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Impact of a Clinical Decision Support System on the Efficiency and Effectiveness of Performing Medication Reviews in Community Pharmacies: A Randomized Controlled Trial.
IF 2.4 4区 医学
Healthcare Pub Date : 2024-12-09 DOI: 10.3390/healthcare12232491
Armin Dabidian, Florian Kinny, Melina Steichert, Sabina Schlottau, Anke Bartel, Holger Schwender, Stephanie Laeer
{"title":"Impact of a Clinical Decision Support System on the Efficiency and Effectiveness of Performing Medication Reviews in Community Pharmacies: A Randomized Controlled Trial.","authors":"Armin Dabidian, Florian Kinny, Melina Steichert, Sabina Schlottau, Anke Bartel, Holger Schwender, Stephanie Laeer","doi":"10.3390/healthcare12232491","DOIUrl":"https://doi.org/10.3390/healthcare12232491","url":null,"abstract":"<p><strong>Background: </strong>Clinical decision support systems (CDSSs) already support community pharmacists in conducting medication reviews (MRs) by identifying important information on interactions and suggesting clinical solutions. However, their impact in terms of quality and time savings is widely unexplored. The aim of our study was to investigate whether MRs are performed faster and better with or without using a CDSS.</p><p><strong>Methods: </strong>In a randomized controlled study with a cross-over design, 71 pharmacists performed a total of four MRs, two with and two without the use of a CDSS. The primary endpoint was defined as the time required for the MRs. The secondary endpoints were the number of predefined relevant drug-related problems (DRPs) detected and pharmacist satisfaction.</p><p><strong>Results: </strong>Without the use of a CDSS, pharmacists needed between 25.7% and 30.7% more time to perform a MR than with a CDSS. In addition, significantly more relevant DRPs were detected in the MRs with CDSS than without CDSS (70% vs. 50%; <i>p</i> = 0.0037). Furthermore, participants stated that they felt more confident using a CDSS for MRs than without.</p><p><strong>Conclusions: </strong>Our results demonstrate that MRs can be performed both faster and better when using a CDSS than without. Consequently, community pharmacists benefit from the use of CDSSs for MRs, as do patients in terms of their drug therapy safety.</p>","PeriodicalId":12977,"journal":{"name":"Healthcare","volume":"12 23","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142835362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Impact of Mood Disorders on Adherence, on Life Satisfaction and Acceptance of Illness-Cross-Sectional Observational Study.
IF 2.4 4区 医学
Healthcare Pub Date : 2024-12-09 DOI: 10.3390/healthcare12232484
Alicja Jeżuchowska, Anna Maria Cybulska, Kamila Rachubińska, Karolina Skonieczna-Żydecka, Artur Reginia, Mariusz Panczyk, Dorota Ćwiek, Elżbieta Grochans, Daria Schneider-Matyka
{"title":"The Impact of Mood Disorders on Adherence, on Life Satisfaction and Acceptance of Illness-Cross-Sectional Observational Study.","authors":"Alicja Jeżuchowska, Anna Maria Cybulska, Kamila Rachubińska, Karolina Skonieczna-Żydecka, Artur Reginia, Mariusz Panczyk, Dorota Ćwiek, Elżbieta Grochans, Daria Schneider-Matyka","doi":"10.3390/healthcare12232484","DOIUrl":"https://doi.org/10.3390/healthcare12232484","url":null,"abstract":"<p><p><b>Background:</b> Mood disorders are among the most prevalent and debilitating mental conditions in worldwide populations. The aim of this study was to identify the factors influencing life satisfaction, disease acceptance, and therapeutic adherence among people with mood disorders. <b>Methods</b>: This survey-based study included 103 people with mood disorders. It was performed using the author questionnaire, and standardized research tools, namely the Adherence to Refills and Medication Scale (ARMS), the Acceptance of Illness Scale (AIS), the Beck Depression Inventory (BDI), and the Satisfaction with Life Scale (SWLS). <b>Results:</b> The level of life satisfaction decreased with the increase in the severity of the depressive symptoms (<i>SE</i> = -0.665, <i>p</i> < 0.001). Mood disorder patients with more severe depressive symptoms had significantly higher scores on the adherence scale (<i>SE</i> = 0.290, <i>p</i> = 0.003). The patients with higher levels of depressive symptoms showed a lower level of acceptance of the disease. <b>Conclusions:</b> 1. The dosage of medications taken, and the severity of the depressive symptoms determine life satisfaction of people with mood disorders. 2. The respondents with a greater severity of depressive symptoms scored higher on the adherence scale, which means that they were more likely to be non-adherent to the treatment recommendations. The type of mood disorder may affect patient adherence. The subjects with bipolar disorder showed higher adherence and those with anxiety-depressive disorder showed a lower adherence than the patients with depression. 3. The subjects with more severe depressive symptoms showed a lower degree of acceptance of the disease.</p>","PeriodicalId":12977,"journal":{"name":"Healthcare","volume":"12 23","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142835488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
"Navigating Risk and Responsibility?": A Mixed-Methods Study Addressing Stigma and Well-Being Among Men Who Have 'Sex on Chems' with Other Men in the English Midlands.
IF 2.4 4区 医学
Healthcare Pub Date : 2024-12-08 DOI: 10.3390/healthcare12232479
Amanda Wilson, Iain R Williamson
{"title":"\"Navigating Risk and Responsibility?\": A Mixed-Methods Study Addressing Stigma and Well-Being Among Men Who Have 'Sex on Chems' with Other Men in the English Midlands.","authors":"Amanda Wilson, Iain R Williamson","doi":"10.3390/healthcare12232479","DOIUrl":"https://doi.org/10.3390/healthcare12232479","url":null,"abstract":"<p><strong>Background: </strong>Most research on 'Chemsex' has been conducted with gay, bi-sexual, and men who have sex with men (GBMSM) in large cities with well-established infrastructures. Therefore, this study aimed to explore the 'Chemsex' risks and responsibilities of GBMSM who lived outside of the queer metropolis. This study also aimed to understand how stigma and mental health present in the absence of a well-established community infrastructure.</p><p><strong>Methods: </strong>This study utilized mixed methods in Leicester, Leicestershire, and Rutland, a location in the East Midlands of England. The quantitative component consisted of a survey. The qualitative component comprised three case studies based on in-depth interviews, using interpretative phenomenological analysis.</p><p><strong>Results: </strong>Of the 123 survey respondents, 86% engaged in riskier sex during sessions and 35% no longer enjoyed sober sex. In the interviews, the three men balanced risk management and personal responsibility, positioning themselves as mature, considerate, and well-educated users. All were alienated by the term 'Chemsex'. The findings are considered using theoretical frameworks, or how discourses of 'moral threat' operate within the micro-politics of regulating GBMSM's pleasure and stigma.</p><p><strong>Conclusions: </strong>The complexities of understanding this practice for researchers and practitioners are discussed and recommendations are made for reframing education and support services for GBMSM.</p>","PeriodicalId":12977,"journal":{"name":"Healthcare","volume":"12 23","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142835286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Passive Smoking Is Associated with the Risk of Functional Bowel Disorders Among College Freshmen.
IF 2.4 4区 医学
Healthcare Pub Date : 2024-12-07 DOI: 10.3390/healthcare12232477
Jinlu Guo, Fan Du, Chaofan Duan, Can Chen, Jingze Yang, Xin Yang, Shi Liu, Tao Bai, Xiaohua Hou
{"title":"Passive Smoking Is Associated with the Risk of Functional Bowel Disorders Among College Freshmen.","authors":"Jinlu Guo, Fan Du, Chaofan Duan, Can Chen, Jingze Yang, Xin Yang, Shi Liu, Tao Bai, Xiaohua Hou","doi":"10.3390/healthcare12232477","DOIUrl":"https://doi.org/10.3390/healthcare12232477","url":null,"abstract":"<p><p><b>Background</b>: Functional bowel disorders (FBDs) have detrimental effects on young adults, but the risk factors were not fully explored. This study aimed to investigate the prevalence and potential risk factors of FBDs in college freshmen, including, in particular, the association between passive smoking and the risk and symptoms of FBDs. <b>Methods</b>: A cross-sectional study was conducted in September 2019 in freshmen of Huazhong University of Science and Technology with a random cluster sampling method. Validated questionnaires were voluntarily completed by participants. Rome IV criteria were applied for the diagnosis of FBDs. Univariate analysis and multivariate logistic regression analysis (Model 1: unadjusted; Model 2: adjusted for age and sex; Model 3: adjusted for age, sex, intake frequency of coffee and juice, regular exercise, total sedentary time, sleep quality, interpersonal relationship, and SLSI scores) were performed to determine the potential risk factors of FBDs. <b>Results</b>: A total of 3074 participants were included in this study, among whom 236 college freshmen were diagnosed with FBDs. There was a positive relationship between passive smoking and the risk of FBDs (crude odds ratio [OR] = 2.084, 95% confidence interval [CI]: 1.480, 2.936, Model 1; adjusted OR = 1.825, 95%CI: 1.245, 2.675, Model 3). Moreover, the symptoms of hard stool, exertion, and sensation of obstruction in defecation were more frequent in passive smokers than non-passive smokers among FBD patients. Meanwhile, diarrhea was comparable between passive smokers and non-passive smokers among FBD patients. <b>Conclusions</b>: In the present study, around 7.68% of college freshmen were found to have FBDs. Passive smoking was positively associated with the risk of FBDs. Furthermore, passive smoking was significantly associated with constipation-related symptoms rather than diarrhea among FBD patients.</p>","PeriodicalId":12977,"journal":{"name":"Healthcare","volume":"12 23","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142835498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of Urinary Incontinence in Female Professional Soccer Players by Category and Specific Position: A Comparative Study with a Control Group.
IF 2.4 4区 医学
Healthcare Pub Date : 2024-12-07 DOI: 10.3390/healthcare12232478
Julia M Sebastian-Rico, María Jesús Muñoz-Fernández, Luis Manuel Martínez-Aranda, África Calvo-Lluch, Manuel Ortega-Becerra
{"title":"Prevalence of Urinary Incontinence in Female Professional Soccer Players by Category and Specific Position: A Comparative Study with a Control Group.","authors":"Julia M Sebastian-Rico, María Jesús Muñoz-Fernández, Luis Manuel Martínez-Aranda, África Calvo-Lluch, Manuel Ortega-Becerra","doi":"10.3390/healthcare12232478","DOIUrl":"https://doi.org/10.3390/healthcare12232478","url":null,"abstract":"<p><strong>Background/objectives: </strong>Urinary incontinence (UI) significantly impacts quality of life, with varying prevalence in women depending on factors such as age, childbirth, and type of sport practiced. This study compared the prevalence, types, and severity of urinary incontinence (UI) between professional female soccer players and sedentary students, analyzing its relation to playing position and competitive level.</p><p><strong>Methods: </strong>A descriptive, observational, and analytical cross-sectional study was conducted, assessing the prevalence, severity, and types of UI among 235 nulliparous professional female soccer players (experimental group, EG) and 252 sedentary female students (control group, CG). Data were collected using the short version of the International Consultation on Incontinence Questionnaire (ICIQ-SF). Statistical analyses included Fisher's exact test to compare prevalence rates.</p><p><strong>Results: </strong>The findings revealed that 35% of soccer players and 31% of sedentary students reported experiencing UI. Stress urinary incontinence (SUI) was the most prevalent type in both groups, affecting 26% of soccer players and 14% of sedentary students, while mixed UI was more frequent among sedentary women (17%) (<i>p</i> < 0.05). No significant differences were observed in UI prevalence based on playing position or competitive level (<i>p</i> ≥ 0.05). However, female soccer players exhibited a significantly higher prevalence of UI during physical exertion or exercise compared to the control group (<i>p</i> ≤ 0.001), suggesting that high-impact sports may contribute to pelvic floor dysfunction. Additionally, 23.8% of soccer players reported mild-to-moderate UI severity.</p><p><strong>Conclusion: </strong>Female soccer players showed higher UI prevalence during exercise, underscoring the need for targeted interventions like pelvic floor training.</p>","PeriodicalId":12977,"journal":{"name":"Healthcare","volume":"12 23","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142835535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vulnerability: An Interpretive Descriptive Study of Personal Support Workers' Experiences of Working During the COVID-19 Pandemic in Ontario, Canada. 脆弱性:对加拿大安大略省 COVID-19 大流行期间个人支持工作者工作经历的解释性描述研究。
IF 2.4 4区 医学
Healthcare Pub Date : 2024-12-06 DOI: 10.3390/healthcare12232474
Upasana Panda, Monique Lanoix, Rebecca Gewurtz, Sandra Moll, Evelyne Durocher
{"title":"Vulnerability: An Interpretive Descriptive Study of Personal Support Workers' Experiences of Working During the COVID-19 Pandemic in Ontario, Canada.","authors":"Upasana Panda, Monique Lanoix, Rebecca Gewurtz, Sandra Moll, Evelyne Durocher","doi":"10.3390/healthcare12232474","DOIUrl":"https://doi.org/10.3390/healthcare12232474","url":null,"abstract":"<p><strong>Background/objectives: </strong>Personal support workers (PSWs) are important healthcare workers providing essential services to thousands of Canadians. PSWs face many challenges that were exacerbated in the context of the COVID-19 pandemic. In this study we explore experiences of PSWs working through the pandemic in Ontario long-term care (LTC) homes by focusing on the vulnerability of such workers.</p><p><strong>Methods: </strong>An interpretive description approach was adopted. Eleven PSWs working in LTC homes in an urban center in Ontario participated in semi-structured interviews between January and May 2022. Thematic analysis of the transcripts was informed by concepts of vulnerability.</p><p><strong>Results: </strong>The results suggest that PSWs experienced inherent, situational, and pathogenic vulnerability. Inherent vulnerability was experienced in relation to risks of contracting the coronavirus working in person with residents, and of experiencing physical and psychological distress in relation to challenging interactions with staff, residents and their superiors. Situational vulnerability was experienced in relation to demanding workloads, which were intensified in the context of the pandemic. Participants expressed feeling undervalued, unappreciated, and disrespected, reflecting experiences of pathogenic vulnerability. The narratives shared by PSWs highlighted how the COVID-19 pandemic added new, and magnified pre-existing, challenges and vulnerability, affecting their health and well-being.</p><p><strong>Conclusions: </strong>Understanding risks faced by PSWs in LTC settings is crucial for developing targeted interventions and policies to support PSWs' health and well-being, mitigate factors that contribute to their vulnerability and promote the long-term sustainability of this caregiving workforce, ultimately enhancing the quality of care provided to residents in LTC facilities.</p>","PeriodicalId":12977,"journal":{"name":"Healthcare","volume":"12 23","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142834945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Glucose Metabolism Disorders and Parkinson's Disease: Coincidence or Indicator of Dysautonomia?
IF 2.4 4区 医学
Healthcare Pub Date : 2024-12-06 DOI: 10.3390/healthcare12232462
Tomasz Chmiela, Przemysława Jarosz-Chobot, Agnieszka Gorzkowska
{"title":"Glucose Metabolism Disorders and Parkinson's Disease: Coincidence or Indicator of Dysautonomia?","authors":"Tomasz Chmiela, Przemysława Jarosz-Chobot, Agnieszka Gorzkowska","doi":"10.3390/healthcare12232462","DOIUrl":"https://doi.org/10.3390/healthcare12232462","url":null,"abstract":"<p><p><b>Background:</b> Parkinson's disease (PD) and type 2 diabetes mellitus (T2DM) are both age-related diseases. Evidence from recent studies suggests a link between them. The existence of an interaction between autonomic nervous system dysfunction and the dysregulation of glucose metabolism is one of the proposed mechanisms to explain the complicated relationship between these diseases. The aims of this study are to assess the incidence of glycemic dysregulation in people with PD and to identify clinical factors that may predispose patients with PD to the occurrence of metabolic disturbances. <b>Methods:</b> In total, 35 individuals diagnosed with PD and 20 healthy control subjects matched in terms of age and gender participated in a study consisting of clinical and biometric assessments along with 14 days of continuous glucose monitoring (CGM) using the Freestyle Libre system. In the group of patients with PD, a comparative analysis was performed between patients with and without autonomic dysfunction. The severity of autonomic dysfunction was assessed using the SCOPA-AUT. <b>Results</b>: Participants diagnosed with PD demonstrated a trend toward lower morning glucose levels compared to the control group. PD patients with autonomic symptoms had greater glucose variability and a deeper trend toward lower glucose levels in the mornings. The presence of autonomic dysfunction, especially orthostatic hypotension and micturition disturbance, and the severity of autonomic symptoms were associated with greater glycemic variability. <b>Conclusions</b>: The occurrence of autonomic disorders in the course of Parkinson's disease predisposes patients to more profound glycemic dysregulation.</p>","PeriodicalId":12977,"journal":{"name":"Healthcare","volume":"12 23","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142834928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Effects of Motivational Interviews About Activities of Daily Living on Physical Adjustment and Quality of Life in Elderly Total Knee Arthroplasty Patients: A Randomised-Controlled Trial.
IF 2.4 4区 医学
Healthcare Pub Date : 2024-12-06 DOI: 10.3390/healthcare12232472
Gizem Kubat Bakir, Sonay Göktas
{"title":"The Effects of Motivational Interviews About Activities of Daily Living on Physical Adjustment and Quality of Life in Elderly Total Knee Arthroplasty Patients: A Randomised-Controlled Trial.","authors":"Gizem Kubat Bakir, Sonay Göktas","doi":"10.3390/healthcare12232472","DOIUrl":"https://doi.org/10.3390/healthcare12232472","url":null,"abstract":"<p><p>In old age, knee osteoarthritis is a common disease that reduces mobility. Total knee arthroplasty (TKA) is, in fact, a very important surgery to treat severe knee osteoarthritis. This study aimed to analyse the effect of motivational interviewing (MI) on physical adjustment and quality of life among old patients after TKA. Self-assessment forms were applied before and after the intervention using the functional assessment form and SF-36 Quality of Life Questionnaire in both groups: the intervention group who received MI targeted at daily living activities and the control group who received usual care within a randomised controlled trial that included 70 participants. The results we obtained showed significantly higher functional capacity scores and QOLs among those who underwent MI than those who did not have this additional support, while showing strong adjusted mean differences between two interventions that indicate this effect size difference. There was a notable increase in SF-36 scores from 51.14 to 85.77 which was much higher than the control's rise from 45.97 to 59.46. Therefore, these findings suggest that many elderly people can greatly improve their health status after TKA with MI as it offers an opportunity for effective recovery during the post-operative period, especially among older adults. Therefore, it can be used as an efficient method included in standard routines after operations so that results are improved and patients' satisfaction levels also increased simultaneously too.</p>","PeriodicalId":12977,"journal":{"name":"Healthcare","volume":"12 23","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142835276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hemodynamic Effects of SGLT2 Inhibitors in Patients with and Without Diabetes Mellitus-A Narrative Review.
IF 2.4 4区 医学
Healthcare Pub Date : 2024-12-06 DOI: 10.3390/healthcare12232464
Roxana Brata, Andrei Vasile Pascalau, Ovidiu Fratila, Ioana Paul, Mihaela Mirela Muresan, Andreea Camarasan, Tiberia Ilias
{"title":"Hemodynamic Effects of SGLT2 Inhibitors in Patients with and Without Diabetes Mellitus-A Narrative Review.","authors":"Roxana Brata, Andrei Vasile Pascalau, Ovidiu Fratila, Ioana Paul, Mihaela Mirela Muresan, Andreea Camarasan, Tiberia Ilias","doi":"10.3390/healthcare12232464","DOIUrl":"https://doi.org/10.3390/healthcare12232464","url":null,"abstract":"<p><p><b>Background</b>: The current review aims to present the beneficial effects of SGLT2 inhibitors (dapagliflozin and empagliflozin) on several hemodynamic parameters such as blood pressure, filtration pressure at the level of the glomerular capillaries, and the improvement of the preload and afterload of heart muscle. In order to stop chronic kidney disease (CKD) from progressing, SGLT2 inhibitors have become an important disease-modifying treatment. <b>Materials and methods</b>: Recent clinical studies have shown the success of these drugs in treating heart failure, reducing the risk of cardiovascular events, hospitalization, and mortality. <b>Results</b>: The hemodynamic effects of SGLT2 inhibitors include a diuretic effect, due to reduced sodium reabsorption. Also, at this level, numerous studies have confirmed the beneficial effect of dapagliflozin in patients with chronic kidney disease, associated with a 44% reduced risk of progression in this pathology. SGLT2 inhibitors are associated with a reduction in blood pressure and weight loss, because of their diuretic effect, especially empagliflozin, which can explain the beneficial effects in patients with heart failure. In addition, mainly empagliflozin reduces stiffness and arterial resistance. <b>Conclusions</b>: Although the exact mechanism of action is unknown, SGLT2 inhibitors reduce the interstitial volume by blocking the tubular reabsorption of glucose. This leads to reduced blood pressure and enhanced endothelial function. Consequently, there have been improvements in hospitalization and fatality rates. Because of their beneficial effects, these medications have been guidelines for managing heart failure and chronic kidney disease.</p>","PeriodicalId":12977,"journal":{"name":"Healthcare","volume":"12 23","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142835278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Health Promotion in Glycemic Control and Emotional Well-Being of People with Type 1 Diabetes Mellitus: A Systematic Review and Meta-Analysis.
IF 2.4 4区 医学
Healthcare Pub Date : 2024-12-06 DOI: 10.3390/healthcare12232461
Miguel Garrido-Bueno, Manuel Pabón-Carrasco, Nerea Jiménez-Picón, Rocío Romero-Castillo
{"title":"Health Promotion in Glycemic Control and Emotional Well-Being of People with Type 1 Diabetes Mellitus: A Systematic Review and Meta-Analysis.","authors":"Miguel Garrido-Bueno, Manuel Pabón-Carrasco, Nerea Jiménez-Picón, Rocío Romero-Castillo","doi":"10.3390/healthcare12232461","DOIUrl":"https://doi.org/10.3390/healthcare12232461","url":null,"abstract":"<p><strong>Background/objectives: </strong>Structured therapeutic patient education is the key to improving biopsychosocial outcomes in people with type 1 diabetes mellitus. This study aimed to determine the effects of structured therapeutic education on glycemic control and emotional well-being in people with type 1 diabetes mellitus.</p><p><strong>Methods: </strong>This is a systematic review with a meta-analysis (PROSPERO ID: CRD42023390079). Searches were performed in Scopus, MEDLINE, Web of Science, CINAHL, APA PsycInfo, APA PsycArticles, and the Psychology Database (June-August 2024). The eligibility criteria included randomized controlled trials published in English or Spanish within the past 10 years. Data extraction and risk of bias evaluations were independently conducted by two reviewers. The outcomes analyzed included glycated hemoglobin, time in range, emotional well-being, self-management behaviors, and adherence to treatment. Meta-analyses were performed using RevMan with random and fixed effects models.</p><p><strong>Results: </strong>Seventeen studies met the eligibility criteria. There was a significant improvement in glycemic control, stress, anxiety, and treatment satisfaction, although the results for the other emotional outcomes were mixed.</p><p><strong>Conclusions: </strong>Structured therapeutic patient education improves glycemic control and selected emotional outcomes in individuals with type 1 diabetes mellitus. Further trials are needed to refine the characteristics of the intervention and broaden the applicability of the findings to diverse populations.</p>","PeriodicalId":12977,"journal":{"name":"Healthcare","volume":"12 23","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142835257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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