Headache Medicine最新文献

{"title":"Trends in physiopathology research of primary headaches over the last 50 years","authors":"R. Arruda, C. Bordini","doi":"10.48208/headachemed.2022.supplement.27","DOIUrl":"https://doi.org/10.48208/headachemed.2022.supplement.27","url":null,"abstract":"Introduction\u0000The headache field, mainly migraine, is passing through a transformative era of new treatments. These breakthroughs would not be possible without the evolving knowledge on mechanisms of headaches. However, there are still unmet needs for headaches' understanding and treatments.\u0000Objectives\u0000Assess whether there is a trend in the number of publications regarding physiopathology of each primary headache disorders (PHD) in the past 50 years. Secondarily, we aimed to evaluate how the SARS-CoV-2 pandemics impacted on physiopathology research of PHD.\u0000Methods\u0000PHD were divided hierarchically in first- and second-digit, according to ICHD-3 criteria. PubMed database was searched using both the name of the PHD and MeSH terms related to physiopathology. Each search yielded the number of publications for a determined PHD along the period selected (1971-2021). Data were retrieved and separated in two groups: a) per decades (1971-2020); and b) per year (2011-2021). Ratios between every two timepoints in each group were calculated, as well as a total ratio for the whole interval.\u0000Results\u0000Either divided per decades, or divided annually for the last 10 years, migraine had the highest absolute number of pathophysiology publications, significantly above the other PHD.\u0000Divided per decades, with exception of tension-type headache (TTH), all the other PHD groups have increased their number of publications over time. Meanwhile, TTH in the last decade decreased the total number of mechanisms research.\u0000The number of papers published in 2020 was lower than in 2019 for TTH, trigeminal autonomic cephalalgias (TACs) and group 4 \"other PHD\" (4.OPHD), migraine kept practically the same number.\u0000Conclusion\u0000There is a clear disparity in the number of publications on mechanisms of each PHD, being migraine well above TTH, TACs and 4.OPHD.\u0000As expected, the recent COVID pandemics has clearly impaired pathophysiologic research in the headache field.\u0000Keywords: Headache, Migraine, Mechanisms, Physiopathology, Research.","PeriodicalId":12925,"journal":{"name":"Headache Medicine","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76123572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intracranial hypertension associated with treatment of acute promyelocytic leukemia with all-trans retinoic acid (ATRA): a case report","authors":"T. Alvarenga, P. Sousa-Santos, P. Pozzobon, Itamar Meireles Santos, Ana Beatriz Baston, I. Teixeira","doi":"10.48208/headachemed.2022.supplement.47","DOIUrl":"https://doi.org/10.48208/headachemed.2022.supplement.47","url":null,"abstract":"Case presentation \u0000Female, 18 years-old, without relevant family history, referred to Neurology by Hematology for headache. 3 years ago, she was diagnosed with Acute Promyelocytic Leukemia (APL) currently on maintenance therapy with All-Trans Retinoic Acid (ATRA). The patient reports that in all previous cycles presented headache with the following characters: one-side temporal location, pulsating quality, moderate intensity, with nausea and vomiting, photophobia and phonophobia, uncertain duration, with simple analgesics response. In the current cycle, she relates continuous pain, severe intensity and unresponsive to medication. On examination, there were no focal neurological findings and on funduscopic examination there was no papilledema. MRI and laboratorial tests were normal. Cerebrospinal fluid (CSF) opening pressure was 35 cmH2O, no other alterations. 15 milliliters of CSF were removed, with a closing pressure of 25 cmH2O. A hypothesis of Intracranial Hypertension associated with use of ATRA was made. Afterwards, there was important improvement of the headache, with residual pain of mild intensity. Therefore, Acetazolamide was started at a dose of 250 milligrams every 12 hours with complete resolution of symptoms. \u0000  \u0000Discussion \u0000Acute myeloid leukemia (AML) comprises a heterogeneous group of aggressive blood cell cancers that arise from clonal expansion of malignant hematopoietic precursor cells in the bone marrow. Acute promyelocytic leukemia (APL) is a biologically and clinically distinct variant of AML. APL is classified as acute promyelocytic leukemia with PML-RARA. The cytogenetic hallmark of APL is a translocation involving RARA, the retinoic acid receptor alpha locus on chromosome 17. Without treatment, APL is the most malignant form of AML, with a median survival of less than one month. \u0000(To see the complete abstract, please, check out the PDF).","PeriodicalId":12925,"journal":{"name":"Headache Medicine","volume":"89 2-3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78154123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of cervical muscle strength in women with migraine stratified by the report of neck pain","authors":"Milena Dietrich D. Rosa, Amanda Rodrigues, M. M. Bragatto, M. Bigal, F. Dach, L. Florêncio, D. Bevilaqua-Grossi","doi":"10.48208/headachemed.2022.supplement.7","DOIUrl":"https://doi.org/10.48208/headachemed.2022.supplement.7","url":null,"abstract":"Introduction\u0000Individuals with migraine may have associated cervical musculoskeletal dysfunctions that may influence muscle function ¹,², but we still do not know if the alteration in muscle strength can predict the magnitude of this relationship or if the presence of pain during the tests can influence these results. Therefore, evaluating the muscle strength of migraine patients and the report of pain during the test can elucidate this relationship.\u0000Objective\u0000To clarify the relationship between pain reporting and cervical maximum isometric voluntary contraction (MVIC) in migraine individuals with and without neck pain, neck pain and controls.\u0000Methods\u0000We selected 100 women aged between 18 and 55 years, stratified into 4 groups: asymptomatic controls (n=25), neck pain (n=25), migraine (n=25), and migraine with neck pain (n=25). Patients were diagnosed by a neurologist according to the International Classification of Headache Disorders – III edition, whereas neck pain was included through self-report of chronic neck pain for at least 3 months (mild disability according to the Neck Disability Index). Clinical and demographic data were collected from the participants and they performed the Maximal isometric voluntary contractions (MIVC) test to verify cervical muscle strength for flexion and extension. The analyzes were performed following the division of the four groups by the ANOVA test using software version 9.4 (SAS Institute, Cary, NC, USA).\u0000Results\u0000A higher proportion of participants with migraine and neck pain (44%) and neck pain alone (56%) reported flexion test-induced neck pain compared to the control group (0% p<0.01), and neck pain Test-induced headache was more commonly reported in those with migraine (28%) and migraine with neck pain (28%) vs controls (0% p<0.05). (To see the complete abstract, please, check out the PDF).\u0000 ","PeriodicalId":12925,"journal":{"name":"Headache Medicine","volume":"353 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80084544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of sleep, pain and anxiety correlation in individuals with TMD: an analytic transversal study","authors":"Renata Paranhos, Lúcia Silvestre, R. Fernandes, Carina Ramos, Valdir Luna da Silva, R. Matos, Maria Cristina Ramos Vilela","doi":"10.48208/headachemed.2022.supplement.42","DOIUrl":"https://doi.org/10.48208/headachemed.2022.supplement.42","url":null,"abstract":"Introduction \u0000Temporomandibular disorder (TMD) is a pathology of the stomatognathic system, considered the main cause of non-dental orofacial pain.    Several signs and symptoms are present in the face from this pathology, and among them, there is the possibility of pain in the joint and associated regions.  \u0000Pain is defined by International Association Study of Pain as an unpleasant sensory and emotional experience associated with, or resembling that associated with, actual or potential tissue damage. Although it relates to adaptive processes, it can cause adverse effects on social and psychological function and well-being, influenced to different degrees by biological, psychological and social factors. Individuals with chronic pain, further to the pains, have oscillation in their emotional behaviors and sleep disturbances.  \u0000The anxiety and depression in the pathogenesis of temporomandibular disorders have been investigated since the entry of Research Diagnostic Criteria (RDC) for TMD in 1992, approached in Axis II of this instrument. Studies indicate that the health of the individual and quality of life are influenced negatively by the pain and/or for the stress caused by TMD, which can compromise daily activities, cognitive and affective balance, the physical activities and sleep. \u0000  As shown above, TMD is considered an important health problem nowadays, and is also important to consider the psychological aspects related to it and the impacts on the quality of the individuals affected by this disorder.  \u0000Objective \u0000The aim of this study is to analyze the correlation of sleep, pain and anxiety in individuals with TMD. \u0000Methods \u0000This work is a cross-sectional study that uses data from research realized in Federal University of Pernambuco (UFPE), approved by the Ethics and Research Committee and labeled under the number 81287.9.0000.5208... \u0000(To see the complet abstract, please, check out the PDF.)","PeriodicalId":12925,"journal":{"name":"Headache Medicine","volume":"47 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91484729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Brain volumetry by voxel-based-morphometry in migraineurs: comparison between groups and clinical correlations","authors":"Natália de Oliveira Silva, Nicoly Machado Maciel, G. Carvalho, D. Bevilaqua-Grossi, A. C. D. Santos, F. Dach","doi":"10.48208/headachemed.2022.supplement.45","DOIUrl":"https://doi.org/10.48208/headachemed.2022.supplement.45","url":null,"abstract":"Background \u0000Migraine was previously interpreted as “benign” disease since the major part of patients were asymptomatic between attacks and brain lesions are absent in primary headaches. Advances in structural neuroimaging have changed this point of view. Voxel-based-morphometry is an accurate technique to evaluate objectively structural brain damage. Our hypothesis was that some clinical features of migraine, as aura and attack frequencies, are more related to volumetric changes in migraineurs brains.  \u0000  \u0000Objectives \u0000To compare brain lobes volumetry between migraine patients (episodic migraine, with and without aura, chronic migraine) and healthy controls. To evaluate the correlations of brain volumetric variables with clinical variables. \u0000  \u0000Methods \u0000This is a cross-sectional study performed with 60 female volunteers, aged between 18 and 55 years old, equally allocated into four groups: episodic migraine without aura, episodic migraine with aura, chronic migraine and controls. The sample was clinically characterized by the following variables: age, number of days with headache in the last month, number of days with aura in the last month, average pain intensity in the last month, disease duration calculated in number of years from the migraine diagnosis to the MRI performance, and the use of prophylactic drugs for migraine. Volunteers underwent brain MRI, and Free Surfer software was used to perform volumetric studies. Statistical analyses included Mann-Whitney test, Kruskal-Wallis test, Dunn test and Spearmann correlations. \u0000  \u0000Results \u0000No statistically relevant differences were found in cerebral lobe volumes and supratentorial white matter in the comparison between groups. Regarding to clinical correlations, age influenced the brain lobes volumetric reduction, as expected, except for the parietal lobe, for which the correlation was not important. The disease duration was correlated with the reduction of the frontal (p<0.001 / r=-0.531), temporal (p=0.003/r=-0.433), parietal (p=0.004/r=-0.431) lobes; when adjusted by age... \u0000  \u0000(To see the complet abstract, please, check out the PDF.)","PeriodicalId":12925,"journal":{"name":"Headache Medicine","volume":"55 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86996496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Painful unilateral facial swelling due to superficial temporal artery thrombosis: a rare presentation of Antiphospholipid Syndrome","authors":"Helena da Cunha Lopes de Lima, Ana Clara Dias Pereira, Naiara Cunha de Moura, V. L. Silva, Hilton Mariano da Silva Júnior","doi":"10.48208/headachemed.2022.supplement.34","DOIUrl":"https://doi.org/10.48208/headachemed.2022.supplement.34","url":null,"abstract":"Introduction\u0000Persistent painful unilateral temporal swelling is rarely seen in clinical practice. Antiphospholipid syndrome (APS) is an autoimmune and systemic disorder that causes changes in blood clotting homeostasis, marked by arterial or venous thrombosis, gestational morbidity, and high and persistently positive serum levels of antiphospholipid antibodies (aPL). APS is more common in young women and middle-aged adults, with no preference for race. Among its clinical features, temporal artery thrombosis, associated with headache and temporal and hemifacial edema is extremely rare, with few publications worldwide on this topic.\u0000Objective\u0000This report aims to present the case of a unilateral painful facial edema due to thrombosis of the superficial temporal artery as an unprecedented manifestation of Antiphospholipid Syndrome. Thus, the only record in the English-language literature surveyed in the Pubmed database in July 2022 highlights the rarity of this APS presentation and the consequent challenge in suspecting the correct diagnosis for adequate treatment.\u0000Methods \u0000Case report. Data disclosure was authorized by the patient through an informed consent form.\u0000Results\u0000A 32-year-old woman was presented with pain in the right temporal region of her face. The pain was intense, daily and continuous, pulsating, without irradiation, which worsened with physical activity and presented partial relief with common analgesics. After 20 days, she developed a right pale temporal edema (Figure 1) associated with a significant worsening of pain and intense right unilateral headache attacks triggered by chewing and speaking. She has a history of deep vein thrombosis in the left lower limb. Physical examination and imaging tests showed significant cold edema of the right temporal region with asymmetry of the temporal muscles, which was extremely painful on palpation and made it difficult to open the mouth. There were no other changes in the general physical... \u0000(Too see the complete abstract, please, check out the PDF.)","PeriodicalId":12925,"journal":{"name":"Headache Medicine","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86364272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"\"Not otherwise specified headache\" in emergency department: an analysis of 149,603 visits to nine Upa's 24h in Fortaleza","authors":"J. Carvalho, Jamille Alves, Fernanda Severino, V. Reis, Flavio Deulefeu","doi":"10.48208/headachemed.2022.supplement.46","DOIUrl":"https://doi.org/10.48208/headachemed.2022.supplement.46","url":null,"abstract":"Introduction \u0000Headache is one of the most common neurological symptoms and is almost a universal experience that requires medical attention on many occasions. Patients often seek medical advice for headaches in primary or secondary health care systems. In these scenarios, establishing the correct diagnosis of headache and referring further treatment to a specialist is essential. Hundreds of low-complexity Emergency Care Units (called UPAs 24h) were opened throughout the country in the last decade. Working 24/7, many UPA 24 h are one of the preferred places by patients to treat acute headaches. \u0000Objectives \u0000This study aims to evaluate the frequency of the \"Not otherwise specified headache diagnoses\" in patients who seek UPA's 24-h for headache. \u0000Methods \u0000We evaluated the ED charts of 149,603 visits motivated by headache to nine UPAs 24h in Fortaleza, Ceará, from January 2017 to April 2022. In addition to the demographic data, the care flow chart, the MTS classification, the times of each step of care (from risk classification to discharge or death), and the final diagnosis coded by the attendant physician using the International Classification of Diseases (ICD-10). Data were analyzed using statistical software, and a p <0.05 was considered for significance. \u0000Results \u0000The 149,603 consultations, which represented 3,5% of the total, were made by men and women (72 and 28% respectively) with 38.2 (± 14.6) years of age, on average. Regarding the diagnosis, only 25,121 (16.8%) patients received the diagnosis of migraine, and 4,671 (3.1%) were diagnosed with “other cephalic algic syndromes”. The remaining 119,811 (80.1%) had the not otherwise specified headache discharge diagnosis in their charts. \u0000(To see the complet abstract, please, check out the PDF.)","PeriodicalId":12925,"journal":{"name":"Headache Medicine","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87522252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spontaneous pneumorrachia: a rare cause of thunderclap headache","authors":"R. Domingues, Saulo Ribeiro, Ana Lúcia Parizi Mello, J. Brainer, C. Miranda, D. Bezerra, Gustavo Kuster","doi":"10.48208/headachemed.2022.supplement.37","DOIUrl":"https://doi.org/10.48208/headachemed.2022.supplement.37","url":null,"abstract":"Objective\u0000To present a rare cause of thunderclap headache\u0000Case presentation\u0000Female patient, 39 years old, was admitted to the emergency department of a private hospital in the city of São Paulo, after a sudden and explosive headache followed by two episodes of syncope and motor deficit in the left upper limb. Neurological examination showed weakness of the left upper limb without sensitive impairment. She had previous history of bipolar affective disorder, chronic anemia, and overweight with previous bariatric surgery.\u0000The patient was submitted to computed tomography (CT), arterial angiotomography of the skull and cervical neck, which showed rare small gaseous foci in the perivertebral soft tissues and extradural site on the left side in the craniovertebral transition, near the foramen magnum. Small foci of pneumocephalus were found in the posterior fossa, near the left sphenopetrous fissure. Electroneuromyography (ENMG) of four limbs and brain and cervical magnetic resonance imaging (MRI) were performed 48 hours after initial CT scan. ENMG was normal and MRI showed no more expression of the changes described on CT. She was treated with analgesia and was discharged with full reversion of initial symptoms.\u0000Conclusion\u0000Spontaneous pneumorrhachia is rare disease and is characterized by the presence of air in the spinal canal, both in the intradural and extradural compartments. It is usually benign with spontaneous resolution. Our patient was included in a stroke investigation protocol, due to the thunderclap headache and focal motor deficit. CT revealed the diagnosis. The cervical CT that was performed in the context of cervical CT angiography of the stroke protocol allowed the correct diagnosis. \u0000Key-words: Thunderclap headache, Spontaneous Pneumorrhachia, Cervical Computed Tomography Angiography.","PeriodicalId":12925,"journal":{"name":"Headache Medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90102916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Headache in patients with systemic lupus erythematosus: a pilot study","authors":"Igor de Oliveira, B. Fontes, H. Mariz, A. Duarte, P. Rocha-Filho","doi":"10.48208/headachemed.2022.supplement.28","DOIUrl":"https://doi.org/10.48208/headachemed.2022.supplement.28","url":null,"abstract":"Introduction\u0000Headache is a symptom frequently reported by patients with Systemic Lupus Erythematosus (SLE), but it remains controversial as to whether the prevalence is higher than in the those without the disease and if there is an association with disease activity.\u0000Objectives\u00001) to compare the prevalence, monthly frequency and impact of headaches between patients with SLE and a control group without the disease and 2) to compare the prevalence, monthly frequency and impact of headaches between patients with active SLE and those without disease activity\u0000Methods\u0000This is a case-control study. The case group consisted of patients diagnosed with SLE in regular follow-up at the Rheumatology outpatient clinic of the Hospital das Clínicas, UFPE, excluding those with a previous diagnosis of secondary headache or overlapping autoimmune diseases. A control group, matched for sex and age, consisted of hospital staff and friends and relatives of patients who had no previous diagnosis of secondary headache or autoimmune disease. Data on SLE and headache were collected through interviews and questionnaires administered by a neurologist. Headache impact was assessed using the Headache Impact Test (HIT-6) scale, anxiety and depression symptoms were assessed using the Hospital Anxiety and Depression Scale (HADS) and disease activity was evaluated using the Systemic Lupus Erythematosus Disease Activity Index (SLEDAI)-2K modified scale, considering clinical and laboratory data from the last 30 days. All participants who reported at least one headache attack in the last year were considered as having headache and specific diagnoses were made based on the 3rd edition of the International Classification of Headache Disorders. SLE patients with SLEDAI-2K ≥ 6 were considered as having disease activity. Statistical analyzes were performed in SPSS 28.0 with significance defined as p < 0.05....\u0000(To see the complet abstract, please, check out the PDF.)","PeriodicalId":12925,"journal":{"name":"Headache Medicine","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78018421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neurological sequelae in a patient with previous neurocysticercosis","authors":"Maria Eduarda Oliveira Onuki, B. Martuscelli, Daiene Caroline Lapo Gomes, Flávia Rodrigues de Oliveira, Giovana Meira Muller, S. Ferreira, E. Santos","doi":"10.48208/headachemed.2022.supplement.38","DOIUrl":"https://doi.org/10.48208/headachemed.2022.supplement.38","url":null,"abstract":"Introduction\u0000Teniasis and cysticercosis are caused by the platelminth Taenia solium, a parasite that has in its cycle the pig and man. Teniasis occurs with the ingestion of raw or undercooked contaminated pork containing cysticercus. On the other hand, human cysticercosis occurs through ingestion of T. solium eggs through fresh vegetables, raw meat or contaminated water, in the body, the larvae migrate and acquire the cystic form, usually in the host's muscle tissue.Neurocysticercosis (NCC) develops when the invasion of the larvae occurs in the human central nervous system, found in the nervous tissue or in the intraventricular, subarachnoid, and spinal cord spaces, where there is circulation of CSF, leading to different clinical manifestations and prognosis.\u0000Objective\u0000To report the case of a patient with NCC with neurological complications at IIER.\u0000Case description\u0000Female, 37 years old, carrier of Diabetes Mellitus type 2 (DM2), migraine and structural epilepsy. She has a previous history of rheumatic fever in childhood and NCC since 2001, contracted when she lived in the interior of Bahia where she raised pigs and ate this meat, treated at IIER in May/2019. A headache associated with absence and vertigo crises began in October/2020 as consequences of NCC, reasons for which the patient was hospitalized and later referred to the neurology outpatient clinic, after CSF analysis without evident alterations.The patient was admitted to the IIER with a history of intermittent vertigo for 2 days and shooting headache in the right frontal region of the skull, in addition to the return of absence seizures until then extinct since the last hospitalization in October/2020, accompanied by the neurologist physician who increased valproic acid from 1.25g to 1.5g a day, also reported that this time, presents very significant worsening of vertigo.\u0000(To see the complet abstract, please, check out the PDF.)","PeriodicalId":12925,"journal":{"name":"Headache Medicine","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81817263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}