruno Barbosa Giudicelli, Arnaldo Tenório da Cunha Júnior, Elthon Allex da Silva Oliveira, Bruno Cleiton Macedo do Carmo, Geraldo de Albuquerque Maranhão Neto, Liliana Carina Pereira Baptista, Raul Agostinho Simões Martins
{"title":"Associations between physical activity and quality of life in university students during the COVID-19 pandemic.","authors":"Tatiana Durão D'Avila Luz, Leonardo Gomes de Oliveira Luz, Bruno Barbosa Giudicelli, Arnaldo Tenório da Cunha Júnior, Elthon Allex da Silva Oliveira, Bruno Cleiton Macedo do Carmo, Geraldo de Albuquerque Maranhão Neto, Liliana Carina Pereira Baptista, Raul Agostinho Simões Martins","doi":"10.1186/s12955-026-02495-y","DOIUrl":"10.1186/s12955-026-02495-y","url":null,"abstract":"<p><strong>Background/purpose: </strong>The present study investigated variance in overall quality of life in relation to a broad spectrum of correlates, including sociodemographic characteristics, health self-reports related to the COVID-19 pandemic, sedentary behavior, and habitual physical activity, as well as examined the relationship between habitual physical activity and quality of life domains in university students during the first year of the COVID-19 pandemic.</p><p><strong>Methods: </strong>This cross-sectional observational study was conducted with 4059 undergraduate students (1859 men). Data were collected between June and October 2020. The electronic questionnaire comprised four main domains: sociodemographic characteristics, self-reported health conditions related to the COVID-19 pandemic, sedentary behavior and physical activity level, and quality of life.</p><p><strong>Results: </strong>Students reported a mean score of 58.3 (± 21.2) for overall quality of life (males: 59.7 ± 21.0; females: 57.2 ± 21.4, p < 0.001). Male students exhibited significantly higher scores than female students across all quality of life domains, with the exception of the social domain (p > 0.05). Notably, a set of variables was associated with higher quality of life scores across both sexes including having private health insurance, sleeping between 7 h and 9 h per night, and engaging in moderate or high levels of physical activity. Students classified as physically active associated with better perception in all quality of life domains across both sexes.</p><p><strong>Conclusion: </strong>While these findings are consistent with the existing literature, they further underscore the importance of addressing the interplay of sociodemographic, lifestyle, and health-related factors in strategies aimed at improving quality of life in university students during lockdown.</p>","PeriodicalId":12980,"journal":{"name":"Health and Quality of Life Outcomes","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13011726/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146194522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alexandra Piltz, Clara Herta Spiller, Anja Zschieschang, Guido Fitze, Holger Muehlan, Jurek Schultz
{"title":"German translation, cultural adaptation and linguistic validation of the PedsQL healthcare satisfaction module.","authors":"Alexandra Piltz, Clara Herta Spiller, Anja Zschieschang, Guido Fitze, Holger Muehlan, Jurek Schultz","doi":"10.1186/s12955-026-02492-1","DOIUrl":"10.1186/s12955-026-02492-1","url":null,"abstract":"<p><p>BACKGROUND: Healthcare satisfaction (HCS) is a crucial patient-reported outcome that is essential for evaluating medical care quality from the patient’s viewpoint and may also significantly impact other patient-reported outcome measures. However, currently validated German instruments lack a generic focus, which is essential for treating various diagnoses in pediatric surgery contexts. This study presents the translation and cultural adaptation of the PedsQL Healthcare Satisfaction Generic Module (HCSGM) for Germany. METHODS: The PedsQL 3.0 HCSGM is a 24-item questionnaire assessing six dimensions: information, family inclusion, communication, technical skills, emotional needs, and overall satisfaction. After two independent forward translations and a back translation, a preliminary version was tested with caregivers of 10 patients who provided feedback using the thinking-aloud technique while completing the questionnaire. Interviews were analyzed using qualitative content analysis (QCA), leading to the final German version of the HCSGM. RESULTS: The initial consensus meeting after the forward translations identified five areas for improvement. The backward translation was approved with no further changes. QCA revealed ten major and nine minor issues, which resulted in ten modifications to item wordings, question-wording, verbal anchors of answer options, and layout during a second consensus meeting. Those modifications resulted in the final version also being approved by the original authors. CONCLUSION: The German version of the PedsQL HCSGM is now available to measure HCS, a crucial PROM for clinical research and patient management. While qualitative methods have been employed to ensure equivalence, further studies should evaluate psychometric properties. </p>","PeriodicalId":12980,"journal":{"name":"Health and Quality of Life Outcomes","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12955180/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146179347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Longitudinal validation of the GHQ-12 and PHQ-2 in Chilean social housing populations in urban regeneration contexts.","authors":"Gabriel González-Medina, Alejandra Vives","doi":"10.1186/s12955-026-02488-x","DOIUrl":"10.1186/s12955-026-02488-x","url":null,"abstract":"<p><p>BACKGROUND: Brief questionnaires have been applied in poor urban populations to monitor their mental health. Mental health outcomes encompass diverse symptoms that differ in cause and functional impact; however, most studies combine these symptoms as if they represented a single construct. Longitudinal validation of health instruments requires understanding the psychometric properties and causal structures between measurement points to distinguish measurement error from true change before interpreting intervention effectiveness. However, the longitudinal psychometric properties of the General Health Questionnaire (GHQ-12) and Patient Health Questionnaire (PHQ-2) in Latin American social housing populations remain unknown. This study assessed the dimensionality and longitudinal psychometric properties of these instruments in Chilean populations targeted by urban regeneration interventions. OBJECTIVE: To assess the longitudinal psychometric properties of the General Health Questionnaire (GHQ-12) and Patient Health Questionnaire (PHQ-2) in poor Chilean urban populations undergoing urban regeneration interventions. METHODS: We analyzed two waves of mental health data (6-month intervals) from 955 residents of social housing neighborhoods in Santiago and Viña del Mar, Chile. We evaluated item-level and scale-level statistics, confirmatory factor analysis, construct validity, test-retest reliability, and longitudinal measurement invariance. Following recent advances in causal inference methodology, we examined measurement error structures via directed acyclic graph principles to understand the causal implications of psychometric findings. RESULTS: Both instruments demonstrated good psychometric properties and construct validity. The three-factor GHQ-12 structure (dysphoria, social dysfunction, loss of confidence) showed an optimal fit (comparative fit index = 0.996, Tucker‒Lewis index = 0.992, root mean square error of approximation = 0.025). Dysphoria exhibited the strongest correlation with the PHQ-2 (r = 0.65) and highest temporal stability (0.60), whereas social dysfunction showed the lowest stability (0.48), suggesting differential sensitivity to environmental interventions. Evidence of a response shift emerged: while configural and metric invariance held across time, scalar invariance was violated (change in comparative fit index = 0.105), indicating systematic changes in item thresholds rather than true mental health changes. CONCLUSIONS: The GHQ-12 and PHQ-2 are reliable instruments for longitudinal mental health assessment in poor urban populations. However, scalar non-invariance suggests that residents recalibrate their mental health standards while urban regeneration begins, which has important implications for interpreting intervention effects. Future studies should incorporate measurement invariance testing and latent variable approaches when evaluating complex environmental interventions. </p>","PeriodicalId":12980,"journal":{"name":"Health and Quality of Life Outcomes","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12997820/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146179386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mengyuan He, Lin Wu, Wei Gu, Dongfa Liao, Benjing Song, Hongbao Hu, Lin Cui, YidaAmu, Shihong Li, Yingchao Tang, Jianxiang Long, Li Yin, Qingyun Xie, Wei Wang
{"title":"Psychometric evaluation and adaptability of the simplified Chinese version of HOOS-12 in patients undergoing total hip arthroplasty.","authors":"Mengyuan He, Lin Wu, Wei Gu, Dongfa Liao, Benjing Song, Hongbao Hu, Lin Cui, YidaAmu, Shihong Li, Yingchao Tang, Jianxiang Long, Li Yin, Qingyun Xie, Wei Wang","doi":"10.1186/s12955-026-02491-2","DOIUrl":"10.1186/s12955-026-02491-2","url":null,"abstract":"<p><p>INTRODUCTION: Considering the response burden of the full version of the HOOS scale, researchers developed a more concise HOOS-12 scale. Although the HOOS-12 has been verified to have good reliability, validity and responsiveness in most Western-country studies, it still needs further evaluation in other non-English populations. Therefore, our aim is to assess the content validity, internal consistency, structural validity, test-retest reliability, responsiveness, floor effect and ceiling effect of the Chinese version of HOOS-12 in the patient population whose native language is Chinese. The goal is to provide a high-quality evaluation tool for the global Chinese-using hip joint patient population, promote cross-cultural and cross-regional hip joint research, and ensure the comparability of the data. METHOD: Patients with chronic hip diseases scheduled for total hip arthroplasty were included in the study. Content validity was evaluated using expert review to assess item relevance. CFA was employed to validate the construct validity of the CHOO-12. Convergent and discriminant validity of the CHOOS-12 were assessed using the SF-36, OHS, and WOMAC scales as reference instruments. The first HOOS-12 scores were used to evaluate content validity, internal consistency, and structural validity. The second set of scores was utilized to assess test-retest reliability and ceiling/floor effects. The third set of scores was applied to evaluate responsiveness. RESULT: The CHOOS-12 demonstrated good content validity. No ceiling or floor effects were observed for the CHOOS-12 total scale or its pain, function, and quality of life subscales. The internal consistency among items was high for both the overall CHOOS-12 and all its subscales. CFA indicated satisfactory performance for the pain dimension, though the unidimensionality of the function and quality of life dimensions was challenged. The CHOOS-12 scale exhibited good convergent and discriminant validity. With overall ES and SRM values of 2.08 and 2.42 respectively, the CHOOS-12 also demonstrated good responsiveness. CONCLUSION: CHOOS-12 demonstrated good reliability and validity in this study. In terms of construct validity, the pain subscale performed well, although the unidimensionality of the PF and QOL subscales was challenged, the core items still had measurement potential. Future research needs to conduct further validation in larger and more diverse samples. </p>","PeriodicalId":12980,"journal":{"name":"Health and Quality of Life Outcomes","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12998062/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146179329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yiyun Shou, Jia Jia Lee, Janhavi Ajit Vaingankar, Mythily Subramaniam, Nan Luo
{"title":"Exploring the psychological well-being construct and validating the Comprehensive Inventory of Thriving in Singapore.","authors":"Yiyun Shou, Jia Jia Lee, Janhavi Ajit Vaingankar, Mythily Subramaniam, Nan Luo","doi":"10.1186/s12955-026-02484-1","DOIUrl":"10.1186/s12955-026-02484-1","url":null,"abstract":"<p><p>BACKGROUND: Positive psychological functions are associated with various health and life outcomes. This study examined the construct of psychological well-being in the multi-ethnic Singaporean population and evaluated the Comprehensive Inventory of Thriving (CIT) scale that captures 18 aspects of psychological well-being. METHOD: A two-wave survey study was carried out with 1349 community-dwelling Singaporean adults, of whom 562 completed the second wave. We compared factor structures that have been reported in other populations. The factor model was further tested for replicability in a subsequent household survey sample (N = 1756). RESULTS: A new higher-order factor model emerged in the Singaporean sample consisting of three dimensions: interpersonal well-being, individual well-being, and resistance to threats. The new structure demonstrated gender and age measurement invariance. CIT and the three dimensions had expected associations with mental health symptoms, work/study stress, and participants’ actual social support. The new higher-order factor model was replicated in the subsequent household survey sample. Finally, both CIT and its short form, the Brief Inventory of Thriving (BIT), showed convergent validity, reliability and test-retest reliability in the Singaporean population. CONCLUSIONS: CIT demonstrated some evidence of construct validity and reliability in the current large samples of Singaporean community-dwelling adults. BIT can be an efficient tool to assess and monitor population general well-being. </p>","PeriodicalId":12980,"journal":{"name":"Health and Quality of Life Outcomes","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13094012/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146165262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}