IF 4.4 2区医学

Heart Pub Date : 2026-10-09 DOI: 10.1136/heartjnl-2025-326668

Chaojun Yang, Zhixing Fan, Jing Zhang, Hui Wu, Zeng Ping, Huibo Wang, Ying Yang, Qi Li, Jian Yang

引用次数: 0

Invisible threats, visible consequences: metabolomic footprints of air pollution on heart failure. 无形的威胁，可见的后果：空气污染对心力衰竭的代谢足迹。

IF 4.4 2区医学

Heart Pub Date : 2026-10-09 DOI: 10.1136/heartjnl-2026-327798

Ryosuke Sato, Constanze Schmidt, Stephan von Haehling

引用次数: 0

Importance of observational studies in the evidence-based medicine framework: the case of bleeding risk in patients with acute myocardial infarction and cancer. 观察性研究在循证医学框架中的重要性：急性心肌梗死和癌症患者出血风险的案例。

IF 4.4 2区医学

Heart Pub Date : 2026-10-09 DOI: 10.1136/heartjnl-2025-327666

Pietro Ameri, Mamas A Mamas, Massimiliano Camilli

引用次数: 0

Timing of heart failure diagnosis and uptake of newly recommended therapies following clinical guideline updates. 心衰诊断的时机和临床指南更新后新推荐疗法的接受。

IF 4.4 2区医学

Heart Pub Date : 2026-10-08 DOI: 10.1136/heartjnl-2025-327578

Maria Klitgaard Christensen, Andreas Kristian Pedersen, Vibe Bolvig Hyldgård, Jacob Eifer Moller

引用次数: 0

Baseline invasive haemodynamics and treatment response to transcatheter tricuspid edge-to-edge repair: an exploratory analysis of the TRI-FR randomised trial. 经导管三尖瓣边缘到边缘修复的基线侵入性血流动力学和治疗反应：TRI-FR随机试验的探索性分析。

IF 4.4 2区医学

Heart Pub Date : 2026-10-08 DOI: 10.1136/heartjnl-2026-328062

Erwan Donal, Guillaume Leurent, Andromahi Zygouri, Karl P Rommel, Prayuth Rasmeehirun, Romain Pierrard, Nicole Karam, Pierre-Yves Leroux, Julien Dreyfus, Augustin Coisne, Guerin Patrice, Frédéric Rouleau, Jean-Noel Trochu, Vincent Auffret, Guillaume L'official, Emmanuel Oger

引用次数: 0

Time is more than myocardium: direct transfer after cardiac arrest with ST-segment elevation. 心脏骤停伴st段抬高后心肌直接转移时间大于。

IF 4.4 2区医学

Heart Pub Date : 2026-10-07 DOI: 10.1136/heartjnl-2026-329093

Tharusan Thevathasan, Steffen Desch

引用次数: 0

Carbon footprint of cardiovascular technologies: a new dimension of value. 心血管技术的碳足迹：价值的新维度。

IF 4.4 2区医学

Heart Pub Date : 2026-10-07 DOI: 10.1136/heartjnl-2026-328828

Ana Paula Beck Da Silva Etges, Carisi Anne Polanczyk

引用次数: 0

Long-term cortisol exposure and echocardiographic measures of cardiac structure and function. 长期皮质醇暴露和心脏结构和功能的超声心动图测量。

IF 4.4 2区医学

Heart Pub Date : 2026-10-07 DOI: 10.1136/heartjnl-2026-328566

Simon Söderholm, Åshild Olsen Faresjö, David Kylhammar, Carl Johan Östgren, Claudio Cantù, Fredrik Iredahl

{"title":"Long-term cortisol exposure and echocardiographic measures of cardiac structure and function.","authors":"Simon Söderholm, Åshild Olsen Faresjö, David Kylhammar, Carl Johan Östgren, Claudio Cantù, Fredrik Iredahl","doi":"10.1136/heartjnl-2026-328566","DOIUrl":"https://doi.org/10.1136/heartjnl-2026-328566","url":null,"abstract":"Background: Chronic activation of the hypothalamic-pituitary-adrenal axis due to long-term stress, reflected by elevated hair cortisol concentration (HCC), has been associated with increased cardiovascular disease risk. However, whether prolonged cortisol exposure is linked to alterations in cardiac structure and function remains unclear.Methods: In a population-based cohort of 3005 individuals aged 50-64 years in Sweden, HCC was measured and analysed in relation to 19 echocardiographic parameters reflecting cardiac morphology and function. Through linear regression models the association between HCC and echocardiographic parameters was analysed, adjusting for relevant confounders and complemented by sensitivity analyses to assess influence of extreme values and to evaluate potential non-linearity.Results: No significant association between HCC and three broad principal component analysis-derived cardiac phenotypes was observed. Across 19 individual echocardiographic measures, effect estimates were generally small and CIs largely included the null. Left Atrial End-Systolic Volume Index (LAESVI) was the only measure showing a false discovery rate-adjusted significant association with HCC; however the magnitude of this association was modest, with β=0.178 SD per one-unit increase in log10-HCC, corresponding to approximately 0.734 mL/m² higher LAESVI across the IQR of HCC (~2.9% of the cohort median).Conclusions: Taken together, in this population-based study, these findings provide little evidence that HCC is associated with clinically meaningful differences in cardiac structure or function in generally healthy middle-aged adults.","PeriodicalId":12835,"journal":{"name":"Heart","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149127289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sudden cardiac death due to aortic stenosis. 主动脉狭窄引起的心源性猝死

IF 4.4 2区医学

Heart Pub Date : 2026-10-07 DOI: 10.1136/heartjnl-2026-328438

Matti Riihiniemi, Elias Törmäkangas, Jarkko Piuhola, Matti Niemelä, Lassi Mäntyniemi, Juha Vähätalo, Anette Eskuri, Ida King, Lasse Pakanen, Juha Perkiömäki, Lauri Holmström, Heikki V Huikuri, Juhani Junttila

{"title":"Sudden cardiac death due to aortic stenosis.","authors":"Matti Riihiniemi, Elias Törmäkangas, Jarkko Piuhola, Matti Niemelä, Lassi Mäntyniemi, Juha Vähätalo, Anette Eskuri, Ida King, Lasse Pakanen, Juha Perkiömäki, Lauri Holmström, Heikki V Huikuri, Juhani Junttila","doi":"10.1136/heartjnl-2026-328438","DOIUrl":"https://doi.org/10.1136/heartjnl-2026-328438","url":null,"abstract":"Background: Characteristics of subjects with sudden cardiac death (SCD) due to aortic stenosis (AS) are not well defined. Aim of this study was to present clinical and autopsy findings of SCD subjects in whom AS was determined to be the cause of death.Methods: Study population was based on the Finnish Genetic Study of Arrhythmic Events (Fingesture), a large registry which included 5869 consecutive subjects of autopsy-verified SCD between 1998 and 2017. The cause of death was determined based on medicolegal investigation combining data from medical records, police reports and autopsy. Clinical history, ECGs and echocardiographic data were reviewed when available.Results: Valvular heart disease (VHD) was determined to be the cause of SCD in 64 subjects (1.1%), where AS was the most frequent cause of SCD due to VHD (68.8%). The average age in victims of SCD due to AS was 67.5±12.1 years and 79.5% were male. Documented angina or dyspnoea prior to SCD due to AS was rare (6.8% and 4.5%, respectively), and over half of the SCD subjects (54.5%) did not have a previously established diagnosis of AS. Almost all subjects (93.2%) with SCD due to AS had cardiac hypertrophy and myocardial fibrosis at autopsy.Conclusions: VHD is a rare cause of SCD, where AS is the dominant underlying pathology. SCD due to AS occurs often without previous diagnosis. Near-universal presence of cardiac hypertrophy and myocardial fibrosis at autopsy supports the role of advanced myocardial disease in the pathogenesis of SCD due to AS.","PeriodicalId":12835,"journal":{"name":"Heart","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149127335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sex and early ventricular fibrillation in fulminant myocarditis: an arrhythmic signal without an observed mortality difference. 性别与暴发性心肌炎的早期心室颤动：无观察到的死亡率差异的心律失常信号。

IF 4.4 2区医学

Heart Pub Date : 2026-10-05 DOI: 10.1136/heartjnl-2026-328949

Dimitri Arangalage, Trecy Gonçalves

引用次数: 0

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