Bioceramics Development and Applications最新文献_第6页

Restoration of Tooth Enamel Using a Flexible Hydroxyapatite Sheet Coated with Tricalcium Phosphate 用柔性羟基磷灰石片包覆磷酸三钙修复牙釉质

Bioceramics Development and Applications Pub Date : 2013-08-23 DOI: 10.4172/2090-5025.S1-006

E. Yamamoto, N. Kato, Arata Isai, H. Nishikawa, M. Kusunoki, K. Yoshikawa, S. Hontsu

引用次数: 8

Bioavailability of Strontium Ions from Bioactive Glasses In Vivo: A Micro-PIXE Study of Trace Elements at the Bone Interface 体内生物活性玻璃中锶离子的生物利用度:骨界面微量元素的微像素研究

Bioceramics Development and Applications Pub Date : 2013-08-23 DOI: 10.4172/2090-5025.S1-004

J. Lao, J. Lacroix, J. Nohra, N. Naaman, J. Sautier, douard Jallot

引用次数: 6

A New Synthetic Diet Increased Bone Mineral Density and Strength of Ovariectomized Rat 一种新型合成饲粮提高去卵巢大鼠骨密度和强度

Bioceramics Development and Applications Pub Date : 2013-08-22 DOI: 10.4172/2090-5025.S1-003

H. Nakada, Takehiro Watanabe, Takahiro Takahashi, K. Fujita, Y. Tanimoto, M. Teranishi, Takao Kato, Y. Kawai, T. Sakae, R. Legeros

引用次数: 1

Characterization of β-TCP, β-TCMP and BCMP Produced by Hydrolysis 水解制备β-TCP、β-TCMP和BCMP的表征

Bioceramics Development and Applications Pub Date : 2013-08-22 DOI: 10.4172/2090-5025.S1-001

Rc Richard, J. Dai, Sader, G. Soares, Rmsm Thir

引用次数: 2

Effect of Stressed and Unstressed Cell Culture Environments on the Viability of MC3T3 Cells with Calcium Phosphates 应激和非应激细胞培养环境对磷酸钙诱导MC3T3细胞活力的影响

Bioceramics Development and Applications Pub Date : 2013-08-22 DOI: 10.4172/2090-5025.S1-002

M. Lopez-Heredia, R. Gildenhaar, G. Berger, Ulf Linow, C. Gomes, J. Gnster, Houshm, M. Stiller, C. Knabe-Ducheyne

{"title":"Effect of Stressed and Unstressed Cell Culture Environments on the Viability of MC3T3 Cells with Calcium Phosphates","authors":"M. Lopez-Heredia, R. Gildenhaar, G. Berger, Ulf Linow, C. Gomes, J. Gnster, Houshm, M. Stiller, C. Knabe-Ducheyne","doi":"10.4172/2090-5025.S1-002","DOIUrl":"https://doi.org/10.4172/2090-5025.S1-002","url":null,"abstract":"The effect of Fetal Bovine Serum (FBS) deprivation on survival and apoptosis of osteoblasts cultured on various calcium phosphates was studied. Test materials were two calcium alkali orthophosphates (materials denominated: GB9 and GB14), which were compared to β-tricalcium phosphate (TCP). Tissue culture polystyrene (PS) served as control. Test materials were characterized by X-Ray Diffraction and scanning electron microscopy. An apoptotic challenge assay entailing serum withdrawal was applied: MC3T3-E1 osteoblasts were cultured for 72h on the test materials in serum containing medium, followed by incubation in serum free medium for another 24h. Serum withdrawal is an apoptotic challenge, which creates a stressed environment. Cells cultured on the test specimens in serum containing medium served as control. The TUNEL Assay was employed to quantify the percentage of apoptotic cells. GB9 and GB14 displayed a significantly lower percentage of apoptotic cells than TCP. TCP had significantly fewer apoptotic cells than PS. The percentage of apoptotic cells on GB9 and GB14 was less than 10%, while the number of apoptotic cells found on the untreated control specimens ranged between 5 and 7%. These findings indicate that GB9 and GB14 endow osteoblasts cultured on them with a decreased sensitivity to apoptosis, which corresponds well with the results of previous in vitro and in vivo studies.","PeriodicalId":127691,"journal":{"name":"Bioceramics Development and Applications","volume":"91 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125531872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quantitative Comparison of Osteoconduction between Porous Apatite and Wollastonite-Containing Glass-Ceramics with 5 Different Pore Sizes 多孔磷灰石与硅灰石5种不同孔径微晶玻璃的骨传导定量比较

Bioceramics Development and Applications Pub Date : 2011-02-03 DOI: 10.4303/BDA/D110152

Takashi Saito, M. Takemoto, S. Fujibayashi, M. Neo, T. Murakami, F. Miyaji, Toshikazu Nakamura

{"title":"Quantitative Comparison of Osteoconduction between Porous Apatite and Wollastonite-Containing Glass-Ceramics with 5 Different Pore Sizes","authors":"Takashi Saito, M. Takemoto, S. Fujibayashi, M. Neo, T. Murakami, F. Miyaji, Toshikazu Nakamura","doi":"10.4303/BDA/D110152","DOIUrl":"https://doi.org/10.4303/BDA/D110152","url":null,"abstract":"Control of the porous morphology and physic- ochemical characteristics of ceramics is important for osteoconduction. In this study, we determined the influence of the porous structure of glass-ceramics that contain apatite and wollastonite (GC-AW) on osteoconduction. For this purpose, we prepared GC-AW cylinders (6 × 15mm) with 5 different pore structures (macropore size, interconnecting pore size, and presence of micropores (pore size, approximately 1µm) for each material were as follows. Material 1000G: 800µm, 150-200µm, ±; material 1000S: 800µm, 175µm, �; material 300G: 250µm, 20µm, and ++; Material 300S: 250µm, 20µm, +; and 200S: 200µm, 50-80µm, �). To evaluate osteoconduction in vivo, these materials were implanted into holes (6mm diameter) made in rabbit femoral condyles. The percentage of bone ingrowth area significantly increased in the case of 300G, 300S, and 200S at 6 and 12 weeks. At 3 weeks after implantation, the rate of bone ingrowth was faster when 1000G, 1000S, and 200S were used than when 300G and 300S were used. These results suggest that GC-AW with a pore size of 800µm is unsuitable for bone growth, and rapid osteoconduction can be achieved at interconnecting pore sizes exceeding 50µm. Further, micropores may not be important for osteoconduction in the case of highly bioactive materials such as GC-AW.","PeriodicalId":127691,"journal":{"name":"Bioceramics Development and Applications","volume":"256 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121239888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Fabrication of Hybrid Composites Consists of Poly Methyl Methacrylate and Polyvinyl Alcohol and Hydroxyapatite 聚甲基丙烯酸甲酯、聚乙烯醇和羟基磷灰石杂化复合材料的制备

Bioceramics Development and Applications Pub Date : 2011-02-03 DOI: 10.4303/BDA/D110171

Viet Van Thai, Young‐Ki Min, Byong-Taek Lee

{"title":"Fabrication of Hybrid Composites Consists of Poly Methyl Methacrylate and Polyvinyl Alcohol and Hydroxyapatite","authors":"Viet Van Thai, Young‐Ki Min, Byong-Taek Lee","doi":"10.4303/BDA/D110171","DOIUrl":"https://doi.org/10.4303/BDA/D110171","url":null,"abstract":"The weakness of bone plate made up from metal alloys and almost ceramics as well as thermosetting polymers is non biodegradable or very slow biodegradable. Thermoplastic and elastomeric polymers are degradable with various rates. A composite consisted of these polymers could be adjusted for required biodegradable rate. Beside, the composites would overcome mechanical behavior requirements to become promising device in tissue engineering. To support this point, fine hydroxyapatite (HAp) particles were penetrated in the composite. A hybrid composite with polymer mixture with HAp was fabricated by electrospinning method. Poly methyl methacrylate (PMMA) is a thermoplastic polymer, it was demon- strated good biocompatibility. However, PMMA inhibited inappropriate degradable rate in prosthetic treatment. Polyvinyl alcohol (PVA) is an elastomeric polymer; it has good biocompatibility, and rapidly bioabsorbable. These polymers were sprayed by electrospinning machine to form mats. HAp, was synthesized by microwave assisted process, and the contents in the composites were 0%, 2%, 4% and 6% by weight. Warm-pressing process was applied to form bone plate from mats. In MTT assay, the composites were non-toxic and showed good biocompatibility.","PeriodicalId":127691,"journal":{"name":"Bioceramics Development and Applications","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130453164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Artificial Bone Substitute of MGSB and Hyaluronate Hydrogels MGSB和透明质酸水凝胶的人工骨替代物

Bioceramics Development and Applications Pub Date : 2011-02-03 DOI: 10.4303/BDA/D110162

J. Yeom, S. Chang, J. K. Park, J. Je, D. Yang, S. Choi, H. Shin, S. Hahn

引用次数: 1

Osteoblast and Fibroblast Culture Proliferation on Injectable Calcium Ceramics Polymer Composite 可注射钙陶瓷聚合物复合材料的成骨细胞和成纤维细胞增殖培养

Bioceramics Development and Applications Pub Date : 2011-02-03 DOI: 10.4303/BDA/D110161

M. Puska, Henna Sihvonen, J. Korventausta, Gissur Oâ¨ rlygsson, P. Vallittu, A. J. Aho

{"title":"Osteoblast and Fibroblast Culture Proliferation on Injectable Calcium Ceramics Polymer Composite","authors":"M. Puska, Henna Sihvonen, J. Korventausta, Gissur Oâ¨ rlygsson, P. Vallittu, A. J. Aho","doi":"10.4303/BDA/D110161","DOIUrl":"https://doi.org/10.4303/BDA/D110161","url":null,"abstract":"Considerable demand for the repair of bone defects cannot be met solely by using biological donor materials. Hence, the use of biocomposites will most likely be increased in reconstructive surgery in future. Metallic implants cannot be used in all cases, because the defects in the skeleton vary greatly, differing from each other in their shape, size, anatomic location, and physiological weight-bearing in the anatomic location. Therefore, more sophisticated orthopaedic materials (e.g. non-metallic fibre-reinforced composites and particulate filler composites) should be available for clinical practice. Our studies have focused on the development of injectable composites of biostable bone cements, i.e. in situ curable resin systems containing impregnated calcium ceramics particles. The properties of the bone cement composites aspire to simulate as closely as possible the mechanical and structural properties of bone. The purpose of this study was to evaluate the in vitro cell proliferation on the experimental injectable biostable polymer modified with calcium ceramics. In the course of proliferation, the cell activity on the calcium ceramics containing biostable polymer composite increased throughout the experiment. As a conclusion, this cell proliferation study indicated that the studied biocomposite has a good potential to promote cell interaction.","PeriodicalId":127691,"journal":{"name":"Bioceramics Development and Applications","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121403184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Study of the bioactivity of various mineral compositions of bioactive glasses 生物活性玻璃中各种矿物成分的生物活性研究

Bioceramics Development and Applications Pub Date : 2011-02-03 DOI: 10.4303/BDA/D110151

H. Oudadesse, M. Mami, R. Doebez-Sridi, P. Pellen, S. Jeanne, A. Zrineh, G. Cathelineau

引用次数: 4