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A62. CYSTIC FIBROSIS AND NON-CF BRONCHIECTASIS: MECHANISTIC INSIGHTS最新文献

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Comparison of Neutrophil Elastase to the Lower Airway Microbiota in Children with Cystic Fibrosis 中性粒细胞弹性蛋白酶与囊性纤维化儿童下气道微生物群的比较
A62. CYSTIC FIBROSIS AND NON-CF BRONCHIECTASIS: MECHANISTIC INSIGHTS Pub Date : 2022-05-01 DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1992
J. O'Connor, B. Wagner, J. Harris, T. Laguna
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引用次数: 0
Th2 Dysfunction in Cystic Fibrosis 囊性纤维化中Th2功能障碍
A62. CYSTIC FIBROSIS AND NON-CF BRONCHIECTASIS: MECHANISTIC INSIGHTS Pub Date : 2022-05-01 DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1993
D. Cook, C. Thomas, A. Wu, A. Norlander, D. Stoltz, R. Peebles
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引用次数: 0
Optimization of DNAI1 mRNA Constructs to Treat Primary Ciliary Dyskinesia DNAI1 mRNA结构优化治疗原发性纤毛运动障碍
A62. CYSTIC FIBROSIS AND NON-CF BRONCHIECTASIS: MECHANISTIC INSIGHTS Pub Date : 2022-05-01 DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2005
M. Hennig, D. Ishimaru, D. Liston, R. Bhattacharjee, M. Sidhu, J. Poniatowski, J.E. Casillas, H. Lister, S. Comini, V. Kharitonov, D. J. Lockhart, B. Wustman
{"title":"Optimization of DNAI1 mRNA Constructs to Treat Primary Ciliary Dyskinesia","authors":"M. Hennig, D. Ishimaru, D. Liston, R. Bhattacharjee, M. Sidhu, J. Poniatowski, J.E. Casillas, H. Lister, S. Comini, V. Kharitonov, D. J. Lockhart, B. Wustman","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2005","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2005","url":null,"abstract":"","PeriodicalId":129198,"journal":{"name":"A62. CYSTIC FIBROSIS AND NON-CF BRONCHIECTASIS: MECHANISTIC INSIGHTS","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127022287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Proteomic Markers of Eosinophilic Inflammation and Disease Severity in Bronchiectasis 支气管扩张中嗜酸性粒细胞炎症和疾病严重程度的蛋白质组学标志物
A62. CYSTIC FIBROSIS AND NON-CF BRONCHIECTASIS: MECHANISTIC INSIGHTS Pub Date : 2022-05-01 DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2004
J. Pollock, H. Keir, A. Shoemark, A. Dicker, Y. Giam, M. Crichton, E. Cant, J.T.J. Huang, J. Chalmers
{"title":"Proteomic Markers of Eosinophilic Inflammation and Disease Severity in Bronchiectasis","authors":"J. Pollock, H. Keir, A. Shoemark, A. Dicker, Y. Giam, M. Crichton, E. Cant, J.T.J. Huang, J. Chalmers","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2004","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2004","url":null,"abstract":"","PeriodicalId":129198,"journal":{"name":"A62. CYSTIC FIBROSIS AND NON-CF BRONCHIECTASIS: MECHANISTIC INSIGHTS","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121554518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Antibody Response to SARS-CoV-2 mRNA Vaccination in Patients with Cystic Fibrosis 囊性纤维化患者对SARS-CoV-2 mRNA疫苗的抗体应答
A62. CYSTIC FIBROSIS AND NON-CF BRONCHIECTASIS: MECHANISTIC INSIGHTS Pub Date : 2022-05-01 DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1996
L. Lee, C.E. Milla, P. S. Kim
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引用次数: 0
The Mucoid Pathobiome and Its Clinical Implications in Non-Cystic Fibrosis Bronchiectasis 非囊性纤维化支气管扩张的黏液病理组及其临床意义
A62. CYSTIC FIBROSIS AND NON-CF BRONCHIECTASIS: MECHANISTIC INSIGHTS Pub Date : 2022-05-01 DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2001
L. Fernández-Barat, R. López-Aladid, V. Alcaraz, N. Vázquez, L. Bueno, R. Pastor, L. Lingren, H. Sanz, P. Oscanoa, R. Amaro, A. Motos, R. Cabrera, J. Vila, D. Martínez, J. Otero, R. Farré, N. Høiby, A. Torres
{"title":"The Mucoid Pathobiome and Its Clinical Implications in Non-Cystic Fibrosis Bronchiectasis","authors":"L. Fernández-Barat, R. López-Aladid, V. Alcaraz, N. Vázquez, L. Bueno, R. Pastor, L. Lingren, H. Sanz, P. Oscanoa, R. Amaro, A. Motos, R. Cabrera, J. Vila, D. Martínez, J. Otero, R. Farré, N. Høiby, A. Torres","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2001","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2001","url":null,"abstract":"","PeriodicalId":129198,"journal":{"name":"A62. CYSTIC FIBROSIS AND NON-CF BRONCHIECTASIS: MECHANISTIC INSIGHTS","volume":"93 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129762967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Relationship Between Airway Interleukin-1 Beta, Microbial Dysbiosis and Mucus Hyperconcentration in Bronchiectasis: The EMBARC-BRIDGE Study 支气管扩张患者气道白细胞介素-1 β、微生物生态失调和粘液浓度升高的关系:EMBARC-BRIDGE研究
A62. CYSTIC FIBROSIS AND NON-CF BRONCHIECTASIS: MECHANISTIC INSIGHTS Pub Date : 2022-05-01 DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1997
L. Perea, H. Richardson, A. Dicker, E. Cant, M. Bottier, M. Shuttleworth, H. Keir, Y. Giam, S. Finch, J.T.J. Huang, M. Shteinberg, P. Goeminne, E. Polverino, J. Altenburg, F. Blasi, T. Welte, S. Aliberti, O. Sibila, J. Chalmers, A. Shoemark
{"title":"The Relationship Between Airway Interleukin-1 Beta, Microbial Dysbiosis and Mucus Hyperconcentration in Bronchiectasis: The EMBARC-BRIDGE Study","authors":"L. Perea, H. Richardson, A. Dicker, E. Cant, M. Bottier, M. Shuttleworth, H. Keir, Y. Giam, S. Finch, J.T.J. Huang, M. Shteinberg, P. Goeminne, E. Polverino, J. Altenburg, F. Blasi, T. Welte, S. Aliberti, O. Sibila, J. Chalmers, A. Shoemark","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1997","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1997","url":null,"abstract":"","PeriodicalId":129198,"journal":{"name":"A62. CYSTIC FIBROSIS AND NON-CF BRONCHIECTASIS: MECHANISTIC INSIGHTS","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124421337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Airway Obstruction Produces Chronic Hypoxia-Dependent Cellular Adaptation and Mucus Dehydration in Human Airway Epithelial Cells 气道阻塞在人气道上皮细胞中产生慢性缺氧依赖性细胞适应和粘液脱水
A62. CYSTIC FIBROSIS AND NON-CF BRONCHIECTASIS: MECHANISTIC INSIGHTS Pub Date : 2022-05-01 DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1999
Y. Mikami, B. Grubb, T. Rogers, H. Dang, P. Kota, T. Asakura, J. Vilar, R. Gilmore, K. Okuda, L. Morton, G. Chen, L. Sun, M. Gentzsch, S. Randell, W. O'Neal, R. C. Boucher
{"title":"Airway Obstruction Produces Chronic Hypoxia-Dependent Cellular Adaptation and Mucus Dehydration in Human Airway Epithelial Cells","authors":"Y. Mikami, B. Grubb, T. Rogers, H. Dang, P. Kota, T. Asakura, J. Vilar, R. Gilmore, K. Okuda, L. Morton, G. Chen, L. Sun, M. Gentzsch, S. Randell, W. O'Neal, R. C. Boucher","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1999","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1999","url":null,"abstract":"","PeriodicalId":129198,"journal":{"name":"A62. CYSTIC FIBROSIS AND NON-CF BRONCHIECTASIS: MECHANISTIC INSIGHTS","volume":"517 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133431683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Novel Mucolytic Agent MUC-031 Reduces Airway Mucus Plugging and Inflammation in Mice with Muco-Obstructive Lung Disease 新型黏液溶解剂muco -031减轻黏液阻塞性肺疾病小鼠气道黏液堵塞和炎症
A62. CYSTIC FIBROSIS AND NON-CF BRONCHIECTASIS: MECHANISTIC INSIGHTS Pub Date : 2022-05-01 DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1987
A. Addante, R. Wilfred, A. Kuppe, J. Duerr, M. Daniltchenko, M. Drescher, S. Oscarson, A. Healy, I. Gitlin, J. Fahy, M. Mall
{"title":"The Novel Mucolytic Agent MUC-031 Reduces Airway Mucus Plugging and Inflammation in Mice with Muco-Obstructive Lung Disease","authors":"A. Addante, R. Wilfred, A. Kuppe, J. Duerr, M. Daniltchenko, M. Drescher, S. Oscarson, A. Healy, I. Gitlin, J. Fahy, M. Mall","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1987","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1987","url":null,"abstract":"","PeriodicalId":129198,"journal":{"name":"A62. CYSTIC FIBROSIS AND NON-CF BRONCHIECTASIS: MECHANISTIC INSIGHTS","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125578423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rescue of Ciliary Function in Cell-Based Primary Ciliary Dyskinesia Models Using Nebulized, Lipid Nanoparticle (LNP)-Formulated mRNA 使用雾化脂质纳米颗粒(LNP)配制mRNA挽救基于细胞的原发性纤毛运动障碍模型的纤毛功能
A62. CYSTIC FIBROSIS AND NON-CF BRONCHIECTASIS: MECHANISTIC INSIGHTS Pub Date : 2022-05-01 DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1998
R. Bhattacharjee, M. Hennig, D. Ishimaru, D. R. Liston, J. Eby, C. C. Corona, J.E. Casillas, T. Molla, M. Sidhu, J. Poniatowski, S. Comini, A. Ashworth, X. Yu, P. Gao, H. Lister, O.M. Mousa, H. Golliher, W. Yin, P. Sears, M.J. Torres, D. Siegwart, V. Kharitonov, L. Ostrowski, D. J. Lockhart, B. Wustman
{"title":"Rescue of Ciliary Function in Cell-Based Primary Ciliary Dyskinesia Models Using Nebulized, Lipid Nanoparticle (LNP)-Formulated mRNA","authors":"R. Bhattacharjee, M. Hennig, D. Ishimaru, D. R. Liston, J. Eby, C. C. Corona, J.E. Casillas, T. Molla, M. Sidhu, J. Poniatowski, S. Comini, A. Ashworth, X. Yu, P. Gao, H. Lister, O.M. Mousa, H. Golliher, W. Yin, P. Sears, M.J. Torres, D. Siegwart, V. Kharitonov, L. Ostrowski, D. J. Lockhart, B. Wustman","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1998","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1998","url":null,"abstract":"","PeriodicalId":129198,"journal":{"name":"A62. CYSTIC FIBROSIS AND NON-CF BRONCHIECTASIS: MECHANISTIC INSIGHTS","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121023427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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