Frontiers in Neurology最新文献

{"title":"Selective correlation of hippocampal volumes with WADA memory scores in mesial temporal sclerosis patients.","authors":"Lourdes Khalife, Wassim Nasreddine, Fatima Jaafar, Huda Abboodi, Karim Nasreddine, Ahmad Beydoun","doi":"10.3389/fneur.2025.1507846","DOIUrl":"https://doi.org/10.3389/fneur.2025.1507846","url":null,"abstract":"<p><strong>Objective: </strong>The WADA test is used to determine cerebral language dominance and assess the risk of postoperative amnesia following mesial temporal lobe resection. This study aims to explore the correlation between automated measures of hippocampal volume and WADA memory scores and to evaluate whether these volumetric measurements can reliably predict WADA memory scores.</p><p><strong>Methods: </strong>This study included patients who underwent a comprehensive presurgical assessment along with bilateral WADA testing. Hippocampal volumes were measured from high-resolution brain MRIs using automated software (volBrain), which were harmonized and normalized to whole brain volume. These harmonized and normalized volumes were then correlated with ipsilateral WADA memory scores and stratified according to brain MRI findings. A similar analysis was conducted between hippocampal volume asymmetry and WADA memory score asymmetry (WMA). A Receiver Operating Characteristic (ROC) curve was generated to compare the sensitivity and specificity in predicting successful WADA outcomes based on ipsilateral harmonized normalized hippocampal volumes.</p><p><strong>Results: </strong>In patients with mesial temporal sclerosis (MTS), significant positive correlations were found between harmonized normalized hippocampal volumes and ipsilateral WADA memory scores, as well as between harmonized hippocampal volume asymmetries and WMA. However, no significant correlations were found in patients with epileptogenic lesions other than MTS or those with normal brain MRIs. A harmonized normalized hippocampal volume threshold of ≥ 28.94 units was identified as a predictor of a WADA memory score exceeding 50% following contralateral carotid artery injection, with a sensitivity of 62.1% and a specificity of 100%.</p><p><strong>Significance: </strong>This study indicates that hippocampal volumetry could potentially serve as an alternative to the WADA test in patients with MTS. Conversely, in individuals with normal MRI results or other types of epileptogenic lesions, hippocampal volumetry does not reliably predict memory deficits, necessitating the use of the WADA test or functional MRI for planning resections of mesial temporal structures in the dominant hemisphere.</p>","PeriodicalId":12575,"journal":{"name":"Frontiers in Neurology","volume":"16 ","pages":"1507846"},"PeriodicalIF":2.7,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11802426/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143382144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stem cell-derived exosome treatment for acute spinal cord injury: a systematic review and meta-analysis based on preclinical evidence.","authors":"Chunlin Mou, Ziyao Xia, Xiujuan Wang, Xunan Dai, Jiaxian Wang, Chun Zhang, Yongsheng Xu","doi":"10.3389/fneur.2025.1447414","DOIUrl":"https://doi.org/10.3389/fneur.2025.1447414","url":null,"abstract":"<p><strong>Background: </strong>The study aims were to systematically review and analyze preclinical research on the efficacy of exosomes derived from various mesenchymal stem cell sources (MSC-exos) for the treatment of spinal cord contusion injury (SCI) in small animal models.</p><p><strong>Methods: </strong>We conducted a systematic search of PubMed, Embase and Google Scholar databases from their inception through February 29, 2024, to identify eligible English-language studies based on predefined inclusion and exclusion criteria. Two independent investigators performed literature screening, data extraction and bias assessment.</p><p><strong>Results: </strong>A total of 235 rats were used to assess locomotor recovery at the initial assessment, and exhibited significant improvement in hind limb movement in those treated with exosomes, as indicated by a statistically significant increase in Basso-Beattie-Bresnahan (BBB) scores (MD: 1.26, 95% CI: 1.14-1.38, <i>p</i> < 0.01) compared to the controls. This trend persisted in final assessment data across 21 studies, with pooled analysis confirming similar results (MD: 1.56, 95% CI: 1.43-1.68, <i>p</i> < 0.01). Funnel plot analysis indicated asymmetry in the pooled BBB scores at both baseline and endpoint assessments, suggesting potential publication bias. Exosomes were derived from bone marrow, adipose tissue, umbilical cord or human placental MSCs. Meta-analysis results showed no statistically significant differences in therapeutic efficacy among these MSC-exos sources at various treatment time points.</p><p><strong>Conclusion: </strong>MSC-exos demonstrated considerable promise in improving motor function in SCI-affected rats, with bone marrow MSC-derived exosomes having particularly notable effectiveness.</p>","PeriodicalId":12575,"journal":{"name":"Frontiers in Neurology","volume":"16 ","pages":"1447414"},"PeriodicalIF":2.7,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11802430/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143382170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of glycolysis on ischemic stroke: from molecular mechanisms to clinical applications.","authors":"Yingquan Liu, Peijia Hu, Hongliang Cheng, Fangyuan Xu, Yu Ye","doi":"10.3389/fneur.2025.1514394","DOIUrl":"https://doi.org/10.3389/fneur.2025.1514394","url":null,"abstract":"<p><p>Ischemic stroke (IS), a leading cause of disability and mortality worldwide, remains a significant challenge due to its complex pathogenesis. Glycolysis, a central metabolic pathway, plays a critical role in bridging the gap between metabolic dysfunction and neurological impairment. During ischemic conditions, glycolysis replaces oxidative phosphorylation as the primary energy source for brain tissue. However, in the ischemia-reperfusion state, neuronal cells show a particular reliance on aerobic glycolysis. Immune cells, such as monocytes, also contribute to atheromatous plaque formation and thrombi through increased aerobic glycolysis. Given glycolysis's involvement in various pathological stages of IS, it offers the potential for improved diagnosis, treatment, and prevention. This review comprehensively explores the role of glycolysis in different phases of IS, addresses existing controversies, and discusses its diagnostic and therapeutic applications. By elucidating the intricate relationship between glycolysis and IS, this review aims to provide novel insights for future research and clinical advancements.</p>","PeriodicalId":12575,"journal":{"name":"Frontiers in Neurology","volume":"16 ","pages":"1514394"},"PeriodicalIF":2.7,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11802445/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143382171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk factors for perioperative cerebral infarction in moyamoya disease: a meta-analysis.","authors":"Jincan Wu, Shiju Li, Ruixin Liang, Yanxu Wang, Fangyuan Shi, Xiaoming Pan, Xinyi Chen","doi":"10.3389/fneur.2025.1530137","DOIUrl":"https://doi.org/10.3389/fneur.2025.1530137","url":null,"abstract":"<p><strong>Background: </strong>The present study explored the risk factors for cerebral infarction perioperative moyamoya disease by meta-analysis.</p><p><strong>Methods: </strong>The PubMed, Embase, Cochrane library, Web of science databases were searched for case-control/cohort studies on risk factors for the emergence of cerebral infarction perioperative moyamoya disease, the search was done from the database creation to June 1, 2024, and the data was analyzed by using stata15.0.</p><p><strong>Result: </strong>Ten retrospective cohort studies (<i>N</i> = 3,239) were included. Meta-analysis results suggested posterior cerebral artery involvement [OR = 2.62, 95%CI (1.36, 5.06)], preoperative magnetic resonance angiography [OR = 2.81, 95%CI (1.27, 6.22)], previous infarction [OR = 2.52, 95% CI (1.69, 3.75)] were risk factor for the development of cerebral infarction perioperative moyamoya disease.</p><p><strong>Conclusion: </strong>This study proves that posterior cerebral artery involvement and grade of preoperative magnetic resonance angiography is higher, and the previous infarction happened moyamoya disease a risk factor for cerebral infarction. Therefore, people with these risk factors should be intervened in advance to prevent the occurrence of perioperative cerebral infarction.</p>","PeriodicalId":12575,"journal":{"name":"Frontiers in Neurology","volume":"16 ","pages":"1530137"},"PeriodicalIF":2.7,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11802441/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143382142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of interictal epileptiform discharges and serum concentration of levetiracetam and lamotrigine.","authors":"Johannes D Lang, Alexander Willno, Caroline Reindl, Tamara Welte, Jenny Stritzelberger, Stephanie Gollwitzer, Katrin Walther, Hajo Hamer","doi":"10.3389/fneur.2024.1524637","DOIUrl":"https://doi.org/10.3389/fneur.2024.1524637","url":null,"abstract":"<p><strong>Background: </strong>Interictal epileptiform discharges (IEDs) are an electrographic biomarker of epilepsy. Despite their crucial role in diagnosing epilepsy, heterogeneous findings exist on the mechanisms underlying their occurrence and the effects of anti-seizure medications (ASMs) on IEDs.</p><p><strong>Methods: </strong>We conducted a study to investigate the association between IED frequency and the serum concentration of two commonly used ASMs, levetiracetam (LEV) and lamotrigine (LTG). We included 56 patients undergoing a continuous video EEG monitoring in our center with tapering of ASM. IED frequency was analyzed using automated and semiautomated methods and serum samples were collected sequentially throughout the stay.</p><p><strong>Results: </strong>The cohort consisted of 41 patients (23 female, 18 male), between 19 and 64 years (mean 37.42 years), most of which were diagnosed with focal epilepsy (93%). IED frequency increased after ASM reduction revealing a negative correlation similarly with LEV and LTG serum concentrations (<i>p</i> = 0.0057 and <i>p</i> = 0.0426, respectively).</p><p><strong>Discussion: </strong>Notably, we observed a significant increase in IED frequency following dose reduction or discontinuation of both medications. This effect was reversed after ASM were re-dosed. This may indicate the suppressive properties of LEV and LTG against epileptic seizures. Furthermore, our study highlights the importance of ASM discontinuation, which may be required for capturing IEDs during diagnostic continuous EEG monitoring, and not be fully explained by circadian or ultradian rhythms alone.</p><p><strong>Conclusion: </strong>Our findings contribute to the understanding of ASM effects on IED frequency dynamics and suggest seizure suppressive properties of LEV and LTG.</p>","PeriodicalId":12575,"journal":{"name":"Frontiers in Neurology","volume":"15 ","pages":"1524637"},"PeriodicalIF":2.7,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11802410/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143382197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical efficacy of Tuina therapy combined with traditional Chinese exercises in the treatment of symptomatic lumbar disc herniation: a multicentre randomised controlled trial protocol.","authors":"Zhihong Fan, Shenghong Jia, Xin Zhou, Chao Li, Jiahao Shao, Xiaofeng Liu, Yitao Liao, Yenan Xu, Dandan He, Shixiang Wu, Xian Zhang","doi":"10.3389/fneur.2025.1497933","DOIUrl":"https://doi.org/10.3389/fneur.2025.1497933","url":null,"abstract":"<p><strong>Background: </strong>Low back pain and lower extremity sensory and functional abnormalities are common symptoms of lumbar disc herniation (LDH), which can easily cause walking dysfunction and significantly impair the quality of life of patients. Tuina and traditional Chinese exercises (TCEs) are effective in relieving pain and restoring dysfunction, and both are often used in China as a combination of passive therapy and active exercise to ease symptoms in patients with LDH. However, the majority of current clinical trials on the treatment of LDH with Tuina or TCEs are single-centre clinical studies, and the quality of these studies is generally low. Furthermore, clear evidence of clinical efficacy as to whether Tuina combined with TCEs is superior to single TCEs for improving dysfunction and pain in patients with LDH is lacking.</p><p><strong>Methods/design: </strong>The design is a multicentre, assessor-blinded clinical randomised controlled trial. A total of 166 patients with LDH (aged 18-65 years) were recruited from four centres and randomly assigned at a 1:1 ratio to two groups: the TCE group and the Tuina combined with the TCE group. Each group received three treatments over the course of 1 week for a total of 4 weeks. The primary outcome indicator was the Oswestry Disability Index, whereas the secondary outcome indicators were the Short Form of Quality of Life Scale, the Short-Form McGill Pain Questionnaire Scale, and gait analysis. Assessments were made before the treatment, at the end of the treatment, and at the third and sixth months' follow-ups. Gait analysis was only used for comparison between the two groups before and after treatment, and did not involve follow-up. Adverse events occurring during the trial were faithfully recorded.</p><p><strong>Conclusion: </strong>The results of this study are expected to provide a more effective research protocol for symptomatic LDH and an evidence-based rationale for the efficacy and safety of Tuina combined with TCEs in the treatment of symptomatic LDH.</p><p><strong>Clinical trial registration: </strong>https://www.chictr.org.cn/showproj.html?proj=209956, identifier ChiCTR2300077361.</p>","PeriodicalId":12575,"journal":{"name":"Frontiers in Neurology","volume":"16 ","pages":"1497933"},"PeriodicalIF":2.7,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11802433/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143382137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Siemens Healthineers' StrokeSegApp for automated diffusion and perfusion lesion segmentation in patients with ischemic stroke.","authors":"Lynnet-Samuel J Teichmann, Ahmed A Khalil, Kersten Villringer, Jochen B Fiebach, Stefan Huwer, Eli Gibson, Ivana Galinovic","doi":"10.3389/fneur.2025.1518477","DOIUrl":"https://doi.org/10.3389/fneur.2025.1518477","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to evaluate the perfomance of Siemens Healthineers' StrokeSegApp performance in automatically segmenting diffusion and perfusion lesions in patients with acute ischemic stroke and to assess its clinical utility in guiding mechanical thrombectomy decisions.</p><p><strong>Methods: </strong>This retrospective study used MRI data of acute ischemic stroke patients from the prospective observational single-center 1000Plus study, acquired between September 2008 and June 2013 (clinicaltrials.org; NCT00715533) and manually segmented by radiologists as the ground truth. The performance of the StrokeSegApp was compared against this ground truth using the dice similarity coefficient (DSC) and Bland-Altman plots. The study also evaluated the application's ability to recommend mechanical thrombectomy based on DEFUSE 2 and 3 trial criteria.</p><p><strong>Results: </strong>The StrokeSegApp demonstrated a mean DSC of 0.60 (95% CI: 0.57-0.63; <i>n</i> = 241) for diffusion deficit segmentation and 0.80 (95% CI: 0.76-0.85; <i>n</i> = 56) for perfusion deficit segmentation. The mean volume deviation was 0.49 mL for diffusion lesions and -7.69 mL for perfusion lesions. Out of 56 subjects meeting DEFUSE 2/3 criteria in the cohort, it correctly identified mechanical thrombectomy candidates with a sensitivity of 82.1% (95% CI: 63.1-93.9%) and a specificity of 96.4% (95% CI: 81.7-99.9%).</p><p><strong>Conclusion: </strong>The Siemens Healthineers' StrokeSegApp provides accurate automated segmentation of ischemic stroke lesions, comparable to human experts as well as similar commercial software, and shows potential as a reliable tool in clinical decision-making for stroke treatment.</p>","PeriodicalId":12575,"journal":{"name":"Frontiers in Neurology","volume":"16 ","pages":"1518477"},"PeriodicalIF":2.7,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11804811/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143382140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cartilage graft and temporal muscle fascia graft in revision myringoplasty: a comparison of anatomical and functional results with an innovative surgical technique.","authors":"Andrea Canale, Marco Boldreghini, Ili Abboud, Patrizia Peluso, Elisa Vestrini, Gluseppe Riva, Andrea Albera","doi":"10.3389/fneur.2024.1497162","DOIUrl":"https://doi.org/10.3389/fneur.2024.1497162","url":null,"abstract":"<p><strong>Background: </strong>The temporal muscle fascia is the most widely used type of tissue graft in revision myringoplasty procedures. The aim of this study was to verify if the use of a cartilage graft may be a valid alternative to temporalis fascia. Tympanic reperforations are frequent after myringoplasty, especially in complicated, large, or anterior perforations, so we decided to compare the neodrum stability of two different surgical techniques.</p><p><strong>Materials and methods: </strong>The study was conducted on 42 patients who underwent revision myringoplasty, carried out with the overlay technique, between 2004 and 2020. In all patients, the retroauricular approach was used. The subjects included in the study were divided into 2 groups: the former was treated with a cartilage graft, while in the latter a temporalis fascia graft was used. In the comparison of the two groups, the following outcomes were taken into consideration: engraftment rate, incidence of complications, pre- and postoperative air conduction pure tone average and air-bone gap.</p><p><strong>Results: </strong>The success rate was 100% for the first group and 83.3% for the second, with a statistically not significant difference. Among the subjects treated with cartilage graft, complications were observed in 8.3% of the cases, while in patients treated with fascia graft the observed complication rate was 43.3% (<i>p</i> = 0.03), maybe due to the shorter follow-up period of the first group. The improvement of the air conduction pure tone average was greater with cartilage graft (<i>p</i> = 0.02), whereas the difference between air-bone gap closures in the two groups was not statistically significant.</p><p><strong>Conclusion: </strong>The cartilage graft can represent a valid alternative to temporal muscle fascia, guaranteeing excellent engraftment, fewer complication rate and satisfactory hearing outcomes.</p>","PeriodicalId":12575,"journal":{"name":"Frontiers in Neurology","volume":"15 ","pages":"1497162"},"PeriodicalIF":2.7,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11804253/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143382199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of endolymphatic hydrops on wideband acoustic immittance and otoacoustic emissions in guinea pigs.","authors":"Huan Lin, Xuanyi Li, Huiying Zhang, Yi Mu, Xi Wang, Naveena Konduru, Renlong Ji, Wen Liu, Zhao Fei, Wen Jiang, Yuehua Qiao","doi":"10.3389/fneur.2025.1444928","DOIUrl":"10.3389/fneur.2025.1444928","url":null,"abstract":"<p><strong>Background: </strong>Inner ear disorders, such as EH, commonly lead to hearing loss and vestibular dysfunction. EH is particularly prevalent in various inner ear diseases, including Meniere's disease. We aimed to evaluate the effects of EH on WAI and OAEs.</p><p><strong>Objective: </strong>This study explores the potential of wideband acoustic immittance (WAI) and otoacoustic emissions (OAEs) for the early detection of changes in acoustic transmission associated with vasopressin-induced endolymphatic hydrops (EH) in a guinea pig model.</p><p><strong>Methods: </strong>We induced EH in guinea pigs via daily intraperitoneal injections of arginine vasopressin over 14 consecutive days. Auditory function was assessed using Auditory Brainstem Responses (ABR), while changes in sound energy transmission were measured using WAI and Distortion Products Otoacoustic Emissions (DPOAE).</p><p><strong>Results: </strong>Increased ABR thresholds in EH models were statistically significant (<i>p</i> < 0.05). After 14 days of EH induction, absorbance at 1 kHz significantly increased, whereas it significantly decreased at 4 kHz and 6 kHz (<i>p</i> < 0.05). DPOAE measures, both magnitude and phase, showed no significant changes (<i>p</i> > 0.05).</p><p><strong>Conclusion: </strong>WAI demonstrates greater sensitivity than DPOAE in the early detection of acoustic transmission alterations in EH models, suggesting its utility as a diagnostic tool in early-stage inner ear disorders.</p>","PeriodicalId":12575,"journal":{"name":"Frontiers in Neurology","volume":"16 ","pages":"1444928"},"PeriodicalIF":2.7,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11800357/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143364363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"No need to rethink sensorimotor circuits-Commentary on Goldblatt et al. (2024).","authors":"Joel C Glover","doi":"10.3389/fneur.2025.1544855","DOIUrl":"10.3389/fneur.2025.1544855","url":null,"abstract":"","PeriodicalId":12575,"journal":{"name":"Frontiers in Neurology","volume":"16 ","pages":"1544855"},"PeriodicalIF":2.7,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11798807/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143364362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}