General Thoracic and Cardiovascular Surgery最新文献

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Comparison of postoperative pain between robotic and uniportal video-assisted thoracic surgery for anatomic lung resection in patients with stage I lung cancer.
IF 1.1 4区 医学
General Thoracic and Cardiovascular Surgery Pub Date : 2025-02-26 DOI: 10.1007/s11748-025-02129-y
Keita Tokuishi, Jun-Ichi Wakahara, Yuichiro Ueda, So Miyahara, Hiroyasu Nakashima, Yoshiko Masuda, Ryuichi Waseda, Takeshi Shiraishi, Toshihiko Sato
{"title":"Comparison of postoperative pain between robotic and uniportal video-assisted thoracic surgery for anatomic lung resection in patients with stage I lung cancer.","authors":"Keita Tokuishi, Jun-Ichi Wakahara, Yuichiro Ueda, So Miyahara, Hiroyasu Nakashima, Yoshiko Masuda, Ryuichi Waseda, Takeshi Shiraishi, Toshihiko Sato","doi":"10.1007/s11748-025-02129-y","DOIUrl":"https://doi.org/10.1007/s11748-025-02129-y","url":null,"abstract":"<p><strong>Objective: </strong>Uniportal video-assisted thoracoscopic surgery (U-VATS) and robot-assisted thoracoscopic surgery (RATS) are widely used, minimally invasive procedures. The present study aimed to compare postoperative pain following U-VATS and RATS anatomical lung resection in patients with clinical stage I lung cancer.</p><p><strong>Methods: </strong>We conducted a retrospective analysis of the data from 133 patients with clinical stage I lung cancer who underwent U-VATS (n = 63), four-arm RATS (n = 70) lobectomy, or segmentectomy between August 2020 and August 2023. Early postoperative outcomes, pain scores through postoperative day 7, and duration of postoperative analgesic use 60 days after surgery were compared using propensity score-matched analysis.</p><p><strong>Results: </strong>In the propensity score-matched analysis, the U-VATS group had a shorter operative time than the RATS group (160 vs. 202 min, respectively; P < 0.001). However, no significant differences were observed in blood loss, chest tube duration, complications, post operative stay length, or number of dissected lymph nodes and stations. The U-VATS group exhibited significantly lower pain scores than the RATS group throughout the entire postoperative period, particularly on postoperative days 1, 2, 3, 4, 5, and 7(P = 0.006, 0.044, 0.032, 0.041, 0.007, and 0.024, respectively). The number of patients who used analgesics for at least 2 months was lower in the U-VATS group than in the RATS group (4 [8.2%] vs. 17 [34.0%], respectively; P = 0.002).</p><p><strong>Conclusion: </strong>U-VATS anatomical lung resection in patients with clinical stage I lung cancer has less postoperative pain than RATS.</p>","PeriodicalId":12585,"journal":{"name":"General Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143515449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trends in serum KL-6 levels following lung transplantation for interstitial lung diseases.
IF 1.1 4区 医学
General Thoracic and Cardiovascular Surgery Pub Date : 2025-02-24 DOI: 10.1007/s11748-025-02117-2
Kazuhisa Matsumoto, Akihiro Ohsumi, Tomohiro Handa, Daisuke Nakajima, Satona Tanaka, Satoshi Hamada, Kohei Ikezoe, Kiminobu Tanizawa, Toyohiro Hirai, Hiroshi Date
{"title":"Trends in serum KL-6 levels following lung transplantation for interstitial lung diseases.","authors":"Kazuhisa Matsumoto, Akihiro Ohsumi, Tomohiro Handa, Daisuke Nakajima, Satona Tanaka, Satoshi Hamada, Kohei Ikezoe, Kiminobu Tanizawa, Toyohiro Hirai, Hiroshi Date","doi":"10.1007/s11748-025-02117-2","DOIUrl":"https://doi.org/10.1007/s11748-025-02117-2","url":null,"abstract":"<p><strong>Objective: </strong>To assess the changes in Krebs von den Lungen-6 (KL-6) levels pre- and post-lung transplantation for interstitial lung disease and to determine the connection between changes in KL-6 levels and chronic lung allograft dysfunction.</p><p><strong>Methods: </strong>Eighty-two lung transplantation procedures were performed in interstitial lung disease patients between January 2008 and December 2019. We compared changes in KL-6 levels before and after transplantation in two groups: unilateral and bilateral lung transplant groups. Additionally, KL-6 levels just before or at the onset of chronic lung allograft dysfunction were compared to the lowest post-transplant levels.</p><p><strong>Results: </strong>In total, 28 female and 49 male patients (median age: 54 years; range 22-64; 42 and 35 patients underwent unilateral and bilateral lung transplantations, respectively) were enrolled. The post-transplant observation period ranged from 8 to 163 (median: 64.2) months. KL-6 levels decreased in 76 patients (98.7%). Notably, the KL-6 level was lower in the bilateral lung transplantation group than in the unilateral lung transplantation group. Moreover, KL-6 levels were higher just before or at the onset of chronic lung allograft dysfunction than the lowest post-transplant levels. These levels were significantly higher than the highest post-transplant levels observed in the non-chronic lung allograft dysfunction group.</p><p><strong>Conclusions: </strong>Our findings suggest that KL-6 levels decrease in interstitial lung disease patients following lung transplantation, with a greater reduction in KL-6 levels observed in bilateral lung transplantation compared to unilateral lung transplantation. Elevated serum KL-6 levels were associated with chronic lung allograft dysfunction, highlighting its utility as a diagnostic biomarker.</p>","PeriodicalId":12585,"journal":{"name":"General Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143482786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Postoperative outcomes of cardiovascular surgery managed by nurse practitioners.
IF 1.1 4区 医学
General Thoracic and Cardiovascular Surgery Pub Date : 2025-02-23 DOI: 10.1007/s11748-025-02132-3
Masato Saitoh, Takuma Yamasaki, Tomoaki Tanabe, Shuichi Tochigi, Daiki Hirayama, Kiyotaka Aoyama, Imun Tei
{"title":"Postoperative outcomes of cardiovascular surgery managed by nurse practitioners.","authors":"Masato Saitoh, Takuma Yamasaki, Tomoaki Tanabe, Shuichi Tochigi, Daiki Hirayama, Kiyotaka Aoyama, Imun Tei","doi":"10.1007/s11748-025-02132-3","DOIUrl":"https://doi.org/10.1007/s11748-025-02132-3","url":null,"abstract":"<p><strong>Objective: </strong>The significant workload of cardiovascular surgeons in Japan has led to a growing interest in implementing nurse practitioners as a means to address this issue. This study seeks to evaluate the postoperative outcomes of cardiovascular surgeries in which nurse practitioners were involved at our institution.</p><p><strong>Methods: </strong>This study utilized a retrospective observational study design. This study included patients who underwent scheduled cardiovascular surgeries at our hospital between April 1, 2019, and March 31, 2024. Patients were divided into two groups for postoperative care management: the DR group (physician only) and the NP group (co-management by physician and nurse practitioner). The primary end point was the 30-day mortality. We compared the two groups.</p><p><strong>Results: </strong>A total of 394 patients were classified into two groups: DR group (n = 101) and NP group (n = 293). There was no significant difference in the 30-day mortality between the two groups. The NP group had significantly shorter hospital stay (NP 20.6 ± 11.1 vs. DR 24.0 ± 11.8; p = 0.01; effect size = 0.299), postoperative length of stay (NP 14.5 ± 8.9 vs. DR 18.0 ± 10.4; p = 0.001; effect size = 0.376), ICU stay (NP 5.2 ± 3.5 vs. DR 6.3 ± 4.5; p = 0.014; effect size = 0.284), and time until 50-m walking (NP 3.8 ± 3.5 vs. DR 5.1 ± 5.1; p = 0.004; effect size = 0.342). There were no significant differences in the incidence of postoperative complications between the two groups.</p><p><strong>Conclusions: </strong>Nurse practitioners have the potential to provide safe care equivalent to that of physicians, and it may contribute to reduced hospital stays and improved postoperative recovery in patients.</p>","PeriodicalId":12585,"journal":{"name":"General Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143482653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Aortic wall degeneration late after ascending aortic wrapping.
IF 1.1 4区 医学
General Thoracic and Cardiovascular Surgery Pub Date : 2025-02-23 DOI: 10.1007/s11748-025-02133-2
Haruna Araki, Tadashi Kitamura, Shinzo Torii, Toshiaki Mishima, Masaomi Fukuzumi, Kagami Miyaji
{"title":"Aortic wall degeneration late after ascending aortic wrapping.","authors":"Haruna Araki, Tadashi Kitamura, Shinzo Torii, Toshiaki Mishima, Masaomi Fukuzumi, Kagami Miyaji","doi":"10.1007/s11748-025-02133-2","DOIUrl":"https://doi.org/10.1007/s11748-025-02133-2","url":null,"abstract":"<p><p>Little is currently known about the pathological changes after aortic wrapping. This study investigated long-term outcomes including pathological findings after ascending aortic wrapping. Of the 30 patients who underwent aortic wrapping from 2004 to 2012, redo surgery was later performed in six patients. All the patients underwent ascending aorta replacement because of safety issues associated with aortic cross clamping due to adhesion. Pathologically, the tunica media had been lost and replaced by foreign body granulation. The wrapped aorta manifested severe erosion late after surgery. The wrapped aorta will likely be replaced in a redo surgery.</p>","PeriodicalId":12585,"journal":{"name":"General Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143482651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Guidelines for preoperative pulmonary function assessment in patients with lung cancer who will undergo surgery (The Japanese Association for Chest Surgery).
IF 1.1 4区 医学
General Thoracic and Cardiovascular Surgery Pub Date : 2025-02-19 DOI: 10.1007/s11748-025-02120-7
Yasuhisa Ohde, Kazuhiro Ueda, Jiro Okami, Hajime Saito, Toshihiko Sato, Eiji Yatsuyanagi, Masanori Tsuchida, Takahiro Mimae, Hiroyuki Adachi, Tomoyuki Hishida, Hisashi Saji, Ichiro Yoshino
{"title":"Guidelines for preoperative pulmonary function assessment in patients with lung cancer who will undergo surgery (The Japanese Association for Chest Surgery).","authors":"Yasuhisa Ohde, Kazuhiro Ueda, Jiro Okami, Hajime Saito, Toshihiko Sato, Eiji Yatsuyanagi, Masanori Tsuchida, Takahiro Mimae, Hiroyuki Adachi, Tomoyuki Hishida, Hisashi Saji, Ichiro Yoshino","doi":"10.1007/s11748-025-02120-7","DOIUrl":"https://doi.org/10.1007/s11748-025-02120-7","url":null,"abstract":"<p><p>This article translates the guidelines for preoperative pulmonary function assessment in patients with lung cancer who will undergo surgery, established by the Japanese Association of Chest Surgery on May 17, 2021, from Japanese to English. The last version of these guidelines was created on April 5, 2011. Over the past decade, changes in clinical practice have occurred that do not align with the current guidelines, prompting a revision in conjunction with the introduction of new evidence this time. This guideline was developed with reference to the internationally adopted GRADE (Grading of Recommendations Assessment, Development, and Evaluation) system. Extraction of evidence, systematic review, and quality assessment are entrusted to each guideline review committee and the Pulmonary Function Assessment Working Group. Committee members are also responsible for determining the selection of evidence and the extraction period, with a particular emphasis on adopting items considered to be of special importance. The recommended assessment and management is categorized into a general overview, pulmonary function assessment, cardiopulmonary exercise test, pulmonary function assessment for lung cancer with interstitial pneumonia, preoperative smoking cessation, and pulmonary rehabilitation. These are described by the strength of recommendation, the strength of evidence, and the consensus rate.</p>","PeriodicalId":12585,"journal":{"name":"General Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143448879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
WTAP-mediated m6A modification on BASP1 mRNA contributes to ferroptosis in AAA.
IF 1.1 4区 医学
General Thoracic and Cardiovascular Surgery Pub Date : 2025-02-19 DOI: 10.1007/s11748-025-02130-5
Zexiang Tian, Wei Li, Jian Wang, Shuzhen Li
{"title":"WTAP-mediated m6A modification on BASP1 mRNA contributes to ferroptosis in AAA.","authors":"Zexiang Tian, Wei Li, Jian Wang, Shuzhen Li","doi":"10.1007/s11748-025-02130-5","DOIUrl":"https://doi.org/10.1007/s11748-025-02130-5","url":null,"abstract":"<p><strong>Background: </strong>Abdominal aortic aneurysm (AAA) is a common aneurysm that is often associated with atherosclerosis and can lead to artery rupture and death. Brain abundant membrane attached signal protein 1 (BASP1) is related to a variety of pathophysiological processes, but its role in AAA has not been reported.</p><p><strong>Methods: </strong>Real-time quantitative polymerase chain reaction (qRT-PCR) and western blot were used to detect the expressions of BASP1 and Wilms' tumor 1-associated protein (WTAP). Angiotensin-II (Ang-II) was employed for inducing AAA models in vitro to explore the effects and mechanism of BASP1 in AAA. Cell viability, apoptosis, oxidative stress level, and Fe<sup>2+</sup> level were measured by the 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl tetrazolium bromide (MTT), flow cytometry, and various kits, respectively. In terms of mechanism, the methylated RNA immunoprecipitation (MeRIP)-qPCR, the dual luciferase reporter assay, and the cytochrome experiments were utilized to evaluate the relationship between BASP1 and WTAP.</p><p><strong>Results: </strong>A highly expressed level of BASP1 was observed in aortic tissues of AAA patients and Ang-II could induce AAA models by treating vascular smooth muscle cells (VSMCs). In cellular function, BASP1 knockdown impaired AAA and ferroptosis resulted from Ang-II. Mechanically, WTAP mediated the N6-methyladenosine (m6A) modification and mRNA stability of BASP1. Meanwhile, WTAP was highly expressed in AAA tissues of patients and the effects of WTAP silence in AAA and ferroptosis were diminished by up-regulated BASP1.</p><p><strong>Conclusion: </strong>WTAP promotes cell viability and inhibits apoptosis and ferroptosis resulted from Ang-II in VSMCs by mediating the m6A level of BASP1.</p>","PeriodicalId":12585,"journal":{"name":"General Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143448881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Guidelines for the treatment of empyema (The Japanese Association for Chest Surgery).
IF 1.1 4区 医学
General Thoracic and Cardiovascular Surgery Pub Date : 2025-02-19 DOI: 10.1007/s11748-025-02119-0
Yuji Shiraishi, Mitsugu Omasa, Shinichi Yamashita, Yoon Hyung-Eun, Masayuki Tanahashi, Takeshi Fukami, Shinichi Tokyooka, Yasuhisa Ode, Tatsuro Okamoto, Takashi Shiraishi, Yasushi Shintani, Yasuhiro Hida, Sumiko Maeda, Isao Matsumoto, Yuichi Sakairi, Mariko Fukui, Katsuhiro Okuda, Masanori Tsuchida, Akira Iyoda, Hisashi Saji, Ichiro Yoshino
{"title":"Guidelines for the treatment of empyema (The Japanese Association for Chest Surgery).","authors":"Yuji Shiraishi, Mitsugu Omasa, Shinichi Yamashita, Yoon Hyung-Eun, Masayuki Tanahashi, Takeshi Fukami, Shinichi Tokyooka, Yasuhisa Ode, Tatsuro Okamoto, Takashi Shiraishi, Yasushi Shintani, Yasuhiro Hida, Sumiko Maeda, Isao Matsumoto, Yuichi Sakairi, Mariko Fukui, Katsuhiro Okuda, Masanori Tsuchida, Akira Iyoda, Hisashi Saji, Ichiro Yoshino","doi":"10.1007/s11748-025-02119-0","DOIUrl":"https://doi.org/10.1007/s11748-025-02119-0","url":null,"abstract":"<p><p>This article translates the guidelines for the treatment of empyema established by the Japanese Association of Chest Surgery in 2023 from Japanese to English. These guidelines were developed by the Working Group on Guidelines for the Treatment of Empyema of our society, involving the establishment of clinical questions, conducting systematic reviews in accordance with the MINDS (Medical Information Distribution Service) Manual for Guideline Development 2020 version 3.0 and the GRADE (Grading of Recommendations Assessment, Development, and Evaluation) system, and determining the levels of recommendations. Furthermore, external evaluators provided assessments. Subsequently, the guidelines were finalized after receiving public comments from the members of the society. Even in the current era of advanced antibiotic therapy, empyema remains difficult to treat. However, the specific guideline for the treatment of empyema lacks in our country. Each institution is conducting clinical practices in its own way. Therefore, aiming to standardize the treatment of empyema, we have developed a practice guideline of empyema treatment. The pathophysiology of empyema is diverse, so empyema is classified into acute, chronic, and postoperative empyema. The recommended surgical treatment for each type of empyema is described, being categorized by the strength of recommendation, strength of evidence, and consensus rate.</p>","PeriodicalId":12585,"journal":{"name":"General Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143448880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lymphatic complication in open venous harvesting versus endoscopic venous harvesting: a systematic review and meta-analysis.
IF 1.1 4区 医学
General Thoracic and Cardiovascular Surgery Pub Date : 2025-02-17 DOI: 10.1007/s11748-025-02126-1
Alireza Razavi, Mehrdad Mahalleh, Amirparsa Vanaki, Amirhossein Fallah, Amirhossein Bahanesteh, Ali Ahmadi, Hossein Yarmohammadi, Morteza Solati Kooshkqazi, Masood Soltanipur
{"title":"Lymphatic complication in open venous harvesting versus endoscopic venous harvesting: a systematic review and meta-analysis.","authors":"Alireza Razavi, Mehrdad Mahalleh, Amirparsa Vanaki, Amirhossein Fallah, Amirhossein Bahanesteh, Ali Ahmadi, Hossein Yarmohammadi, Morteza Solati Kooshkqazi, Masood Soltanipur","doi":"10.1007/s11748-025-02126-1","DOIUrl":"https://doi.org/10.1007/s11748-025-02126-1","url":null,"abstract":"<p><strong>Background: </strong>The methods for saphenous vein (SV) harvesting include bridging vein harvesting (BVH), open vein harvesting (OVH), and endoscopic vein harvesting (EVH). Lymphatic complications, such as lymphatic leak, lymphedema, lymphangitis, and lymphocele, can arise following SV-harvesting surgery. This study aims to compare the incidence of lymphatic complications in SV harvesting using the OVH surgical method versus EVH.</p><p><strong>Methods: </strong>We have systematically searched databases including Scopus, PubMed, and Web of Science until April 2024. Studies were considered eligible for inclusion if they performed SV harvesting and compared lymphatic complications in the EVH with OVH or BVH. Various lymphatic complications and follow-up periods were extracted. A meta-analysis was conducted comparing the relative risk (RR) of lymphatic complications in the EVH group versus the OVH group.</p><p><strong>Results: </strong>Twelve studies were included. A total of 1934 patients were involved and the majority were male. Follow-up times were from 6 days to 34 months. Results of the meta-analysis showed that the pooled lymphatic complications, lymphatic leak, and lymphedema are significantly higher in OVH versus EVH (RR = 6.78, p value < 0.01; RR = 17.33, p value < 0.01; RR = 8.88, p value < 0.01, respectively). No significant differences in lymphocele rates between the two methods (RR = 1.2, p value = 0.77). Both short-term and long-term follow-ups showed elevated lymphatic complication risks in OVH relative to EVH (RR = 4.91, p value < 0.01; RR = 30.27, p value = 0.03, respectively).</p><p><strong>Conclusion: </strong>EVH is linked to reduced rates of lymphatic complications. Also, OVH had a higher risk of lymphatic complications in the short and long term compared to EVH.</p>","PeriodicalId":12585,"journal":{"name":"General Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143440622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk factors for distal stent graft-induced new entry after frozen elephant trunk procedure in chronic aortic dissection.
IF 1.1 4区 医学
General Thoracic and Cardiovascular Surgery Pub Date : 2025-02-06 DOI: 10.1007/s11748-025-02122-5
Sho Akita, Yoshiyuki Tokuda, Yuji Narita, Sachie Terazawa, Tomo Yoshizumi, Hideki Ito, Masato Mutsuga
{"title":"Risk factors for distal stent graft-induced new entry after frozen elephant trunk procedure in chronic aortic dissection.","authors":"Sho Akita, Yoshiyuki Tokuda, Yuji Narita, Sachie Terazawa, Tomo Yoshizumi, Hideki Ito, Masato Mutsuga","doi":"10.1007/s11748-025-02122-5","DOIUrl":"https://doi.org/10.1007/s11748-025-02122-5","url":null,"abstract":"<p><strong>Background: </strong>The frozen elephant trunk (FET) procedure has emerged as an effective single-stage treatment for complex aortic pathologies. However, it carries a risk of distal stent graft-induced new entry (dSINE) in patients with chronic aortic dissection (CAD). This study investigated risk factors associated with dSINE development.</p><p><strong>Methods: </strong>Between 2009 and 2021, 160 FET procedures were performed, including 48 cases of CAD (mean time from onset: 5.6 ± 3.8 years). After excluding five patients due to incomplete 6-month postoperative computed tomography (CT) data, 43 patients were included. A multivariable stepwise Cox proportional hazards regression analysis was conducted to identify predictors of dSINE.</p><p><strong>Results: </strong>During a mean follow-up period of 5.9 ± 3.9 years, dSINE occurred in 22 of 43 patients (51.1%). Univariate analysis identified three significant risk factors for dSINE: total aortic diameter (TAD) > 45 mm at the distal stent-graft level (HR 5.88, 95% CI 1.35-25.52, p = 0.018), True lumen (TL) perimeter-based diameter (HR 1.22, 95% CI 1.03-1.46; p = 0.021), and TL ovality (HR 1.31, 95% CI 1.04-1.65, p = 0.022). Multivariate analysis revealed TAD > 45 mm as an independent risk factor for dSINE (HR 4.60, 95% CI 1.01-20.85, p = 0.048). The 5-year freedom from dSINE was significantly higher in patients with TAD ≤ 45 mm compared to those with TAD > 45 mm (87.5% vs. 20.8%, p < 0.01).</p><p><strong>Conclusions: </strong>Although FET remains an important therapeutic option for CAD, dSINE represents a significant postoperative complication. TAD > 45 mm was identified as an independent risk factor. These findings may guide surgical planning for FET procedures.</p>","PeriodicalId":12585,"journal":{"name":"General Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143255448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Embankment technique in extended sandwich patch repair for post-infarction ventricular septal rupture.
IF 1.1 4区 医学
General Thoracic and Cardiovascular Surgery Pub Date : 2025-02-02 DOI: 10.1007/s11748-025-02125-2
Kosaku Nishigawa, Retsu Tateishi, Shunya Ono, Takeyuki Kanemura
{"title":"Embankment technique in extended sandwich patch repair for post-infarction ventricular septal rupture.","authors":"Kosaku Nishigawa, Retsu Tateishi, Shunya Ono, Takeyuki Kanemura","doi":"10.1007/s11748-025-02125-2","DOIUrl":"https://doi.org/10.1007/s11748-025-02125-2","url":null,"abstract":"<p><p>Extended sandwich patch repair for post-infarction ventricular septal rupture is a surgical technique that closes the defect using two patches, with one on the right ventricular side and the other on the left ventricular side. In this technique, filling materials such as surgical glue are often used between the two patches. We routinely use BioGlue surgical adhesive as a filler. However, there are concerns regarding residual shunts because of incomplete closure of the defect and the risk of embolism caused by the glue leaking into the left ventricle. Therefore, we have developed a technique to create a \"bank\" using an absorbable hemostatic agent between the patch and the defect, aiming to secure defect sealing and prevent embolism caused by the glue. We have named this procedure the \"embankment technique.\" In 11 consecutive cases treated with this procedure, no residual shunts or embolic events were observed.</p>","PeriodicalId":12585,"journal":{"name":"General Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143074510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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