GeriatricsPub Date : 2026-08-21DOI: 10.3390/geriatrics11040112
Tine Louise Launholt, Palle Larsen, Jemma Hawkins, Hanne Kaae Kristensen
{"title":"Feasibility and Process Evaluation of a Screening Intervention for Early Detection of Malnutrition Risk Among Community-Dwelling Older Adults Receiving Home Care Services.","authors":"Tine Louise Launholt, Palle Larsen, Jemma Hawkins, Hanne Kaae Kristensen","doi":"10.3390/geriatrics11040112","DOIUrl":"10.3390/geriatrics11040112","url":null,"abstract":"<p><strong>Background: </strong>Malnutrition is prevalent among older adults (OAs), ≥65 years, receiving home care services. Despite recommendations for early detection and multifactorial interventions, a gap remains between routine practice and evidence. We therefore developed a complex intervention for early detection of malnutrition risk in a Danish home care setting, comprising an implementation strategy with staff learning activities and a screening procedure with a start-up conversation and follow-up screenings. This article outlines the feasibility test and process evaluation of the intervention.</p><p><strong>Methods: </strong>Guided by the Medical Research Council (MRC/NIHR) framework for complex interventions and MRC process evaluation guidance, the evaluation was conducted in two parts. Part 1 focused on case-level feasibility, while Part 2 examined implementation feasibility within routine home care practice. Qualitative data were collected through participant observations, informal interviews, semi-structured individual interviews, focus group interviews, and a participatory workshop. Quantitative data were extracted from the electronic patient record (NEXUS, Systematic A/S, Aarhus, Denmark). Qualitative data were analysed using qualitative content analysis, and quantitative data using descriptive statistics.</p><p><strong>Results: </strong>All eligible OAs (12/12) received a start-up conversation in Part 1 compared with 5/16 (31%) in Part 2, while follow-up screenings declined from 61/71 (86%) to 37/50 (74%). Overall, staff perceived the learning activities as useful and were able to deliver the screening procedure. However, delivery and implementation were influenced by time constraints, leadership support, workplace culture, and organisational infrastructures. OAs showed willingness to participate, yet their prerequisites for engagement were more limited than anticipated.</p><p><strong>Conclusion: </strong>The intervention could be delivered in a real-world home care setting, but delivery, implementation, and activation of proposed mechanisms were constrained by resource limitations, competing priorities, workplace culture, and organisational infrastructures. To improve uptake, intervention adaptations and a stepwise implementation approach are recommended.</p>","PeriodicalId":12653,"journal":{"name":"Geriatrics","volume":"11 4","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13512152/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148827348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Navigating Adversity in Older Age: An Integrative Review of Contemporary Resilience Concepts and Measurement Challenges.","authors":"Chonlakarn Songsri, Pras Ramluggun, Pimwalunn Aryuwat","doi":"10.3390/geriatrics11040111","DOIUrl":"10.3390/geriatrics11040111","url":null,"abstract":"<p><p><b>Background/Objectives</b>: Ageing populations face complex challenges, yet many older adults maintain well-being despite adversity. Understanding resilience offers critical direction for health promotion. This integrative review takes a conceptual and methodological approach to resilience in older adults, with clear implications for geriatric care. The review addresses: (1) how resilience is conceptualised and measured; (2) individual, social, and contextual factors linked to resilience; and (3) the effectiveness of interventions that aim to promote resilience. <b>Methods</b>: Following Whittemore and Knafl's framework, a systematic search of six databases (PubMed, CINAHL, MEDLINE, Scopus, Web of Science, and Cochrane CENTRAL; 2016-2025) identified 42 empirical studies across 18 countries of diverse designs. Quality was assessed using the Mixed Methods Appraisal Tool, and thematic analysis identified five convergent themes. <b>Results</b>: Most studies explicitly defined resilience using trait-, process-, or outcome-based frameworks and employed validated instruments, most commonly the CD-RISC. Self-efficacy, spirituality, sense of coherence, and gratitude were consistently associated with resilience. Family relationships, social networks, and community participation were important relational correlates. Health status, education, economic security, and digital literacy were key contextual factors. Six longitudinal studies linked higher resilience to reduced mortality, slower cognitive decline, and attenuated frailty progression. Seven intervention studies, including five randomised controlled trials, supported physical activity, mindfulness, positive thinking training, Tai Chi, and technology-supported exercise as promising intervention modalities, though one web-based programme yielded null findings. <b>Conclusions</b>: Resilience in older adults is a multifaceted and potentially modifiable construct. Growing longitudinal evidence extends its relevance beyond psychological well-being to physical health outcomes, though cross-sectional designs predominate and limit causal inference. Measurement heterogeneity across more than twenty instruments underscores the need for international consensus and culturally valid tools. Larger longitudinal studies and adequately powered trials are needed to guide definitive practice and policy for ageing populations worldwide.</p>","PeriodicalId":12653,"journal":{"name":"Geriatrics","volume":"11 4","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13511988/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148827447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
GeriatricsPub Date : 2026-08-19DOI: 10.3390/geriatrics11040110
Mirkka Söderman, Annelie K Gusdal, Lena-Karin Gustafsson
{"title":"Experience of Respite Care with Alternating Housing Among People with Dementia: A Mixed-Methods Study.","authors":"Mirkka Söderman, Annelie K Gusdal, Lena-Karin Gustafsson","doi":"10.3390/geriatrics11040110","DOIUrl":"10.3390/geriatrics11040110","url":null,"abstract":"<p><p><b>Background</b>: In line with international aging policies, most people with dementia receive care at home. Community-based respite services aim to relieve, support, or share caregiving responsibilities. More person-centered knowledge based on experiences from this group is needed to increase informed decisions about planning of qualitative respite care. The aim of this study is to describe how people with dementia experience respite care with alternating housing, i.e., living partly at home, partly in residential care, refer to their everyday life and well-being. <b>Methods</b>: A mixed-methods design was used. The qualitative approach focused on variations of dilemmas in interviews with people with dementia who were granted and received respite care (n = 8). Also, a quantitative approach focused on quality of life using behavioral and psychological symptom scores. <b>Results</b>: Everyday life at the respite care accommodation described by people with dementia included morning routines, variation in the environment, activities in the company of roommates, but also a lack of activities. Social belonging was described by people with dementia through living with roommates and through social contact with the healthcare staff. Quality of life and behavioral and psychological ratings varied between individuals and settings, but no consistent pattern was identified. <b>Conclusions</b>: Respite care appears to maintain a high quality of life and a low level of psychological symptoms for most of the people with dementia. Although the sample was small, these results are nevertheless an important contribution to the phenomenon, experiences of respite care by people with dementia, that need further research. Furthermore, these results can give decision-makers guidance for professional care efforts.</p>","PeriodicalId":12653,"journal":{"name":"Geriatrics","volume":"11 4","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13512120/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148827370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
GeriatricsPub Date : 2026-08-18DOI: 10.3390/geriatrics11040109
Amani Mohammed, Mahmoud Abuhasanein, Martin Wawruch, Viktor Foltin
{"title":"Fragmented Care, Fragmented Safety: Care Coordination and Deprescribing Strategies to Reduce Polypharmacy-Related Harm in Assisted Living-A Public Health Perspective.","authors":"Amani Mohammed, Mahmoud Abuhasanein, Martin Wawruch, Viktor Foltin","doi":"10.3390/geriatrics11040109","DOIUrl":"10.3390/geriatrics11040109","url":null,"abstract":"<p><p><b>Background:</b> Assisted living houses an older, frailer and more heavily medicated population than ever, yet is often regulated as a social and not a clinical setting with no on-site nursing requirement. Polypharmacy accumulates where medication oversight is thinnest. <b>Objective:</b> To map the extent, nature and distribution of research on medication safety in assisted living in the narrow sense, and where the evidence clusters and thins. <b>Methods:</b> In this scoping review, PubMed and Web of Science were searched (26 May 2026; window 2010-2025) and records screened against a strict two-gate rule: assisted living in the narrow sense, explicitly labelled and central, plus a central medication-safety or coordination concept. Residential-care and long-term-care populations fell outside it. Titles, abstracts and full texts were screened and charted thematically. <b>Results:</b> Twenty-two sources met the strict definition, drawn from four countries: the United States (13), Finland (6), Canada (2) and the United Kingdom (1). Five themes emerged, covering burden (4), safety (4), interventions (4), antimicrobial stewardship (4) and coordination and regulation (6). A further 11 comparison-context reports were kept separately. Every randomised trial was Finnish and came from one research programme. <b>Conclusions:</b> Assisted living has become a high-acuity medication environment without matching oversight. The setting-specific literature is real but sparse, and rigorous deprescribing and coordination trials remain scarce. The binding constraint is structural rather than pharmacological, a missing point of clinical accountability that is patterned by regulation, so closing the gap is as much a public-health task as a clinical one.</p>","PeriodicalId":12653,"journal":{"name":"Geriatrics","volume":"11 4","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13511910/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148827422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
GeriatricsPub Date : 2026-08-17DOI: 10.3390/geriatrics11040106
Lourdes Vicent, Rafael Salguero-Bodes, Pablo R Alonso, Helena Alarcos, Elena Puerto García-Martín, Carlos Diaz-Arocutipa, Fernando Arribas Ynsaurriaga, Roberto Martín-Asenjo
{"title":"Beyond Chronological Age: Frailty, Vulnerability, and Invasive Decision-Making in Older Adults with Acute Coronary Syndromes.","authors":"Lourdes Vicent, Rafael Salguero-Bodes, Pablo R Alonso, Helena Alarcos, Elena Puerto García-Martín, Carlos Diaz-Arocutipa, Fernando Arribas Ynsaurriaga, Roberto Martín-Asenjo","doi":"10.3390/geriatrics11040106","DOIUrl":"10.3390/geriatrics11040106","url":null,"abstract":"<p><p>Older adults represent a growing proportion of patients presenting with acute coronary syndromes (ACS), yet they remain a highly heterogeneous population in terms of biological reserve, comorbidity burden, functional status, cognitive performance, and recovery potential. Chronological age alone is an insufficient basis for invasive decision-making, as it may lead to both therapeutic nihilism and disproportionate treatment escalation. Frailty has emerged as a clinically meaningful construct that captures vulnerability to acute stressors and may refine prognostic assessment beyond traditional cardiovascular risk scores. In ACS, frailty is associated with mortality, bleeding, procedural complications, delirium, functional decline, readmission, and loss of independence. However, frailty should not be interpreted as an automatic contraindication to invasive management. Rather, it should inform proportional care by integrating ischemic risk, procedural burden, reversibility potential, patient preferences, and expected quality of recovery. This narrative review examines the role of frailty assessment in older adults with ACS, focusing on its implications for invasive decision-making. We discuss frailty tools, clinical outcomes, therapeutic bias, healthcare inequities, and patient-centered endpoints. Finally, we propose a vulnerability-based framework for cardiovascular care, in which frailty guides individualized therapeutic intensity rather than justifying age-based exclusion from evidence-based treatment.</p>","PeriodicalId":12653,"journal":{"name":"Geriatrics","volume":"11 4","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13512786/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148827351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
GeriatricsPub Date : 2026-08-17DOI: 10.3390/geriatrics11040107
Tejas Ganesh Todmal, Rabia Bibi, Giovanni Cangelosi, Massimiliano Panella, Alice Masini
{"title":"How Gut Microbiota Influence Healthy Aging: Overview of Reviews.","authors":"Tejas Ganesh Todmal, Rabia Bibi, Giovanni Cangelosi, Massimiliano Panella, Alice Masini","doi":"10.3390/geriatrics11040107","DOIUrl":"10.3390/geriatrics11040107","url":null,"abstract":"<p><p><b>Background</b>: Gut microbiota plays a key role in the aging process, with age-related microbial shifts contributing to chronic inflammation, metabolic dysfunction, frailty, and cognitive decline. Despite growing interest, an integrated synthesis of how diet and lifestyle modifications influence gut microbiota remains limited. This overview of reviews summarizes the current evidence on how dietary and lifestyle interventions shape microbial composition and affect aging outcomes. <b>Methods</b>: Following the PRISMA guidelines, we searched PubMed and Scopus for English-language reviews (January 2023-October 2025) including human adults aged ≥ 18 years, evaluating dietary or lifestyle interventions, and reporting gut microbiota with healthy-aging outcomes. Quality of the reviews was appraised using the SANRA tool. <b>Results</b>: Mediterranean and plant-based diets, calorie restriction, and microbiota-targeted approaches such as probiotics, prebiotics, symbiotics, and fecal microbiota transplantation were associated with increases in short-chain fatty acid-producing bacteria, including <i>Faecalibacterium</i>, <i>Bifidobacterium</i>, <i>Lactobacillus</i>, and <i>Akkermansia muciniphila</i>, while reducing pro-inflammatory taxa. These changes were linked to improved metabolic and immune function, reduced inflammaging, lower frailty, and greater physical resilience. Cognitive benefits included decreased neuroinflammation and a lower risk of Alzheimer's and Parkinson's diseases. <b>Conclusions</b>: Maintaining microbial balance through targeted dietary strategies may support healthier, more resilient aging, offering practical insights for public health and clinical nutrition planning.</p>","PeriodicalId":12653,"journal":{"name":"Geriatrics","volume":"11 4","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13512376/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148827426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
GeriatricsPub Date : 2026-08-17DOI: 10.3390/geriatrics11040108
Jordina Muñoz-Padros, Quintí Foguet-Boreu, Emma Puigoriol-Juvanteny, Maite Garolera
{"title":"Premorbid Personality in Alzheimer's Disease and Caregiver Well-Being: The Role of Extraversion.","authors":"Jordina Muñoz-Padros, Quintí Foguet-Boreu, Emma Puigoriol-Juvanteny, Maite Garolera","doi":"10.3390/geriatrics11040108","DOIUrl":"10.3390/geriatrics11040108","url":null,"abstract":"<p><p><b>Objectives:</b> To examine the association between premorbid personality in people with Alzheimer's disease and caregiver well-being, while accounting for caregiver personality, sociodemographic characteristics, and behavioural and psychological symptoms of dementia. <b>Methods:</b> This cross-sectional observational study included 56 dyads consisting of people with mild-to-moderate Alzheimer's disease and their informal caregiver. Caregiver well-being was operationalised using a continuous index derived from a principal component analysis integrating depressive and anxiety symptoms, burden, loneliness, perceived social support, quality of life and happiness. Caregiver personality and the premorbid personality of people with Alzheimer's disease (assessed retrospectively by an informant) were assessed according to the Big Five model. Behavioural and psychological symptoms of dementia were assessed using the Neuropsychiatric Inventory. Associations were examined using correlation analyses and hierarchical multiple linear regression models. <b>Results:</b> Caregivers had a mean age of 55.2 years (SD = 11.0), and 82.1% were women. Higher premorbid extraversion of people with Alzheimer's disease was significantly associated with better caregiver well-being (β = 0.123; <i>p</i> < 0.05), and this association remained significant after adjustment for caregiver personality and other covariates. The final model explained 57.3% of the variance in caregiver well-being (R<sup>2</sup> = 0.573; <i>p</i> < 0.001). <b>Conclusions:</b> Premorbid extraversion of people with Alzheimer's disease was independently associated with caregiver well-being. These findings suggest that personality characteristics of both may be relevant for understanding caregiver well-being within a relational perspective of caregiving.</p>","PeriodicalId":12653,"journal":{"name":"Geriatrics","volume":"11 4","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13512650/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148827540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
GeriatricsPub Date : 2026-08-14DOI: 10.3390/geriatrics11040105
Margaret von Faber, Suzan van der Pas
{"title":"Navigating Support for Informal Caregivers of Older Migrants with Dementia in The Netherlands: Insights from Patient Journey Mapping.","authors":"Margaret von Faber, Suzan van der Pas","doi":"10.3390/geriatrics11040105","DOIUrl":"10.3390/geriatrics11040105","url":null,"abstract":"<p><p><b>Background/Objectives</b>: The aim of the study is to determine factors that affect informal caregivers' ability to care for older migrants with dementia, with a broad aim of providing a framework for improving regional formal support. We used patient journey mapping as a method to identify experiences of informal caregivers. <b>Methods</b>: The study took place in three phases. In the first phase, the content of the patient journey was outlined, and semi-structured interviews were conducted with 14 informal caregivers of people with dementia and a migrant background. In the second phase, results of the interviews were discussed in workshops with professionals. In the third phase, professionals worked together on a plan for improving care and support. <b>Results</b>: Besides positive experiences with care and support, informal caregivers expressed the need for knowledge and training, timely information as well as practical culturally sensitive care and support. Professionals expressed a need for more knowledge of culturally sensitive issues and conversation techniques. They also indicated the need for more integrated care and the ability to offer practical solutions for informal caregivers. As a final result, a multidisciplinary programme on improving knowledge, information for clients, informal caregivers and professionals, use of key figures, culturally sensitive support, a multidisciplinary care path and education for future professionals was launched for the region. <b>Conclusions</b>: A patient journey is a valuable method to pinpoint problems and needs of informal caregivers as well as professionals. It provides a foundation for multidisciplinary communication and collaboration to improve care and support.</p>","PeriodicalId":12653,"journal":{"name":"Geriatrics","volume":"11 4","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13512594/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148827392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
GeriatricsPub Date : 2026-08-11DOI: 10.3390/geriatrics11040104
Danai Sgouropoulou, Maria-Iosifina Kasdagli, Demosthenes B Panagiotakos, Petros P Sfikakis, Evrydiki Kravvariti
{"title":"Long-Term Physical Activity Patterns and Risk of Future Frailty: A Systematic Review and Age-Stratified Meta-Analysis.","authors":"Danai Sgouropoulou, Maria-Iosifina Kasdagli, Demosthenes B Panagiotakos, Petros P Sfikakis, Evrydiki Kravvariti","doi":"10.3390/geriatrics11040104","DOIUrl":"10.3390/geriatrics11040104","url":null,"abstract":"<p><p><b>Background/Objectives</b>: Physical activity (PA) interventions have the potential to delay or reverse frailty in older people, and previous meta-analyses have shown that PA reduces frailty risk. However, introduction and maintenance of PA during midlife might be more impactful as a public health intervention to reduce frailty at the population level. This study aimed to evaluate the impact of longitudinal PA patterns on future frailty risk and to examine whether it is modified by age of onset before vs. after 60 years. <b>Methods</b>: We conducted a systematic review and meta-analysis of prospective population-based cohort studies evaluating the effect of longitudinal PA trajectories on frailty risk of community-dwelling adults below and above 60 years at baseline. Risk ratios (RRs) from studies eligible for quantitative synthesis were pooled using random-effects meta-analysis. Results: Ten studies involving 111,714 participants from Europe, Asia, and North America were included in the systematic review and six in the meta-analysis. Relative to long-term physical inactivity, persistent PA trajectory was associated with 44% reduced risk of frailty (RR = 0.56, 95% CI:0.42-0.76) with moderate certainty, while inclining trajectories were associated with a 38% reduced risk (RR = 0.62, 95% CI: 0.57-0.68) with low certainty. <b>Results</b>: were similar for populations > 60 and <60 years at baseline. <b>Conclusions</b>: Sustained or increasing PA patterns over time are associated with lower risk of future frailty. These findings warrant further implementation studies to quantify the impact of public health policies promoting physically active lifestyles in midlife on the burden of frailty in aging populations.</p>","PeriodicalId":12653,"journal":{"name":"Geriatrics","volume":"11 4","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13512540/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148827418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
GeriatricsPub Date : 2026-08-11DOI: 10.3390/geriatrics11040102
Anahita Gupta, Donna A Culton
{"title":"Autoimmune Oral Mucosal Diseases in Older Patients: An Overview of Early Recognition and Management in the Primary Care Setting.","authors":"Anahita Gupta, Donna A Culton","doi":"10.3390/geriatrics11040102","DOIUrl":"10.3390/geriatrics11040102","url":null,"abstract":"<p><p>Autoimmune oral mucosal diseases, including pemphigus vulgaris, mucous membrane pemphigoid, and oral lichen planus, are important yet frequently underrecognized causes of morbidity in older adults. These conditions often initially present with nonspecific symptoms such as persistent oral pain, erosions, ulcerations, or gingival inflammation, contributing to delays in diagnosis and treatment. Primary care clinicians and geriatricians are uniquely positioned to identify these diseases early and facilitate timely referral for diagnostic confirmation and initiation of therapy. This review provides a practical overview of the clinical presentation, diagnostic evaluation, and initial management of pemphigus vulgaris, mucous membrane pemphigoid, and oral lichen planus and highlights features that should raise suspicion for an autoimmune oral process. In addition to disease-specific therapies, supportive care measures including pain control, oral hygiene counseling, nutritional support, and mental health screening are essential to reducing morbidity and improving quality of life. Special consideration should be given to challenges disproportionately affecting older adults, including frailty, polypharmacy, and social barriers to care. Through timely recognition and a multidisciplinary, patient-centered approach, clinicians can improve outcomes and support the quality of life of this patient population.</p>","PeriodicalId":12653,"journal":{"name":"Geriatrics","volume":"11 4","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13511905/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148827252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}