{"title":"Embankment technique in extended sandwich patch repair for post-infarction ventricular septal rupture.","authors":"Kosaku Nishigawa, Retsu Tateishi, Shunya Ono, Takeyuki Kanemura","doi":"10.1007/s11748-025-02125-2","DOIUrl":"10.1007/s11748-025-02125-2","url":null,"abstract":"<p><p>Extended sandwich patch repair for post-infarction ventricular septal rupture is a surgical technique that closes the defect using two patches, with one on the right ventricular side and the other on the left ventricular side. In this technique, filling materials such as surgical glue are often used between the two patches. We routinely use BioGlue surgical adhesive as a filler. However, there are concerns regarding residual shunts because of incomplete closure of the defect and the risk of embolism caused by the glue leaking into the left ventricle. Therefore, we have developed a technique to create a \"bank\" using an absorbable hemostatic agent between the patch and the defect, aiming to secure defect sealing and prevent embolism caused by the glue. We have named this procedure the \"embankment technique.\" In 11 consecutive cases treated with this procedure, no residual shunts or embolic events were observed.</p>","PeriodicalId":12585,"journal":{"name":"General Thoracic and Cardiovascular Surgery","volume":" ","pages":"372-374"},"PeriodicalIF":1.1,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143074510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Early surgical outcomes in the composite-valve root replacement with bioprosthesis after surgery for acute type A aortic dissection.","authors":"Yoshimasa Seike, Kazunori Sakaguchi, Kento Shinzato, Kazufumi Yoshida, Yojiro Koda, Kenta Masada, Yosuke Inoue, Hitoshi Matsuda","doi":"10.1007/s11748-024-02075-1","DOIUrl":"10.1007/s11748-024-02075-1","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to evaluate the surgical outcomes of composite-valve root replacement with bioprosthesis (b-CVRR) after acute type A aortic dissection (AAAD) repair.</p><p><strong>Methods: </strong>We included 41 patients who underwent b-CVRR after surgery for AAAD from 2007 to 2022. We excluded seven patients with VSRR, three with mechanical valve use, one with mycotic aneurysm, and one with cardiopulmonary resuscitation.</p><p><strong>Results: </strong>The overlapping surgical indications for b-CVRR were pseudoaneurysm in 21 patients (51.2%), severe AI in 19 (46.3%), re-dissection in 15 (36.6%), root dilatation (> 50 mm) in 12 (41.5%), and rupture in 3 (7.3%). The coronary artery reconstruction methods were bilateral Carrel patch in 13 patients (32%), Carrel patch with Piehler in 16 patients (38%), bilateral Piehler in six patients (15%), and Piehler with coronary artery bypass (CABG) in six patients (15%). Four patients who underwent the Carrel patch technique required additional intraoperative CABG. Three hospital mortality occurred (7.3%; myonephropathic metabolic syndrome, heart failure, bleeding from the thyroid carotid artery without injury). No thrombosis of the reconstructed site was observed with the Piehler procedure.</p><p><strong>Conclusion: </strong>Surgical outcomes for patients treated with b-CVRR after AAAD repair were acceptable. Intraoperative coronary artery events occurred due to stenosis caused by traction on the reconstructed coronary artery due to adhesions.</p>","PeriodicalId":12585,"journal":{"name":"General Thoracic and Cardiovascular Surgery","volume":" ","pages":"328-335"},"PeriodicalIF":1.1,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142106446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison of the short-term outcomes and the incidence of post-thoracotomy pain syndrome between dual-portal and multi-portal robotic-assisted thoracic surgery.","authors":"Hikaru Watanabe, Jun Suzuki, Hiroki Ebana, Naoki Kanauchi, Tetsuro Uchida, Satoshi Shiono","doi":"10.1007/s11748-025-02155-w","DOIUrl":"https://doi.org/10.1007/s11748-025-02155-w","url":null,"abstract":"<p><strong>Purpose: </strong>To compare the short-term outcomes and the incidence of post-thoracotomy pain syndrome following dual- versus multi-portal robotic-assisted thoracic surgery.</p><p><strong>Methods: </strong>We retrospectively analyzed a database of 287 patients from two institutions in Japan that perform dual- and multi-portal robotic-assisted thoracic surgery between September 2019 and August 2024. Patients underwent surgery for non-small cell lung cancer and were evaluated for short-term outcomes. Propensity score matching was performed to address differences in the patients' background characteristics between the two surgical groups. Logistic regression analyses were performed to identify the risk factors for post-thoracotomy pain syndrome after robotic-assisted thoracotomy.</p><p><strong>Results: </strong>Before matching and compared with the multi-portal group, the dual-portal group underwent fewer segmentectomies (p = 0.002) and had fewer dissected lymph nodes (p = 0.014). Patient's characteristics were similar between the groups after matching. There was no significant difference in the short-term perioperative outcomes of both groups. The dual-portal group experienced a significantly lower rate of post-thoracotomy pain syndrome than the multi-portal group (p = 0.038). The predictive factors for post-thoracotomy pain syndrome in the multivariate analysis were multi-portal thoracic surgery and postoperative complications.</p><p><strong>Conclusions: </strong>The short-term outcomes after dual- and multi-portal robotic-assisted thoracic surgery were comparable. However, multi-portal surgery was a predictive factor for post-thoracotomy pain syndrome.</p>","PeriodicalId":12585,"journal":{"name":"General Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143966803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Melissa A Austin, Danial Ahmad, Jake L Rosen, Matthew P Weber, Indranee Rajapreyar, Jesus Eduardo Rame, Rene J Alvarez, John W Entwistle, Howard T Massey, Vakhtang Tchantchaleishvili
{"title":"Impact of waitlist weight change on outcomes in heart transplant recipients: a UNOS database analysis.","authors":"Melissa A Austin, Danial Ahmad, Jake L Rosen, Matthew P Weber, Indranee Rajapreyar, Jesus Eduardo Rame, Rene J Alvarez, John W Entwistle, Howard T Massey, Vakhtang Tchantchaleishvili","doi":"10.1007/s11748-024-02078-y","DOIUrl":"10.1007/s11748-024-02078-y","url":null,"abstract":"<p><strong>Background: </strong>While the effect of pre-transplant weight on patient outcomes following heart transplantation (HTx) has previously been studied, data regarding the impact of dynamic weight change prior to HTx are extremely limited.</p><p><strong>Objectives: </strong>We sought to elucidate the interaction between HTx listing weight and weight change while waitlisted, and explore how that interaction impacts post-HTx survival in a continuous manner.</p><p><strong>Methods: </strong>Adult patients listed for HTx from 1987 to 2020 were identified from UNOS database. Three-dimensional restricted cubic spline analysis explored post-HTx survival relative to both changes in BMI/weight and BMI at time of HTx listing. Continuous predictor variables were analyzed with Cox proportional hazards method.</p><p><strong>Results: </strong>9,628 included patients underwent HTx. Median recipient age was 55 [IQR 46-62] years, and 21% were females. 53% of patients lost while 47% gained weight on the waitlist. Median BMI (27.6 kg/m<sup>2</sup> [24.3-31.3] vs. 27.4 kg/m<sup>2</sup> [24.2-30.9], paired p < 0.001) and weight (84.8 kg [73.0-98.0] kg vs. 84.4 kg [72.6-96.6], p < 0.001) were similar at listing and transplant. One-year survival was 89.3%. Weight loss over 3 BMI points or 10 kg was associated with higher hazard of death irrespective of listing BMI. In non-obese patients, some weight gain (1-4 BMI points or 5-15 kg) was associated with improved survival. In cachectic patients (BMI < 18.5), failure to gain weight was associated with worse survival.</p><p><strong>Conclusions: </strong>Impact of weight change varies depending on listing BMI. While a survival benefit is seen in non-obese patients who gain some weight, significant weight loss is associated with poorer survival.</p>","PeriodicalId":12585,"journal":{"name":"General Thoracic and Cardiovascular Surgery","volume":" ","pages":"336-342"},"PeriodicalIF":1.1,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11993457/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142365020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Survival impact of pathologic features after salvage lung resection following definitive chemoradiotherapy or systemic therapy for initially unresectable lung cancer.","authors":"Naoyuki Oka, Tomoyuki Hishida, Kaoru Kaseda, Yuri Suzuki, Yu Okubo, Kyohei Masai, Keisuke Asakura, Katsura Emoto, Hisao Asamura","doi":"10.1007/s11748-024-02086-y","DOIUrl":"10.1007/s11748-024-02086-y","url":null,"abstract":"<p><strong>Purpose: </strong>Salvage surgery for primary lung cancer is expected to become increasingly common. This study aimed to clarify the survival impact of pathologic characteristics after salvage surgery.</p><p><strong>Methods: </strong>Consecutive patients who underwent salvage surgery following definitive chemoradiotherapy or systemic therapy for initially unresectable lung cancer from 2010 to 2020 were enrolled in this study. The tumor slides were reviewed to determine the size of the tumor bed and the proportions of viable tumor, necrosis, and stroma.</p><p><strong>Results: </strong>A total of 23 patients were evaluated, and 18 had clinical stage IIIB-IV disease. Six received chemoradiotherapy and 17 received systemic therapy alone. A major pathologic response (MPR, ≤ 10% of viable tumor) was observed in 6 patients, and 4 patients achieved a pathological complete response. The 3-year overall and recurrence-free survival rates (OS and RFS) were 78.6% and 59.2%, respectively. There was no significant difference in OS between patients with and without MPR, and even non-MPR patients achieved a favorable 3-year OS of 70.2%. Meanwhile, patients with high (≥ 30%) stroma showed significantly better OS than those with low (< 30%) stroma (3-year OS: 100% vs. 23.3%, p < 0.001).</p><p><strong>Conclusions: </strong>This study showed that the proportion of stroma can be useful for predicting long-term survival after salvage surgery. Further large-scale studies are warranted to confirm the current findings.</p>","PeriodicalId":12585,"journal":{"name":"General Thoracic and Cardiovascular Surgery","volume":" ","pages":"362-371"},"PeriodicalIF":1.1,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142344892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Guanghua Huang, Li Wang, Zhewei Zhao, Yadong Wang, Bowen Li, Zhicheng Huang, Xiaoqing Yu, Naixin Liang, Shanqing Li
{"title":"Development and internal validation of predictive models for spread through air spaces in clinical stage IA lung adenocarcinoma.","authors":"Guanghua Huang, Li Wang, Zhewei Zhao, Yadong Wang, Bowen Li, Zhicheng Huang, Xiaoqing Yu, Naixin Liang, Shanqing Li","doi":"10.1007/s11748-025-02152-z","DOIUrl":"https://doi.org/10.1007/s11748-025-02152-z","url":null,"abstract":"<p><strong>Objective: </strong>Spread through air spaces (STAS) in lung adenocarcinoma impacted prognosis and treatment decisions, but lacked reliable preoperative prediction. We aimed to construct an easy-to-use model for clinical stage IA adenocarcinoma patients.</p><p><strong>Methods: </strong>This study analyzed 1212 patients with clinical stage IA lung adenocarcinoma undergoing lung resections from November 2020 to January 2022. Two logistic regression models were developed. Model 1 used demographic and computed tomography features, and Model 2 incorporated maximum standardized uptake values additionally. Internal validation used tenfold cross-validation. Model discrimination and calibration were described by the area under the curve (AUC) and Spiegelhalter z test, respectively.</p><p><strong>Results: </strong>Prevalence of STAS was 10.6%. Model 1 consisted of maximum tumor diameter, smoking history, location, spiculation and lobulation, showing moderate discrimination (AUC = 0.700). Model 2 consisted of smoking history, the maximum standardized uptake value, spiculation and lobulation, receiving an AUC of 0.807 and good calibration. Model 2 has a sensitivity and a specificity of 0.857 and 0.652. A nomogram for Model 2 was also developed.</p><p><strong>Conclusion: </strong>Our study developed and validated two predictive models for STAS for clinical stage IA lung adenocarcinoma. Model 2, integrating maximum standardized uptake value, outperformed Model 1 and offered a more comprehensive approach to predicting STAS. Surgeon could consider the results of Model 2 and intraoperative frozen sections sequentially to optimize surgical strategies. External validation remained warranted.</p>","PeriodicalId":12585,"journal":{"name":"General Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143961377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yu Hohri, Kavya Rajesh, Megan M Chung, Elizabeth L Norton, Christopher He, Yanling Zhao, Paul Kurlansky, Bradley Leshnower, Edward P Chen, Hiroo Takayama
{"title":"Aortic valve-sparing operation at concomitant aortic root and total aortic arch replacement.","authors":"Yu Hohri, Kavya Rajesh, Megan M Chung, Elizabeth L Norton, Christopher He, Yanling Zhao, Paul Kurlansky, Bradley Leshnower, Edward P Chen, Hiroo Takayama","doi":"10.1007/s11748-025-02150-1","DOIUrl":"https://doi.org/10.1007/s11748-025-02150-1","url":null,"abstract":"<p><strong>Objective: </strong>Sparing aortic valve during combined aortic root replacement (ARR) and total aortic arch replacement (TAR) adds surgical complexity; however, the long-term outcomes are unknown. We examine the safety of aortic valve-sparing during these operations.</p><p><strong>Methods: </strong>To include patients who were potentially eligible for valve-sparing procedures, aortic stenosis, endocarditis, and previous aortic valve surgery were excluded, leaving 81 patients who underwent ARR and TAR between 2004 and 2021 at 2 major aortic centers. Overall, 34 underwent valve-sparing aortic root replacement (VSRR) and 47 underwent composite valve graft root replacement (CVG). The primary endpoint was uneventful recovery: a composite endpoint describing any patient discharged from the hospital without mortality or any postoperative complications including stroke, re-operation for bleeding, prolonged ventilation, or acute renal failure. Secondary endpoints were long-term survival and cardiovascular reintervention at 12 years.</p><p><strong>Results: </strong>VSRR was more frequently performed in younger patients with connective tissue disorder (P = 0.006) and less than moderate aortic insufficiency (P = 0.002). VSRR had longer cross-clamp time (243, [200-286] vs. 216, [181-250] minutes, P = 0.032). In-hospital mortality (VSRR: 5.9% vs CVG: 10.6%, P = 0.693) and uneventful recovery (VSRR: 47.1% vs CVG: 44.7%, P = 1.000) were not different. Multivariable Logistic regression showed that VSRR was not associated with the uneventful recovery (OR 1.165, 95% CI [0.356-3.814], P = 0.801). Twelve-year survival (VSRR: 80.8% [63.1-100.0%] vs. CVG: 66.3% [47.9-91.7%]; P = 0.320) and the incidence of reintervention (VSRR: 39.0% [19.0-59.0%] vs. CVG: 39.0% [16.0-61.0%], P = 0.820) were similar between groups.</p><p><strong>Conclusion: </strong>In appropriately selected patients requiring concomitant ARR and TAR, aortic valve-sparing operation may be performed safely.</p>","PeriodicalId":12585,"journal":{"name":"General Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143982574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Takuya Watanabe, Takefumi Doi, Hiromitsu Domen, Yoshinori Handa, Hitoshi Igai, Jun Suzuki, Akihiro Taira, Masayuki Tanahashi, Takashi Suda
{"title":"Uniportal video-assisted thoracoscopic surgery for lung cancer: the current opinions and future perspectives of thoracic surgeons in Japan.","authors":"Takuya Watanabe, Takefumi Doi, Hiromitsu Domen, Yoshinori Handa, Hitoshi Igai, Jun Suzuki, Akihiro Taira, Masayuki Tanahashi, Takashi Suda","doi":"10.1007/s11748-025-02151-0","DOIUrl":"https://doi.org/10.1007/s11748-025-02151-0","url":null,"abstract":"<p><strong>Objectives: </strong>Uniportal video-assisted thoracoscopic surgery (U-VATS) is gaining global recognition as a minimally invasive approach. However, its current status and issues in Japan remain unclear. This study aimed to assess U-VATS adoption and barriers among Japanese thoracic surgeons through a nationwide survey.</p><p><strong>Methods: </strong>The Japanese Uniportal VATS Interest Group conducted an online survey of 3287 thoracic surgeons on the Japan Association for Chest Surgery mail list. Responses were collected from October 25 to November 30, 2024, yielding 851 valid responses (25.9%) from 497 institutions (78.0% of JACS-registered institutions).</p><p><strong>Results: </strong>The adoption rate of U-VATS among the institutions was 42.5%. However, the proportions of thoracic surgeons who primarily performed lobectomy, segmentectomy, and wedge resection using U-VATS were 10.3%, 10.2%, and 22.0%, respectively. The main reasons for non-adoption included concerns regarding safety and surgical precision (57.2%), preference for other approaches (50.9%), and lack of instruments (48.8%). Among surgeons with no prior U-VATS experience, 34.1% were willing to adopt it. To facilitate broader adoption, respondents highlighted the need for troubleshooting resources (61.3%), high-precision surgical videos (59.0%), and hands-on training programs (51.5%).</p><p><strong>Conclusion: </strong>Despite the relatively high institutional adoption rate, the proportion of thoracic surgeons using U-VATS as the primary approach remained low. Key barriers include concerns about safety and surgical precision, limited educational opportunities, and a lack of scientific evidence on U-VATS in Japan. To promote the wider adoption of U-VATS, it is essential to develop structured educational programs and generate evidence to ensure both safety and surgical precision.</p>","PeriodicalId":12585,"journal":{"name":"General Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143982596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sosei Abe, Yuichiro Ueda, So Miyahara, Takashi Ueda, Toshihiko Sato
{"title":"Utility of interfacility patient transfer after radiofrequency identification marker placement for precise sublobar resection of small pulmonary nodules.","authors":"Sosei Abe, Yuichiro Ueda, So Miyahara, Takashi Ueda, Toshihiko Sato","doi":"10.1007/s11748-025-02149-8","DOIUrl":"https://doi.org/10.1007/s11748-025-02149-8","url":null,"abstract":"<p><strong>Objectives: </strong>Introduction of the radiofrequency identification (RFID) marking system has enabled the precise localization of small pulmonary nodules, facilitating precise sublobar lung resection (PSR). However, the necessary hybrid operating room (HOR) for such precision procedures is mainly available in advanced medical institutions and not universally accessible. Performance of marker placement and lung resection at different facilities without the HOR can promote the widespread adoption of PSR.</p><p><strong>Methods: </strong>We retrospectively analyzed the data of five patients who underwent thoracoscopic PSR at Fukuoka University Hospital after placement of RFID markers under cone beam computed tomography guidance at the Fukuoka Seisyukai Hospital from March to June 2024.</p><p><strong>Results: </strong>In all patients, the RFID marker was successfully placed in the intended locations, and no marker migration and no clinical complications occurred during patient transfer from the Fukuoka Seisyukai Hospital to Fukuoka University Hospital. All patients underwent uneventful simultaneous marker removal and lesion resection within 72 h of marker placement.</p><p><strong>Conclusion: </strong>It is feasible to transfer a patient to another facility after placing an RFID marker and subsequently perform PSR.</p>","PeriodicalId":12585,"journal":{"name":"General Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144010404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Analysis of the changes in health-related quality of life and employment status after surgery in patients with lung cancer: a single-center longitudinal study.","authors":"Yuka Kadomatsu, Toru Oga, Atsuhiko Ota, Hiroshi Yatsuya, Yuta Kawasumi, Harushi Ueno, Taketo Kato, Shota Nakamura, Tetsuya Mizuno, Toyofumi Fengshi Chen-Yoshikawa","doi":"10.1007/s11748-025-02144-z","DOIUrl":"https://doi.org/10.1007/s11748-025-02144-z","url":null,"abstract":"<p><strong>Objective: </strong>This study analyzed the changes in health-related quality of life (HRQOL) and employment status of patients undergoing lung cancer surgery in Japan.</p><p><strong>Methods: </strong>This was a single-center, prospective study on patients who underwent lung anatomical resection. The eligible patients completed self-reported HRQOL and employment surveys at baseline and 6 and 12 months postoperatively. HRQOL was assessed using questionnaires including the European Organization for Research and Treatment of Cancer Core Quality of Life questionnaire (EORTC QLQ-C30) and EORTC QLQ and Lung Cancer module and additional social engagement and work-related stress evaluation tools.</p><p><strong>Results: </strong>In total, 93 patients completed the baseline survey, and 80 provided survey data at 6 months postoperatively. The HRQOL scores of several factors significantly declined immediately after the surgery and then gradually improved. The EORTC global health score, which represents overall health status, returned to baseline levels at 12 months postoperatively. However, symptoms such as fatigue, dyspnea, and coughing did not return to baseline levels at 12 months postoperatively. Approximately 68% of the patients who were employed preoperatively continued to work at 12 months postoperatively.</p><p><strong>Conclusions: </strong>Lung cancer surgery significantly affected the HRQOL and employment status of the patients within the first 6 months after surgery. For patients who decide to return to work before full recovery of QOL, we consider the need for enhanced support to assist them as they can reintegrate into work and activities of daily living.</p>","PeriodicalId":12585,"journal":{"name":"General Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143968583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}