HautarztPub Date : 2022-02-01Epub Date: 2022-01-14DOI: 10.1007/s00105-021-04935-w
Carmen Maria Salavastru, Alexandra-Irina Butacu, Klaus Fritz, Seher Eren, George-Sorin Tiplica
{"title":"[Benign skin neoplasms in children].","authors":"Carmen Maria Salavastru, Alexandra-Irina Butacu, Klaus Fritz, Seher Eren, George-Sorin Tiplica","doi":"10.1007/s00105-021-04935-w","DOIUrl":"https://doi.org/10.1007/s00105-021-04935-w","url":null,"abstract":"<p><p>There are many different types of skin neoplasms in children and most are benign. Dermatologists should be able to differentiate between the various types of benign skin neoplasms and be able to recommend optimal treatment to concerned patients. Surgical removal of benign skin neoplasms is often the only treatment option. The aim of this paper is to provide a general overview of epidermal lesions (e.g., inflammatory linear verrucous epidermal nevus [ILVEN], nevus sebaceous), tumors of the epidermal appendages (e.g. pilomatrixoma), cutaneous neoplasms (e.g. angiofibroma), fibromatoses (e.g., knuckle pads), tumors comprised of fat, muscle, or bone tissue (e.g., osteoma cutis, subungual exostosis), epidermal cysts and pseudocysts, and pathologic fibrosis reactions after dermal injury (keloid). Scientific data are scarce and only in the last decade has it been possible to perform histopathological examinations and genetic studies together with detailed phenotyping to gain new understanding of the pathogenetic mechanisms.</p>","PeriodicalId":12970,"journal":{"name":"Hautarzt","volume":"73 2","pages":"127-137"},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39697644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HautarztPub Date : 2022-02-01Epub Date: 2021-12-14DOI: 10.1007/s00105-021-04931-0
Jeta Demiri, Miriam Abdo, Athanasios Tsianakas
{"title":"[Erythrodermic psoriasis after COVID-19].","authors":"Jeta Demiri, Miriam Abdo, Athanasios Tsianakas","doi":"10.1007/s00105-021-04931-0","DOIUrl":"https://doi.org/10.1007/s00105-021-04931-0","url":null,"abstract":"<p><p>We present a clinical case of a patient with acutely exacerbated erythrodermic psoriasis vulgaris after symptomatic infection with SARS-CoV‑2 (severe acute respiratory syndrome coronavirus 2). Various factors are already known that can lead to an exacerbation of psoriasis, such as drugs or infections with, for example, streptococcus. An association between psoriasis and an infection with SARS-CoV‑2 has been described so far in individual case reports, in which, however, drug treatment with for example hydroxychloroquine, a known trigger of psoriasis, often took place. Later cases of exacerbation of psoriasis, partly as pustular psoriasis have been published also without drug induction. However we present for the first time a case of erythrodermic psoriasis triggered by COVID-19 (coronavirus disease 2019) without an obvious drug trigger.</p>","PeriodicalId":12970,"journal":{"name":"Hautarzt","volume":"73 2","pages":"156-159"},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670040/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39723458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HautarztPub Date : 2022-01-01Epub Date: 2021-11-30DOI: 10.1007/s00105-021-04914-1
S Wolf, A Kis, J Augustin
{"title":"[Methods for analysing spatial data : Using the example of skin cancer prevalence in Germany].","authors":"S Wolf, A Kis, J Augustin","doi":"10.1007/s00105-021-04914-1","DOIUrl":"https://doi.org/10.1007/s00105-021-04914-1","url":null,"abstract":"<p><strong>Background: </strong>Studies show a spatial variation in skin cancer frequencies, but the causes have not been fully understood. When analysing spatial patterns and correlations, different approaches need to be considered, as the data have special features due to their spatial structure.</p><p><strong>Aim of the study: </strong>Why the spatial consideration of skin cancer frequencies is important at all, and which methods of analysis are useful is considered in more detail in this article. The article provides an introduction and overview of statistical methods that are important for the spatial analysis of skin cancer frequencies.</p><p><strong>Materials and methods: </strong>At first it is shown which descriptive methods, such as statistical smoothing, can be applied. Next, spatial cluster and regression analyses will be discussed. Testing for spatial autocorrelation will be considered.</p><p><strong>Results: </strong>In particular, the spatial dependence of the data on neighbouring regions, which if ignored can lead to biased estimates, is of particular importance in the analysis of spatial data and requires special spatial analysis methods.</p><p><strong>Discussion: </strong>This article provides an introduction and overview of statistical methods relevant to the spatial analysis of skin cancers.</p>","PeriodicalId":12970,"journal":{"name":"Hautarzt","volume":"73 1","pages":"15-20"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39790648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HautarztPub Date : 2022-01-01Epub Date: 2021-11-29DOI: 10.1007/s00105-021-04915-0
J Augustin, M Sander, R Bei der Kellen, M Augustin
{"title":"[Analysis of the skin cancer incidence in Hamburg].","authors":"J Augustin, M Sander, R Bei der Kellen, M Augustin","doi":"10.1007/s00105-021-04915-0","DOIUrl":"https://doi.org/10.1007/s00105-021-04915-0","url":null,"abstract":"<p><strong>Background: </strong>The aim of health geographical research is to identify regional variations in health and care and their causes. Regional differences are also evident in skin cancer incidence, but knowledge about small-scale, inner-city variations is not yet available.</p><p><strong>Objectives: </strong>How can the inner-city variations in skin cancer incidence in Hamburg, Germany, be described and how can initial indications of their causes be identified?</p><p><strong>Methods: </strong>The study area is the city of Hamburg and the data source is the Hamburg City Health Study with N = 10,000 persons aged 45-74 years. Descriptive methods are used to characterise the regional variation in skin cancer prevalence adjusted for age and sex. A correlation analysis provides information on possible associations with sociodemographic conditions in the city districts and district clusters.</p><p><strong>Results: </strong>Skin cancer prevalence varies within the urban area with high prevalences (maximum 13.8%) in the north-east and south-west of Hamburg. Weak to medium correlations with selected sociodemographic variables are found. For example, the higher the living space per inhabitant (r = 0.35), the higher the skin cancer prevalence in the district.</p><p><strong>Conclusions: </strong>The Hamburg City Health Study shows regional and inner-city disparities and possible associations between skin cancer prevalence and local sociodemographic conditions. However, further and methodologically more extensive studies are necessary in order to make detailed statements.</p>","PeriodicalId":12970,"journal":{"name":"Hautarzt","volume":"73 1","pages":"21-26"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39675840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HautarztPub Date : 2022-01-01Epub Date: 2022-01-12DOI: 10.1007/s00105-021-04920-3
Julie Kind
{"title":"[Twenty years as editor-in-chief of the journal Der Hautarzt-the editorial board and editorial office bid farewell to Professor Thomas Ruzicka].","authors":"Julie Kind","doi":"10.1007/s00105-021-04920-3","DOIUrl":"https://doi.org/10.1007/s00105-021-04920-3","url":null,"abstract":"","PeriodicalId":12970,"journal":{"name":"Hautarzt","volume":"73 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39903199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HautarztPub Date : 2022-01-01Epub Date: 2021-11-23DOI: 10.1007/s00105-021-04918-x
S Ziehfreund, L Tizek, A Zink
{"title":"[Web search data as health data? : Geographic differences, temporal trends, and topics of interest from internet search engine analyses in Germany].","authors":"S Ziehfreund, L Tizek, A Zink","doi":"10.1007/s00105-021-04918-x","DOIUrl":"10.1007/s00105-021-04918-x","url":null,"abstract":"<p><strong>Background: </strong>Limited timely, cost-effective, and regional availability of healthcare data is considered one of the limiting factors for timely analyses in the field of health services research and thus for healthcare delivery to the general population. Thus, Internet search engine analyses are coming into focus in this context.</p><p><strong>Objectives: </strong>What contribution can data on the volume of Internet searches for various diseases make to the health care of the German population? Where is the potential and where are the limitations?</p><p><strong>Methods: </strong>A review of the current literature and a selective overview of Internet search engine analyses of dermatological, allergological, and infectious diseases published in the last 4 years in Germany were performed.</p><p><strong>Results: </strong>By analyzing web search data, temporal developments such as seasonality, months with the highest interest, and geographical differences can be mapped at the national, state (Bundesländer), and city level and major points of interest (e.g., skin cancer of the eye or anal itching) regarding a certain health topic can be identified. In addition, some studies were able to show correlations between search volume and external factors (e.g., temperature, care structure) and to registered cases (e.g., skin cancer, Lyme disease).</p><p><strong>Conclusion: </strong>Web search data, given the limitations noted, are able to directly provide spatiotemporal mapping regarding the needs of the Internet-using population. They are particularly useful in situations where traditional health data are limited or unavailable.</p>","PeriodicalId":12970,"journal":{"name":"Hautarzt","volume":"73 1","pages":"53-60"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8609262/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39650788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HautarztPub Date : 2022-01-01Epub Date: 2021-06-16DOI: 10.1007/s00105-021-04835-z
F Mitri, A Enk, F Toberer
{"title":"[Axillary skin-colored papules in a young woman].","authors":"F Mitri, A Enk, F Toberer","doi":"10.1007/s00105-021-04835-z","DOIUrl":"https://doi.org/10.1007/s00105-021-04835-z","url":null,"abstract":"","PeriodicalId":12970,"journal":{"name":"Hautarzt","volume":"73 1","pages":"86-87"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s00105-021-04835-z","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39241490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HautarztPub Date : 2022-01-01Epub Date: 2022-01-12DOI: 10.1007/s00105-021-04919-w
M Augustin, J Augustin
{"title":"[Why knowledge about geographics is also helpful in medicine].","authors":"M Augustin, J Augustin","doi":"10.1007/s00105-021-04919-w","DOIUrl":"https://doi.org/10.1007/s00105-021-04919-w","url":null,"abstract":"","PeriodicalId":12970,"journal":{"name":"Hautarzt","volume":"73 1","pages":"4"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39903200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HautarztPub Date : 2022-01-01Epub Date: 2021-10-04DOI: 10.1007/s00105-021-04895-1
Matthias Augustin, Claudia Garbe, Gefion Girbig, Klaus Strömer, Natalia Kirsten
{"title":"[Epidemiology of scabies in Germany: multisource analysis of primary and secondary data].","authors":"Matthias Augustin, Claudia Garbe, Gefion Girbig, Klaus Strömer, Natalia Kirsten","doi":"10.1007/s00105-021-04895-1","DOIUrl":"https://doi.org/10.1007/s00105-021-04895-1","url":null,"abstract":"<p><strong>Background: </strong>Scabies is one of the most common and, in terms of burden of disease, one of the most significant skin diseases worldwide. In Germany, an increase in cases is currently being discussed, for which reliable data have been lacking until now.</p><p><strong>Objectives: </strong>The goal is to clarify the prevalence and treatment of scabies in Germany.</p><p><strong>Materials and methods: </strong>Multisource analyses of treatment data from a nationwide statutory health insurance company, the Federal Statistical Office and company skin screenings.</p><p><strong>Results: </strong>In Germany, the number of cases of scabies has been rising since 2009 and especially since 2014. In the outpatient setting, there was an increase of 52.8% to around 128,000 treatment cases between 2010 and 2015. Currently, more than 11,000 inpatient cases are documented annually in Germany with scabies as the main diagnosis (ICD-10 B86). The increase between 2010 and 2016 was about 306%. The main outpatient specialist groups providing care are dermatologists and general practitioners, while in the inpatient sector treatment is provided by departments of dermatology, paediatrics and internal medicine.</p><p><strong>Conclusion: </strong>Due to the aforementioned development of prevalence and incidence, the need for care will remain at a high level in the future, which suggests an increased need for education and early detection.</p>","PeriodicalId":12970,"journal":{"name":"Hautarzt","volume":"73 1","pages":"61-66"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755673/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39483520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HautarztPub Date : 2022-01-01Epub Date: 2022-01-05DOI: 10.1007/s00105-021-04924-z
Jana Dorothea Albrecht, Jan Peter Nicolay
{"title":"[Current therapeutic options in Mycosis fungoides and Sézary syndrome].","authors":"Jana Dorothea Albrecht, Jan Peter Nicolay","doi":"10.1007/s00105-021-04924-z","DOIUrl":"https://doi.org/10.1007/s00105-021-04924-z","url":null,"abstract":"<p><p>Driven by the approval of new targeted therapies, significant progress has been made in recent years in the clinical management of cutaneous T‑cell lymphomas. Although there are no curative treatment options for cutaneous T‑cell lymphomas, response rates are often encouraging, in particular when using combination therapies. The decision for the appropriate form of treatment depends on the specific diagnosis, disease stage, and the history of prior therapies. This article provides a comprehensive overview of current treatment options in mycosis fungoides and Sézary syndrome, based on the recently published, revised German S2k guidelines on cutaneous lymphomas (update 2021). In addition, we present promising, yet-to-be-approved therapies that at least in part can be already used off-label in clinical practice today.</p>","PeriodicalId":12970,"journal":{"name":"Hautarzt","volume":"73 1","pages":"75-85"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39901387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}