2018 IEEE International Work Conference on Bioinspired Intelligence (IWOBI)最新文献_第5页

Algorithm for History Reconstruction of Viral Recombination Events: Preliminary Results 病毒重组事件历史重建算法:初步结果

2018 IEEE International Work Conference on Bioinspired Intelligence (IWOBI) Pub Date : 2018-07-01 DOI: 10.1109/IWOBI.2018.8464134

Carlos Gomez, G. González, Esteban Meneses

引用次数: 0

Gene Expression Dynamics Induced by Ciprofloxacin and Loss of Lexa Function in Pseudomonas Aeruginosa PAO1 Using Data Mining and Network Analysis 基于数据挖掘和网络分析的环丙沙星诱导铜绿假单胞菌PAO1基因表达动态和Lexa功能丧失

2018 IEEE International Work Conference on Bioinspired Intelligence (IWOBI) Pub Date : 2018-07-01 DOI: 10.1109/IWOBI.2018.8464130

J. Molina-Mora, Rebeca Campos-Sánchez, Fernando Quiles García

{"title":"Gene Expression Dynamics Induced by Ciprofloxacin and Loss of Lexa Function in Pseudomonas Aeruginosa PAO1 Using Data Mining and Network Analysis","authors":"J. Molina-Mora, Rebeca Campos-Sánchez, Fernando Quiles García","doi":"10.1109/IWOBI.2018.8464130","DOIUrl":"https://doi.org/10.1109/IWOBI.2018.8464130","url":null,"abstract":"Pseudomonas aeruginosa is an opportunistic pathogen that causes a variety of infections in humans and frequently develops mechanisms of resistance to antibiotics, which makes its treatment difficult. In this study we applied gene expression analysis using data mining techniques and network analysis to evaluate the temporal effects of exposure to ciprofloxacin and the changes caused by the loss of function of LexA, a regulator of the SOS response to the cellular stress. Initially, global differential expression profiles using clustering algorithms suggested that the effects of antibiotic exposure were determined primarily by time and not by loss of LexA function. This was verified by performing attribute selection and differential expression analysis among conditions, where less than 3.3% of maximum difference between strains but up to 21% of differences were observed over time. Together with network analysis, a significant increase in topological metrics was determined when evaluating temporal changes. Functional annotation showed metabolic pathways enriched over time but not when comparing strains. Overall, the results obtained revealed that the response to ciprofloxacin tends to be exacerbated over time and that it remains stable in the face of the loss of function of LexA activity.","PeriodicalId":127078,"journal":{"name":"2018 IEEE International Work Conference on Bioinspired Intelligence (IWOBI)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127597660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Predicting Cancer Chemosensitivity Based on Intensity/Distribution Profiles of Cells Loaded with a Fluorescent Sphingolipid Analogue 基于装载荧光鞘脂类似物的细胞强度/分布曲线预测癌症化学敏感性

2018 IEEE International Work Conference on Bioinspired Intelligence (IWOBI) Pub Date : 2018-07-01 DOI: 10.1109/IWOBI.2018.8464199

I. Quiros-Fernandez, J. Molina-Mora, M. Kop-Montero, E. Salas-Hidalgo, R. Mora-Rodríguez

{"title":"Predicting Cancer Chemosensitivity Based on Intensity/Distribution Profiles of Cells Loaded with a Fluorescent Sphingolipid Analogue","authors":"I. Quiros-Fernandez, J. Molina-Mora, M. Kop-Montero, E. Salas-Hidalgo, R. Mora-Rodríguez","doi":"10.1109/IWOBI.2018.8464199","DOIUrl":"https://doi.org/10.1109/IWOBI.2018.8464199","url":null,"abstract":"Cancer is a group of heterogeneous and complex diseases, with limited therapeutic options due to the recurrent emergence of drug resistance. Sphingolipids are bioactive molecules that participate in signaling of cell death or proliferation. Because there is no laboratory test to rapidly predict a tumor chemosensitivity, we propose the use of a sphingomyelin fluorescent analogue as a chemotherapy response sensor. Through kinetic live cell imaging experiments, we extracted 1611 fluorescence features with single cell time resolved resolution. After comparing the variations in this reporter, induced by different chemotherapies, it was possible to reduce the system complexity to elaborate a decision tree algorithm based in only 3 fluorescence features capable of predicting chemosensitivity with a 73% of accuracy. This approach serves as a proof of principle for the possible future implementation of a chemosensitivity test that could be used with patient primary tumors, and thus contribute to personalized therapy against cancer.","PeriodicalId":127078,"journal":{"name":"2018 IEEE International Work Conference on Bioinspired Intelligence (IWOBI)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131656491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Selective Face Deidentification with End-to-End Perceptual Loss Learning 基于端到端感知损失学习的选择性人脸去识别

2018 IEEE International Work Conference on Bioinspired Intelligence (IWOBI) Pub Date : 2018-07-01 DOI: 10.1109/IWOBI.2018.8464214

Blaž Meden, P. Peer, V. Štruc

引用次数: 6

Teleoperation of a Humanoid Robot Using an Optical Motion Capture System 基于光学运动捕捉系统的仿人机器人遥操作

2018 IEEE International Work Conference on Bioinspired Intelligence (IWOBI) Pub Date : 2018-07-01 DOI: 10.1109/IWOBI.2018.8464136

M. L.Nunez, D. Dajles, Francisco Siles

引用次数: 7

Design of an Artificial Neural Network Controller for a Tankless Water Heater By Using a Low-Profile Embedded System 基于嵌入式系统的即热式热水器人工神经网络控制器设计

2018 IEEE International Work Conference on Bioinspired Intelligence (IWOBI) Pub Date : 2018-07-01 DOI: 10.1109/iwobi.2018.8464196

Juan Carlos Laurencio-Molina, C. Salazar-García

{"title":"Design of an Artificial Neural Network Controller for a Tankless Water Heater By Using a Low-Profile Embedded System","authors":"Juan Carlos Laurencio-Molina, C. Salazar-García","doi":"10.1109/iwobi.2018.8464196","DOIUrl":"https://doi.org/10.1109/iwobi.2018.8464196","url":null,"abstract":"Tankless water heaters (TWHs) have been become more popular day-by-day in special because of the low-power consumption that characterizes these devices in comparison with the tank water heaters. Nonetheless, it is desirable that these systems have a rapid response to disturbances such as changes in water flow or the inlet temperature. Different methods of classic control have been used for solving this problem for decades. These techniques provide a good solution although not necessarily the optimal one. With the recent boom in automatic control techniques based on Artificial Neural Networks (ANNs) [1]–[3] and the scaling in terms of computational power of embedded systems, this has led to the use of ANNs in low-profile embedded systems. In this work, we present an implementation of an ANN for a commercial application of a TWH running on a low-profile embedded system where we demonstrated that the stabilization time is reduced by up to 25% whilst the overshoot by up to 50%, both in comparison with a classic methods of automatic control using a low-performance microcontroller.","PeriodicalId":127078,"journal":{"name":"2018 IEEE International Work Conference on Bioinspired Intelligence (IWOBI)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123484496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

DNLM-MA-P: A Parallelization of the Deceived Non Local Means Filter with Moving Average and Symmetric Weighting DNLM-MA-P:具有移动平均和对称加权的欺骗非局部均值滤波器的并行化

2018 IEEE International Work Conference on Bioinspired Intelligence (IWOBI) Pub Date : 2018-07-01 DOI: 10.1109/IWOBI.2018.8464180

Saúl Calderón Ramírez, Jorge Castro, Manuel Zurnbado

引用次数: 2

Multi-Objective Operator for Optimal Compression and De-compression of Random Signals 随机信号最优压缩解压缩的多目标算子

2018 IEEE International Work Conference on Bioinspired Intelligence (IWOBI) Pub Date : 2018-07-01 DOI: 10.1109/IWOBI.2018.8464195

Pablo Soto-Quiros, A. Torokhti

引用次数: 0